Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide

scientific article

Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.20052471
P932PMC publication ID3212725
P698PubMed publication ID16585267
P5875ResearchGate publication ID7195294

P50authorAllen SteereQ4731886
William W KwokQ88664294
Elise E DrouinQ105913302
William KlitzQ30322458
Gerald T NepomQ38546281
P2093author name stringBen A Falk
Lee Ann Baxter-Lowe
P2860cites workPractice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of AmericaQ44628961
HLA-DQ polymorphisms are highly selective for peptide binding interactions.Q45082483
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Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritisQ47762137
Molecular characterization of the OspA(161-175) T cell epitope associated with treatment-resistant Lyme arthritis: differences among the three pathogenic species of Borrelia burgdorferi sensu lato.Q53881935
Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1 alpha L is a partial agonist for outer surface protein A-reactive T cells.Q54013765
Binding of outer surface protein A and human lymphocyte function-associated antigen 1 peptides to HLA-DR molecules associated with antibiotic treatment-resistant Lyme arthritisQ57158927
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Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 allelesQ70248294
Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptidesQ72070645
Association of antibiotic treatment-resistant Lyme arthritis with T cell responses to dominant epitopes of outer surface protein A of Borrelia burgdorferiQ73065110
Lack of Borrelia burgdorferi DNA in synovial samples from patients with antibiotic treatment-resistant Lyme arthritisQ73313584
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferiQ22122357
Lyme DiseaseQ22250902
Detection of Borrelia burgdorferi DNA by Polymerase Chain Reaction in Synovial Fluid from Patients with Lyme ArthritisQ22250914
Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and miceQ24550778
HLA-DR2 subtypes form an additional supertypic family of DR beta allelesQ24605420
Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferiQ24642483
A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferiQ28144621
New HLA haplotype frequency reference standards: high-resolution and large sample typing of HLA DR-DQ haplotypes in a sample of European AmericansQ28207063
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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritisQ28306666
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The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritisQ33999945
Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme DiseaseQ34301091
Treatment of late Lyme borreliosis--randomised comparison of ceftriaxone and penicillinQ34560251
Host-adapted Borrelia burgdorferi in mice expresses OspA during inflammationQ35105901
Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramersQ35294749
Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II regionQ35644176
Elucidation of Lyme arthritisQ35709662
Cross-reactivity of T lymphocytes in infection and autoimmunityQ35895561
Juvenile rheumatoid arthritis and HLA: report of the Park City III workshopQ36151780
The T helper cell response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritisQ36364212
cDNA cloning and sequencing reveals that the electrophoretically constant DR beta 2 molecules, as well as the variable DR beta 1 molecules, from HLA-DR2 subtypes have different amino acid sequences including a hypervariable region for a functionallyQ36465640
MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigenQ36733217
Prognostic implications of HLA genotyping in the early assessment of patients with rheumatoid arthritisQ41132275
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectLyme diseaseQ201989
Lyme arthritisQ1878727
Borrelia burgdorferiQ2723634
P304page(s)961-71
P577publication date2006-04-17
P1433published inJournal of Experimental MedicineQ3186912
P1476titleAntibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide
P478volume203

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