scholarly article | Q13442814 |
P50 | author | David D. Chaplin | Q42780504 |
P2093 | author name string | Jun Li | |
William E Grizzle | |||
Qi Wu | |||
Hui-Chen Hsu | |||
John D Mountz | |||
John H Wang | |||
Tanja Guentert | |||
Cecil R Stockard | |||
Godwin Job | |||
Pingar Yang | |||
Thuc-Vy L Le | |||
P2860 | cites work | Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody | Q24817041 |
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells | Q28509339 | ||
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
Signals that initiate somatic hypermutation of B cells in vitro | Q31838852 | ||
The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation | Q33226024 | ||
Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis | Q33230561 | ||
Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease | Q33361951 | ||
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium | Q33399862 | ||
Marginal zone precursor B cells as cellular agents for type I IFN-promoted antigen transport in autoimmunity | Q33694922 | ||
B cell targeted therapies | Q33709315 | ||
IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16. | Q33767461 | ||
Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays | Q34160196 | ||
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis | Q34327451 | ||
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice | Q34729932 | ||
B cells as therapeutic targets for rheumatic diseases | Q35753658 | ||
AID: how does it aid antibody diversity? | Q35800376 | ||
Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial | Q35993027 | ||
Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice | Q36253581 | ||
AID in somatic hypermutation and class switch recombination | Q36389988 | ||
B cell targeted therapies in autoimmune diseases | Q36465513 | ||
Targeting of B cells in SLE: rationale and therapeutic opportunities | Q36661154 | ||
Peripheral B cell subsets | Q36867717 | ||
Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis | Q36908127 | ||
Anticytokine therapy impacting on B cells in autoimmune diseases | Q37433729 | ||
Walking the AID tightrope | Q37677543 | ||
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers | Q38348243 | ||
Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells | Q40739761 | ||
Critical role for mitochondria in B cell receptor-mediated apoptosis | Q40911390 | ||
Differentiation and apoptosis of human germinal center B-lymphocytes | Q41522446 | ||
Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathway | Q41903686 | ||
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection. | Q41949877 | ||
Safety and efficacy of rituximab in systemic lupus erythematosus: results from 136 patients from the French AutoImmunity and Rituximab registry | Q42661986 | ||
Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells | Q42743187 | ||
The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process | Q42944711 | ||
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies | Q44051064 | ||
Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora | Q44218058 | ||
Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis | Q44541019 | ||
Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis | Q44616885 | ||
Hyper-IgM syndrome with putative dominant negative mutation in activation-induced cytidine deaminase | Q44621269 | ||
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks | Q44774931 | ||
Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection | Q45880270 | ||
AID constrains germinal center size by rendering B cells susceptible to apoptosis. | Q45991820 | ||
Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis | Q46485635 | ||
Control of idiotope expression by monoclonal anti-idiotope and idiotope-bearing antibody | Q52225605 | ||
Genetic Segregation of Spontaneous Erosive Arthritis and Generalized Autoimmune Disease in the BXD2 Recombinant Inbred Strain of Mice | Q57982623 | ||
Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis | Q61628467 | ||
Somatic mutation of immunoglobulin V genes in vitro | Q71095985 | ||
Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus | Q79171865 | ||
Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis | Q81248173 | ||
Blockade of lymphotoxin pathway exacerbates autoimmune arthritis by enhancing the Th1 response | Q81300642 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 7 | |
P304 | page(s) | 2038-2048 | |
P577 | publication date | 2011-07-01 | |
P1433 | published in | Arthritis and Rheumatism | Q23929027 |
P1476 | title | Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice | |
P478 | volume | 63 |
Q41684084 | Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes |
Q38017761 | Activation induced deaminase: How much and where? |
Q83390734 | Activation-induced cytidine deaminase catalytic domain as a target to eliminate pathogenic autoantibodies |
Q28507678 | Altered Pattern of Immunoglobulin Hypermutation in Mice Deficient in Slip-GC Protein |
Q48343851 | Association Between Serum MicroRNAs and Magnetic Resonance Imaging Measures of Multiple Sclerosis Severity |
Q83860003 | Autoimmunity: Engineered AICDA balances B cells |
Q40773152 | Cutting Edge: defective follicular exclusion of apoptotic antigens due to marginal zone macrophage defects in autoimmune BXD2 mice. |
Q37714326 | Death Receptor 5–Targeted Depletion of Interleukin‐23–Producing Macrophages, Th17, and Th1/17 Associated With Defective Tyrosine Phosphatase in Mice and Patients With Rheumatoid Arthritis |
Q37846094 | Epigenetic alterations in autoimmune rheumatic diseases |
Q37692338 | Extension of the Germinal Center Stage of B Cell Development Promotes Autoantibodies in BXD2 Mice |
Q35562921 | General Approach for Tetramer-Based Identification of Autoantigen-Reactive B Cells: Characterization of La- and snRNP-Reactive B Cells in Autoimmune BXD2 Mice |
Q37284814 | IL-17RA Is Essential for Optimal Localization of Follicular Th Cells in the Germinal Center Light Zone To Promote Autoantibody-Producing B Cells |
Q34060009 | IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and RORγt |
Q36040281 | Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus |
Q34098180 | Interleukin-21 promotes germinal center reaction by skewing the follicular regulatory T cell to follicular helper T cell balance in autoimmune BXD2 mice |
Q36033318 | Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination |
Q26853622 | Regulation of Aicda expression and AID activity |
Q35175080 | Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells |
Q42438365 | Separation of Function between Isotype Switching and Affinity Maturation In Vivo during Acute Immune Responses and Circulating Autoantibodies in UNG-Deficient Mice |
Q41183432 | Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model |
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