Efficient lentiviral transduction of liver requires cell cycling in vivo

scientific article

Efficient lentiviral transduction of liver requires cell cycling in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1047582122
P356DOI10.1038/71673
P698PubMed publication ID10615126
P5875ResearchGate publication ID51360894

P2093author name stringOhashi K
Naldini L
Chiu W
Kay MA
Park F
P2860cites workSustained expression of genes delivered directly into liver and muscle by lentiviral vectorsQ45884182
Intramuscular injection of an adenoviral vector expressing hepatocyte growth factor facilitates hepatic transduction with a retroviral vector in miceQ64381551
Factors influencing retroviral-mediated gene transfer into hepatocytes in vivoQ72858896
Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral-mediated gene transfer in miceQ77220644
HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structureQ28283258
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vectorQ29547503
A third-generation lentivirus vector with a conditional packaging systemQ29616120
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivoQ29616612
Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cellsQ33783211
Integration of murine leukemia virus DNA depends on mitosisQ34051046
Stable and efficient gene transfer into the retina using an HIV-based lentiviral vectorQ36586077
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vectorQ37251114
Development of HIV vectors for anti-HIV gene therapyQ37251477
Nonproductive human immunodeficiency virus type 1 infection in nucleoside-treated G0 lymphocytesQ39595263
Moloney murine leukemia virus-derived retroviral vectors decay intracellularly with a half-life in the range of 5.5 to 7.5 hoursQ39881415
Human immunodeficiency virus infection of cells arrested in the cell cycleQ41531689
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectorsQ43716886
Hepatic gene therapy: persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivoQ45879739
L-histidinol provides effective selection of retrovirus-vector-transduced keratinocytes without impairing their proliferative potentialQ45880428
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)49-52
P577publication date2000-01-01
P1433published inNature GeneticsQ976454
P1476titleEfficient lentiviral transduction of liver requires cell cycling in vivo
P478volume24

Reverse relations

cites work (P2860)
Q3690602020-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease
Q3707877720-HETE-mediated cytotoxicity and apoptosis in ischemic kidney epithelial cells
Q44915884A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy
Q39733540A new hybrid system capable of efficient lentiviral vector production and stable gene transfer mediated by a single helper-dependent adenoviral vector
Q34497332AAV-mediated gene transfer for hemophilia
Q34124149Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.
Q40394484Adeno-associated virus-mediated bone morphogenetic protein-7 gene transfer induces C2C12 cell differentiation into osteoblast lineage cells
Q34329754Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction
Q41980779Altering α-dystroglycan receptor affinity of LCMV pseudotyped lentivirus yields unique cell and tissue tropism
Q44620413An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes
Q93353440Antiangiogenic Gene Therapy in Cancer
Q40099387Assembly of hepatitis B virus envelope proteins onto a lentivirus pseudotype that infects primary human hepatocytes
Q38693642Assessment of selected media supplements to improve F/HN lentiviral vector production yields.
Q37176481Back to the future: a recent history of haemophilia treatment
Q33285871Centrosomal latency of incoming foamy viruses in resting cells
Q38472381Conditional expression of a suicide gene by the telomere reverse transcriptase promoter for potential post-therapeutic deletion of tumorigenesis
Q44631505Correction of Bleeding Diathesis Without Liver Toxicity Using Arenaviral-Pseudotyped HIV-1–Based Vectors in Hemophilia A Mice
Q37931159Countering hepatitis B virus infection using RNAi: how far are we from the clinic?
Q40197541Critical assessment of lifelong phenotype correction in hyperbilirubinemic Gunn rats after retroviral mediated gene transfer
Q33565275Delivery of factor VIII gene into skeletal muscle cells using lentiviral vector
Q34019566Design of an HIV-1 lentiviral-based gene-trap vector to detect developmentally regulated genes in mammalian cells
Q30453447Development of an avian leukosis-sarcoma virus subgroup A pseudotyped lentiviral vector
Q33787285Development of multigene and regulated lentivirus vectors
Q39292167Development of packaging cell lines for generation of adeno-associated virus vectors by lentiviral gene transfer of trans-complementary components
Q44223354Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo
Q35596574Effects of vector backbone and pseudotype on lentiviral vector-mediated gene transfer: studies in infant ADA-deficient mice and rhesus monkeys
Q45888555Efficient gene transduction to cultured hepatocytes by HIV-1 derived lentiviral vector
Q45878744Emerging and receding risks of therapeutic regimens for haemophilia
Q40619697Engineered long terminal repeats of retroviral vectors enhance transgene expression in hepatocytes in vitro and in vivo
Q28586805Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis
Q35149966Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo
Q37512409Ex vivo gene delivery to hepatocytes: techniques, challenges, and underlying mechanisms
Q35919263Expression of exogenetic enhanced green fluorescent protein in rat endocranium through lentivirus infection
Q43188456Expression of papillomavirus L1 proteins regulated by authentic gene codon usage is favoured in G2/M-like cells in differentiating keratinocytes
Q35904452Fetal and neonatal gene therapy: benefits and pitfalls
Q37594766Foamy virus vectors for gene transfer
Q45885518Gene and antisense delivery in alcoholism research
Q34530130Gene therapy for haemophilia.
Q34368127Gene therapy for haemophilia: the end of a 'royal pathology' in the third millennium?
Q64379985Gene therapy for hemophilia
Q45160558Gene therapy for hemophilia: are viral vectors really feasible?
Q45877159Gene therapy for hemophilia? Yes.
Q37346064Gene therapy for liver enzyme deficiencies: what have we learned from models for Crigler-Najjar and tyrosinemia?
Q34997896Gene therapy for the central nervous system in the lysosomal storage disorders
Q64377524Gene therapy for the hemophilias
Q35630146Gene therapy in orthopaedic surgery: the current status
Q35208038Gene therapy of hepatocarcinoma: a long way from the concept to the therapeutical impact
Q34176027Gene therapy: a 2001 perspective
Q34497310Gene therapy: a brief overview of the past, present, and future
Q34636968Gene therapy: reality or myth for the global bleeding disorders community?
Q36230845Gene transfer for hemophilia: can therapeutic efficacy in large animals be safely translated to patients?
Q34375860Genetic engineering within the adult brain: implications for molecular approaches to behavioral neuroscience
Q44845534Helper-Independent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo
Q35181577Hemophilia: treatment options in the twenty-first century
Q40639511Hepatoma cell-specific ganciclovir-mediated toxicity of a lentivirally transduced HSV-TkEGFP fusion protein gene placed under the control of rat alpha-fetoprotein gene regulatory sequences
Q37644966Heritable and inducible gene knockdown in astrocytes or neurons in vivo by a combined lentiviral and RNAi approach.
Q40740222High efficiency lentiviral gene delivery in non-dividing cells by deoxynucleoside treatment
Q73298912High efficiency protein transduction of quiescent and proliferating primary hematopoietic cells
Q35666730Home management of haemophilia.
Q38183539Hydrodynamic transfection for generation of novel mouse models for liver cancer research
Q35828547Identification of a novel TGF-β-miR-122-fibronectin 1/serum response factor signaling cascade and its implication in hepatic fibrogenesis.
Q36105888In utero gene therapy: current challenges and perspectives.
Q40132247In vitro and in vivo induction of bone formation based on adeno-associated virus-mediated BMP-7 gene therapy using human adipose-derived mesenchymal stem cells
Q34328596In vivo assessment of gene delivery to keratinocytes by lentiviral vectors
Q34344453In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins
Q33691863In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector
Q44057415Intravenous administration of an E1/E3-deleted adenoviral vector induces tolerance to factor IX in C57BL/6 mice
Q40322398Jaagsiekte sheep retrovirus pseudotyped lentiviral vector-mediated gene transfer to fetal ovine lung
Q52172176Learning from lentiviruses.
Q35231284Lentiviral gene transfer into the dorsal root ganglion of adult rats
Q35865275Lentiviral vector design using alternative RNA export elements
Q73121677Lentiviral vectors
Q43954074Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes
Q39593815Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells
Q35149980Lentivirus vectors incorporating the immunoglobulin heavy chain enhancer and matrix attachment regions provide position-independent expression in B lymphocytes
Q42097990Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression.
Q35904443Liver gene therapy: advances and hurdles
Q35788586Liver repopulation by Bcl-x(L) transgenic hepatocytes
Q35989150Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy
Q44848775Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy
Q44536266Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice.
Q35003246Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents
Q55428320MicroRNA-125b Promotes Hepatic Stellate Cell Activation and Liver Fibrosis by Activating RhoA Signaling.
Q33576396Microporation is a valuable transfection method for efficient gene delivery into human umbilical cord blood-derived mesenchymal stem cells
Q34269646Molecular therapeutics of liver disease
Q37176506New assays for monitoring haemophilia treatment
Q43477694Newborn liver gene transfer by an HIV-2-based lentiviral vector.
Q44815512Non-invasive viral gene transfer of factor IX to colonic epithelial cells in hemophilia B mice
Q37061714Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells
Q33802664Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction
Q38905682Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies
Q45880348Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors.
Q42261436Osteogenic differentiation of human periodontal ligament cells after transfection with recombinant lentiviral vector containing follicular dendritic cell secreted protein
Q42846730Partial attenuation of cytotoxicity and apoptosis by SOD1 in ischemic renal epithelial cells
Q34609626Parvovirus-mediated gene transfer for the haemophilias
Q42199346Polyploidization without mitosis improves in vivo liver transduction with lentiviral vectors
Q35915704Preclinical and clinical gene therapy for haemophilia
Q42424129Priming of hepatocytes enhances in vivo liver transduction with lentiviral vectors in adult mice
Q43830772Production of human clotting Factor IX without toxicity in mice after vascular delivery of a lentiviral vector
Q35120176Progress and problems with the use of viral vectors for gene therapy
Q34354549Proline residues within spacer peptide p1 are important for human immunodeficiency virus type 1 infectivity, protein processing, and genomic RNA dimer stability
Q40221155Prolonged adherence of human immunodeficiency virus-derived vector particles to hematopoietic target cells leads to secondary transduction in vitro and in vivo
Q37678176Recent advances in lentiviral vector development and applications
Q45861906Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors
Q41866974Reversal of diabetes through gene therapy of diabetic rats by hepatic insulin expression via lentiviral transduction
Q34515859Slipping through the door: HIV entry into the nucleus
Q41734970Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
Q45873385Specific detection of human coagulation factor IX in cynomolgus macaques
Q37001594Staunch protections: the ethics of haemophilia gene transfer research
Q44966515Successful lentivirus-based delivery of NLS-LACZ gene into porcine hepatocytes
Q42819436Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis
Q45875852Sustained and therapeutic delivery of factor IX in nude haemophilia B mice by encapsulated C2C12 myoblasts: concurrent tumourigenesis.
Q41691498Sustained inhibition of hepatitis B virus replication in vivo using RNAi-activating lentiviruses
Q45855463Targeting vascular injury using Hantavirus-pseudotyped lentiviral vectors
Q45876374The Genetics of bleeding disorders: a report on the UK Haemophilia Centre Doctors' Organisation annual scientific symposium, 10th October 2003.
Q45863921The P-selectin cytoplasmic domain directs the cellular storage of a recombinant chimeric factor IX.
Q53652323The effect of age on hepatic gene transfer with self-inactivating lentiviral vectors in vivo.
Q36890651The intermediate conductance calcium-activated potassium channel KCa3.1 regulates vascular smooth muscle cell proliferation via controlling calcium-dependent signaling
Q45855320The measurement of low levels of factor VIII or factor IX in hemophilia A and hemophilia B plasma by clot waveform analysis and thrombin generation assay
Q34364782Transduction of interphase cells by avian sarcoma virus.
Q44519606Transplantation of murine bone marrow stromal cells under the kidney capsule to secrete coagulation factor VIII.
Q28141424Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

Search more.