B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

scientific article published on 06 December 2009

B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.1829
P698PubMed publication ID19966806
P5875ResearchGate publication ID40453760

P50authorTasuku HonjoQ2395341
Sidonia FăgărășanQ89706927
P2093author name stringHitoshi Nagaoka
Mikiyo Nakata
Nasim A Begum
Reiko Shinkura
Keiichiro Suzuki
Thinh Huy Tran
P2860cites workActivation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)Q24290325
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationQ24645030
A composite C/EBP binding site is essential for the activity of the promoter of the IL-3/IL-5/granulocyte-macrophage colony-stimulating factor receptor beta c geneQ28142445
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switchingQ28366125
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cellsQ28509339
PipMaker--a web server for aligning two genomic DNA sequencesQ28776457
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequencesQ29547807
Sibling rivalry in the E2F familyQ29615056
The Sp-family of transcription factorsQ33778355
Molecular mechanisms of E2F-dependent activation and pRB-mediated repressionQ34318740
Molecular mechanism of class switch recombination: linkage with somatic hypermutationQ34542246
Mechanism and regulation of class switch recombinationQ34764888
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic miceQ35616311
rVista for comparative sequence-based discovery of functional transcription factor binding sitesQ35784206
T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cellsQ35955998
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptorsQ36151542
EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class SwitchingQ36222552
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangementsQ36229165
Regulation of AID expression in the immune responseQ36229307
Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-kappaB.Q36229720
The balance between Pax5 and Id2 activities is the key to AID gene expressionQ36371814
Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and ApoptosisQ36651856
Role of AID in tumorigenesisQ36845685
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor developmentQ36853393
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombinationQ37115233
Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenesQ37356991
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombinationQ37512400
Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cellsQ38302008
Specificity of nuclear protein binding to a CYP1A1 negative regulatory elementQ38363505
Negative regulation of CD4 gene expression by a HES-1-c-Myb complexQ39458972
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signalingQ40150411
Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) geneQ40400071
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.Q40587079
RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway.Q40807338
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.Q41233018
Myb binding sites within the N-ras promoter repress transcriptionQ42442216
Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutationQ42944652
Constitutive expression of AID leads to tumorigenesisQ42944928
E-proteins directly regulate expression of activation-induced deaminase in mature B cellsQ44419402
AID is required for c-myc/IgH chromosome translocations in vivoQ45021537
Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expressionQ46378599
AID is required for germinal center-derived lymphomagenesisQ46861217
Interferon-gamma-induced factor binding to the interleukin-4-responsive element of CD23b promoter in human tonsillar mononuclear cells: role in transient up-regulation of the interleukin-4-induced CD23b mRNA.Q50335892
Tissue-specific sensitivity to AID expression in transgenic mouse models.Q53344832
c-Myb repression of c-erbB-2 transcription by direct binding to the c-erbB-2 promoterQ72167828
IFN-gamma-dependent and -independent initiation of switch recombination by NK cellsQ74321449
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epitheliumQ80078384
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)148-154
P577publication date2009-12-06
P1433published inNature ImmunologyQ1071725
P1476titleB cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
P478volume11

Reverse relations

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