Identification of a signal for rapid export of proteins from the nucleus

scientific article (publication date: 11 August 1995)

Identification of a signal for rapid export of proteins from the nucleus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/0092-8674(95)90435-2
P953full work available at URLhttps://doi.org/10.1016/0092-8674(95)90435-2
https://api.elsevier.com/content/article/PII:0092867495904352?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:0092867495904352?httpAccept=text/plain
P3181OpenCitations bibliographic resource ID723916
P698PubMed publication ID7634336
P5875ResearchGate publication ID15565484

P2093author name stringJ. L. Meinkoth
W. Wen
R. Y. Tsien
S. S. Taylor
P2860cites workMolecular cloning of a rat testis form of the inhibitor protein of cAMP-dependent protein kinaseQ24564820
Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motifQ27934225
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferaseQ28131695
The expression and intracellular distribution of the heat-stable protein kinase inhibitor is cell cycle regulatedQ28512174
The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasmQ28646841
Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNAQ28646843
Nuclear protein localizationQ29397060
A short amino acid sequence able to specify nuclear locationQ29547781
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequenceQ29547917
The biogenesis of lysosomesQ29617860
Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activityQ29618284
Shuttling of pre-mRNA binding proteins between nucleus and cytoplasmQ29618907
Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear importQ29620195
Major nucleolar proteins shuttle between nucleus and cytoplasmQ29620425
The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigenQ33334884
Mutational definition of the human immunodeficiency virus type 1 Rev activation domain.Q34132236
Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signalQ34162300
Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocationQ34175285
Structure and function of the nuclear pore complexQ35161320
The nuclear membraneQ35532347
Nuclear localization signals also mediate the outward movement of proteins from the nucleusQ35620460
Translocation of RNA-coated gold particles through the nuclear pores of oocytesQ36218652
A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivoQ36219388
Cytoplasmic transport of ribosomal subunits microinjected into the Xenopus laevis oocyte nucleus: a generalized, facilitated processQ36223645
Export of mRNA from microinjected nuclei of Xenopus laevis oocytesQ36531559
Nuclear import-export: in search of signals and mechanisms.Q36663596
Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusionQ37376044
tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation processQ37512771
How proteins enter the nucleusQ37632736
Protein transport into and within chloroplastsQ37921963
Scanning mutagenesis of the arginine-rich region of the human immunodeficiency virus type 1 Rev trans activatorQ40042468
RNA exportQ40400161
Mechanisms of nuclear protein import.Q40475438
Signal sequence recognition and protein targeting to the endoplasmic reticulum membraneQ40611469
Cytosolic factors in nuclear transport: what's importin?Q40655599
mRNA nuclear exportQ40672468
Mitochondrial protein import: mechanisms, components and energeticsQ40696648
Nuclear shuttling: the default pathway for nuclear proteins?Q40839193
Fluorescence ratio imaging of cyclic AMP in single cellsQ41695021
Expression in Escherichia coli and characterization of the heat-stable inhibitor of the cAMP-dependent protein kinaseQ42019486
Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits importQ45854241
Crosstalk between domains in the regulatory subunit of cAMP-dependent protein kinase: influence of amino terminus on cAMP binding and holoenzyme formationQ46159553
Shuttling proteins go both waysQ47981722
Nuclear export of proteins: the role of nuclear retention.Q49136533
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factorsQ49486533
Monomethylated cap structures facilitate RNA export from the nucleus.Q50804073
Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev functionQ58611466
Synthetic peptides as nuclear localization signalsQ59060621
Protein-mediated nuclear export of RNA: 5S rRNA containing small RNPs in xenopus oocytesQ68410009
Mutants in a conserved region near the carboxy-terminus of HIV-1 Rev identify functionally important residues and exhibit a dominant negative phenotypeQ68535819
Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear poresQ70378768
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)463-73
P577publication date1995-08-11
P1433published inCellQ655814
P1476titleIdentification of a signal for rapid export of proteins from the nucleus
P478volume82

Reverse relations

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Q28580800Endogenous protein kinase inhibitor gamma terminates immediate-early gene expression induced by cAMP-dependent protein kinase (PKA) signaling: termination depends on PKA inactivation rather than PKA export from the nucleus
Q48955413Energy- and temperature-dependent in vitro export of RNA from synthetic nuclei
Q55240469Enhancement of nucleocytoplasmic export of HTLV-1 Rex mRNA through cis and trans interactions of the mRNA with the complex of Rex protein and Rex-responsive element.
Q33806883Epstein-Barr virus EB2 protein exports unspliced RNA via a Crm-1-independent pathway
Q39673832Epstein–Barr virus latent membrane protein 1 increases chemo-resistance of cancer cells via cytoplasmic sequestration of Pim-1
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Q37202345Evidence for specific nucleocytoplasmic transport pathways used by leucine-rich nuclear export signals
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Q41150735Exogenously injected nuclear import factor p10/NTF2 inhibits signal-mediated nuclear import and export of proteins in living cells
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Q35899426Export of hepatitis B virus RNA on a Rev-like pathway: inhibition by the regenerating liver inhibitory factor IkappaB alpha.
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Q34173576Fructose-1,6-bisphosphatase opposes renal carcinoma progression
Q35181303Function and interaction of the coupled genes responsible for Pik-h encoded rice blast resistance.
Q50444700Functional analysis of amino-terminal domains of the photoreceptor phytochrome B.
Q39579073Functional analysis of the human immunodeficiency virus type 1 Rev protein oligomerization interface.
Q43898008Functional identification of multiple nucleocytoplasmic trafficking signals in the broad-spectrum resistance protein RPW8.2.
Q39550602Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2.
Q28504583G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214
Q27933501GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function
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Q34716828Genotoxic stress and cellular stress alter the subcellular distribution of human T-cell leukemia virus type 1 tax through a CRM1-dependent mechanism
Q35813119Globin gene transfer as a potential treatment for the beta-thalassaemias and sickle cell disease
Q39242535HAX-1 is a nucleocytoplasmic shuttling protein with a possible role in mRNA processing.
Q39829692HDAC1 in axonal degeneration: A matter of subcellular localization
Q28569045HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage
Q28289718HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAs
Q24671943HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing
Q37152235HTLV-1 Yin and Yang: Rex and p30 master regulators of viral mRNA trafficking.
Q24563424Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1
Q34083087Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway.
Q33800212Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathways
Q36944428Heterodimerization with small Maf proteins enhances nuclear retention of Nrf2 via masking the NESzip motif
Q40131964High-content classification of nucleocytoplasmic import or export inhibitors
Q40057597Hijacking of the nucleolar protein fibrillarin by TGB1 is required for cell-to-cell movement of Barley stripe mosaic virus
Q40090638Homodimerization antagonizes nuclear export of survivin
Q34694952How to monitor nuclear shuttling
Q38761454Human cytomegalovirus UL84 protein contains two nuclear export signals and shuttles between the nucleus and the cytoplasm
Q24623475Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis
Q33898275Human ribosomal protein L5 contains defined nuclear localization and export signals
Q48373564Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
Q35194372ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif
Q34340089Identification and characterization of the nuclear import and export signals of the mammalian Ste20-like protein kinase 3.
Q35943693Identification and characterization of three novel nuclear export signals in the influenza A virus nucleoprotein
Q36666347Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry
Q24629579Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity
Q33889493Identification of a copper-induced intramolecular interaction in the transcription factor Mac1 from Saccharomyces cerevisiae.
Q40854794Identification of a functional nuclear export sequence in BRCA1.
Q24801461Identification of a novel Rev-interacting cellular protein
Q30883874Identification of a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases
Q33809951Identification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1
Q24291357Identification of functional domains involved in BTG1 cell localization
Q44487694Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta
Q33966215Identification of novel Saccharomyces cerevisiae proteins with nuclear export activity: cell cycle-regulated transcription factor ace2p shows cell cycle-independent nucleocytoplasmic shuttling
Q44699027Identification of novel nuclear export and nuclear localization-related signals in human heat shock cognate protein 70.
Q42797767Identification of nuclear export signals in antizyme-1.
Q28580253Identification of nuclear import and export signals within the structure of the zinc finger protein TIS11
Q64074864Identification of nuclear localization signal and nuclear export signal of VP1 from the chicken anemia virus and effects on VP2 shuttling in cells
Q46068635Identification, analysis, and use of nuclear export signals in Saccharomyces cerevisiae
Q50438183Immune activation mediated by the late blight resistance protein R1 requires nuclear localization of R1 and the effector AVR1.
Q60908486Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy
Q40225593Impaired nuclear import of mammalian Dlx4 proteins as a consequence of rapid sequence divergence
Q35823256Import and export of nuclear proteins: focus on the nucleocytoplasmic movements of two different species of mammalian estrogen receptor
Q40646969Importance of nuclear localization of apoptin for tumor-specific induction of apoptosis
Q33868789Importin beta can mediate the nuclear import of an arginine-rich nuclear localization signal in the absence of importin alpha
Q48059143Importin provides a link between nuclear protein import and U snRNA export
Q48014918Importins and exportins: how to get in and out of the nucleus
Q40968433Importins/karyopherins meet nucleoporins
Q33597374In or out? Regulating nuclear transport
Q28278287In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32
Q40243200In vitro reconstitution of a heterotrimeric nucleoporin complex consisting of recombinant Nsp1p, Nup49p, and Nup57p
Q35006325Induction of protein-protein interactions in live cells using light
Q34685189Influenza A virus NS2 protein mediates vRNP nuclear export through NES-independent interaction with hCRM1
Q38323233Inhibition of CRM1-mediated nucleocytoplasmic transport: triggering human melanoma cell apoptosis by perturbing multiple cellular pathways
Q24523655Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus Rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1
Q36816824Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates
Q22003948Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm
Q27863701Inhibition of nuclear export of ribonucleoprotein complexes of influenza virus by leptomycin B.
Q27667119Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain
Q28202182Interaction of HCF-1 with a cellular nuclear export factor
Q30442529Interaction of HTLV-1 Tax protein with calreticulin: implications for Tax nuclear export and secretion
Q41115678Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase
Q24310012Interaction of the HIV-1 rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5
Q24314389Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta
Q33573230Interplay of PKA and Rac: fine-tuning of Rac localization and signaling
Q40776139Intracellular localization of the Ret finger protein depends on a functional nuclear export signal and protein kinase C activation.
Q40143081Intracellular localization of the SARS coronavirus protein 9b: evidence of active export from the nucleus
Q24685623Involvement of 14-3-3 proteins in nuclear localization of telomerase
Q28369696Involvement of CRM1, a nuclear export receptor, in mRNA export in mammalian cells and fission yeast
Q42796003Involvement of protein phosphatase 2A nuclear accumulation and subsequent inactivation of activator protein-1 in leptomycin B-inhibited cyclin D1 expression
Q28204072Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes
Q27932702Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins
Q33511005Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr
Q38610444Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae
Q33695055Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo
Q34462563Kinetics of protein import into isolated Xenopus oocyte nuclei
Q24548041LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity
Q29620175Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA
Q24533258Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation
Q42123194Light-regulated nuclear import and degradation of Arabidopsis phytochrome-A N-terminal fragments
Q39427537Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus.
Q45303152Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells
Q43583330Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.
Q33778864Loss of IkappaB alpha-mediated control over nuclear import and DNA binding enables oncogenic activation of c-Rel
Q27935098Ltv1 is required for efficient nuclear export of the ribosomal small subunit in Saccharomyces cerevisiae
Q24317750MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10
Q30887023MBDin, a novel MBD2-interacting protein, relieves MBD2 repression potential and reactivates transcription from methylated promoters.
Q42649263MPF localization is controlled by nuclear export
Q45756471Mapping of multiple RNA binding sites of human T-cell lymphotropic virus type I rex protein within 5'- and 3'-Rex response elements
Q53190949Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export.
Q27939754Mechanism and a peptide motif for targeting peripheral proteins to the yeast inner nuclear membrane
Q35799545Mechanism and regulation of nucleocytoplasmic trafficking of smad
Q42414560Mechanism underlying the iron-dependent nuclear export of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae
Q22065647Mechanisms of Receptor-Mediated Nuclear Import and Nuclear Export
Q28587170Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
Q44434225Methionine-101 from one strain of H5N1 NS1 protein determines its IFN-antagonizing ability and subcellular distribution pattern
Q45133860Methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineurin/Crz1-mediated pathway in Saccharomyces cerevisiae
Q30370684Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.
Q30303652Mitogen-activated protein kinases: specific messages from ubiquitous messengers
Q61800190Modulating CRISPR gene drive activity through nucleocytoplasmic localization of Cas9 in
Q73949946Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B
Q37073173Molecular mechanisms of Nrf2-mediated antioxidant response
Q83824189Morbillivirus nucleoprotein possesses a novel nuclear localization signal and a CRM1-independent nuclear export signal
Q28270274Mouse Disabled1 (DAB1) is a nucleocytoplasmic shuttling protein
Q24538823Mouse mammary tumor virus encodes a self-regulatory RNA export protein and is a complex retrovirus
Q30453521Mta has properties of an RNA export protein and increases cytoplasmic accumulation of Epstein-Barr virus replication gene mRNA.
Q93253670Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A
Q39581878Multimer formation is not essential for nuclear export of human T-cell leukemia virus type 1 Rex trans-activator protein
Q35130465Multiple pathways regulate intracellular shuttling of MoKA, a co-activator of transcription factor KLF7
Q28566914Multiple protein domains determine the cell type-specific nuclear distribution of the catalytic subunit required for apolipoprotein B mRNA editing
Q44819117Multiplicity of the beta form of the cAMP-dependent protein kinase inhibitor protein generated by post-translational modification and alternate translational initiation
Q24305971Mutation of SOD1 in ALS: a gain of a loss of function
Q33292384Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K.
Q28235567Mutations in the nuclear export signal of human ran-binding protein RanBP1 block the Rev-mediated posttranscriptional regulation of human immunodeficiency virus type 1
Q41899994N-terminal domain of the androgen receptor contains a region that can promote cytoplasmic localization
Q40889482N-terminal region, C-terminal region, nuclear export signal, and deacetylation activity of histone deacetylase-3 are essential for the viability of the DT40 chicken B cell line
Q27665346NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1
Q50638648NES-REBS: A novel nuclear export signal prediction method using regular expressions and biochemical properties.
Q34169526NESbase version 1.0: a database of nuclear export signals
Q36234505NESdb: a database of NES-containing CRM1 cargoes
Q35261339NESmapper: accurate prediction of leucine-rich nuclear export signals using activity-based profiles
Q50495025NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins.
Q59060751NF-AT activation requires suppression of Crm1-dependent export by calcineurin
Q34033135NF-kappa B and HIV: linking viral and immune activation
Q24682180NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum
Q47109750NLSdb-major update for database of nuclear localization signals and nuclear export signals
Q24674855NXT1 is necessary for the terminal step of Crm1-mediated nuclear export
Q39453336Neoplastic transformation by Notch requires nuclear localization
Q35173879Nerve growth factor-dependent regulation of NADE-induced apoptosis.
Q38222192Nervous translation, do you get the message? A review of mRNPs, mRNA-protein interactions and translational control within cells of the nervous system
Q36313072New insights into biliverdin reductase functions: linking heme metabolism to cell signaling
Q27712238Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies
Q27939125Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunit
Q50317533NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals.
Q24644057Npp106p, a Schizosaccharomyces pombe nucleoporin similar to Saccharomyces cerevisiae Nic96p, functionally interacts with Rae1p in mRNA export
Q40417213Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif.
Q55040338Nuclear Export Inhibition for Pancreatic Cancer Therapy.
Q38730799Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export
Q36131085Nuclear Localised MORE SULPHUR ACCUMULATION1 Epigenetically Regulates Sulphur Homeostasis in Arabidopsis thaliana.
Q33926317Nuclear RNA export pathways.
Q24801020Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II.
Q34021302Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein.
Q28475960Nuclear export and import of human hepatitis B virus capsid protein and particles
Q43428742Nuclear export in plants. Use of geminivirus movement proteins for a cell-based export assay
Q34302112Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals
Q42158928Nuclear export of LIM-kinase 1, mediated by two leucine-rich nuclear-export signals within the PDZ domain
Q34460235Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein
Q41828411Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint
Q24568233Nuclear export of late HIV-1 mRNAs occurs via a cellular protein export pathway
Q41477073Nuclear export of proteins and RNAs
Q47889024Nuclear export of proteins in plants: AtXPO1 is the export receptor for leucine-rich nuclear export signals in Arabidopsis thaliana
Q34989400Nuclear export of ribosomal subunits
Q33887076Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence
Q37712229Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Q27939703Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast
Q34679479Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor
Q36559957Nuclear export signal-interacting protein forms complexes with lamin A/C-Nups to mediate the CRM1-independent nuclear export of large hepatitis delta antigen
Q24657473Nuclear export-independent inhibition of Foxa2 by insulin
Q27867703Nuclear import and export of influenza virus nucleoprotein.
Q37761199Nuclear import and export of plant virus proteins and genomes
Q77903798Nuclear import and export of proteins: the molecular basis for intracellular signaling
Q39217465Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress.
Q31685709Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda
Q34024485Nuclear import by karyopherin-βs: Recognition and inhibition
Q39451343Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway
Q28580866Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase
Q24291211Nuclear import/export of hRPF1/Nedd4 regulates the ubiquitin-dependent degradation of its nuclear substrates
Q28260234Nuclear localization and export signals of the human aryl hydrocarbon receptor
Q40851268Nuclear localization and intramolecular cleavage of N-terminally deleted NS5A protein of hepatitis C virus
Q33786457Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences
Q28270343Nuclear localization of Tob is important for regulation of its antiproliferative activity
Q28585964Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence
Q42819066Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK.
Q24644611Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression
Q47070229Nuclear mislocalization of enzymatically active RanGAP causes segregation distortion in Drosophila
Q40884705Nuclear mitogen-activated protein kinase activation by protein kinase czeta during reoxygenation after ischemic hypoxia
Q27939266Nuclear pore proteins are involved in the biogenesis of functional tRNA
Q78244462Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade
Q33936678Nuclear targeting signal recognition: a key control point in nuclear transport?
Q36105057Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation
Q33665634Nuclear transport and transcriptional regulation
Q34381398Nuclear transport of human immunodeficiency virus type 1, visna virus, and equine infectious anemia virus Rev proteins: identification of a family of transferable nuclear export signals.
Q28245436Nuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteins
Q36263598Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleus
Q40756043Nuclear-localization-signal-dependent and nuclear-export-signal-dependent mechanisms determine the localization of 5-lipoxygenase
Q47225550Nuclear-localized and deregulated calcium- and calmodulin-dependent protein kinase activates rhizobial and mycorrhizal responses in Lotus japonicus
Q36286196Nuclear-to-cytoplasmic relocalization of the proliferating cell nuclear antigen (PCNA) during differentiation involves a chromosome region maintenance 1 (CRM1)-dependent export and is a prerequisite for PCNA antiapoptotic activity in mature neutroph
Q34115273Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function
Q33888123Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
Q28212923Nucleo-cytoplasmic trafficking of metal-regulatory transcription factor 1 is regulated by diverse stress signals
Q52606191Nucleocytoplasmic distribution is required for activation of resistance by the potato NB-LRR receptor Rx1 and is balanced by its functional domains.
Q50941903Nucleocytoplasmic partitioning of tobacco N receptor is modulated by SGT1.
Q36273838Nucleocytoplasmic recycling of the nuclear localization signal receptor alpha subunit in vivo is dependent on a nuclear export signal, energy, and RCC1
Q44245356Nucleocytoplasmic shuttling and CRM1-dependent MHC class I peptide presentation of human cytomegalovirus pp65.
Q41961089Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro
Q40101680Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance
Q35920894Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination
Q35678324Nucleocytoplasmic shuttling of signal transducers.
Q30503332Nucleocytoplasmic shuttling of the HSV-2 serine/threonine kinase Us3
Q34625857Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region
Q30453773Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides.
Q44272650Nucleocytoplasmic transport and cell proliferation
Q36574246Nucleocytoplasmic transport of macromolecules
Q24294319Nucleocytoplasmic transport of proteins and poly(A)+ RNA in reconstituted Tpr-less nuclei in living mammalian cells
Q73168294Nucleocytoplasmic transport: Inside out regulation
Q43098275Nucleocytoplasmic transport: a thermodynamic mechanism
Q29547904Nucleocytoplasmic transport: signals, mechanisms and regulation
Q36601697Nucleus-localized 21.5-kDa myelin basic protein promotes oligodendrocyte proliferation and enhances neurite outgrowth in coculture, unlike the plasma membrane-associated 18.5-kDa isoform
Q28238313Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export
Q24552769Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
Q35715592Optical recording of signal-mediated protein transport through single nuclear pore complexes
Q39790257Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA.
Q33901796Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element
Q37459134P68 RNA helicase is a nucleocytoplasmic shuttling protein
Q39874406PEST-dependent cytoplasmic retention of v-Rel by I(kappa)B-alpha: evidence that I(kappa)B-alpha regulates cellular localization of c-Rel and v-Rel by distinct mechanisms.
Q28511197PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation
Q83230317PHLPP1 counter-regulates STAT1-mediated inflammatory signaling
Q41326275Pararetro- and retrovirus RNA: splicing and the control of nuclear export
Q42233071PepSite: prediction of peptide-binding sites from protein surfaces
Q24537305Permeability of single nuclear pores
Q38725956Phenethyl isothiocyanate suppresses the metastasis of ovarian cancer associated with the inhibition of CRM1-mediated nuclear export and mTOR-STAT3 pathway
Q40927204Phospholipase C-delta1 contains a functional nuclear export signal sequence
Q46289164Phosphorylation at the nuclear localization signal of Ca2+/calmodulin-dependent protein kinase II blocks its nuclear targeting
Q34076444Phosphorylation of nucleoporin Tpr governs its differential localization and is required for its mitotic function
Q28609161Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
Q28140841Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro
Q35208788Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121.
Q33648134Polyvalent Rev decoys act as artificial Rev-responsive elements
Q40860006Potato NPH3/RPT2-Like Protein StNRL1, Targeted by a Phytophthora infestans RXLR Effector, Is a Susceptibility Factor
Q22008785PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I
Q35198286Prediction of leucine-rich nuclear export signal containing proteins with NESsential
Q33718450Probing plant cell structure and function with viral movement proteins
Q34384095Protein export from the nucleus
Q41505004Protein kinase A anchoring
Q37111119Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions.
Q36561338Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay
Q41010427Protein translocation: nuclear export--out of the dark
Q50717787Protein-protein interactions and nuclear trafficking of coat protein and betaC1 protein associated with Bhendi yellow vein mosaic disease.
Q34510072Protein-responsive ribozyme switches in eukaryotic cells
Q36120273Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase
Q33824767Proteomics and functional analyses of pepper abscisic acid-responsive 1 (ABR1), which is involved in cell death and defense signaling
Q47736041Purification and structural study of the beta form of human cAMP-dependent protein kinase inhibitor
Q49485954Putative reaction intermediates in Crm1-mediated nuclear protein export
Q40788028Qualitative highly divergent nuclear export signals can regulate export by the competition for transport cofactors in vivo
Q35853452RNA binding is more critical to the suppression of silencing function of Cucumber mosaic virus 2b protein than nuclear localization
Q39967264RNA length defines RNA export pathway
Q73258077RNA movement between the nucleus and the cytoplasm
Q24685628Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export
Q26822052Ran-dependent nuclear export mediators: a structural perspective
Q73561184Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2
Q24522587RanBP3 influences interactions between CRM1 and its nuclear protein export substrates
Q33959492RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase
Q46400037Rapid targeting of nuclear proteins to the cytoplasm
Q42028214Rate and extent of protein localization is controlled by peptide-binding domain association kinetics and morphology
Q28653243Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange
Q30717105Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization
Q57378150Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis
Q34367559Recognition of nuclear targeting signals by Karyopherin-β proteins
Q37477637Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export
Q28646696Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs
Q42467275Redistribution of the kinesin-II subunit KAP from cilia to nuclei during the mitotic and ciliogenic cycles in sea urchin embryos
Q38753107Region of Nipah virus C protein responsible for shuttling between the cytoplasm and nucleus
Q38302656Regulated nuclear-cytoplasmic localization of CCAAT/enhancer-binding protein delta in osteoblasts
Q24554197Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1
Q42824508Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation
Q29619289Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle
Q63681677Regulation of CDC25B phosphatases subcellular localization
Q24679707Regulation of PRAK subcellular location by p38 MAP kinases
Q39448268Regulation of RelA subcellular localization by a putative nuclear export signal and p50.
Q28646231Regulation of STAT1 nuclear export by Jak1
Q34400900Regulation of Syk by phosphorylation on serine in the linker insert
Q36058189Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein
Q34284337Regulation of estrogen receptor nuclear export by ligand-induced and p38-mediated receptor phosphorylation
Q36571657Regulation of gene expression by cyclic GMP-dependent protein kinase requires nuclear translocation of the kinase: identification of a nuclear localization signal
Q30309361Regulation of nuclear import and export by the GTPase Ran.
Q33937097Regulation of nuclear import and export.
Q40141471Regulation of nucleo-cytoplasmic shuttling of human annexin A2: a proposed mechanism
Q28281545Regulation of serum amyloid A protein expression during the acute-phase response
Q40929312Regulation of the nucleocytoplasmic distribution of Snf1-Gal83 protein kinase
Q33968448Reproductive function in protein kinase inhibitor-deficient mice
Q34755286Restriction of human immunodeficiency virus type 1 Rev function in murine A9 cells involves the Rev C-terminal domain
Q37598771Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting
Q34033155Rev protein and its cellular partners
Q38025392Role of Nucleocytoplasmic RNA Transport during the Life Cycle of Retroviruses
Q40970933Role of regulatory subunits and protein kinase inhibitor (PKI) in determining nuclear localization and activity of the catalytic subunit of protein kinase A.
Q33797502Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins
Q42500320SHH ventralizes the otocyst by maintaining basal PKA activity and regulating GLI3 signaling
Q44575326SR proteins preferentially associate with mRNAs in the nucleus and facilitate their export to the cytoplasm
Q28592913STRA8 shuttles between nucleus and cytoplasm and displays transcriptional activity
Q24678180SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex
Q27930639Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations.
Q27932322Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization
Q30304057Selection and characterization of human immunodeficiency virus type 1 mutants that are resistant to inhibition by the transdominant negative RevM10 protein
Q34050698Selection of HIV replication inhibitors: chemistry and biology
Q22008541Selection system for genes encoding nuclear-targeted proteins
Q44792760Separate nuclear import pathways converge on the nucleoporin Nup153 and can be dissected with dominant-negative inhibitors
Q36234511Sequence and structural analyses of nuclear export signals in the NESdb database
Q42129111Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.
Q40015345Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.
Q38984568Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity
Q34344979Signals that dictate nuclear, nucleolar, and cytoplasmic shuttling of the gamma(1)34.5 protein of herpes simplex virus type 1
Q90316911Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Q24537637Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation
Q48292866Spatial regulation of the KH domain RNA-binding protein Rnc1 mediated by a Crm1-independent nuclear export system in Schizosaccharomyces pombe
Q24648900Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them
Q26781513Structural Basis of Targeting the Exportin CRM1 in Cancer
Q27619633Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding
Q24604395Structural basis for leucine-rich nuclear export signal recognition by CRM1
Q24319780Structural basis for the antiproliferative activity of the Tob-hCaf1 complex
Q64082973Structural prerequisites for CRM1-dependent nuclear export signaling peptides: accessibility, adapting conformation, and the stability at the binding site
Q42834827Structural requirements for nuclear localization of GCMa/Gcm-1.
Q42069888Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.
Q27919622Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis
Q28565236Subcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscle
Q27931033Subcellular localization of Aft1 transcription factor responds to iron status in Saccharomyces cerevisiae
Q42157217Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.
Q33604949Subcellular localization of V2 protein of Tomato leaf curl Java virus by using green fluorescent protein and yeast hybrid system.
Q36274092Subnuclear trafficking of glucocorticoid receptors in vitro: chromatin recycling and nuclear export
Q27939559Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance
Q33206242Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358.
Q40323899Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals
Q38296460Synthesis of Fluorescent Potassium Ion-Sensing Probes Based on a Thrombin-Binding DNA Aptamer-Peptide Conjugate
Q24534064TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus
Q28276214TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus
Q47709624TORC1 signaling exerts spatial control over microtubule dynamics by promoting nuclear export of Stu2.
Q35971615TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways
Q30498709Targeted in vivo O-GlcNAc sensors reveal discrete compartment-specific dynamics during signal transduction
Q104795052Targeting XPO1 enhances innate immune response and inhibits KSHV lytic replication during primary infection by nuclear stabilization of the p62 autophagy adaptor protein
Q33549679Temperature modulates plant defense responses through NB-LRR proteins
Q27938506The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals
Q33647481The C-terminal region but not the Arg-X-Pro repeat of Epstein-Barr virus protein EB2 is required for its effect on RNA splicing and transport
Q41860863The CRM1 nuclear export protein in normal development and disease.
Q22010221The DHHC domain: a new highly conserved cysteine-rich motif
Q42917946The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export
Q39684683The Epstein-Barr virus SM protein is functionally similar to ICP27 from herpes simplex virus in viral infections
Q36224577The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression
Q33886877The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein
Q42583695The Levinthal paradox of the interactome
Q28076985The Life-Cycle of the HIV-1 Gag-RNA Complex
Q58746531The Molecular Basis for Specificity at the Level of the Protein Kinase a Catalytic Subunit
Q24538664The NS2 proteins of parvovirus minute virus of mice are required for efficient nuclear egress of progeny virions in mouse cells.
Q92238936The Nuclear-Localized RxLR Effector PvAvh74 From Plasmopara viticola Induces Cell Death and Immunity Responses in Nicotiana benthamiana
Q41665276The ORF012 gene of Marek's disease virus type 1 produces a spliced transcript and encodes a novel nuclear phosphoprotein essential for virus growth.
Q24812592The POU protein Oct-6 is a nucleocytoplasmic shuttling protein.
Q41690723The Q-rich/PST domain of the AHR regulates both ligand-induced nuclear transport and nucleocytoplasmic shuttling
Q54987435The Rules and Functions of Nucleocytoplasmic Shuttling Proteins.
Q42057495The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export
Q29616325The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus
Q35943783The bovine immunodeficiency virus Rev protein: identification of a novel nuclear import pathway and nuclear export signal among retroviral Rev/Rev-like proteins
Q39753171The carboxy-terminal region of the human immunodeficiency virus type 1 protein Rev has multiple roles in mediating CRM1-related Rev functions
Q24554506The carboxyl terminus of RNA helicase A contains a bidirectional nuclear transport domain
Q37669242The checkpoint-dependent nuclear accumulation of Rho1p exchange factor Rgf1p is important for tolerance to chronic replication stress
Q30448360The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway
Q41349765The cyst nematode effector protein 10A07 targets and recruits host posttranslational machinery to mediate its nuclear trafficking and to promote parasitism in Arabidopsis
Q45768146The expression of hepatitis B virus polymerase in hepatocytes during chronic HBV infection
Q90101958The force-sensitive protein Ajuba regulates cell adhesion during epithelial morphogenesis
Q38356070The hepatitis B virus posttranscriptional regulatory element is composed of two subelements
Q35969160The human T-cell leukemia virus Rex protein
Q35868902The human T-cell leukemia virus type 1 posttranscriptional trans-activator Rex contains a nuclear export signal
Q28646657The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences
Q33796895The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expression
Q24323008The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA export
Q28254641The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export
Q33888022The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins
Q33781297The maximal size of protein to diffuse through the nuclear pore is larger than 60kDa
Q30441924The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion.
Q33327050The neogenin intracellular domain regulates gene transcription via nuclear translocation
Q24554414The net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock
Q37356339The neural F-box protein NFB42 mediates the nuclear export of the herpes simplex virus type 1 replication initiator protein (UL9 protein) after viral infection
Q27932021The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast
Q34986205The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p).
Q73168297The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae
Q24641817The nucleoporin nup153 plays a critical role in multiple types of nuclear export
Q45053935The pepper cysteine/histidine-rich DC1 domain protein CaDC1 binds both RNA and DNA and is required for plant cell death and defense response
Q33967931The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver
Q24548981The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function
Q74589678The role of Ca2+/calmodulin-dependent protein kinases within the nucleus
Q44103395The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export
Q37167699The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence
Q42798672The transformation suppressor protein Pdcd4 shuttles between nucleus and cytoplasm and binds RNA.
Q34003929The ubiquitin-conjugating enzyme UbcM2 can regulate the stability and activity of the antioxidant transcription factor Nrf2.
Q41159170The v-Ki-Ras oncogene alters cAMP nuclear signaling by regulating the location and the expression of cAMP-dependent protein kinase IIbeta
Q27937376The yeast nucleoporin Nup53p specifically interacts with Nic96p and is directly involved in nuclear protein import
Q27934181The yeast nucleoporin rip1p contributes to multiple export pathways with no essential role for its FG-repeat region.
Q27938846The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing
Q28140575The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1
Q41137776Three cardiovirus Leader proteins equivalently inhibit four different nucleocytoplasmic trafficking pathways
Q73514223Tissue-specific expression and regulation by 1,25(OH)2D3 of chick protein kinase inhibitor (PKI) mRNA
Q41066972Toward the molecular dissection of protein import into nuclei
Q36547212Tracking STAT nuclear traffic
Q24530637Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein
Q44519371Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90.
Q29615611Transport into and out of the nucleus
Q42805175Transport of galectin-3 between the nucleus and cytoplasm. II. Identification of the signal for nuclear export
Q34066757Transport of macromolecules between the nucleus and the cytoplasm
Q40558822Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation.
Q48022498Tuning CRISPR-Cas9 Gene Drives in Saccharomyces cerevisiae
Q37492673Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities.
Q34171484Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicing
Q41616095Two well-defined motifs in the cAMP-dependent protein kinase inhibitor (PKIalpha) correlate with inhibitory and nuclear export function
Q50668347UV-B promotes rapid nuclear translocation of the Arabidopsis UV-B specific signaling component UVR8 and activates its function in the nucleus.
Q24291831UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation
Q34123401Ubc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication.
Q28138877Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization
Q35202823Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export
Q34300344Unique motif for nucleolar retention and nuclear export regulated by phosphorylation
Q36891198Upregulation of a novel gene by freezing exposure in the freeze-tolerant wood frog (Rana sylvatica).
Q36491242ValidNESs: a database of validated leucine-rich nuclear export signals
Q28210950Vascular endothelial cells express isoforms of protein kinase A inhibitor
Q39741142Venezuelan equine Encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin alpha/beta that obstructs nuclear pore complex function
Q28276399Vigilin contains a functional nuclear localisation sequence and is present in both the cytoplasm and the nucleus
Q34429972Viral RNA export
Q33859528Viral movement proteins as probes for intracellular and intercellular trafficking in plants
Q38148317Viruses challenge selectivity barrier of nuclear pores
Q36726881Visual and both non-visual arrestins in their "inactive" conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasm
Q47261311Visualizing nuclear-localized RNA using transient expression system in plants
Q46217445Wheat cryptochromes: subcellular localization and involvement in photomorphogenesis and osmotic stress responses.
Q39135290XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy.
Q55517575Xpo7 is a broad-spectrum exportin and a nuclear import receptor.
Q27934431Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export
Q28822154cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry
Q28564835cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells
Q24651660eEF1A is a novel component of the mammalian nuclear protein export machinery
Q46178328mDia2 shuttles between the nucleus and the cytoplasm through the importin-{alpha}/{beta}- and CRM1-mediated nuclear transport mechanism
Q42652785mRNA sequence of the Xenopus laevis paxillin gene and its expression
Q33716182p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials
Q39902123p53 Oligomerization is essential for its C-terminal lysine acetylation
Q37131508p53 SUMOylation promotes its nuclear export by facilitating its release from the nuclear export receptor CRM1
Q64230440tRNA Processing and Subcellular Trafficking Proteins Multitask in Pathways for Other RNAs
Q52725550α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis.

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