scholarly article | Q13442814 |
P356 | DOI | 10.1084/JEM.190.5.691 |
P8608 | Fatcat ID | release_nse5e5ipgfahfanuiwabaqhv3m |
P932 | PMC publication ID | 2195620 |
P698 | PubMed publication ID | 10477553 |
P5875 | ResearchGate publication ID | 12821678 |
P2093 | author name string | S Litwin | |
M Weigert | |||
E L Prak | |||
F Brard | |||
M Shannon | |||
P2860 | cites work | Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes | Q24652779 |
The Fas death factor | Q29620461 | ||
Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras | Q34313426 | ||
Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda | Q35331370 | ||
V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling | Q35911221 | ||
Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice | Q36231704 | ||
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation | Q36350233 | ||
Receptor editing: an approach by autoreactive B cells to escape tolerance | Q36361497 | ||
Receptor editing in self-reactive bone marrow B cells | Q36361578 | ||
B lymphocytes may escape tolerance by revising their antigen receptors | Q36361618 | ||
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes | Q36363024 | ||
Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance | Q36364008 | ||
Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus | Q36364520 | ||
Immunoglobulin chain loss in hybridoma lines | Q36364766 | ||
Light chain replacement: a new model for antibody gene rearrangement | Q36365220 | ||
Regulation of anti-DNA B cells in recombination-activating gene-deficient mice | Q36401575 | ||
Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes | Q36404207 | ||
Antinuclear antibodies: diagnostic markers and clues to the basis of systemic autoimmunity | Q38190657 | ||
A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage | Q38349361 | ||
Genetic and structural evidence for antigen selection of anti-DNA antibodies. | Q40661152 | ||
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens | Q41170875 | ||
The lupus autoantigens and the pathogenesis of systemic lupus erythematosus | Q41355812 | ||
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. | Q41423746 | ||
Ig H and L chain contributions to autoimmune specificities | Q42623521 | ||
Residues that mediate DNA binding of autoimmune antibodies | Q42799912 | ||
Variable region genes of anti-histone autoantibodies from a MRL/Mp-lpr/lpr mouse | Q42800186 | ||
Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis | Q43586184 | ||
Linked sets of antinuclear antibodies: what do they mean? | Q44218886 | ||
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells | Q45971909 | ||
DNA-binding antibodies from viable motheaten mutant mice: implications for B cell tolerance | Q48045089 | ||
Light chain contribution to specificity in anti-DNA antibodies | Q48070592 | ||
B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice. | Q48074053 | ||
The mechanism of autoantibody production in an autoimmune MRL/lpr mouse. | Q48077827 | ||
V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice | Q48132884 | ||
A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. | Q52039800 | ||
Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. | Q54177718 | ||
Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice | Q59065295 | ||
The role of clonal selection and somatic mutation in autoimmunity | Q59082893 | ||
Oligoclonality of rheumatoid factors arising spontaneously in lpr/lpr mice | Q68256179 | ||
Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription | Q69230362 | ||
Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes | Q71197127 | ||
Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing | Q71457193 | ||
Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells | Q71854871 | ||
Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells | Q71854877 | ||
Effects of the lpr mutation on elimination and inactivation of self-reactive B cells | Q72166872 | ||
Editing disease-associated autoantibodies | Q73115270 | ||
Characterization of B cells expressing recombination activating genes in germinal centers of immunized mouse lymph nodes | Q73128594 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 691-704 | |
P577 | publication date | 1999-09-01 | |
P1433 | published in | Journal of Experimental Medicine | Q3186912 |
P1476 | title | Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice | |
P478 | volume | 190 |
Q42945090 | A Fail-safe Mechanism for Negative Selection of Isotype-switched B Cell Precursors Is Regulated by the Fas/FasL Pathway |
Q36253581 | Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice |
Q41684084 | Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes |
Q36376630 | Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern |
Q35084274 | Antigen receptor selection by editing or downregulation of V(D)J recombination. |
Q36404580 | Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice |
Q35106998 | Autoantibodies: Focus on anti-DNA antibodies |
Q36375253 | Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice |
Q80123338 | Autoreactive B cells get activated in extrafollicular sites |
Q27692084 | B cell receptor editing in tolerance and autoimmunity |
Q40193479 | C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice |
Q74268401 | Circulating human B cells that express surrogate light chains and edited receptors |
Q36594883 | Competence and competition: the challenge of becoming a long-lived plasma cell |
Q38170793 | Contributions of B cells to lupus pathogenesis |
Q38302173 | CpG DNA stimulates autoreactive immature B cells in the bone marrow |
Q36811047 | Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. |
Q42103357 | Diversification of the Ig variable region gene repertoire of synovial B lymphocytes by nucleotide insertion and deletion |
Q37469579 | Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir. |
Q36499182 | Editing and escape from editing in anti-DNA B cells |
Q43832072 | Editors and editing of anti-DNA receptors. |
Q36399625 | Evidence for selective transformation of autoreactive immature plasma cells in mice deficient in Fasl |
Q36547706 | Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity |
Q37260869 | Human B cell subsets |
Q34295087 | Ig heavy-chain gene revision: leaping towards autoimmunity |
Q36368599 | Immunization and infection change the number of recombination activating gene (RAG)-expressing B cells in the periphery by altering immature lymphocyte production |
Q30942899 | Immunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytes |
Q42616049 | Indications for peripheral light-chain revision and somatic hypermutation without a functional B-cell receptor in precursors of a composite diffuse large B-cell and Hodgkin's lymphoma |
Q36228717 | Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction. |
Q34275985 | Pathogenesis of rheumatoid arthritis. Role of B lymphocytes |
Q33432528 | Patterns of receptor revision in the immunoglobulin heavy chains of a teleost fish |
Q54580372 | Peripheral B cell receptor editing may promote the production of high-affinity autoantibodies in CD22-deficient mice. |
Q35821347 | Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE. |
Q34613910 | Receptor revision and systemic lupus. |
Q33904476 | Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes |
Q52015874 | Receptor revision plays no major role in shaping the receptor repertoire of human memory B cells after the onset of somatic hypermutation. |
Q47927263 | Recombination activating genes (RAG) induce secondary Ig gene rearrangement in and subsequent apoptosis of human peripheral blood circulating B lymphocytes |
Q37134291 | Regulation of B cell tolerance by 129-derived chromosome 1 loci in C57BL/6 mice |
Q44321091 | Regulation of anti-phosphatidylserine antibodies |
Q33935117 | Revising B cell receptors |
Q53912452 | Role of Complement-Binding CD21/CD19/CD81 in Enhancing Human B Cell Protection from Fas-Mediated Apoptosis |
Q36370474 | Secondary heavy chain rearrangement: a mechanism for generating anti-double-stranded DNA B cells |
Q27024166 | Secondary receptor editing in the generation of autoimmunity |
Q37387660 | Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance |
Q35690880 | Similarities and differences between the light and heavy chain Ig variable region gene repertoires in chronic lymphocytic leukemia. |
Q34161517 | Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity |
Q26860815 | Somatic mutagenesis in autoimmunity |
Q30435791 | Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3. |
Q33950104 | Structural basis for autoantibody recognition of phosphatidylserine-beta 2 glycoprotein I and apoptotic cells |
Q36216540 | Structure-function analysis of a lupus anti-DNA autoantibody: central role of the heavy chain complementarity-determining region 3 Arg in binding of double- and single-stranded DNA. |
Q34242639 | Studies of the humoral immune response |
Q44771096 | T cell-independent somatic hypermutation in murine B cells with an immature phenotype |
Q26801600 | The analysis of clonal expansions in normal and autoimmune B cell repertoires |
Q36402023 | The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies |
Q33878890 | The evolution of human anti-double-stranded DNA autoantibodies |
Q34056955 | The role of rearrangement at the second Ig heavy chain locus in maintaining B cell tolerance to DNA. |
Q41956989 | Time between onset of apoptosis and release of nucleosomes from apoptotic cells: putative implications for systemic lupus erythematosus. |
Q40646599 | Transcript expression of two Iglambda rearrangements and RAG-1/RAG-2 in a mature human B cell producing IgMlambda islet cell autoantibody. |
Q48871229 | Transcription factor Gfi1 restricts B cell-mediated autoimmunity |
Q35045906 | Transgenic models of tolerance and autoimmunity: with special reference to systemic lupus erythematosus |
Q38187652 | Trials and Tribulations with VH Replacement |
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