Antibody Affinity Maturation in Fishes-Our Current Understanding

scientific article

Antibody Affinity Maturation in Fishes-Our Current Understanding is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/BIOLOGY4030512
P932PMC publication ID4588147
P698PubMed publication ID26264036
P5875ResearchGate publication ID281058457

P50authorBrad G MagorQ42623397
P2860cites workPhagocytosis in the spleen of the sunfish Lepomis spp.Q50923943
Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: the translesion synthesis model of somatic hypermutationQ56902254
Activation-induced cytidine deaminase (AID) is strongly expressed in the fetal bovine ileal Peyer's patch and spleen and is associated with expansion of the primary antibody repertoire in the absence of exogenous antigensQ57112529
Localization of immune complexes and heat-aggregated immunoglobulin in the carp Cyprinus carpio LQ72676090
Immunocytochemical detection of Ig-positive cells in blood, lymphoid organs and the gut associated lymphoid tissue of the turbot (Scophthalmus maximus)Q74155520
Evolution of autoantibody responses via somatic hypermutation outside of germinal centersQ74813307
The nucleotide targets of somatic mutation and the role of selection in immunoglobulin heavy chains of a teleost fishQ82310892
Somatic hypermutation of TCR γ V genes in the sandbar sharkQ84957344
Antigen localization in the lymphoid organs of carp (Cyprinus carpio)Q93658226
A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharksQ28235720
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cellsQ28509339
Characterization of arrangement and expression of the T cell receptor gamma locus in the sandbar sharkQ28752670
Fate mapping reveals origin and dynamics of lymph node follicular dendritic cellsQ30579711
Somatic hypermutation and junctional diversification at Ig heavy chain loci in the nurse sharkQ33229014
Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminaseQ33379345
The cellular context of AID expressing cells in fish lymphoid tissuesQ33526902
Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritisQ33611035
Generation and repair of AID-initiated DNA lesions in B lymphocytesQ33690522
Targets of somatic hypermutation within immunoglobulin light chain genes in zebrafishQ33744266
Error-Prone DNA Repair Activity during Somatic Hypermutation in Shark B LymphocytesQ34222332
Affinity maturation in trout: clonal dominance of high affinity antibodies late in the immune responseQ34429757
First molecular and biochemical analysis of in vivo affinity maturation in an ectothermic vertebrate.Q34478580
Determinism and stochasticity during maturation of the zebrafish antibody repertoireQ34750049
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.Q35289306
Origin of immunoglobulin isotype switchingQ35989631
Dependence of antibody gene diversification on uracil excision.Q36294382
AID from bony fish catalyzes class switch recombinationQ36403021
Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+ IgD+ CD27+ B cell repertoire in infantsQ36699760
Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: possible role in antigen-driven reactions in the absence of germinal centersQ36734151
Molecular mechanisms of antibody somatic hypermutation.Q36747477
The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequenceQ37167699
Shark IgW C region diversification through RNA processing and isotype switchingQ37339890
Production of 19S IgM antibodies with restricted heterogeneity from sharksQ37547947
Activation-induced cytidine deaminase structure and functions: a species comparative viewQ37846899
Transcriptional regulation of teleost Aicda genes. Part 1 - suppressors of promiscuous promotersQ39070275
Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sectionsQ40874465
What limits affinity maturation of antibodies in Xenopus--the rate of somatic mutation or the ability to select mutants?Q41544908
Somatic mutation in ectothermic vertebrates: musings on selection and origins.Q41711161
Structural characterization of the melano-macrophage centres (MMC) of goldfish Carassius auratusQ42020989
Lack of heterogeneity in anti-hapten antibodies of a phylogenetically primitive sharkQ42242821
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- miceQ42286497
Cloning and expression of the AID gene in the channel catfishQ42623288
Hypermutation in shark immunoglobulin light chain genes results in contiguous substitutionsQ42674915
Antibody-antigen kinetics following immunization of rainbow trout (Oncorhynchus mykiss) with a T-cell dependent antigenQ43790603
Antibody structural variation in rainbow trout fluidsQ44915434
The strength of B cell interaction with antigen determines the degree of IgM polymerizationQ44952815
Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early developmentQ44974088
Identification of the activation-induced cytidine deaminase gene from zebrafish: an evolutionary analysisQ45027465
Differences in the enzymatic efficiency of human and bony fish AID are mediated by a single residue in the C terminus modulating single-stranded DNA bindingQ45167924
B cell clonal expansion and somatic hypermutation of Ig variable heavy chain genes in the synovial membrane of patients with osteoarthritisQ46256317
Isolation and cytochemical characterization of melanomacrophages and melanomacrophage clusters from goldfish (Carassius auratus, L.).Q46663444
Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID.Q46807599
Analysis of mutational lineage trees from sites of primary and secondary Ig gene diversification in rabbits and chickensQ47810397
A new model of sheep Ig diversification: shifting the emphasis toward combinatorial mechanisms and away from hypermutationQ48024863
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)512-24
P577publication date2015-01-01
P1433published inBiologyQ17509951
P1476titleAntibody Affinity Maturation in Fishes-Our Current Understanding
P478volume4

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cites work (P2860)
Q46334657Biochemical Regulatory Features of Activation-Induced Cytidine Deaminase Remain Conserved from Lampreys to Humans
Q55208667Diversity in the Cow Ultralong CDR H3 Antibody Repertoire.
Q52716066Diversity of Immunoglobulin (Ig) Isotypes and the Role of Activation-Induced Cytidine Deaminase (AID) in Fish.
Q55021404T Cell Receptor Alpha Chain Genes in the Teleost Ballan Wrasse (Labrus bergylta) Are Subjected to Somatic Hypermutation.

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