Genetics of hepatocellular carcinoma

scientific article

Genetics of hepatocellular carcinoma is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1006/SCBI.2000.0319
P698PubMed publication ID10936068
P5875ResearchGate publication ID223582888

P2093author name stringBuendia MA
P433issue3
P304page(s)185-200
P577publication date2000-06-01
P1433published inSeminars in Cancer BiologyQ1908668
P1476titleGenetics of hepatocellular carcinoma.
P478volume10

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cites work (P2860)
Q35991536A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.
Q37266967A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.
Q41472938A multicenter matched case-control analysis on seven polymorphisms from HMGB1 and RAGE genes in predicting hepatocellular carcinoma risk
Q28597820A novel KLF6-Rho GTPase axis regulates hepatocellular carcinoma cell migration and dissemination
Q47443676A4383C and C76G SNP in Cathepsin B is respectively associated with the high risk and tumor size of hepatocarcinoma
Q24607045ARID2: a new tumor suppressor gene in hepatocellular carcinoma
Q81424551Absence of KLF6 gene mutation in 71 hepatocellular carcinomas
Q42735941Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion
Q37447362Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.
Q45585418Allelic loss of chromosome 4q21 approximately 23 associates with hepatitis B virus-related hepatocarcinogenesis and elevated alpha-fetoprotein
Q57205409Allelic loss of chromosome 4q21?23 associates with hepatitis B virus-related hepatocarcinogenesis and elevated alpha-fetoprotein
Q39419389Allelic loss on chromosome 5q34 is associated with poor prognosis in hepatocellular carcinoma
Q24291237An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors
Q43778437Anticancer potential of rhamnocitrin 4'-β-D-galactopyranoside against N-diethylnitrosamine-induced hepatocellular carcinoma in rats.
Q46099165Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma.
Q53658904Association Between a Variant in ADAMTS5 and the Susceptibility to Hepatocellular Carcinoma in a Chinese Han Population.
Q34599939Association of GST genetic polymorphisms with the susceptibility to hepatocellular carcinoma (HCC) in Chinese population evaluated by an updated systematic meta-analysis
Q33290022Beclin 1 mRNA strongly correlates with Bcl-XLmRNA expression in human hepatocellular carcinoma
Q44534101Beta-catenin mutations in liver tumors induced by 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in CDF1 mice
Q36792873Bioinformatics analysis of the gene expression profile of hepatocellular carcinoma: preliminary results
Q35131908Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation.
Q45001863Characterization of a conserved aphidicolin-sensitive common fragile site at human 4q22 and mouse 6C1: possible association with an inherited disease and cancer
Q34565424Clinical and microdissection genotyping analyses of the effect of intra-arterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma
Q33801311Clinical implications of hepatitis B virus mutations: recent advances
Q45910989Clinical significance of PICT1 in patients of hepatocellular carcinoma with wild-type TP53.
Q37220672Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellular carcinoma
Q35010949Clinicopathological significance of loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in China
Q24291548Cloning and characterization of F-LANa, upregulated in human liver cancer
Q30926657Cloning and characterization of human IC53-2, a novel CDK5 activator binding protein.
Q91870878Co-expression analysis and ceRNA network reveal eight novel potential lncRNA biomarkers in hepatocellular carcinoma
Q36923010Combined effects of p53 and MDM2 polymorphisms on susceptibility and surgical prognosis in hepatitis B virus-related hepatocellular carcinoma.
Q36397275Control of cell migration: a tumour suppressor function for p53?
Q36543797Control of differentiation in progression of epithelial tumors
Q42091512Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma.
Q24296626DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control
Q41970979DLEC1 Expression Is Modulated by Epigenetic Modifications in Hepatocelluar Carcinoma Cells: Role of HBx Genotypes
Q36993940Deregulation of epigenetic mechanisms by the hepatitis B virus X protein in hepatocarcinogenesis
Q35664806Dickkopf-1 activates cell death in MDA-MB435 melanoma cells
Q52967770Diminished transcription of chromosome arm 4q is inversely related to local spreading of hepatocellular carcinoma.
Q36926103Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer
Q36497062Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
Q36792334Effects of HMGB1 Polymorphisms on the Susceptibility and Progression of Hepatocellular Carcinoma
Q40312516Enhanced cell survival of Hep3B cells by the hepatitis B x antigen effector, URG11, is associated with upregulation of beta-catenin
Q38521564Enhanced expression of matrix metalloproteinase-9 by hepatitis B virus infection in liver cells
Q38212153Epithelial-mesenchymal transition: molecular pathways of hepatitis viruses-induced hepatocellular carcinoma progression
Q34327140Evidence for association with hepatocellular carcinoma at the PAPSS1 locus on chromosome 4q25 in a family-based study
Q35010167Expression of beta-catenin in hepatocellular carcinoma
Q43649359Expression profiling and identification of novel genes in hepatocellular carcinomas
Q35721877Focus on hepatocellular carcinoma.
Q40503818Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma
Q36313998From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma
Q34389709From chronic liver disorders to hepatocellular carcinoma: Molecular and genetic pathways
Q73932372GSK-3beta phosphorylation and alteration of beta-catenin in hepatocellular carcinoma
Q36129235Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors
Q34850055Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects
Q35851186Genetic alterations of hepatocellular carcinoma by random amplified polymorphic DNA analysis and cloning sequencing of tumor differential DNA fragment
Q33711037Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma
Q40460745Genetic susceptibility of eight nonsynonymous polymorphisms in HLA-DRB1 gene to hepatocellular carcinoma in Han Chinese.
Q80581092Genomic instability in hepatocellular carcinoma revealed by using the random amplified polymorphic DNA method
Q36474291Genomic instability of murine hepatocellular carcinomas with low and high metastatic capacities
Q44559769Genomic progression in mouse models for liver tumors
Q36388400HBV induced carcinogenesis
Q46669089HBx-mediated miR-21 upregulation represses tumor-suppressor function of PDCD4 in hepatocellular carcinoma
Q34138263Harnessing transposons for cancer gene discovery
Q44706836Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells.
Q41826006Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis
Q58021990Hepatitis B virus and hepatocellular carcinoma
Q34398029Hepatitis viruses and hepatocarcinogenesis
Q29615841Hepatocellular carcinoma
Q39460817Hepatocellular carcinoma: a systems biology perspective
Q38083250Human hepatocyte carcinogenesis (review).
Q38183539Hydrodynamic transfection for generation of novel mouse models for liver cancer research
Q34598012Identification of a structural motif crucial for infectivity of hepatitis B viruses
Q74434735Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma
Q34331690Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of beta-catenin in the liver.
Q24292045Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients
Q43037592Identification, using cDNA macroarray analysis, of distinct gene expression profiles associated with pathological and virological features of hepatocellular carcinoma
Q33787939Immunohistochemical analysis of p53, cyclinD1, RB1, c-fos and N-ras gene expression in hepatocellular carcinoma in Iran
Q48003450Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer
Q40314768Insulin-like growth factor-I stimulates H4II rat hepatoma cell proliferation: dominant role of PI-3'K/Akt signaling
Q42166898Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo
Q40282309Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma
Q34399237Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression
Q36917485Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.
Q38613586Liver cell transformation in chronic HBV infection
Q37889223Liver development and cancer formation in zebrafish.
Q28592004Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
Q58814520Localization of a susceptibility locus for hepatocellular carcinoma to chromosome 4q in a hepatitis B hyperendemic area
Q44796636Long-term high-dose interferon-α therapy delays Hepadnavirus-related hepatocarcinogenesis in X/myc transgenic mice
Q38625154Loss of p53 and Ink4a/Arf cooperate in a cell autonomous fashion to induce metastasis of hepatocellular carcinoma cells
Q37843945Loss of runt-related transcription factor 3 causes development and progression of hepatocellular carcinoma
Q33785451Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis
Q35678361Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers
Q40390047Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11.
Q33680701Molecular genetics of hepatocellular neoplasia.
Q35260040Molecular mechanisms underlying hepatocellular carcinoma
Q74543031Molecular pathogenesis of human hepatocellular carcinoma
Q36618666Molecular signatures associated with HCV-induced hepatocellular carcinoma and liver metastasis
Q27490350Mouse models in liver cancer research: A review of current literature
Q28213290Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
Q35094277Mutations in TP53 and CTNNB1 in Relation to Hepatitis B and C Infections in Hepatocellular Carcinomas from Thailand
Q39012794Nanomedicine in management of hepatocellular carcinoma: Challenges and opportunities
Q36740642New molecular targets for hepatocellular carcinoma: the ErbB1 signaling system
Q44226601New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism
Q36519041New therapies for hepatocellular carcinoma.
Q37418293Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function.
Q28246572Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver
Q40346356Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations
Q78537160P53 mutation as a source of aberrant beta-catenin accumulation in cancer cells
Q40203803PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression.
Q39377876PTEN: A potential prognostic marker in virus-induced hepatocellular carcinoma.
Q33279919Pleiotropic effects of PI-3' kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosis
Q37457851Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression
Q33838680Postgenomic technologies targeting the Wnt signaling network
Q53297765Pre-"EMT"ing key processes in liver carcinogenesis: Growing evidence for how malignant hepatocytes invade and conquer.
Q37564060Prognostic significance of p53, mTOR, c-Met, IGF-1R, and HSP70 overexpression after the resection of hepatocellular carcinoma
Q40061408Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells
Q40263391Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma
Q34325518RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts
Q35988103Rapid identification of promoter hypermethylation in hepatocellular carcinoma by pyrosequencing of etiologically homogeneous sample pools
Q41008655Reconstitution of gene expression from a regulatory-protein-deficient hepatitis B virus genome by cell-permeable HBx protein
Q53391613Recurrent allelic deletions at mouse chromosomes 4 and 14 in Myc-induced liver tumors.
Q36062154Reduced efficacy of the Plk1 inhibitor BI 2536 on the progression of hepatocellular carcinoma due to low intratumoral drug levels
Q35919507Relevance between HLA-DP gene rs2281388 polymorphism and hepatocellular carcinoma risk
Q39496866Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus
Q87195036Role of VEGF-C gene polymorphisms in susceptibility to hepatocellular carcinoma and its pathological development
Q38824357Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma.
Q34852233Silencing of Pokemon enhances caspase-dependent apoptosis via fas- and mitochondria-mediated pathways in hepatocellular carcinoma cells
Q35695493Similarities and differences in hepatitis B and C virus induced hepatocarcinogenesis
Q40750117Specific association between alcohol intake, high grade of differentiation and 4q34-q35 deletions in hepatocellular carcinomas identified by high resolution allelotyping
Q35019588Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats.
Q44490652Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680].
Q42576509Staging systems in hepatocellular carcinoma
Q35795731Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance.
Q28485238Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells
Q54340913Survivin T9809C, an SNP located in 3'-UTR, displays a correlation with the risk and clinicopathological development of hepatocellular carcinoma.
Q42695569Synergetic anticancer effect of combined quercetin and recombinant adenoviral vector expressing human wild-type p53, GM-CSF and B7-1 genes on hepatocellular carcinoma cells in vitro
Q35078725TP53 and liver carcinogenesis.
Q41037020The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma
Q37606028The changing landscape of hepatocellular carcinoma: etiology, genetics, and therapy
Q53644880The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice.
Q36419017The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma.
Q35348787The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling
Q35605993The p53R172H mutant does not enhance hepatocellular carcinoma development and progression.
Q40626766The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.
Q34540302The silencing of Pokemon attenuates the proliferation of hepatocellular carcinoma cells in vitro and in vivo by inhibiting the PI3K/Akt pathway
Q33754980The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication
Q37468111The transcriptomic G1-G6 signature of hepatocellular carcinoma in an Asian population: Association of G3 with microvascular invasion.
Q57757025Treatment of hepatocellular carcinoma
Q35111116Vasohibin 2 decreases the cisplatin sensitivity of hepatocarcinoma cell line by downregulating p53.
Q30886599Viral hepatitis: new data on hepatitis C infection
Q35080930WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients
Q24653563Wnt signaling: the good and the bad
Q80234093[Precancerous lesions in the cirrhotic and non-cirrhotic liver]
Q39255366miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma
Q37042920p16 Stimulates CDC42-dependent migration of hepatocellular carcinoma cells
Q47840456p53 immunostaining pattern in Brazilian patients with hepatocellular carcinoma
Q36143616siRNA-mediated beta-catenin knockdown in human hepatoma cells results in decreased growth and survival
Q35083197βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin

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