scholarly article | Q13442814 |
P2093 | author name string | Ying Feng | |
Wei Dou | |||
Yu Shen | |||
Song Zhang | |||
Ying Leng | |||
Jian-hua Shen | |||
Jun-hua Chen | |||
Su-ling Huang | |||
P2860 | cites work | Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges | Q28096294 |
Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action | Q28204909 | ||
Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats | Q28369343 | ||
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation | Q28508582 | ||
Glucocorticoids, metabolism and metabolic diseases. | Q30362857 | ||
Classic and recent etiologies of Cushing's syndrome: diagnosis and therapy | Q30984797 | ||
A transgenic model of visceral obesity and the metabolic syndrome | Q34104691 | ||
Structure-based strategies for drug design and discovery | Q35748974 | ||
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis | Q35995063 | ||
11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action | Q36217956 | ||
11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice | Q36402808 | ||
Anti-cancer properties of anthraquinones from rhubarb | Q36615073 | ||
Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene | Q36724042 | ||
Isolation of a cDNA for the catalytic subunit of rat liver glucose-6-phosphatase: regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP. | Q36751840 | ||
11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress | Q36833926 | ||
An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects | Q36992538 | ||
Obesity and corticosteroids: 11beta-hydroxysteroid type 1 as a cause and therapeutic target in metabolic disease | Q37608720 | ||
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease | Q37742798 | ||
Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor alpha/gamma agonist on glucose uptake | Q38304139 | ||
Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets | Q39777522 | ||
Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation | Q41673139 | ||
Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice | Q42459262 | ||
Glucocorticoids down-regulate glucose uptake capacity and insulin-signaling proteins in omental but not subcutaneous human adipocytes. | Q42462690 | ||
Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes | Q42484332 | ||
Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice | Q43730363 | ||
Immunosuppressive effect of emodin, a free radical generator | Q43810833 | ||
Aloe emodin suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. | Q44036377 | ||
Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. | Q44273298 | ||
Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians | Q44467081 | ||
Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains | Q44576264 | ||
Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss | Q44741685 | ||
11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus | Q45050691 | ||
Cortisol secretion in relation to body fat distribution in obese premenopausal women | Q45252138 | ||
Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone. | Q45285404 | ||
Diet-induced type II diabetes in C57BL/6J mice | Q45730735 | ||
In vivo pharmacokinetics comparisons of icariin, emodin and psoralen from gan-kang granules and extracts of herba Epimedii, Nepal dock root, Ficus hirta yahl. | Q46005172 | ||
Hypoglycaemic and hypolipidaemic effects of emodin and its effect on L-type calcium channels in dyslipidaemic-diabetic rats | Q46373869 | ||
Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes | Q46404958 | ||
An all atom force field for simulations of proteins and nucleic acids | Q46625508 | ||
Development and application of a scintillation proximity assay (SPA) for identification of selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. | Q46717961 | ||
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity | Q46787475 | ||
Effect of dexamethasone on glucose tolerance and fat metabolism in a diet-induced obesity mouse model | Q46920977 | ||
Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice | Q47341892 | ||
Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice. | Q51463179 | ||
Emodin inhibits TNF-alpha-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis. | Q53476116 | ||
Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis. | Q53579867 | ||
Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation. | Q53584635 | ||
Anti-inflammatory effects of emodin from ventilago leiocarpa | Q71693452 | ||
Emodin-induced inhibition of growth and DNA damage in the Helicobacter pylori | Q74173332 | ||
Glucocorticoids and neuroendocrine function | Q74345554 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | obesity | Q12174 |
natural product | Q901227 | ||
hydroxysteroid | Q2157080 | ||
P304 | page(s) | 113-26 | |
P577 | publication date | 2010-09-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice | |
P478 | volume | 161 |
Q33631738 | 11β-HSD1 modulates LPS-induced innate immune responses in adipocytes by altering expression of PTEN. |
Q38067260 | 11β-Hydroxysteroid dehydrogenase type 1: potential therapeutic target for metabolic syndrome |
Q34253331 | 11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus. |
Q85931139 | A new triterpenoid from Teucrium viscidum |
Q47431887 | A systems approach to traditional oriental medicine |
Q36528888 | Anti-Inflammatory and Antinociceptive Activities of Anthraquinone-2-Carboxylic Acid |
Q37204963 | Association of Traditional Chinese Medicine Therapy and the Risk of Vascular Complications in Patients With Type II Diabetes Mellitus: A Nationwide, Retrospective, Taiwanese-Registry, Cohort Study. |
Q92435741 | Chrysophanol protects against doxorubicin-induced cardiotoxicity by suppressing cellular PARylation |
Q90627260 | Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-CoV-2 (2019-nCoV, COVID-19) coronavirus |
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Q51633356 | Emodin Decreases Hepatic Hypoxia-Inducible Factor-1[Formula: see text] by Inhibiting its Biosynthesis. |
Q54197498 | Emodin Inhibits Migration and Invasion of Human Endometrial Stromal Cells by Facilitating the Mesenchymal-Epithelial Transition Through Targeting ILK. |
Q37429748 | Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187. |
Q48506707 | Emodin alleviates alternatively activated macrophage and asthmatic airway inflammation in a murine asthma model. |
Q51593895 | Emodin alleviates hepatic steatosis by inhibiting sterol regulatory element binding protein 1 activity by way of the calcium/calmodulin-dependent kinase kinase-AMP-activated protein kinase-mechanistic target of rapamycin-p70 ribosomal S6 kinase sign |
Q38817374 | Emodin and Its Role in Chronic Diseases |
Q45352752 | Emodin and rhein decrease levels of hypoxia-inducible factor-1α in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells |
Q37184304 | Emodin attenuates systemic and liver inflammation in hyperlipidemic mice administrated with lipopolysaccharides |
Q50929191 | Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes. |
Q35102217 | Emodin enhances osteogenesis and inhibits adipogenesis |
Q34559604 | Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta |
Q85331689 | Emodin protects against diabetic cardiomyopathy by regulating the AKT/GSK-3β signaling pathway in the rat model |
Q36635928 | Emodin regulates glucose utilization by activating AMP-activated protein kinase |
Q36821624 | Emodin regulating excision repair cross-complementation group 1 through fibroblast growth factor receptor 2 signaling |
Q37729480 | Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice |
Q45769262 | Experimental diabetes treated with trigonelline: effect on β cell and pancreatic oxidative parameters |
Q36573908 | Genetic determinants of cardiometabolic risk: a proposed model for phenotype association and interaction |
Q51392149 | Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice. |
Q54354550 | Labisia pumila extract down-regulates hydroxysteroid (11-beta) dehydrogenase 1 expression and corticosterone levels in ovariectomized rats. |
Q28732458 | Lipidomics reveals multiple pathway effects of a multi-components preparation on lipid biochemistry in ApoE*3Leiden.CETP mice |
Q58696637 | Microbial Synthesis of Non-Natural Anthraquinone Glucosides Displaying Superior Antiproliferative Properties |
Q36993872 | Multi-mycotoxin screening reveals the occurrence of 139 different secondary metabolites in feed and feed ingredients |
Q34162991 | Nutritional supplements and their effect on glucose control |
Q91787489 | Pharmacological properties of Rheum turkestanicum Janisch |
Q54487719 | Phenolic diterpenes from rosemary suppress cAMP responsiveness of gluconeogenic gene promoters. |
Q33671491 | Screening of a natural compound library identifies emodin, a natural compound from Rheum palmatum Linn that inhibits DPP4. |
Q46762325 | Toxicity of anthraquinones: differential effects of rumex seed extracts on rat organ weights and biochemical and haematological parameters |
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