scholarly article | Q13442814 |
P50 | author | Marilia Cascalho | Q56858816 |
Jeffrey L Platt | Q87911589 | ||
P2093 | author name string | Xiaosheng Wu | |
P2860 | cites work | Cancer Research | Q326097 |
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage | Q22010200 | ||
HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes | Q24291378 | ||
Nuclear and nucleolar targeting of human ribosomal protein S6 | Q24321240 | ||
CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity | Q24554535 | ||
A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation | Q40800224 | ||
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint | Q41303489 | ||
Mismatch repair co-opted by hypermutation. | Q43917262 | ||
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors | Q49486533 | ||
Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer | Q61946741 | ||
Mutations and loss of expression of a mismatch repair gene, hMLH1, in leukemia and lymphoma cell lines | Q73126110 | ||
Signaling mismatch repair in cancer | Q73143600 | ||
Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells | Q73626700 | ||
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters | Q24564850 | ||
The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2 | Q24596494 | ||
Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function | Q24632994 | ||
Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis | Q27766073 | ||
Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha. | Q27929951 | ||
Eukaryotic DNA mismatch repair | Q27939116 | ||
Mutation of a mutL homolog in hereditary colon cancer | Q28114939 | ||
Nucleocytoplasmic transport: the soluble phase | Q28131723 | ||
The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer | Q28137782 | ||
hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA | Q28138775 | ||
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting | Q28506440 | ||
Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process | Q28507129 | ||
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern | Q28510640 | ||
Meiotic pachytene arrest in MLH1-deficient mice | Q28510650 | ||
Severe attenuation of the B cell immune response in Msh2-deficient mice | Q28585021 | ||
Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications | Q28586687 | ||
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2 | Q28910215 | ||
Identification of a signal for rapid export of proteins from the nucleus | Q29547742 | ||
Mismatch repair in replication fidelity, genetic recombination, and cancer biology | Q29616483 | ||
Steady-state regulation of the human DNA mismatch repair system. | Q33896699 | ||
Nuclear targeting signal recognition: a key control point in nuclear transport? | Q33936678 | ||
Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha | Q34123282 | ||
DNA mismatch repair and cancer | Q34164892 | ||
Regulation of p53 localization | Q34254613 | ||
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins | Q34425450 | ||
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs | Q34554581 | ||
The contribution of nuclear compartmentalization to gene regulation | Q34574321 | ||
The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA. | Q34657088 | ||
The role of DNA repair in somatic hypermutation of immunoglobulin genes | Q36400909 | ||
Expression of the DNA mismatch repair proteins hMLH1 and hPMS2 in normal human tissues | Q36431145 | ||
Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations | Q36570003 | ||
Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export | Q37477637 | ||
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct | Q37522716 | ||
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis | Q38293261 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 3320-3328 | |
P577 | publication date | 2003-05-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha | |
Dimerization of MLH1 and PMS2 Limits Nuclear Localization of MutLα | |||
P478 | volume | 23 |
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Q36614680 | An intact Pms2 ATPase domain is not essential for male fertility |
Q48233207 | Analysis of clinically relevant somatic mutations in high-risk head and neck cutaneous squamous cell carcinoma. |
Q34820495 | Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q |
Q34163755 | C-terminal fluorescent labeling impairs functionality of DNA mismatch repair proteins |
Q55423138 | CRABS CLAW Acts as a Bifunctional Transcription Factor in Flower Development. |
Q53292592 | Cancer risk assessment using genetic panel testing: considerations for clinical application. |
Q33208352 | Challenges and pitfalls in HNPCC screening by microsatellite analysis and immunohistochemistry |
Q28277364 | Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 |
Q35036377 | Complex relationship between mismatch repair proteins and MBD4 during immunoglobulin class switch recombination |
Q83227500 | Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome |
Q24647002 | DNA mismatch repair: molecular mechanism, cancer, and ageing |
Q62817582 | DNA repair processes are critical mediators of p53-dependent tumor suppression |
Q36946520 | Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination |
Q39695410 | Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair |
Q40084513 | MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine |
Q54419889 | MLPA mutation detection in Argentine HNPCC and FAP families. |
Q36009224 | Modulation of microRNA processing by mismatch repair protein MutLα. |
Q35829272 | Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1) |
Q38029584 | Pathological assessment of mismatch repair gene variants in Lynch syndrome: past, present, and future |
Q28256131 | Prokaryotic DNA mismatch repair |
Q37308166 | Reciprocal regulation of nuclear import of the yeast MutSalpha DNA mismatch repair proteins Msh2 and Msh6. |
Q33778759 | Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells |
Q34236531 | Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells |
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Q47317424 | Sub-cellular localization analysis of MSH6 missense mutations does not reveal an overt MSH6 nuclear transport impairment |
Q48332104 | The Changing Landscape of Lynch Syndrome due to PMS2 Mutations. |
Q40222264 | The E705K mutation in hPMS2 exerts recessive, not dominant, effects on mismatch repair |
Q24298905 | Thymosin beta 4 expression and nuclear transport are regulated by hMLH1 |
Q37694831 | Two co-existing germline mutations P53 V157D and PMS2 R20Q promote tumorigenesis in a familial cancer syndrome |
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