E-proteins directly regulate expression of activation-induced deaminase in mature B cells

scientific article published on April 28, 2003

E-proteins directly regulate expression of activation-induced deaminase in mature B cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NI923
P953full work available at URLhttp://www.nature.com/articles/ni923.pdf
http://www.nature.com/articles/ni923
P698PubMed publication ID12717431
P5875ResearchGate publication ID10786006

P50authorCornelis MurreQ94947744
P2093author name stringYasutoshi Agata
Melanie W. Quong
Camil Elie Sayegh
P2860cites workActivation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)Q24290325
Promotion of cell cycle progression by basic helix-loop-helix E2AQ24291573
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteinsQ24299387
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequenceQ24300878
Histone-like TAFs within the PCAF histone acetylase complexQ24317520
Internal IgH class switch region deletions are position-independent and enhanced by AID expressionQ24535261
Helix-loop-helix proteins: regulators of transcription in eucaryotic organismsQ24554353
A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulationQ27936635
The ATM-related cofactor Tra1 is a component of the purified SAGA complexQ27937594
The CBP co-activator is a histone acetyltransferaseQ28131758
E protein function in lymphocyte developmentQ28203458
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversificationQ28208979
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression programQ28216493
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangementsQ28243194
The role of E-proteins in B- and T-lymphocyte developmentQ28273104
The helix-loop-helix gene E2A is required for B cell formationQ28504830
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cellsQ28509339
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animalsQ33985264
Molecular mechanism of class switch recombination: linkage with somatic hypermutationQ34542246
Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomasQ34945511
Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regionsQ34997657
Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locusQ35064395
E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteinsQ36686388
Impaired immune responses and B-cell proliferation in mice lacking the Id3 geneQ39447043
Increased transcription levels induce higher mutation rates in a hypermutating cell lineQ40814374
Cyclic re-entry of germinal center B cells and the efficiency of affinity maturationQ40858324
E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cellsQ40869804
Life and death in germinal centers (redux).Q40983825
The immunoglobulin class switch: beyond "accessibility".Q41389958
Shutdown of class switch recombination by deletion of a switch region control element.Q41573717
Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell lineQ41672433
A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complexQ41684988
E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombinationQ41702555
Histone acetylation determines the developmentally regulated accessibility for T cell receptor gamma gene recombinationQ41777608
Episomal vectors rapidly and stably produce high-titer recombinant retrovirusQ42810400
AID enzyme-induced hypermutation in an actively transcribed gene in fibroblastsQ42813803
The AID enzyme induces class switch recombination in fibroblastsQ42818062
Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutationQ42944652
Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3.Q42951830
Both E12 and E47 allow commitment to the B cell lineageQ45129651
Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locusQ47788471
Normal isotype switching in B cells lacking the I mu exon splice donor site: evidence for multiple I mu-like germline transcripts.Q52171631
Involvement of the E2A basic helix-loop-helix protein in immunoglobulin heavy chain class switchingQ71874702
Switch transcripts in immunoglobulin class switchingQ72635906
Ig S gamma-specific DNA binding protein SNAP is related to the helix-loop-helix transcription factor E47Q73544343
Transcription factors in lymphocyte development--T and B cells get togetherQ78170515
Essential role of Id2 in negative regulation of IgE class switchingQ78665388
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
P304page(s)586-593
P577publication date2003-04-28
P1433published inNature ImmunologyQ1071725
P1476titleE-proteins directly regulate expression of activation-induced deaminase in mature B cells
P478volume4

Reverse relations

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