scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Sung-Yun Pai | |
I-Cheng Ho | |||
Tzong-Shyuan Tai | |||
P2860 | cites work | Expression of tal-1 and GATA-binding proteins during human hematopoiesis | Q24337571 |
Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene | Q24561490 | ||
DNA-binding specificities of the GATA transcription factor family | Q24603801 | ||
Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2 | Q82176327 | ||
Regulation of lineage commitment distinct from positive selection. | Q51084799 | ||
Notch1 expression in early lymphopoiesis influences B versus T lineage determination. | Q51085324 | ||
MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent. | Q51115513 | ||
Notch signaling is necessary for GATA3 function in the initiation of T cell development. | Q51960652 | ||
Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity. | Q52043550 | ||
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. | Q52117223 | ||
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. | Q55066450 | ||
GATA-3 Promotes Maturation, IFN-γ Production, and Liver-Specific Homing of NK Cells | Q58478744 | ||
Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism | Q61357092 | ||
Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter | Q70178242 | ||
Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level | Q73835273 | ||
Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells | Q74137391 | ||
A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells | Q74548143 | ||
Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus | Q77924879 | ||
Cutting edge: the differential involvement of the N-finger of GATA-3 in chromatin remodeling and transactivation during Th2 development | Q78346665 | ||
Critical YxKxHxxxRP motif in the C-terminal region of GATA3 for its DNA binding and function | Q79287363 | ||
Stat5 activation plays a critical role in Th2 differentiation | Q79291245 | ||
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus | Q80587027 | ||
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection | Q81483894 | ||
GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland | Q24649647 | ||
Development of all CD4 T lineages requires nuclear factor TOX | Q24652128 | ||
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model | Q24657350 | ||
Crystal Structures of Multiple GATA Zinc Fingers Bound to DNA Reveal New Insights into DNA Recognition and Self-Association by GATA | Q27651158 | ||
Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and human | Q28215575 | ||
Essential role of Stat6 in IL-4 signalling | Q28276199 | ||
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene | Q28276209 | ||
TH17 cells in development: an updated view of their molecular identity and genetic programming | Q28276449 | ||
The biology of NKT cells | Q28277482 | ||
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis | Q28505151 | ||
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3 | Q28511275 | ||
Critical roles for transcription factor GATA-3 in thymocyte development | Q28511459 | ||
Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3 | Q28511685 | ||
Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system | Q28512290 | ||
GATA-3: an unexpected regulator of cell lineage determination in skin | Q28512924 | ||
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells | Q28585402 | ||
Transcription factor GATA-3 is required for development of the T-cell lineage | Q28587190 | ||
GATA-3 regulates the development and function of invariant NKT cells | Q28590905 | ||
Notch directly regulates Gata3 expression during T helper 2 cell differentiation | Q28594834 | ||
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch | Q28594879 | ||
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells | Q29614226 | ||
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting | Q29614543 | ||
Distinct structural requirements of GATA-3 for the regulation of thymocyte and Th2 cell differentiation. | Q30366992 | ||
Critical functions for c-Myb at three checkpoints during thymocyte development | Q30433753 | ||
Molecular identity of hematopoietic precursor cells emerging in the human embryo. | Q31978561 | ||
Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway | Q33288223 | ||
Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin. | Q33715031 | ||
Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells | Q33830673 | ||
GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene | Q33924853 | ||
A mechanism for the initiation of allergen-induced T helper type 2 responses | Q34010133 | ||
Progression of regulatory gene expression states in fetal and adult pro-T-cell development | Q34150401 | ||
Signal strength in thymic selection and lineage commitment. | Q34167971 | ||
An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines | Q34191294 | ||
New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision | Q34547220 | ||
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation | Q34573593 | ||
T cell development: bottoms-up | Q34671215 | ||
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice | Q34831201 | ||
CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals | Q35824059 | ||
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells | Q35834668 | ||
Signaling pathways in Th2 development | Q35951832 | ||
Receptor signals and nuclear events in CD4 and CD8 T cell lineage commitment | Q36070683 | ||
Regulation of lymphoid development, differentiation, and function by the Notch pathway. | Q36072476 | ||
Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. | Q36119225 | ||
HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells | Q36171328 | ||
The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. | Q36227978 | ||
Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes | Q36364765 | ||
Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells | Q36370932 | ||
Role of the transcription factor Th-POK in CD4:CD8 lineage commitment | Q36382776 | ||
Commitment issues: linking positive selection signals and lineage diversification in the thymus | Q36382781 | ||
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors | Q36391825 | ||
CD4/CD8 lineage commitment: light at the end of the tunnel? | Q36397545 | ||
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment | Q36403025 | ||
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors | Q36403344 | ||
Regulation of Th2 differentiation and Il4 locus accessibility. | Q36427376 | ||
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells | Q36604402 | ||
Notch signalling during peripheral T-cell activation and differentiation | Q36684906 | ||
GATA-3 - not just for Th2 cells anymore | Q36755958 | ||
Development in motion: helper T cells at work | Q36785612 | ||
Control points in NKT-cell development | Q36858868 | ||
Interleukin 2 plays a central role in Th2 differentiation. | Q37095134 | ||
RUNX proteins in transcription factor networks that regulate T-cell lineage choice | Q37376016 | ||
The different faces of Notch in T-helper-cell differentiation | Q37376021 | ||
Enforced expression of the GATA-3 transcription factor affects cell fate decisions in hematopoiesis | Q38297965 | ||
GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers | Q38299593 | ||
Structure and specificity of GATA proteins in Th2 development | Q38302372 | ||
Calcineurin B1 is essential for positive but not negative selection during thymocyte development | Q39679218 | ||
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. | Q39697358 | ||
Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. | Q40517723 | ||
Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro | Q40575680 | ||
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. | Q40683787 | ||
Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. | Q40922234 | ||
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene | Q41093086 | ||
Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis | Q41650230 | ||
GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene | Q41653357 | ||
DNA-binding specificity of GATA family transcription factors | Q42078566 | ||
c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3. | Q42082679 | ||
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage | Q42220100 | ||
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling | Q42254951 | ||
Function of GATA transcription factors in preadipocyte-adipocyte transition | Q42835284 | ||
Interaction between GATA-3 and the transcriptional coregulator Pias1 is important for the regulation of Th2 immune responses | Q43684415 | ||
Deficient T cell fate specification in mice with an induced inactivation of Notch1. | Q45345200 | ||
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. | Q46001789 | ||
GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation | Q46044258 | ||
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling | Q47607371 | ||
Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. | Q48075133 | ||
Enforced expression of GATA-3 severely reduces human thymic cellularity | Q49057606 | ||
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes | Q50111962 | ||
The initial response of CD4+ IL-4-producing cells. | Q50699300 | ||
The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. | Q50726643 | ||
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. | Q50777703 | ||
CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus. | Q50799741 | ||
The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. | Q50977520 | ||
Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice. | Q51064947 | ||
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. | Q51083007 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell differentiation | Q210861 |
P304 | page(s) | 125-35 | |
P577 | publication date | 2009-02-01 | |
P1433 | published in | Nature Reviews Immunology | Q43355 |
P1476 | title | GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation | |
P478 | volume | 9 |
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Q35145136 | Boswellic acid attenuates asthma phenotypes by downregulation of GATA3 via pSTAT6 inhibition in a murine model of asthma |
Q33611408 | Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover |
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Q50727753 | GATA3 mutations define a unique subtype of luminal-like breast cancer with improved survival. |
Q41717443 | GATA3 regulates FLG and FLG2 expression in human primary keratinocytes |
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