| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Bonnie B Blomberg | |
| Daniela Frasca | |||
| Richard L Riley | |||
| P2860 | cites work | Regulation of BOB.1/OBF.1 stability by SIAH | Q24291513 |
| The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1 | Q24550350 | ||
| Phosphorylation of E47 as a potential determinant of B-cell-specific activity | Q24647666 | ||
| E protein function in lymphocyte development | Q28203458 | ||
| Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice | Q28204342 | ||
| CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes | Q28216904 | ||
| The role of E-proteins in B- and T-lymphocyte development | Q28273104 | ||
| The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain | Q28594115 | ||
| Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells | Q28616666 | ||
| AU-rich elements: characterization and importance in mRNA degradation | Q29547896 | ||
| Changes in the B-cell repertoire with age. | Q33846340 | ||
| Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development | Q34197865 | ||
| Proteolysis, caloric restriction and aging. | Q34232168 | ||
| Age-related changes in lymphocyte development and function | Q34293466 | ||
| Age-related changes in protein oxidation and proteolysis in mammalian cells. | Q34420880 | ||
| Molecular mechanism of class switch recombination: linkage with somatic hypermutation | Q34542246 | ||
| Regulation of E2A gene expression in B-lymphocyte development | Q34547316 | ||
| Hyper-IgM syndromes: a model for studying the regulation of class switch recombination and somatic hypermutation generation | Q34797812 | ||
| Regulation of early lymphocyte development by E2A family proteins | Q35012075 | ||
| Notch signalling in B cells | Q35090096 | ||
| Post-transcriptional regulation of gene expression by degradation of messenger RNAs | Q35110948 | ||
| Positive selection focuses the VH12 B-cell repertoire towards a single B1 specificity with survival function | Q35666663 | ||
| Mechanisms of selection mediated by interleukin-7, the preBCR, and hemokinin-1 during B-cell development | Q35666672 | ||
| Ubiquitin ligases and the immune response | Q35698411 | ||
| AID: how does it aid antibody diversity? | Q35800376 | ||
| Many levels of control of V gene rearrangement frequency | Q35830398 | ||
| Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments | Q35963602 | ||
| Effect of age on the immunoglobulin class switch | Q36016727 | ||
| Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow | Q36230070 | ||
| Immunological studies of aging. IV. The contribution of thymic involution to the immune deficiencies of aging mice and reversal with thymopoietin32-36 | Q36341969 | ||
| Antigen responsiveness of the mature and generative B cell populations of aged mice | Q36347680 | ||
| Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice | Q36359879 | ||
| Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice | Q36365981 | ||
| H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation | Q36370913 | ||
| Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A | Q36399448 | ||
| Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice | Q36399584 | ||
| Ku70 is required for late B cell development and immunoglobulin heavy chain class switching | Q36401127 | ||
| Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A | Q36402675 | ||
| B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. | Q36560174 | ||
| Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities | Q37368153 | ||
| Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination | Q37527405 | ||
| Identification of cyclin D3 as a direct target of E2A using DamID. | Q39998534 | ||
| Immune function in aged mice. I. T-cell responsiveness using phytohaemagglutinin as a functional probe | Q40649273 | ||
| Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. | Q40937465 | ||
| CD79 alpha/CD79 beta heterodimers are expressed on pro-B cell surfaces without associated mu heavy chain | Q41073512 | ||
| EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes | Q41101434 | ||
| E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination | Q41702555 | ||
| Ku80 is required for immunoglobulin isotype switching | Q41821763 | ||
| Aging and developmental transitions in the B cell lineage | Q44198590 | ||
| Levels of E2A protein expression in B cell precursors are stage-dependent and inhibited by stem cell factor (c-kit ligand). | Q44249431 | ||
| E-proteins directly regulate expression of activation-induced deaminase in mature B cells | Q44419402 | ||
| Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis | Q44633425 | ||
| Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase | Q44756999 | ||
| Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover | Q44968876 | ||
| Antibody class switching: uncoupling S region accessibility from transcription | Q44985373 | ||
| Both E12 and E47 allow commitment to the B cell lineage | Q45129651 | ||
| Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta | Q46116890 | ||
| The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors | Q47677663 | ||
| Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice | Q47846154 | ||
| Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells | Q47862867 | ||
| Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire. | Q52012960 | ||
| The response in old mice: positive and negative immune memory after priming in early age. | Q52017064 | ||
| Lifetime of plasma cells in the bone marrow. | Q52042101 | ||
| Contribution of Receptor Editing to the Antibody Repertoire | Q57198265 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 30-47 | |
| P577 | publication date | 2005-06-01 | |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | B cells, E2A, and aging | |
| P478 | volume | 205 |
| Q38128010 | A comparative review of aging and B cell function in mice and humans |
| Q37236031 | Aging and the immune system |
| Q37398750 | B cells and aging: molecules and mechanisms |
| Q50079317 | CD43-independent augmentation of mouse T-cell function by glycoprotein cleaving enzymes |
| Q34411132 | Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis. |
| Q37359108 | Deviation of the B cell pathway in senescent mice is associated with reduced surrogate light chain expression and altered immature B cell generation, phenotype, and light chain expression |
| Q91330081 | Do haematopoietic stem cells age? |
| Q83146478 | E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia |
| Q39888535 | E2A participates in a fine control of pre-mature B-cell apoptosis mediated by B-cell receptor signaling via transcriptional regulation of survivin, IAP2 and caspase-8 genes |
| Q37228632 | Effects of fenbendazole on the murine humoral immune system. |
| Q92775918 | Elevated Neutrophil to Lymphocyte Ratio in Older Adults with Cocaine Use Disorder as a Marker of Chronic Inflammation |
| Q30238724 | From Immunologically Archaic to Neoteric Glycovaccines |
| Q64075206 | Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age |
| Q34492738 | Immunization of aged mice with a pneumococcal conjugate vaccine combined with an unmethylated CpG-containing oligodeoxynucleotide restores defective immunoglobulin G antipolysaccharide responses and specific CD4+-T-cell priming to young adult levels |
| Q26861735 | Immunosenescence and organ transplantation |
| Q38063349 | Impact of immunosenescence on transplant outcome |
| Q37026934 | In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors |
| Q36929586 | Innate immunity and aging |
| Q64122246 | Lymphoid-Biased Hematopoietic Stem Cells Are Maintained with Age and Efficiently Generate Lymphoid Progeny |
| Q37181211 | MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis |
| Q28585695 | Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis |
| Q64072872 | Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis |
| Q90594776 | Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A |
| Q35193959 | Vaccinomics and a new paradigm for the development of preventive vaccines against viral infections |
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