The histone methyltransferase MMSET regulates class switch recombination

scientific journal article

The histone methyltransferase MMSET regulates class switch recombination is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1201811
P932PMC publication ID3775478
P698PubMed publication ID23241889
P5875ResearchGate publication ID233930365

P50authorDiane F. JelinekQ110910982
P2093author name stringZhenkun Lou
Tongzheng Liu
Huadong Pei
Kefei Yu
Xiaosheng Wu
P2860cites workRegulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damageQ33733896
Selective induction of DNA repair pathways in human B cells activated by CD4+ T cellsQ33778759
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombinationQ33794964
Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.Q33818028
Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8Q33839896
Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancerQ33839938
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombinationQ34438355
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.Q34568855
Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversityQ34619789
Mechanism and regulation of class switch recombinationQ34764888
Wolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damageQ35164644
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programmingQ35569571
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutationQ36370913
ATM is required for efficient recombination between immunoglobulin switch regionsQ36399334
Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locusQ36427367
DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombinationQ36509842
53BP1 facilitates long-range DNA end-joining during V(D)J recombinationQ36682376
Molecular mechanisms of antibody somatic hypermutation.Q36747477
Evolution of the immunoglobulin heavy chain class switch recombination mechanismQ36845675
The biochemistry of somatic hypermutationQ37096080
Hijacked DNA repair proteins and unchained DNA polymerasesQ37140473
Multiple functions of MRN in end-joining pathways during isotype class switchingQ37291987
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressorQ40031496
Uracil DNA glycosylase activity is dispensable for immunoglobulin class switchQ40522938
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.Q41233018
Antibody deficiency in Wolf-Hirschhorn syndromeQ41926268
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.Q42271523
Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locusQ42799741
Delineation of the role of the Mre11 complex in class switch recombinationQ47237271
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myelomaQ24322575
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strandQ28190690
The etiology of Wolf-Hirschhorn syndromeQ28236976
IgH class switching and translocations use a robust non-classical end-joining pathwayQ28241679
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouseQ28289637
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sitesQ28304648
PTIP promotes chromatin changes critical for immunoglobulin class switch recombinationQ28585503
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombinationQ28592784
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndromeQ28593584
53BP1 is required for class switch recombinationQ29465541
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.Q29465548
BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination.Q30480499
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrateQ33553524
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectNuclear receptor binding SET domain protein 2Q21988839
Transformation related protein 53 binding protein 1Q21992210
P304page(s)756–763
P577publication date2013-01-15
P1433published inJournal of ImmunologyQ3521441
P1476titleThe histone methyltransferase MMSET regulates class switch recombination
P478volume190

Reverse relations

cites work (P2860)
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Q30574045Deletions involving genes WHSC1 and LETM1 may be necessary, but are not sufficient to cause Wolf-Hirschhorn Syndrome
Q33682993Differential effect of MMSET mRNA levels on survival to first-line FOLFOX and second-line docetaxel in gastric cancer
Q26781345Epigenetic Codes Programing Class Switch Recombination
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Q34622835HMGB1 in health and disease
Q48268350Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination.
Q34365204Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination
Q64389662L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
Q51358936MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents.
Q38180674Mind the methyl: methyllysine binding proteins in epigenetic regulation
Q35884525RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20
Q64389511Understanding the Histone DNA Repair Code: H4K20me2 Makes Its Mark
Q45868105Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development
Q61136635ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage