E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors

scholarly article

E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2009PNAS..106.1930S
P356DOI10.1073/PNAS.0808866106
P932PMC publication ID2644141
P698PubMed publication ID19181846
P5875ResearchGate publication ID23963763

P50authorIrving WeissmanQ884581
Cornelis MurreQ94947744
P2093author name stringElinore M Mercer
Matthew A Inlay
Craig L Semerad
P2860cites workHaematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 geneQ44286577
Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cellsQ45085155
Both E12 and E47 allow commitment to the B cell lineageQ45129651
Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cellsQ45227041
Stem cell repopulation efficiency but not pool size is governed by p27(kip1).Q45872224
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.Q46455047
Identification of clonogenic common lymphoid progenitors in mouse bone marrowQ46782262
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.Q50876705
GATA-1 Converts Lymphoid and Myelomonocytic Progenitors into the Megakaryocyte/Erythrocyte LineagesQ51017999
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.Q52214235
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacityQ64008447
Hematopoietic stem cell quiescence maintained by p21cip1/waf1Q73532192
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEBQ24290138
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteinsQ24299387
Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotentQ24317920
Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cellsQ24555063
Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cellsQ24603214
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1Q28295662
Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCLQ28508494
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic developmentQ28510978
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet developmentQ28591602
A clonogenic common myeloid progenitor that gives rise to all myeloid lineagesQ29615010
Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.Q31133190
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.Q33326050
Contingent gene regulatory networks and B cell fate specificationQ33935974
GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblastsQ34311278
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cellsQ34387030
Regulation of E2A gene expression in B-lymphocyte developmentQ34547316
Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage developmentQ34773120
Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cellsQ35611589
Transcriptional control of early B cell developmentQ35698401
Multitasking of helix-loop-helix proteins in lymphopoiesisQ35832501
New insights into E-protein function in lymphocyte developmentQ36143437
Helix-loop-helix proteins and lymphocyte developmentQ36292892
E47 is required for V(D)J recombinase activity in common lymphoid progenitorsQ36403067
Early hematopoietic lineage restrictions directed by Ikaros.Q37413012
E2A proteins enforce a proliferation checkpoint in developing thymocytesQ39315636
Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteinsQ40023533
GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcriptionQ40831774
Purification and characterization of mouse hematopoietic stem cellsQ42065991
Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3.Q42951830
P433issue6
P407language of work or nameEnglishQ1860
P1104number of pages6
P304page(s)1930-1935
P577publication date2009-01-30
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleE2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors
P478volume106

Reverse relations

cites work (P2860)
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