A tamoxifen inducible knock-in allele for investigation of E2A function

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A tamoxifen inducible knock-in allele for investigation of E2A function is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1003030428
P356DOI10.1186/1471-213X-9-51
P8608Fatcat IDrelease_ekg6ry7ykncbfgzpk2vn6jcaau
P932PMC publication ID2765948
P698PubMed publication ID19822014

P2093author name stringYuan Zhuang
Motonari Kondo
Mary E Jones
P2860cites workFunctions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEBQ24290138
Promotion of cell cycle progression by basic helix-loop-helix E2AQ24291573
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequenceQ24300878
E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cellsQ24301680
Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotentQ24317920
Helix-loop-helix proteins: regulators of transcription in eucaryotic organismsQ24554353
Ligand-activated site-specific recombination in miceQ24600193
Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell developmentQ24645273
Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expressionQ28212702
Gradient of E2A activity in B-cell developmentQ28215170
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangementsQ28243194
Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-BQ28293931
Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivoQ28298865
The helix-loop-helix gene E2A is required for B cell formationQ28504830
Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouseQ29620355
Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascadeQ31929689
SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinationsQ33229588
Functional replacement of the mouse E2A gene with a human HEB cDNA.Q33773768
B cell development pathwaysQ34178187
Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesisQ34244368
Regulation of E2A gene expression in B-lymphocyte developmentQ34547316
Temporally and spatially regulated somatic mutagenesis in miceQ34659147
Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomasQ34945511
New insights into E-protein function in lymphocyte developmentQ36143437
Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcriptionQ36230026
Helix-loop-helix proteins and lymphocyte developmentQ36292892
Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47Q36375680
Important roles for E protein binding sites within the immunoglobulin kappa chain intronic enhancer in activating Vkappa Jkappa rearrangementQ36399353
Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2AQ36399448
Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2AQ36402675
E47 is required for V(D)J recombinase activity in common lymphoid progenitorsQ36403067
E2A promotes the survival of precursor and mature B lymphocytesQ36432006
Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytesQ36491701
E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expressionQ36491705
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.Q36560174
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell linesQ36700487
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factorQ36706855
Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophyQ36953163
E2A proteins promote development of lymphoid-primed multipotent progenitorsQ37010255
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitorsQ37100926
B-lineage differentiation in normal and transformed cells and the microenvironment that supports it.Q40661032
Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifenQ41574453
A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependentQ42724092
E-proteins directly regulate expression of activation-induced deaminase in mature B cellsQ44419402
Both E12 and E47 allow commitment to the B cell lineageQ45129651
Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell developmentQ57339980
Systematic design and testing of nested (RT-)PCR primers for specific amplification of mouse rearranged/expressed immunoglobulin variable region genes from small number of B cellsQ79623240
P921main subjecttamoxifenQ412178
P304page(s)51
P577publication date2009-10-12
P1433published inBMC Developmental BiologyQ15761839
P1476titleA tamoxifen inducible knock-in allele for investigation of E2A function
P478volume9

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cites work (P2860)
Q35117339Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.
Q90090969Depletion of ID3 enhances mesenchymal stem cells therapy by targeting BMP4 in Sjögren's syndrome
Q34708333Dynamic changes in E-protein activity regulate T reg cell development
Q30423667Genes that confer the identity of the renin cell
Q37572782Modeling Murine Gastric Metaplasia Through Tamoxifen-Induced Acute Parietal Cell Loss.
Q36300940Reversible modulation of SIRT1 activity in a mouse strain
Q51894293Stage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development.
Q59865561The Estrogen Receptor Fusion System in Mouse Models: A Reversible Switch