scholarly article | Q13442814 |
P50 | author | Tasuku Honjo | Q2395341 |
Sidonia Făgărășan | Q89706927 | ||
P2093 | author name string | Hitoshi Nagaoka | |
Mikiyo Nakata | |||
Nasim A Begum | |||
Reiko Shinkura | |||
Keiichiro Suzuki | |||
Thinh Huy Tran | |||
P2860 | cites work | Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 |
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation | Q24645030 | ||
A composite C/EBP binding site is essential for the activity of the promoter of the IL-3/IL-5/granulocyte-macrophage colony-stimulating factor receptor beta c gene | Q28142445 | ||
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching | Q28366125 | ||
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells | Q28509339 | ||
PipMaker--a web server for aligning two genomic DNA sequences | Q28776457 | ||
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences | Q29547807 | ||
Sibling rivalry in the E2F family | Q29615056 | ||
The Sp-family of transcription factors | Q33778355 | ||
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression | Q34318740 | ||
Molecular mechanism of class switch recombination: linkage with somatic hypermutation | Q34542246 | ||
Mechanism and regulation of class switch recombination | Q34764888 | ||
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice | Q35616311 | ||
rVista for comparative sequence-based discovery of functional transcription factor binding sites | Q35784206 | ||
T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells | Q35955998 | ||
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors | Q36151542 | ||
EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching | Q36222552 | ||
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements | Q36229165 | ||
Regulation of AID expression in the immune response | Q36229307 | ||
Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-kappaB. | Q36229720 | ||
The balance between Pax5 and Id2 activities is the key to AID gene expression | Q36371814 | ||
Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis | Q36651856 | ||
Role of AID in tumorigenesis | Q36845685 | ||
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development | Q36853393 | ||
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination | Q37115233 | ||
Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes | Q37356991 | ||
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination | Q37512400 | ||
Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells | Q38302008 | ||
Specificity of nuclear protein binding to a CYP1A1 negative regulatory element | Q38363505 | ||
Negative regulation of CD4 gene expression by a HES-1-c-Myb complex | Q39458972 | ||
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling | Q40150411 | ||
Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene | Q40400071 | ||
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. | Q40587079 | ||
RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway. | Q40807338 | ||
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells. | Q41233018 | ||
Myb binding sites within the N-ras promoter repress transcription | Q42442216 | ||
Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation | Q42944652 | ||
Constitutive expression of AID leads to tumorigenesis | Q42944928 | ||
E-proteins directly regulate expression of activation-induced deaminase in mature B cells | Q44419402 | ||
AID is required for c-myc/IgH chromosome translocations in vivo | Q45021537 | ||
Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression | Q46378599 | ||
AID is required for germinal center-derived lymphomagenesis | Q46861217 | ||
Interferon-gamma-induced factor binding to the interleukin-4-responsive element of CD23b promoter in human tonsillar mononuclear cells: role in transient up-regulation of the interleukin-4-induced CD23b mRNA. | Q50335892 | ||
Tissue-specific sensitivity to AID expression in transgenic mouse models. | Q53344832 | ||
c-Myb repression of c-erbB-2 transcription by direct binding to the c-erbB-2 promoter | Q72167828 | ||
IFN-gamma-dependent and -independent initiation of switch recombination by NK cells | Q74321449 | ||
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium | Q80078384 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 148-154 | |
P577 | publication date | 2009-12-06 | |
P1433 | published in | Nature Immunology | Q1071725 |
P1476 | title | B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers | |
P478 | volume | 11 |
Q35890025 | A Network Model to Describe the Terminal Differentiation of B Cells |
Q39924635 | A novel pax5-binding regulatory element in the igκ locus |
Q37288983 | A role for host activation-induced cytidine deaminase in innate immune defense against KSHV. |
Q34118000 | AID and somatic hypermutation. |
Q64086097 | AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma |
Q28265992 | AID targeting: old mysteries and new challenges |
Q33725435 | ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination. |
Q37351651 | Activation of Aicda gene transcription by Pax5 in plasmacytoma cells |
Q36592764 | Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers. |
Q24297331 | Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression |
Q28740775 | Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age |
Q37994933 | Activation-induced cytidine deaminase in antibody diversification and chromosome translocation |
Q42235285 | Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models |
Q38160778 | Age effects on mouse and human B cells |
Q35088890 | An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. |
Q43177792 | B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses |
Q91745234 | B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response |
Q33893517 | B cell TLRs and induction of immunoglobulin class-switch DNA recombination |
Q45257022 | B-cell agonists up-regulate AID and APOBEC3G deaminases, which induce IgA and IgG class antibodies and anti-viral function |
Q24632504 | BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway |
Q38712033 | Bach2 regulates AID-mediated immunoglobulin gene conversion and somatic hypermutation in DT40 B cells |
Q42171084 | Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch |
Q37634047 | Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination |
Q36316915 | Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications |
Q34958445 | Complex regulation and function of activation-induced cytidine deaminase |
Q34467437 | Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein IκB-ζ |
Q36316904 | CtIP promotes microhomology-mediated alternative end joining during class-switch recombination |
Q35826037 | Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity. |
Q35310199 | Dynamic changes in binding of immunoglobulin heavy chain 3' regulatory region to protein factors during class switching |
Q36455989 | E47 retroviral rescue of intrinsic B-cell defects in senescent mice. |
Q47758514 | Efficient Induction of Ig Gene Hypermutation in Ex Vivo-Activated Primary B Cells. |
Q37692338 | Extension of the germinal center stage of B cell development promotes autoantibodies in BXD2 mice |
Q38625372 | Fibrinogen-Related Proteins (FREPs) in Mollusks |
Q37776353 | Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis |
Q41193753 | Id3 Orchestrates Germinal Center B Cell Development. |
Q36534234 | Immunoglobulin class-switch DNA recombination: induction, targeting and beyond |
Q34684380 | In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression |
Q37323207 | Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A. |
Q37999121 | Inflammation-mediated genomic instability: roles of activation-induced cytidine deaminase in carcinogenesis |
Q36047693 | Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice. |
Q36033318 | Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination |
Q34170147 | Lysine residue at position 22 of the AID protein regulates its class switch activity. |
Q35988449 | MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals |
Q41400504 | Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli |
Q26829944 | Molecular programming of B cell memory |
Q26768663 | Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity |
Q57281736 | NKL homeobox gene activities in B-cell development and lymphomas |
Q38239866 | Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network |
Q37704005 | Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity |
Q34672702 | Production of thyrotropin receptor antibodies in acute phase of infectious mononucleosis due to Epstein-Barr virus primary infection: a case report of a child |
Q26853622 | Regulation of Aicda expression and AID activity |
Q34115234 | Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair |
Q41999588 | Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination |
Q34698277 | Role of activation-induced cytidine deaminase in the development of oral squamous cell carcinoma |
Q37835582 | Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus |
Q35585086 | Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells |
Q57810578 | TRAF2 Deficiency in B Cells Impairs CD40-Induced Isotype Switching That Can Be Rescued by Restoring NF-κB1 Activation |
Q37994927 | The AID dilemma: infection, or cancer? |
Q37549732 | The aryl hydrocarbon receptor controls cell-fate decisions in B cells. |
Q37212132 | Vitamin A and retinoic acid in the regulation of B-cell development and antibody production |
Q37677543 | Walking the AID tightrope |