Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination

scientific article published on 24 October 2013

Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2013.09.031
P932PMC publication ID3951903
P698PubMed publication ID24209747
P5875ResearchGate publication ID258426513

P2093author name stringHong Zan
Zhenming Xu
Paolo Casali
Guideng Li
Egest J Pone
Clayton A White
Ken L Hayama
Tonika Lam
Daniel C Tran
P2860cites workA role for the RNA pol II-associated PAF complex in AID-induced immune diversificationQ36340835
Immunoglobulin class-switch DNA recombination: induction, targeting and beyondQ36534234
Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locusQ36949047
Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regionsQ36954874
Epigenetics of the antibody responseQ37097751
H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombinationQ37124102
S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombinationQ37292763
Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.Q37323207
Signals and combinatorial functions of histone modificationsQ37870190
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencersQ38348243
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.Q39664674
HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomainQ39777525
AID-dependent histone acetylation is detected in immunoglobulin S regionsQ40328411
The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacementQ40626080
14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation.Q41887944
Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombinationQ41999588
E-proteins directly regulate expression of activation-induced deaminase in mature B cellsQ44419402
A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazoneQ46188677
Phosphorylation of histone H3 is required for proper chromosome condensation and segregationQ77310947
Translating the Histone CodeQ22065840
The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1Q24294979
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readersQ24300155
Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patternsQ24322623
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substratesQ24337929
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathwayQ24632504
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationQ24645030
Combinatorial patterns of histone acetylations and methylations in the human genomeQ24647290
Regulation of Aicda expression and AID activityQ26853622
Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivationQ28299905
Recombination centres and the orchestration of V(D)J recombinationQ28307066
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNAQ28512692
PTIP promotes chromatin changes critical for immunoglobulin class switch recombinationQ28585503
RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complexQ28910442
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickersQ29547350
Regulation and function of NF-kappaB transcription factors in the immune systemQ29616427
Multivalent engagement of chromatin modifications by linked binding modulesQ29617236
Histones: annotating chromatinQ29619913
Histone acetyltransferase complexes: one size doesn't fit allQ29620006
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytesQ33757410
B cell TLRs and induction of immunoglobulin class-switch DNA recombinationQ33893517
Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutationQ34333819
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5Q34357060
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombinationQ34438355
Complex regulation and function of activation-induced cytidine deaminaseQ34958445
Balancing AID and DNA repair during somatic hypermutationQ34966633
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombinationQ35055116
Readers of histone modificationsQ35092783
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.Q35144590
Helix-loop-helix proteins and lymphocyte developmentQ36292892
P433issue3
P921main subjectantibodyQ79460
P304page(s)702-714
P577publication date2013-10-24
P1433published inCell ReportsQ5058165
P1476titleCombinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination
P478volume5

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cites work (P2860)
Q42029829A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression(1,2,3).
Q28265992AID targeting: old mysteries and new challenges
Q37683558AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination.
Q43177792B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses
Q43196711B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses
Q64078028Distinct Requirements of CHD4 during B Cell Development and Antibody Response
Q42080563Editorial: Epigenetics of B Cells and Antibody Responses
Q26781345Epigenetic Codes Programing Class Switch Recombination
Q49634141Epigenetic regulation in B-cell maturation and its dysregulation in autoimmunity
Q26772330Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response
Q55011560Epigenomic Modifications Mediating Antibody Maturation.
Q33673290Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells
Q55092495Generating and repairing genetically programmed DNA breaks during immunoglobulin class switch recombination.
Q34647217Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses
Q49589250Identification of multiple roles for histone acetyltransferase 1 in replication-coupled chromatin assembly
Q37323207Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.
Q52597611KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.
Q41788723Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching
Q34549827MicroRNAs in lupus
Q38993930Nascent Connections: R-Loops and Chromatin Patterning
Q28087424RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome
Q37642661Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.
Q26853622Regulation of Aicda expression and AID activity
Q35055116Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination
Q37835582Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus

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