scholarly article | Q13442814 |
P819 | ADS bibcode | 2009PNAS..106.6736G |
P356 | DOI | 10.1073/PNAS.0810808106 |
P932 | PMC publication ID | 2672500 |
P698 | PubMed publication ID | 19351893 |
P5875 | ResearchGate publication ID | 24262835 |
P2093 | author name string | Michael S Neuberger | |
Cristina Rada | |||
Roland Geisberger | |||
P2860 | cites work | Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains | Q24292247 |
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1 | Q24307678 | ||
Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1 | Q24336265 | ||
AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization | Q24531345 | ||
MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation | Q24646923 | ||
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase | Q24653222 | ||
Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate | Q24802780 | ||
miR-181b negatively regulates activation-induced cytidine deaminase in B cells | Q28508305 | ||
Identification of a signal for rapid export of proteins from the nucleus | Q29547742 | ||
Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358. | Q33206242 | ||
Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics | Q35571380 | ||
Importin beta: conducting a much larger cellular symphony | Q35938681 | ||
Dependence of antibody gene diversification on uracil excision. | Q36294382 | ||
Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase | Q36399510 | ||
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase | Q36456463 | ||
Proteasomal degradation restricts the nuclear lifespan of AID | Q36699771 | ||
Molecular mechanisms of antibody somatic hypermutation. | Q36747477 | ||
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development | Q36853393 | ||
Evidence for specific nucleocytoplasmic transport pathways used by leucine-rich nuclear export signals | Q37202345 | ||
Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks | Q40566152 | ||
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. | Q40627624 | ||
Qualitative highly divergent nuclear export signals can regulate export by the competition for transport cofactors in vivo | Q40788028 | ||
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice | Q42286497 | ||
AID mutant analyses indicate requirement for class-switch-specific cofactors | Q42798287 | ||
Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis | Q46485635 | ||
Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2. | Q46490209 | ||
Importin-mediated nuclear translocation of galectin-3. | Q50710813 | ||
A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals | Q73598439 | ||
P433 | issue | 16 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 6736-6741 | |
P577 | publication date | 2009-04-07 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence | |
P478 | volume | 106 |
Q39664674 | 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. |
Q33605445 | A coming-of-age story: activation-induced cytidine deaminase turns 10. |
Q41870415 | AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected]. |
Q43112724 | AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model. |
Q28085553 | AID/APOBEC deaminases and cancer |
Q37683558 | AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination. |
Q36592764 | Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers. |
Q34427913 | Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins |
Q37994933 | Activation-induced cytidine deaminase in antibody diversification and chromosome translocation |
Q64097227 | Activation-induced deaminase (AID) localizes to the nucleus in brief pulses |
Q39756116 | Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID. |
Q41777384 | Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia |
Q26799165 | Antibody Affinity Maturation in Fishes-Our Current Understanding |
Q35930290 | Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells. |
Q37587676 | C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion |
Q24295504 | CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31 |
Q35768862 | Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID. |
Q34152519 | Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis |
Q36316915 | Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications |
Q34958445 | Complex regulation and function of activation-induced cytidine deaminase |
Q46566272 | Conflict of interests: multiple signal peptides with diverging goals |
Q35289306 | Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm. |
Q90057553 | Current insights into the mechanism of mammalian immunoglobulin class switch recombination |
Q35546818 | Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A). |
Q37304668 | Dealing with dangerous accidents: DNA double-strand breaks take centre stage. Symposium on Genome Instability and DNA Repair |
Q52716066 | Diversity of Immunoglobulin (Ig) Isotypes and the Role of Activation-Induced Cytidine Deaminase (AID) in Fish. |
Q35144590 | Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination. |
Q27300740 | Etoposide induces nuclear re-localisation of AID |
Q37776353 | Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis |
Q36534234 | Immunoglobulin class-switch DNA recombination: induction, targeting and beyond |
Q36633302 | Immunoglobulin class-switch recombination deficiencies |
Q34438294 | Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair |
Q35744148 | Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination |
Q37323207 | Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A. |
Q34170147 | Lysine residue at position 22 of the AID protein regulates its class switch activity. |
Q42837072 | Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching |
Q33829729 | Potential roles of activation-induced cytidine deaminase in promotion or prevention of autoimmunity in humans |
Q28540726 | Processive DNA demethylation via DNA deaminase-induced lesion resolution |
Q35669089 | REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase |
Q35055116 | Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination |
Q41771273 | The dependence of Ig class-switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin |
Q28750273 | The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination |
Q41981500 | The mechanisms regulating the subcellular localization of AID. |
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