Notch directly regulates Gata3 expression during T helper 2 cell differentiation

scientific journal article

Notch directly regulates Gata3 expression during T helper 2 cell differentiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IMMUNI.2007.04.018
P3181OpenCitations bibliographic resource ID794761
P932PMC publication ID2801546
P698PubMed publication ID17658278
P5875ResearchGate publication ID6181249

P2093author name stringYumi Yashiro-Ohtani
Cristina Del Bianco
Dawson M. Knoblock
Stephen C. Blacklow
Terry C. Fang
Warren S. Pear
P2860cites workRegulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signalingQ47607371
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cellsQ47619638
Notch signaling augments T cell responsiveness by enhancing CD25 expressionQ47640384
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genesQ50111962
The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.Q50726643
Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene.Q51045931
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.Q51069614
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.Q51083007
Notch1 expression in early lymphopoiesis influences B versus T lineage determination.Q51085324
Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells.Q51999239
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.Q52117223
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses.Q54600658
Cutting edge: chromatin remodeling at the IL-4/IL-13 intergenic regulatory region for Th2-specific cytokine gene clusterQ73306717
Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin levelQ73835273
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivoQ73998192
A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cellsQ74548143
The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3Q74601841
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiationQ77769108
Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control regionQ81120000
Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expressionQ81375599
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21Q95814547
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptorsQ24290574
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexesQ24307538
p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitroQ24537773
p300 acts as a transcriptional coactivator for mammalian Notch-1Q24548267
Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complexQ28184514
Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and humanQ28215575
Critical roles for transcription factor GATA-3 in thymocyte developmentQ28511459
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cellsQ29614226
The lineage decisions of helper T cellsQ29614841
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomesQ34048667
Molecular mechanisms regulating Th1 immune responsesQ35034059
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cellsQ35834668
Regulation of lymphoid development, differentiation, and function by the Notch pathway.Q36072476
The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.Q36227978
Notch signaling is an important regulator of type 2 immunity.Q36403646
Regulation of Th2 differentiation and Il4 locus accessibility.Q36427376
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.Q39697358
Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.Q40517723
Notch 1 signaling regulates peripheral T cell activationQ40566978
Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3.Q41001778
Alternative promoters regulate transcription of the mouse GATA-2 geneQ41061961
Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elementsQ41097827
Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cellsQ41712990
Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansionQ43628952
TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cellsQ44576462
Deficient T cell fate specification in mice with an induced inactivation of Notch1.Q45345200
Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.Q45345202
Notch signaling controls the generation and differentiation of early T lineage progenitorsQ45345206
Notch1 expression on T cells is not required for CD4+ T helper differentiationQ47431184
Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cellsQ47438852
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
GATA binding protein 3Q21497809
Notch 1Q21986193
Recombination signal binding protein for immunoglobulin kappa J regionQ21990370
P304page(s)100–110
P577publication date2007-07-01
P1433published inImmunityQ6005457
P1476titleNotch directly regulates Gata3 expression during T helper 2 cell differentiation
P478volume27

Reverse relations

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