Molecular resolution of the B cell landscape

scientific article published on 12 January 2011

Molecular resolution of the B cell landscape is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.COI.2010.11.014
P932PMC publication ID3073704
P698PubMed publication ID21236654
P5875ResearchGate publication ID49757045

P2093author name stringLisa Borghesi
Patricia M Santos
P2860cites workSimple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesQ24617969
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitorsQ28254539
The helix-loop-helix gene E2A is required for B cell formationQ28504830
Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.Q43501853
Stem cell-specific epigenetic priming and B cell-specific transcriptional activation at the mouse Cd19 locusQ45223087
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.Q46455047
Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineagesQ46678691
Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells.Q50722197
Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.Q50749492
EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.Q50779847
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.Q50876705
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.Q50904250
Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.Q51991669
Regulation of B lymphocyte and macrophage development by graded expression of PU.1.Q55033922
Scl regulates the quiescence and the long-term competence of hematopoietic stem cellsQ28507644
Bcl11a is essential for normal lymphoid developmentQ28511014
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell developmentQ28513360
The Ikaros gene is required for the development of all lymphoid lineagesQ28594316
Foxo1 directly regulates the transcription of recombination-activating genes during B cell developmentQ33333434
Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progressionQ33842740
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitorsQ33889234
Some hematopoietic stem cells are more equal than othersQ33902371
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fateQ33961160
Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid developmentQ34122312
Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cellsQ34452440
Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitorsQ34686624
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenanceQ36007697
Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitorsQ36402594
E47 is required for V(D)J recombinase activity in common lymphoid progenitorsQ36403067
Epigenetic signatures of stem-cell identity.Q36761192
IRF8 regulates B-cell lineage specification, commitment, and differentiationQ36969752
E2A proteins promote development of lymphoid-primed multipotent progenitorsQ37010255
Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineageQ37062082
Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisionsQ37081977
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitorsQ37100926
Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiationQ37185858
Pertussis toxin-sensitive G proteins regulate lymphoid lineage specification in multipotent hematopoietic progenitorsQ37237437
Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.Q37256859
Cell-nonautonomous function of Id1 in the hematopoietic progenitor cell nicheQ37295138
Asynchronous RAG-1 expression during B lymphopoiesis.Q37484763
Hoxa9 Regulates Flt3 in Lymphohematopoietic ProgenitorsQ37535958
Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes.Q39693040
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitorsQ39926821
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.Q39970013
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphomaQ40337542
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitorsQ40747831
Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.Q40937465
Multilineage gene expression precedes commitment in the hemopoietic systemQ41120728
Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte developmentQ42140562
A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fatesQ42696841
Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatinQ42826918
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)163-170
P577publication date2011-01-12
P1433published inCurrent Opinion in ImmunologyQ15752917
P1476titleMolecular resolution of the B cell landscape
P478volume23

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cites work (P2860)
Q36478003A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network
Q41875376Cell-intrinsic in vivo requirement for the E47-p21 pathway in long-term hematopoietic stem cells
Q42154732Chromatin and transcriptional tango on the immune dance floor
Q34777511Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models
Q34773992E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction
Q37955518Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells
Q37085891High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia
Q50756735Immunophenotypic profile of nucleated erythroid progenitors during maturation in regenerating bone marrow.
Q27851839RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures
Q35011166The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells
Q37127364The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment
Q37895962Transcriptional and epigenetic regulation of B cell development
Q28082698ncRNA-regulated immune response and its role in inflammatory lung diseases

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