scholarly article | Q13442814 |
P2093 | author name string | Joachim J Li | |
Van Q Nguyen | |||
Kaoru Irie | |||
Muluye E Liku | |||
Audrey W Rosales | |||
P2860 | cites work | Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase | Q24310880 |
Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding | Q24313280 | ||
Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis | Q24515107 | ||
Disruption of mechanisms that prevent rereplication triggers a DNA damage response | Q24529993 | ||
The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast | Q24532802 | ||
Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization | Q24533531 | ||
Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures | Q24545600 | ||
Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage | Q24558657 | ||
Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint | Q24563819 | ||
Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization | Q24617490 | ||
Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6 | Q24656841 | ||
Loss of Geminin induces rereplication in the presence of functional p53 | Q24676493 | ||
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region | Q24685870 | ||
CRM1 is an export receptor for leucine-rich nuclear export signals | Q27860453 | ||
Uninterrupted MCM2-7 function required for DNA replication fork progression | Q27929772 | ||
The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5. | Q27932153 | ||
A group of interacting yeast DNA replication genes | Q27932669 | ||
Characterization of karyopherin cargoes reveals unique mechanisms of Kap121p-mediated nuclear import | Q27934921 | ||
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus | Q27937350 | ||
A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae | Q27938381 | ||
Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. | Q27938391 | ||
The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions | Q27939320 | ||
Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7. | Q27939332 | ||
Exportin 1 (Crm1p) is an essential nuclear export factor | Q27939696 | ||
The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication | Q27939757 | ||
Clb6/Cdc28 and Cdc14 regulate phosphorylation status and cellular localization of Swi6 | Q27939995 | ||
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs | Q28131708 | ||
DNA replication in eukaryotic cells | Q28131747 | ||
Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms | Q28204020 | ||
Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation | Q28248715 | ||
Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression | Q28250231 | ||
Mutations in SID2, a novel gene in Saccharomyces cerevisiae, cause synthetic lethality with sic1 deletion and may cause a defect during S phase | Q28354208 | ||
Identification of a signal for rapid export of proteins from the nucleus | Q29547742 | ||
CRM1 is responsible for intracellular transport mediated by the nuclear export signal | Q29547861 | ||
Targets of the cyclin-dependent kinase Cdk1 | Q29616479 | ||
Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle | Q29619289 | ||
Evidence for a role of CRM1 in signal-mediated nuclear protein export | Q29620231 | ||
Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A. | Q30312052 | ||
Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. | Q33775448 | ||
Regulation of nuclear localization: a key to a door | Q33804320 | ||
Nuclear targeting signal recognition: a key control point in nuclear transport? | Q33936678 | ||
Multiple mechanisms regulate subcellular localization of human CDC6. | Q33946248 | ||
Control of DNA replication and chromosome ploidy by geminin and cyclin A | Q34323837 | ||
Regulation of early events in chromosome replication | Q34349937 | ||
Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle | Q35204963 | ||
Ectopic induction of Clb2 in early G1 phase is sufficient to block prereplicative complex formation in Saccharomyces cerevisiae | Q35917356 | ||
The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication | Q36731987 | ||
Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly | Q36951274 | ||
Spc98p directs the yeast gamma-tubulin complex into the nucleus and is subject to cell cycle-dependent phosphorylation on the nuclear side of the spindle pole body | Q38611058 | ||
MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint | Q39231854 | ||
The IFNAR1 subunit of the type I IFN receptor complex contains a functional nuclear localization sequence. | Q40482485 | ||
Cyclin/CDK regulates the nucleocytoplasmic localization of the human papillomavirus E1 DNA helicase. | Q40487864 | ||
Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae. | Q40789015 | ||
The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae | Q42676980 | ||
Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. | Q46384443 | ||
Regulation of nuclear import by phosphorylation adjacent to nuclear localization signals | Q48004807 | ||
Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. | Q48098747 | ||
Drosophila double-parked is sufficient to induce re-replication during development and is regulated by cyclin E/CDK2. | Q52087804 | ||
Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases | Q57985194 | ||
Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control | Q59098617 | ||
Nuclear accumulation of Saccharomyces cerevisiae Mcm3 is dependent on its nuclear localization sequence | Q62950086 | ||
Biochemical function of mouse minichromosome maintenance 2 protein | Q74392968 | ||
P433 | issue | 10 | |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 5026-5039 | |
P577 | publication date | 2005-08-10 | |
P1433 | published in | Molecular Biology of the Cell | Q2338259 |
P1476 | title | CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication | |
P478 | volume | 16 |
Q30524859 | A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations. |
Q99557396 | Age-dependent decline in stress response capacity revealed by proteins dynamics analysis |
Q21203553 | An overview of Cdk1-controlled targets and processes |
Q24337293 | Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expression |
Q97676617 | Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53 |
Q42618089 | CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6 |
Q39830232 | Cdk1-mediated phosphorylation of Cdc7 suppresses DNA re-replication |
Q35936445 | Cell cycle synchronization by nutrient modulation |
Q42852173 | Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase |
Q34611390 | Cotransport of the heterodimeric small subunit of the Saccharomyces cerevisiae ribonucleotide reductase between the nucleus and the cytoplasm |
Q35729891 | Cyclin and cyclin-dependent kinase substrate requirements for preventing rereplication reveal the need for concomitant activation and inhibition |
Q92123028 | Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle |
Q36846089 | Cyclin-specific control of ribosomal DNA segregation |
Q37825828 | DNA replication licensing control and rereplication prevention |
Q41017840 | Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits |
Q28534302 | Design principles of the yeast G1/S switch |
Q60045737 | Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks |
Q27304870 | Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1 |
Q44793417 | Dynamic localization of the DNA replication proteins MCM5 and MCM7 in plants |
Q21145819 | Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species |
Q36189305 | Evolutionary diversification of MCM3 genes in Xenopus laevis and Danio rerio |
Q45952950 | Extracellular signal-regulated kinase 2 (ERK-2) mediated phosphorylation regulates nucleo-cytoplasmic shuttling and cell growth control of Ras-associated tumor suppressor protein, RASSF2. |
Q24544016 | Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant |
Q33691497 | Incremental Genetic Perturbations to MCM2-7 Expression and Subcellular Distribution Reveal Exquisite Sensitivity of Mice to DNA Replication Stress |
Q36631219 | Interplay between S-cyclin-dependent kinase and Dbf4-dependent kinase in controlling DNA replication through phosphorylation of yeast Mcm4 N-terminal domain |
Q57753359 | Keap1-MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa |
Q46207142 | Linkage between phosphorylation of the origin recognition complex and its ATP binding activity in Saccharomyces cerevisiae |
Q35541125 | LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins |
Q42571971 | Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7 |
Q38546818 | Mechanisms Regulating Protein Localization. |
Q39017132 | Mechanisms and regulation of DNA replication initiation in eukaryotes |
Q26827264 | Mechanisms for initiating cellular DNA replication |
Q34104063 | MicroRNA-31 suppresses medulloblastoma cell growth by inhibiting DNA replication through minichromosome maintenance 2 |
Q34328693 | Minichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis |
Q27936752 | Nascent transcription of MCM2-7 is important for nuclear localization of the minichromosome maintenance complex in G1 |
Q43444340 | Norcantharidin inhibits pre-replicative complexes assembly of HepG2 cells |
Q40078388 | Nuclear DNA Replication in Trypanosomatids: There Are No Easy Methods for Solving Difficult Problems |
Q27933989 | Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein |
Q27687877 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights |
Q33906513 | Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage |
Q36008189 | Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells |
Q39532495 | ProteoConnections: a bioinformatics platform to facilitate proteome and phosphoproteome analyses |
Q38381047 | Proteomic Screen for Cellular Targets of the Vaccinia Virus F10 Protein Kinase Reveals that Phosphorylation of mDia Regulates Stress Fiber Formation |
Q47172564 | Pump-free multi-well-based microfluidic system for high-throughput analysis of size-control relative genes in budding yeast |
Q37956282 | Quality control in the initiation of eukaryotic DNA replication |
Q36798615 | RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. |
Q38120365 | Regulating DNA replication in eukarya |
Q36464843 | Regulating the licensing of DNA replication origins in metazoa |
Q92106577 | Regulation of Cell Cycle Entry and Exit: A Single Cell Perspective |
Q37777965 | Regulation of the initiation step of DNA replication by cyclin-dependent kinases. |
Q36140799 | Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites |
Q35230092 | Reliable cell cycle commitment in budding yeast is ensured by signal integration |
Q50336589 | Sequence elements in both subunits of the DNA fragmentation factor are essential for its nuclear transport. |
Q37351846 | Specific genetic interactions between spindle assembly checkpoint proteins and B-Type cyclins in Saccharomyces cerevisiae |
Q52837802 | Studying the Role of the Mitotic Exit Network in Cytokinesis. |
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Q27934845 | Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs |
Q35213348 | The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex. |
Q37451513 | The Mcm complex: unwinding the mechanism of a replicative helicase. |
Q42253458 | The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth |
Q37294890 | The interplay between chromosome stability and cell cycle control explored through gene-gene interaction and computational simulation |
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