Efficient Induction of Ig Gene Hypermutation in Ex Vivo-Activated Primary B Cells.

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Efficient Induction of Ig Gene Hypermutation in Ex Vivo-Activated Primary B Cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1700868
P698PubMed publication ID28939756

P50authorTakeshi TsubataQ59680175
P2093author name stringJun Liu
Kazuo Kinoshita
Ji-Yang Wang
Hiromi Mori
Ermeng Xiong
Hanying Zhu
Shoya Yasuda
P2860cites workMicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocationQ24646923
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminaseQ24653222
Mutations, kataegis and translocations in B cells: understanding AID promiscuous activityQ26768663
Regulation of Aicda expression and AID activityQ26853622
IL-10 regulates Aicda expression through miR-155Q28251207
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNAQ28512692
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
Potential roles of activation-induced cytidine deaminase in promotion or prevention of autoimmunity in humansQ33829729
Binding of AID to DNA does not correlate with mutator activityQ33833373
AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes.Q34037321
Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cellsQ34375128
Negative regulation of activation-induced cytidine deaminase in B cellsQ34479651
Mechanism and regulation of class switch recombinationQ34764888
Balancing AID and DNA repair during somatic hypermutationQ34966633
Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humansQ35105055
Activation-induced cytidine deaminase mediates central tolerance in B cellsQ35105238
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.Q35289306
Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylationQ36519034
Molecular mechanisms of antibody somatic hypermutation.Q36747477
Activation-induced cytidine deaminase (AID) is necessary for the epithelial-mesenchymal transition in mammary epithelial cells.Q37088708
The cell cycle restricts activation-induced cytidine deaminase activity to early G1.Q37549772
Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesisQ37776353
Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidneyQ38291974
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencersQ38348243
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody GenesQ38388195
Plasmodium chabaudi infection induces AID expression in transitional and marginal zone B cellsQ39096599
Induction of a:T mutations is dependent on cellular environment but independent of mutation frequency and target gene locationQ39914923
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.Q41233018
Active nuclear import and cytoplasmic retention of activation-induced deaminaseQ41792388
Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutationQ42944652
Constitutive expression of AID leads to tumorigenesisQ42944928
Role of antigen receptor affinity in T cell-independent antibody responses in vivoQ43918933
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)3023-3030
P577publication date2017-09-22
P1433published inJournal of ImmunologyQ3521441
P1476titleEfficient Induction of Ig Gene Hypermutation in Ex Vivo-Activated Primary B Cells
P478volume199

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cites work (P2860)
Q92282130MZB1 promotes the secretion of J-chain-containing dimeric IgA and is critical for the suppression of gut inflammation
Q92471896The B cell novel protein 1 (BCNP1) regulates BCR signaling and B cell apoptosis

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