| scholarly article | Q13442814 |
| P50 | author | Tasuku Honjo | Q2395341 |
| P2093 | author name string | Reiko Shinkura | |
| Henry H Wortis | |||
| John F Kearney | |||
| Monika Pilichowska | |||
| Thereza Imanishi-Kari | |||
| Erik Selsing | |||
| Carlos O Medina | |||
| Gabrielle McDonald | |||
| P2860 | cites work | The role of clonal selection and somatic mutation in autoimmunity | Q59082893 |
| Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes | Q59098044 | ||
| Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney | Q69737615 | ||
| Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing | Q71457193 | ||
| SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis | Q77994482 | ||
| Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus | Q79834758 | ||
| Decrease in pregnancy loss rates in patients with systemic lupus erythematosus over a 40-year period | Q81162732 | ||
| A Systematic Review and Meta-Analysis of Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus and Lupus Nephritis | Q22305768 | ||
| BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway | Q24632504 | ||
| Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells | Q28509339 | ||
| Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
| Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors | Q29615065 | ||
| Predominant autoantibody production by early human B cell precursors | Q29619656 | ||
| Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus | Q30485404 | ||
| Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency | Q33359560 | ||
| Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease | Q33361951 | ||
| Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus | Q33637487 | ||
| Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity. | Q33835200 | ||
| Revising B cell receptors | Q33935117 | ||
| Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity | Q34161517 | ||
| Selection events operating at various stages in B cell development | Q34167959 | ||
| Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE. | Q34339372 | ||
| Negative regulation of activation-induced cytidine deaminase in B cells | Q34479651 | ||
| Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. | Q34566135 | ||
| CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans | Q34651496 | ||
| Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis | Q34816243 | ||
| Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans | Q35105055 | ||
| Activation-induced cytidine deaminase mediates central tolerance in B cells | Q35105238 | ||
| Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A). | Q35546818 | ||
| Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination. | Q35627706 | ||
| REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase | Q35669089 | ||
| Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE. | Q35821347 | ||
| In vivo evidence for apoptosis in the bone marrow in systemic lupus erythematosus | Q35953561 | ||
| T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells | Q35955998 | ||
| Female mouse fetal loss mediated by maternal autoantibody | Q36021796 | ||
| Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination | Q36033318 | ||
| Female Bias in Systemic Lupus Erythematosus is Associated with the Differential Expression of X-Linked Toll-Like Receptor 8 | Q36033680 | ||
| Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice. | Q36047693 | ||
| Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors | Q36151542 | ||
| Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors | Q36229232 | ||
| IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta | Q36229267 | ||
| Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice | Q36253581 | ||
| Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance | Q36304376 | ||
| Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice | Q36375280 | ||
| Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus | Q36403146 | ||
| RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. | Q36403678 | ||
| Impact of in utero environment on the offspring of lupus patients | Q36677036 | ||
| Proteasomal degradation restricts the nuclear lifespan of AID | Q36699771 | ||
| The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies | Q36850723 | ||
| Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization. | Q37047327 | ||
| Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells | Q37322190 | ||
| Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny | Q37345832 | ||
| Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint | Q37395827 | ||
| Expression of an anti-RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN-I expression | Q37625812 | ||
| Checkpoints in lymphocyte development and autoimmune disease | Q37657051 | ||
| BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance | Q37669385 | ||
| Intracellular toll-like receptors | Q37719951 | ||
| Properties of mouse and human IgG receptors and their contribution to disease models | Q38005653 | ||
| DNA-reactive B cells in lupus | Q38922669 | ||
| A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines | Q39683818 | ||
| Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice | Q40231922 | ||
| Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. | Q41423746 | ||
| Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense | Q41430473 | ||
| V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies | Q41824649 | ||
| A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus | Q43786936 | ||
| T cell-independent somatic hypermutation in murine B cells with an immature phenotype | Q44771096 | ||
| AID constrains germinal center size by rendering B cells susceptible to apoptosis. | Q45991820 | ||
| Toll-like receptor 9 signaling protects against murine lupus | Q46872996 | ||
| Structural bases of Fc gamma R functions | Q47889812 | ||
| Effects of Mothers' Autoimmune Disease During Pregnancy on Learning Disabilities and Hand Preference in Their Children | Q47974068 | ||
| Contribution of Vh gene replacement to the primary B cell repertoire | Q48236158 | ||
| The influence of systemic lupus erythematosus on fetal development: cognitive, behavioral, and health trends. | Q48665652 | ||
| Clinical significance of anti-dsDNA antibody isotypes: IgG/IgM ratio of anti-dsDNA antibodies as a prognostic marker for lupus nephritis. | Q51053168 | ||
| Neuropsychological development of children born to patients with systemic lupus erythematosus. | Q52085774 | ||
| Systemic lupus erythematosus: learning disability in the male offspring of female patients and relationship to laterality. | Q52253625 | ||
| Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. | Q52529090 | ||
| Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. | Q54664586 | ||
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 15 | |
| P304 | page(s) | 1094 | |
| P577 | publication date | 2017-09-13 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P4032 | reviewed by | Paolo Casali | Q55313435 |
| P1476 | title | Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes | |
| P478 | volume | 8 |
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