Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function

scientific article

Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1365-2567.2008.03008.X
P3181OpenCitations bibliographic resource ID939682
P932PMC publication ID2632707
P698PubMed publication ID19120496
P5875ResearchGate publication ID23718242

P50authorEdward J PearceQ91529113
P2093author name stringJie Sun
Lucas Carvalho
Connie Krawczyk
Colleen Kane
Fraser Marshall
P2860cites workHelminth infections: the great neglected tropical diseasesQ24648324
Parasitic worms and inflammatory diseasesQ24669864
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaBQ28115656
The neglected tropical diseases: the ancient afflictions of stigma and poverty and the prospects for their control and eliminationQ28248682
Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivoQ28512204
Notch directly regulates Gata3 expression during T helper 2 cell differentiationQ28594834
Direct regulation of Gata3 expression determines the T helper differentiation potential of NotchQ28594879
Mycobacteria target DC-SIGN to suppress dendritic cell functionQ28616857
Dendritic cells: specialized and regulated antigen processing machinesQ29617085
Recognition of microorganisms and activation of the immune responseQ29617903
Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivoQ56880711
Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathologyQ57158211
Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activationQ57261983
Double-stranded RNAs from the Helminth ParasiteSchistosomaActivate TLR3 in Dendritic CellsQ57518104
Selective maturation of dendritic cells byNippostrongylus brasiliensis-secreted proteins drives Th2 immune responsesQ58843220
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasisQ59053989
Essential role for TLR4 and MyD88 in the development of chronic intestinal nematode infectionQ59549092
Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigensQ73242473
Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profileQ73520544
CD8- dendritic cell activation status plays an integral role in influencing Th2 response developmentQ74321435
Cutting edge: Th2 response induction by dendritic cells: a role for CD40Q77452185
Cutting edge: polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cellsQ77800961
Toll-like receptor 4 (TLR4) is required for protective immunity to larval Strongyloides stercoralis in miceQ79464597
TLR signalingQ79715393
Parasite-induced Th2 polarization is associated with down-regulated dendritic cell responsiveness to Th1 stimuli and a transient delay in T lymphocyte cyclingQ80418667
Impaired T helper 2 response to aeroallergen in helminth-infected patients with asthmaQ80895989
Helminth antigens modulate TLR-initiated dendritic cell activationQ81111451
Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiationQ81767249
Induction of enhanced immunity to intestinal nematodes using IL-9-producing dendritic cellsQ82459181
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21Q95814547
DC-SIGN mediates binding of dendritic cells to authentic pseudo-LewisY glycolipids of Schistosoma mansoni cercariae, the first parasite-specific ligand of DC-SIGN.Q33223117
Proteomic profiling reveals that Th2-inducing dendritic cells stimulated with helminth antigens have a 'limited maturation' phenotypeQ33322908
The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitroQ34563241
Control of adaptive immune responses by Toll-like receptors.Q34612562
Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergyQ35607506
Immune biasing by helminth glycans.Q35608898
Fibrotic disease and the T(H)1/T(H)2 paradigmQ35852270
Both free-living and parasitic nematodes induce a characteristic Th2 response that is dependent on the presence of intact glycansQ36228597
Regulatory T cells induced by parasites and the modulation of allergic responsesQ36279713
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigenQ36376615
Notch signaling is an important regulator of type 2 immunity.Q36403646
Suppression of allergic airway inflammation by helminth-induced regulatory T cellsQ36403704
IL-23 and IL-17 in tuberculosisQ37064619
Specifying helper T cell fates during immunityQ37114508
Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responsesQ37235037
The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.Q38356935
Modulation of the allergic reactivity of slum children by helminthic infectionQ39041063
Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infectionQ40184958
A helminth glycan induces APC maturation via alternative NF-kappa B activation independent of I kappa B alpha degradationQ40388500
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarizationQ40700194
Th2 differentiation is unaffected by Jagged2 expression on dendritic cellsQ41875479
Suppression of Th2 cell development by Notch ligands Delta1 and Delta4Q41962999
Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasitesQ42595867
Echinococcus granulosus antigen B impairs human dendritic cell differentiation and polarizes immature dendritic cell maturation towards a Th2 cell responseQ42800205
Carbohydrate components of Taenia crassiceps metacestodes display Th2-adjuvant and anti-inflammatory properties when co-injected with bystander antigenQ43480723
Schistosome N-glycans containing core alpha 3-fucose and core beta 2-xylose epitopes are strong inducers of Th2 responses in miceQ43525129
Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type responseQ43648201
Impairment of dendritic cell function by excretory-secretory products: a potential mechanism for nematode-induced immunosuppressionQ44203897
Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.Q44268237
Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cellsQ44306886
Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetesQ44474619
In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) settingQ45069275
Full development of Th2 immunity requires both innate and adaptive sources of CD154.Q45770822
Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responsesQ47218007
Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanismQ47368677
Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cellsQ47438852
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cellsQ47619638
A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cellsQ47810460
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathwaysQ48219736
Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses.Q52924766
Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.Q52956682
Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/- mice.Q52994753
TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.Q53875132
Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells.Q54559083
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
hygieneQ162297
cell functionQ95674809
P304page(s)28-34
P577publication date2009-01-01
P1433published inImmunologyQ15754984
P1476titleReview series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function
P478volume126

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