Activation of Aicda gene transcription by Pax5 in plasmacytoma cells

scientific article published on March 2013

Activation of Aicda gene transcription by Pax5 in plasmacytoma cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S12026-012-8357-8
P932PMC publication ID3844280
P698PubMed publication ID22956488

P2093author name stringJames Hagman
Carissa Dege
P2860cites workCommitment to the B-lymphoid lineage depends on the transcription factor Pax5Q22010683
Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho familyQ24594237
Reprogramming towards pluripotency requires AID-dependent DNA demethylationQ24607262
The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAPQ24630244
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationQ24645030
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogrammingQ28284694
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cellsQ28509339
The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cellsQ28593666
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocationsQ33588393
From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitmentQ33787798
Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemiaQ34168766
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.Q34249450
Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cellsQ34282966
Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation.Q34502653
Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.Q34740831
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytesQ35304991
Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).Q36119642
Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding proteinQ36227838
AID mediates hypermutation by deaminating single stranded DNA.Q36370366
The balance between Pax5 and Id2 activities is the key to AID gene expressionQ36371814
Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regionsQ36842394
The transcriptional regulation of B cell lineage commitment.Q36854605
The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes.Q36994216
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.Q37068711
The biochemistry of somatic hypermutationQ37096080
Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.Q37256859
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocationsQ37269390
Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancersQ37793964
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencersQ38348243
Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancerQ39679248
Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell developmentQ39974270
Episomal vectors to monitor and induce somatic hypermutation in human Burkitt-Lymphoma cell linesQ40347146
Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) geneQ40400071
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription.Q40516566
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.Q40587079
Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell lineQ40783328
C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.Q41064693
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.Q41233018
Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experimentsQ42642886
Activation-induced cytidine deaminase splicing patterns in chronic lymphocytic leukemiaQ43179782
E-proteins directly regulate expression of activation-induced deaminase in mature B cellsQ44419402
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signalingQ44677754
Different isoforms of BSAP regulate expression of AID in normal and chronic lymphocytic leukemia B cells.Q45161214
Two levels of protection for the B cell genome during somatic hypermutation.Q46755254
Molecular components of the B-cell antigen receptor complex of the IgM classQ50335807
Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.Q50943562
Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.Q52196159
Aberrant expression and mutation-inducing activity of AID in human lung cancer.Q54389595
Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoterQ71524910
Conveying the message: identification of Ig-alpha and Ig-beta as components of the B cell receptor complexQ84263103
P433issue1-3
P921main subjectplasmacytomaQ2090167
P304page(s)155-161
P577publication date2013-03-01
P1433published inImmunologic ResearchQ15754981
P1476titleActivation of Aicda gene transcription by Pax5 in plasmacytoma cells
P478volume55

Reverse relations

cites work (P2860)
Q92752637Diffuse large B-cell lymphoma carrying t(9;14)(p13;q32)/PAX5-immunoglobulin heavy chain gene is characterized by nuclear positivity of MUM1 and PAX5 by immunohistochemistry
Q91689074JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients
Q34115234Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair

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