review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Gail A Bishop | Q56650269 |
P2093 | author name string | Gail A Bishop | |
P2860 | cites work | The EBV transforming protein, latent membrane protein 1, mimics and cooperates with CD40 signaling in B lymphocytes | Q74595824 |
T cell activation by TLRs: a role for TLRs in the adaptive immune response | Q81039397 | ||
Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling | Q22253441 | ||
CD40 AND CD154 IN CELL-MEDIATED IMMUNITY | Q22255634 | ||
Involvement of CRAF1, a relative of TRAF, in CD40 signaling | Q24306746 | ||
The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity | Q24310219 | ||
Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain | Q24604330 | ||
TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling | Q24634187 | ||
Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions | Q26853280 | ||
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2 | Q27639845 | ||
The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators | Q28198125 | ||
Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells | Q28205963 | ||
TNFR-associated factor-3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kappa B activation and IL-10 production | Q28216865 | ||
Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily | Q28239398 | ||
Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development | Q28265102 | ||
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor | Q28282051 | ||
TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1 | Q28361340 | ||
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1 | Q57198201 | ||
Expression of the Cytoplasmic Tail of LMP1 in Mice Induces Hyperactivation of B Lymphocytes and Disordered Lymphoid Architecture | Q57791640 | ||
TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival | Q73925277 | ||
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region | Q28511583 | ||
Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling | Q28511980 | ||
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling | Q28513445 | ||
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation | Q28584897 | ||
Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death | Q28609905 | ||
CD40 regulates the processing of NF-kappaB2 p100 to p52 | Q28610678 | ||
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 | Q28610812 | ||
IL-15 regulates homeostasis and terminal maturation of NKT cells | Q28741430 | ||
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice | Q29618716 | ||
Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression | Q33784729 | ||
Interaction of tumor necrosis factor receptor-associated factor signaling proteins with the latent membrane protein 1 PXQXT motif is essential for induction of epidermal growth factor receptor expression | Q33786551 | ||
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs | Q33864629 | ||
TRAF3 regulates homeostasis of CD8+ central memory T cells. | Q33882681 | ||
Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor | Q33888498 | ||
The TRAF3 adaptor protein drives proliferation of anaplastic large cell lymphoma cells by regulating multiple signaling pathways | Q33953115 | ||
The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2. | Q34071164 | ||
B lymphocyte activation by contact-mediated interactions with T lymphocytes. | Q34282293 | ||
Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling | Q34340648 | ||
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. | Q34340672 | ||
Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling | Q34580224 | ||
TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling | Q34603380 | ||
Myeloid cell TRAF3 regulates immune responses and inhibits inflammation and tumor development in mice. | Q34749424 | ||
Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production | Q34819672 | ||
The CD40-CD154 interaction in B cell-T cell liaisons | Q35145640 | ||
CD40-mediated maintenance of immune homeostasis in the adipose tissue microenvironment. | Q35360534 | ||
Antigen-specific B-lymphocyte activation. | Q35570847 | ||
Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes | Q35609384 | ||
Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival. | Q35917481 | ||
Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs | Q36156167 | ||
Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice. | Q36208548 | ||
TRAF3: a novel tumor suppressor gene in macrophages. | Q36357661 | ||
Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). | Q36369236 | ||
Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes | Q36403897 | ||
The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development. | Q36485370 | ||
Nuclear TRAF3 is a negative regulator of CREB in B cells | Q36551524 | ||
Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation | Q36564433 | ||
A novel polymorphism of the human CD40 receptor with enhanced function | Q36843735 | ||
Control points in NKT-cell development | Q36858868 | ||
TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells | Q36907898 | ||
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. | Q37178911 | ||
TRAF3 regulates the effector function of regulatory T cells and humoral immune responses | Q37483143 | ||
Functional roles for T cell CD40 in infection and autoimmune disease: the role of CD40 in lymphocyte homeostasis. | Q37524800 | ||
Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1. | Q37781398 | ||
Expanding TRAF function: TRAF3 as a tri-faced immune regulator | Q37887494 | ||
The seventh ring: exploring TRAF7 functions. | Q37959350 | ||
T cell receptor signalling networks: branched, diversified and bounded | Q38092568 | ||
Latent membrane protein 1 and the B lymphocyte-a complex relationship. | Q38221181 | ||
TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. | Q38293065 | ||
Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation | Q38294592 | ||
TRAF3, ubiquitination, and B-lymphocyte regulation. | Q38530616 | ||
Spatiotemporal pattern of TRAF3 expression after rat spinal cord injury | Q38997693 | ||
Activation-induced tumor necrosis factor receptor-associated factor 3 (Traf3) alternative splicing controls the noncanonical nuclear factor κB pathway and chemokine expression in human T cells | Q39011442 | ||
A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes | Q39037203 | ||
TRAF5 negatively regulates TLR signaling in B lymphocytes | Q39060065 | ||
Consequences of the direct interaction of helper T cells with B cells presenting antigen | Q39483731 | ||
Activated human neonatal CD8+ T cells are subject to immunomodulation by direct TLR2 or TLR5 stimulation. | Q40015976 | ||
A novel mechanism for TNFR-associated factor 6-dependent CD40 signaling | Q40078976 | ||
Cooperation between TNF receptor-associated factors 1 and 2 in CD40 signaling. | Q40290683 | ||
Differential regulation of CD40-mediated TNF receptor-associated factor degradation in B lymphocytes. | Q40376295 | ||
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation | Q40566781 | ||
Role of TNF receptor-associated factor 3 in the CD40 signaling by production of reactive oxygen species through association with p40phox, a cytosolic subunit of nicotinamide adenine dinucleotide phosphate oxidase | Q40605243 | ||
Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction. | Q40716536 | ||
Regulation of TRAF2 signaling by self-induced degradation. | Q40742977 | ||
TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis. | Q40933796 | ||
Cutting edge: contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation | Q40951300 | ||
A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. | Q41352964 | ||
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling | Q43142702 | ||
Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response | Q44233229 | ||
Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling. | Q45054574 | ||
LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3. | Q45436282 | ||
Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses | Q45746898 | ||
NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation | Q46195385 | ||
An intact zinc ring finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-kappaB activation but is dispensable for c-Jun N-terminal kinase signaling | Q46630234 | ||
TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation. | Q50792035 | ||
TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function. | Q50999206 | ||
TLR2 engagement on CD8 T cells enables generation of functional memory cells in response to a suboptimal TCR signal. | Q51833450 | ||
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. | Q52522634 | ||
Complete structural characterisation of the mammalian and Drosophila TRAF genes: implications for TRAF evolution and the role of RING finger splice variants. | Q52587074 | ||
P433 | issue | 5 | |
P304 | page(s) | 919-926 | |
P577 | publication date | 2016-05-06 | |
P1433 | published in | Journal of Leukocyte Biology | Q1524048 |
P1476 | title | TRAF3 as a powerful and multitalented regulator of lymphocyte functions | |
P478 | volume | 100 |
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Q64990463 | Regulation of Interleukin-6 Receptor Signaling by TNF Receptor-Associated Factor 2 and 5 During Differentiation of Inflammatory CD4+ T Cells. |
Q93053015 | TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis |
Q52661592 | TRAF molecules in inflammation and inflammatory diseases. |
Q57810578 | TRAF2 Deficiency in B Cells Impairs CD40-Induced Isotype Switching That Can Be Rescued by Restoring NF-κB1 Activation |
Q57492396 | TRAF3 as a Multifaceted Regulator of B Lymphocyte Survival and Activation |
Q90002815 | TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells |
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