scholarly article | Q13442814 |
P50 | author | Shigeru Kondo | Q55404878 |
P2093 | author name string | M Nakamura | |
T Honjo | |||
M Nazarea | |||
S Imamura | |||
M Sugai | |||
P4510 | describes a project that uses | CH12F3 | Q54811615 |
P433 | issue | 2 | |
P921 | main subject | cell line | Q21014462 |
P304 | page(s) | 193-201 | |
P577 | publication date | 1996-02-01 | |
P1433 | published in | International Immunology | Q15710043 |
P1476 | title | High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells | |
P478 | volume | 8 |
Q39664674 | 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. |
Q92477502 | 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function |
Q42180821 | A T cell-dependent mechanism for the induction of human mucosal homing immunoglobulin A-secreting plasmablasts |
Q33947941 | A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs |
Q46694387 | A memoir of AID, which engraves antibody memory on DNA. |
Q92432643 | A novel regulatory region controls IgH locus transcription and switch recombination to a subset of isotypes |
Q35068183 | AID to overcome the limitations of genomic information by introducing somatic DNA alterations |
Q37045143 | APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells. |
Q37351651 | Activation of Aicda gene transcription by Pax5 in plasmacytoma cells |
Q34357060 | Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5 |
Q35119869 | Activation‐Induced Cytidine Deaminase Links Class Switch Recombination and Somatic Hypermutation |
Q39918892 | Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells |
Q36714911 | Alum Directly Modulates Murine B Lymphocytes to Produce IgG1 Isotype |
Q38707002 | An efficient method to enrich for knock-out and knock-in cellular clones using the CRISPR/Cas9 system. |
Q39434592 | Asbestos activates CH12.LX B-lymphocytes via macrophage signaling |
Q39443203 | Assessing somatic hypermutation in Ramos B cells after overexpression or knockdown of specific genes |
Q38348243 | B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers |
Q33833373 | Binding of AID to DNA does not correlate with mutator activity |
Q41060120 | CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line. |
Q36349107 | CSReport: A New Computational Tool Designed for Automatic Analysis of Class Switch Recombination Junctions Sequenced by High-Throughput Sequencing |
Q37115229 | Carboxy-terminal domain of AID required for its mRNA complex formation in vivo |
Q42541714 | Checkpoint kinase 2 is required for efficient immunoglobulin diversification |
Q50020989 | Chemotherapy-induced differential cell cycle arrest in B cell lymphomas affects their sensitivity to Wee1 inhibition |
Q38982117 | Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining |
Q29547201 | Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme |
Q35004467 | Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survival |
Q39480949 | Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells |
Q35609131 | Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids |
Q33792418 | Could the airway epithelium play an important role in mucosal immunoglobulin A production? |
Q50133428 | DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions. |
Q64077615 | DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells |
Q37512400 | De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination |
Q47404983 | Depletion of recombination-specific cofactors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination |
Q36845653 | Discovery of activation-induced cytidine deaminase, the engraver of antibody memory |
Q47758514 | Efficient Induction of Ig Gene Hypermutation in Ex Vivo-Activated Primary B Cells. |
Q91768057 | Essential role of the initial activation signal in isotype selection upon deletion of a transcriptionally committed promoter |
Q36368414 | Evidence for class-specific factors in immunoglobulin isotype switching |
Q40570603 | Expression of activation-induced cytidine deaminase (AID) in Burkitt lymphoma cells: rare AID-negative cell lines with the unmutated rearranged VH gene |
Q41058525 | Frequent but biased class switch recombination in the S mu flanking regions. |
Q36710679 | Functional requirements of AID's higher order structures and their interaction with RNA-binding proteins |
Q91013779 | Fundamental roles of chromatin loop extrusion in antibody class switching |
Q33631933 | Further Characterization of Activin A-induced IgA Response in Murine B Lymphocytes |
Q35143768 | Generation and characterization of induced pluripotent stem cells from Aid-deficient mice |
Q24299046 | Genome instability and transcription elongation impairment in human cells depleted of THO/TREX |
Q35280881 | Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development |
Q48268350 | Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination. |
Q34438355 | Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination |
Q34929551 | IL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches |
Q40900090 | Identification of a stimulus-dependent DNase I hypersensitive site between the Ialpha and Calpha exons during immunoglobulin heavy chain class switch recombination |
Q47661716 | IgH isotype-specific B cell receptor expression influences B cell fate |
Q36304948 | Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination. |
Q43776134 | In situ class switching and differentiation to IgA-producing cells in the gut lamina propria |
Q34614189 | Innate signaling networks in mucosal IgA class switching |
Q37527174 | Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation. |
Q34168492 | Intestinal IgA synthesis: regulation of front-line body defences |
Q34656270 | Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase. |
Q60949741 | Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral IL-6 (vIL-6) Enhances Immunoglobulin Class-Switch Recombination |
Q41788723 | Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching |
Q36563447 | Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining |
Q34297090 | Linking class-switch recombination with somatic hypermutation |
Q39618298 | Macrophage-derived BAFF induces AID expression through the p38MAPK/CREB and JNK/AP-1 pathways |
Q34542246 | Molecular mechanism of class switch recombination: linkage with somatic hypermutation |
Q34162337 | Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis |
Q51041546 | Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry. |
Q24297481 | Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1 |
Q36116985 | Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching. |
Q35105143 | Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination |
Q37022423 | PARP activation promotes nuclear AID accumulation in lymphoma cells |
Q37281378 | PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line |
Q34249818 | PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells |
Q40815618 | Palindromic but not G-rich sequences are targets of class switch recombination |
Q37273095 | Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination |
Q57050164 | Parp3 promotes long-range end joining in murine cells |
Q47419320 | Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene |
Q36369428 | Quantitative regulation of class switch recombination by switch region transcription |
Q96135572 | REV7 is required for processing AID initiated DNA lesions in activated B cells |
Q55002369 | RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. |
Q36689901 | RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells |
Q34340626 | Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90. |
Q34115234 | Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair |
Q53839339 | Robust DNA repair in PAXX-deficient mammalian cells. |
Q58697513 | SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice |
Q34765637 | SUMO Proteins are not Involved in TGF-β1-induced, Smad3/4-mediated Germline α Transcription, but PIASy Suppresses it in CH12F3-2A B Cells |
Q28188341 | Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements |
Q59313925 | Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells |
Q35585086 | Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells |
Q47872719 | Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor |
Q35593692 | TGF-β suppression of HBV RNA through AID-dependent recruitment of an RNA exosome complex |
Q40982327 | Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions |
Q33226024 | The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation |
Q37994927 | The AID dilemma: infection, or cancer? |
Q42818062 | The AID enzyme induces class switch recombination in fibroblasts |
Q57191210 | The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination |
Q57787881 | The Common Key to Class-Switch Recombination and Somatic Hypermutation: Discovery of AID and Its Role in Antibody Gene Diversification |
Q34263084 | The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination |
Q52362335 | The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining. |
Q24337929 | The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates |
Q57091233 | The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes |
Q28592784 | The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination |
Q36955793 | The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation. |
Q24294424 | The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation |
Q28590053 | The histone methyltransferase MMSET regulates class switch recombination |
Q41389958 | The immunoglobulin class switch: beyond "accessibility". |
Q34708215 | The regulation of IgA class switching. |
Q59092404 | The shieldin complex mediates 53BP1-dependent DNA repair |
Q28512692 | The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA |
Q50351017 | Toll-like Receptor 1/2 Agonist Pam3CSK4 Suppresses Lipopolysaccharide-driven IgG1 Production while Enhancing IgG2a Production by B Cells |
Q52337496 | Trib1 Is Overexpressed in Systemic Lupus Erythematosus, While It Regulates Immunoglobulin Production in Murine B Cells. |
Q33860564 | Unique and unprecedented recombination mechanisms in class switching |
Q64058168 | Uracil–DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil |
Q33950143 | Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination |
Q34095055 | Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination |
Q64098587 | Will Attention by Vaccine Developers to the Host's Nuclear Hormone Levels and Immunocompetence Improve Vaccine Success? |
Q54811615 | CH12F3 | described by source | P1343 |
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