Control points in NKT-cell development

scientific article published on July 2007

Control points in NKT-cell development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1051655275
P356DOI10.1038/NRI2116
P698PubMed publication ID17589542
P5875ResearchGate publication ID6247017

P50authorDale I GodfreyQ56957983
P2093author name stringStuart P Berzins
P2860cites workA distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1dQ24676253
Identification of a homozygous deletion in the AP3B1 gene causing Hermansky-Pudlak syndrome, type 2Q24685566
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramidesQ28254991
XIAP deficiency in humans causes an X-linked lymphoproliferative syndromeQ28271832
The biology of NKT cellsQ28277482
NKT cells derive from double-positive thymocytes that are positively selected by CD1dQ28508188
The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cellsQ28512367
GATA-3 regulates the development and function of invariant NKT cellsQ28590905
Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.Q32105308
Development of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7Q33782527
Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogenyQ33935873
Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor beta repertoire and small clone sizeQ33947957
Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.Q34053547
Positive and negative selection of T cellsQ34157557
Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chainQ34356372
Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.Q34597428
Differential antitumor immunity mediated by NKT cell subsets in vivoQ34603019
A unique lymphotoxin {alpha}beta-dependent pathway regulates thymic emigration of V{alpha}14 invariant natural killer T cellsQ34694902
Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiencyQ34762274
IL-15 availability conditions homeostasis of peripheral natural killer T cellsQ34807830
Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammalsQ35749602
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiencyQ35749606
Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic OntogenyQ63363297
A subset of CD4+ thymocytes selected by MHC class I moleculesQ72671900
Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cellsQ73481251
Cutting edge: influence of the TCR V beta domain on the avidity of CD1d:alpha-galactosylceramide binding by invariant V alpha 14 NKT cellsQ73496332
Cutting edge: the Ets1 transcription factor is required for the development of NK T cells in miceQ73520498
Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumorsQ73889862
Homeostasis of V alpha 14i NKT cellsQ74817607
IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferationQ77658417
T Cell Development in Mice Expressing CD1d Directed by a Classical MHC Class II PromoterQ79125440
Expression of CD1d Under the Control of a MHC Class Ia Promoter Skews the Development of NKT Cells, But Not CD8+ T CellsQ79125443
Regulatory roles of NKT cells in the induction and maintenance of cyclophosphamide-induced toleranceQ79401061
Slamf1, the NKT cell control gene Nkt1Q79609724
Cutting edge: impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 proteinQ79754919
An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell populationQ81354592
Regulation of NKT cell development by SAP, the protein defective in XLPQ81402277
Targeted expression of human CD1d in transgenic mice reveals independent roles for thymocytes and thymic APCs in positive and negative selection of Valpha14i NKT cellsQ81512239
Cutting edge: influence of the TCR Vbeta domain on the selection of semi-invariant NKT cells by endogenous ligandsQ82459119
Analysis of the effect of different NKT cell subpopulations on the activation of CD4 and CD8 T cells, NK cells, and B cellsQ82857040
Genetic and functional analysis of the Nkt1 locus using congenic NOD mice: improved Valpha14-NKT cell performance but failure to protect against type 1 diabetesQ82984613
DOCK2 is required in T cell precursors for development of Valpha14 NK T cellsQ83059294
Comparative gene expression analysis of NKT cell subpopulationsQ83337497
A thymic precursor to the NK T cell lineageQ95783850
T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cellsQ35848548
Going both ways: immune regulation via CD1d-dependent NKT cellsQ35951531
Signaling for NKT cell development: the SAP-FynT connectionQ36076597
Chewing the fat on natural killer T cell development.Q36227953
Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseasesQ36227994
A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.Q36228473
The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cellsQ36229257
Mechanisms imposing the Vbeta bias of Valpha14 natural killer T cells and consequences for microbial glycolipid recognitionQ36238065
MTP regulated by an alternate promoter is essential for NKT cell developmentQ36267165
Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytesQ36363308
Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of miceQ36363483
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.Q36363643
Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytesQ36365532
Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramersQ36368804
A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stageQ36370202
Distinct functional lineages of human V(alpha)24 natural killer T cellsQ36370354
Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer stainingQ36370359
CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cellsQ36370736
NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cellsQ36370941
The Src family tyrosine kinase Fyn regulates natural killer T cell developmentQ36375458
Lineage relationships and differentiation of natural killer (NK) T cells: intrathymic selection and interleukin (IL)-4 production in the absence of NKR-P1 and Ly49 moleculesQ36377137
Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cellsQ36380304
Induction of differentiation of pre-NKT cells to mature Valpha14 NKT cells by granulocyte/macrophage colony-stimulating factorQ36396689
The cell surface receptor SLAM controls T cell and macrophage functionsQ36399495
The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cellsQ36400520
Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene productQ36402758
Characterization of the early stages of thymic NKT cell developmentQ36402797
Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytesQ36403175
In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramersQ36404648
Increased thymic B cells but maintenance of thymic structure, T cell differentiation and negative selection in lymphotoxin-alpha and TNF gene-targeted miceQ36511394
Requirement for membrane lymphotoxin in natural killer cell development.Q37206961
Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activationQ37358144
Development of Valpha4+ NK T cells in the early stages of embryogenesisQ37527374
Testing the NKT cell hypothesis of human IDDM pathogenesisQ39738424
Thio-isoglobotrihexosylceramide, an agonist for activating invariant natural killer T cells.Q40208296
Lysosomal glycosphingolipid recognition by NKT cellsQ40493118
CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responsesQ40517634
Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cellsQ40600420
The Paradox of Immune Molecular Recognition of α-Galactosylceramide: Low Affinity, Low Specificity for CD1d, High Affinity for αβ TCRsQ40653197
NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.Q41719930
The influence of CD1d in postselection NKT cell maturation and homeostasisQ42483693
Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramideQ42601793
An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cellsQ42942523
Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell developmentQ42944908
Negative selection in the thymus includes semimature T cellsQ42947706
NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturationQ44113021
Thymocyte expression of cathepsin L is essential for NKT cell developmentQ44170965
Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell developmentQ44608949
Differential proliferative response of NKT cell subpopulations to in vitro stimulation in presence of different cytokinesQ44787834
Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogenyQ44885062
Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipidsQ45050713
Efficient activation of Valpha14 invariant NKT cells by foreign lipid antigen is associated with concurrent dendritic cell-specific self recognitionQ45214973
Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursorsQ46553571
Distinct homeostatic requirements of CD4+ and CD4- subsets of Valpha24-invariant natural killer T cells in humansQ46718817
A cell-type specific CD1d expression program modulates invariant NKT cell development and functionQ46902170
Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3).Q46927341
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cellsQ47765721
Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B.Q47810582
NKT cells: what's in a name?Q47895830
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infectionsQ50092191
Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus.Q51998750
Long-term retention of mature NK1.1+ NKT cells in the thymus.Q52022963
Development of CD1d-restricted NKT cells in the mouse thymus.Q52085666
Valpha24-JalphaQ-independent, CD1d-restricted recognition of alpha-galactosylceramide by human CD4(+) and CD8alphabeta(+) T lymphocytes.Q52119708
Membrane lymphotoxin is required for the development of different subpopulations of NK T cells.Q52167165
CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.Q53565669
NF-kappa B controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes.Q53644080
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.Q54626090
Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell FunctionsQ58328314
Thymic dependence of invariant Vα14+ Natural Killer-T cell developmentQ58478772
Limited correlation between human thymus and blood NKT?cell content revealed by an ontogeny study of paired tissue samplesQ60489505
Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studiesQ60489534
CD1d-Restricted NKT Cells: An Interstrain ComparisonQ62230429
Three day neonatal thymectomy selectively depletes NK1.1+ T cellsQ62230521
Differential alteration of lipid antigen presentation to NKT cells due to imbalances in lipid metabolismQ63259010
P433issue7
P304page(s)505-518
P577publication date2007-07-01
P1433published inNature Reviews ImmunologyQ43355
P1476titleControl points in NKT-cell development
P478volume7

Reverse relations

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