E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors

scientific article published on November 2008

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.181.9.5885
P932PMC publication ID2597624
P698PubMed publication ID18941177
P5875ResearchGate publication ID23403177

P2093author name stringQi Yang
Irwin D Bernstein
Lela Kardava
Christine Milcarek
Lisa Borghesi
Barbara Varnum-Finney
Anthony St Leger
Kathleen Martincic
P2860cites workPromotion of cell cycle progression by basic helix-loop-helix E2AQ24291573
Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interactionQ24302447
Gradient of E2A activity in B-cell developmentQ28215170
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangementsQ28243194
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALLQ28254962
p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.Q28360415
Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCLQ28508494
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemiaQ29614324
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cellsQ29615006
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stressQ29615562
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cellsQ29616552
Hematopoiesis: an evolving paradigm for stem cell biologyQ29619676
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitorsQ33328820
NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewalQ33920140
The role of E2A-PBX1 in leukemogenesisQ34405471
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in miceQ73086909
Hematopoietic stem cell quiescence maintained by p21cip1/waf1Q73532192
Expression of CD27 on murine hematopoietic stem and progenitor cellsQ73542908
Functional assessment of precursors from murine bone marrow suggests a sequence of early B lineage differentiation eventsQ73649057
Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged miceQ78762514
Accelerated Notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activationQ79880417
Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47Q80233317
Regulation of E2A gene expression in B-lymphocyte developmentQ34547316
Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage developmentQ34773120
Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cellsQ35611589
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenanceQ36007697
Helix-loop-helix proteins and lymphocyte developmentQ36292892
Positive and negative regulation of V(D)J recombination by the E2A proteinsQ36367956
Defects in hemopoietic stem cell activity in Ikaros mutant miceQ36375493
Developmental separation of V(D)J recombinase expression and initiation of IgH recombination in B lineage progenitors in vivoQ36399225
B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitorsQ36399230
Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2AQ36399448
E47 is required for V(D)J recombinase activity in common lymphoid progenitorsQ36403067
E2A promotes the survival of precursor and mature B lymphocytesQ36432006
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.Q36560174
High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout miceQ36574096
Early hematopoietic lineage restrictions directed by Ikaros.Q37413012
Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivoQ38524360
E2A proteins enforce a proliferation checkpoint in developing thymocytesQ39315636
Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell developmentQ39974270
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomasQ40023076
Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteinsQ40023533
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphomaQ40337542
The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cellsQ40609821
Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells.Q40781039
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signalingQ40844523
Pre-B cell leukemia associated with chromosome translocation 1;19.Q42252773
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrowQ44114694
Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminaseQ44756999
Both E12 and E47 allow commitment to the B cell lineageQ45129651
Identification of a lineage of multipotent hematopoietic progenitors.Q45969717
Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-betaQ46116890
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.Q46455047
Kit regulates maintenance of quiescent hematopoietic stem cells.Q46771607
Regulation of p21(WAF1) expression during normal myeloid differentiation.Q48004798
Heterogeneity of Flt3-expressing multipotent progenitors in mouse bone marrow.Q52037447
Ikaros is critical for B cell differentiation and function.Q52123185
The Biology of Hematopoietic Stem CellsQ58043095
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia preventionQ59067116
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacityQ64008447
5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulationQ68707978
New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemiaQ71000476
Functional isolation and characterization of human hematopoietic stem cellsQ71666169
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)5885-5894
P577publication date2008-11-01
P1433published inJournal of ImmunologyQ3521441
P1476titleE47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors
P478volume181