Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination

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Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...880414L
P356DOI10.1371/JOURNAL.PONE.0080414
P932PMC publication ID3840166
P698PubMed publication ID24282540
P5875ResearchGate publication ID258956266

P2093author name stringZhenming Xu
Paolo Casali
Guideng Li
Egest J Pone
Clayton A White
Lisa M Thomas
Tonika Lam
P2860cites workPost-replicative base excision repair in replication fociQ24534209
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responsesQ24624348
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathwayQ24632504
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationQ24645030
Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrestQ24673660
NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol. Comparison with the Vpr N-terminal (1-51) and C-terminal (52-96) domainsQ27639447
Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitorQ27673714
AID targeting is dependent on RNA polymerase II pausingQ27692655
The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombinationQ28271930
HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptorsQ28302759
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutationQ28586304
14-3-3 proteins: structure, function, and regulationQ29619100
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.Q30374809
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in miceQ30857687
Replication protein A interacts with AID to promote deamination of somatic hypermutation targetsQ31099047
Regulation of replication protein A functions in DNA mismatch repair by phosphorylationQ33244982
Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cellsQ33280958
Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.Q33479706
A coming-of-age story: activation-induced cytidine deaminase turns 10.Q33605445
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytesQ33757410
Interactions between natural killer cells and antibody Fc result in enhanced antibody neutralization of human immunodeficiency virus type 1.Q33781055
The role of activation-induced deaminase in lupus nephritisQ38065211
Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cellsQ39027259
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.Q39664674
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.Q40627624
HIV-1 Vpr displays natural protein-transducing properties: implications for viral pathogenesis.Q40690555
AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].Q41870415
Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombinationQ41999588
Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cellsQ42630118
HIV-1 accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of forkhead transcription factors by interfering with their binding to 14-3-3 proteins: potential clinical implications regarding the insulin resistance of HIV-1-infectQ45199116
Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.Q45420564
Fc receptor but not complement binding is important in antibody protection against HIV.Q46545827
Two levels of protection for the B cell genome during somatic hypermutation.Q46755254
Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rateQ46775963
Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.Q53589401
Insights into DNA deaminasesQ79487889
Vpr protein of human immunodeficiency virus type 1 binds to 14-3-3 proteins and facilitates complex formation with Cdc25C: implications for cell cycle arrestQ33834244
14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forksQ33886547
A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAsQ33947941
Protein kinase A phosphorylation activates Vpr-induced cell cycle arrest during human immunodeficiency virus type 1 infectionQ33990739
Cytidine deaminases: AIDing DNA demethylation?Q34164873
Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombinationQ34217718
PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cellsQ34249818
Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutationQ34333819
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5Q34357060
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycleQ34537165
Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysisQ34648424
Mechanism and regulation of class switch recombinationQ34764888
Complex regulation and function of activation-induced cytidine deaminaseQ34958445
Role of HIV-1 Vpr in AIDS pathogenesis: relevance and implications of intravirion, intracellular and free Vpr.Q35087037
Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombinationQ35105143
Role of complement in the control of HIV dynamics and pathogenesisQ35134722
14-3-3 proteins as potential therapeutic targetsQ35510924
X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joiningQ35849574
Genome-wide phosphoacetylation of histone H3 at Drosophila enhancers and promotersQ36021740
14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motifQ36100873
DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutationQ36193082
B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cellsQ36368837
DNA repair in antibody somatic hypermutationQ36493831
AID and Igh switch region-Myc chromosomal translocationsQ36511486
Immunoglobulin class-switch DNA recombination: induction, targeting and beyondQ36534234
14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 VprQ36665575
Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombinationQ36759880
Epigenetics of the antibody responseQ37097751
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombinationQ37115233
The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequenceQ37167699
HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduitsQ37444317
Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombinationQ37634047
AID and partners: for better and (not) for worseQ37858052
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminaseQ38043045
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)e80414
P577publication date2013-11-25
P1433published inPLOS OneQ564954
P1476titleScaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination
P478volume8

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cites work (P2860)
Q3885214814-3-3γ affects mTOR pathway and regulates lactogenesis in dairy cow mammary epithelial cells
Q37683558AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination.
Q43177792B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses
Q43196711B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses
Q27973894Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum
Q37634047Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination
Q42316216Correction: Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination
Q36748153Dysregulated 14-3-3 Family in Peripheral Blood Leukocytes of Patients with Schizophrenia
Q26781345Epigenetic Codes Programing Class Switch Recombination
Q36367583Genome-Wide Analysis Reveals Selective Modulation of microRNAs and mRNAs by Histone Deacetylase Inhibitor in B Cells Induced to Undergo Class-Switch DNA Recombination and Plasma Cell Differentiation

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