scholarly article | Q13442814 |
P50 | author | Yonatan Dollin | Q86554816 |
Jing H Wang | Q86554818 | ||
Rachel Woolaver | Q91302219 | ||
Zhangguo Chen | Q92426171 | ||
P2093 | author name string | Ping Xie | |
Xiaoguang Wang | |||
P2860 | cites work | Essential function for the kinase TAK1 in innate and adaptive immune responses | Q50335551 |
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. | Q52522634 | ||
CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome | Q55670500 | ||
CD40 ligand-transduced co-stimulation of T cells in the development of helper function | Q58882277 | ||
The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching | Q78298237 | ||
TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells | Q80991122 | ||
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 | ||
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway | Q24632504 | ||
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation | Q24645030 | ||
Regulation of Aicda expression and AID activity | Q26853622 | ||
IgH chain class switch recombination: mechanism and regulation | Q27001131 | ||
Tumor necrosis factor receptor-associated factors (TRAFs) | Q28199382 | ||
CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes | Q28216904 | ||
IgH class switching and translocations use a robust non-classical end-joining pathway | Q28241679 | ||
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair | Q28269740 | ||
Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling | Q28511980 | ||
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice | Q29618716 | ||
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. | Q33656097 | ||
Generation and repair of AID-initiated DNA lesions in B lymphocytes | Q33690522 | ||
Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1 | Q34364910 | ||
All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction | Q34543653 | ||
AID-initiated DNA lesions are differentially processed in distinct B cell populations | Q34550504 | ||
TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling | Q34603380 | ||
Mechanism and regulation of class switch recombination | Q34764888 | ||
Roles of the kinase TAK1 in CD40-mediated effects on vascular oxidative stress and neointima formation after vascular injury | Q35210912 | ||
Targeting TRAF3 Downstream Signaling Pathways in B cell Neoplasms | Q35575662 | ||
Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes | Q35609384 | ||
Constraints contributed by chromatin looping limit recombination targeting during Ig class switch recombination | Q35633829 | ||
CD40/CD154 interactions at the interface of tolerance and immunity | Q35698455 | ||
Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function. | Q35750832 | ||
Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs | Q36156167 | ||
Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-kappaB. | Q36229720 | ||
Three-dimensional architecture of the IgH locus facilitates class switch recombination | Q36235676 | ||
Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination. | Q36304948 | ||
CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions | Q36366592 | ||
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses | Q36400158 | ||
Immunoglobulin class-switch DNA recombination: induction, targeting and beyond | Q36534234 | ||
Molecular mechanisms of antibody somatic hypermutation. | Q36747477 | ||
Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells | Q36812431 | ||
TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40. | Q37291416 | ||
B cells that simultaneously express surface IgM and IgE in Nippostrongylus brasiliensis-infected SJA/9 mice do not provide evidence for isotype switching without gene deletion | Q37675351 | ||
Expanding TRAF function: TRAF3 as a tri-faced immune regulator | Q37887494 | ||
AID targeting in antibody diversity | Q37901614 | ||
The role of activation-induced deaminase in antibody diversification and genomic instability | Q38041514 | ||
Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks | Q38051860 | ||
TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. | Q38293065 | ||
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers | Q38348243 | ||
Cancer immunotherapy: activating innate and adaptive immunity through CD40 agonists. | Q38786054 | ||
TRAF3 as a powerful and multitalented regulator of lymphocyte functions. | Q38801811 | ||
Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma | Q39040982 | ||
Induction of an IgE response in mice by Nippostrongylus brasiliensis: characterization of lymphoid cells with intracytoplasmic or surface IgE. | Q39348498 | ||
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation | Q40566781 | ||
Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses | Q42488424 | ||
TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. | Q44217852 | ||
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling | Q44677754 | ||
Prospects for modulating the CD40/CD40L pathway in the therapy of the hyper-IgM syndrome. | Q45874408 | ||
NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation | Q46195385 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 3421-3430 | |
P577 | publication date | 2018-10-19 | |
P1433 | published in | Journal of Immunology | Q3521441 |
P1476 | title | TRAF2 Deficiency in B Cells Impairs CD40-Induced Isotype Switching That Can Be Rescued by Restoring NF-κB1 Activation | |
P478 | volume | 201 |
Q99594459 | Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study | cites work | P2860 |
Search more.