| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M410601200 |
| P698 | PubMed publication ID | 15917227 |
| P50 | author | Chi Chen | Q56203812 |
| P2093 | author name string | Xin Yue | |
| Renping Zhou | |||
| Wenge Li | |||
| Mohit R Jain | |||
| A-N Tony Kong | |||
| Vidya Hebbar | |||
| P2860 | cites work | Transport between the cell nucleus and the cytoplasm | Q22065411 |
| THE HIV-1 REV PROTEIN | Q22241975 | ||
| Cadmium Induces Nuclear Export of Bach1, a Transcriptional Repressor of Heme Oxygenase-1 Gene | Q24294975 | ||
| Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells | Q24338209 | ||
| Classification of human B-ZIP proteins based on dimerization properties | Q24540084 | ||
| Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1 | Q24563424 | ||
| Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region | Q24563505 | ||
| Protein kinase cascades activated by stress and inflammatory cytokines | Q41075765 | ||
| The heme-responsive element of the mouse heme oxygenase-1 gene is an extended AP-1 binding site that resembles the recognition sequences for MAF and NF-E2 transcription factors | Q41204736 | ||
| An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site | Q42456162 | ||
| Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene | Q43955949 | ||
| Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium | Q44222495 | ||
| Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles | Q44373729 | ||
| Mutual exclusivity of DNA binding and nuclear localization signal recognition by the yeast transcription factor GAL4: implications for nonviral DNA delivery | Q45855970 | ||
| Thermodynamic characterization of the structural stability of the coiled-coil region of the bZIP transcription factor GCN4. | Q52395143 | ||
| Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2 | Q24563807 | ||
| Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
| CRM1 is an export receptor for leucine-rich nuclear export signals | Q27860453 | ||
| The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs | Q28131708 | ||
| Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity | Q28140993 | ||
| Cellular localisation and nuclear export of the human bZIP transcription factor TCF11 | Q28202272 | ||
| Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene | Q28204923 | ||
| The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm | Q28216217 | ||
| Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants | Q28218883 | ||
| Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element | Q28240487 | ||
| Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron | Q28261724 | ||
| Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin | Q28304365 | ||
| Nrf2 is essential for protection against acute pulmonary injury in mice | Q28343659 | ||
| Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene | Q28372162 | ||
| Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes | Q28593237 | ||
| Identification of a signal for rapid export of proteins from the nucleus | Q29547742 | ||
| CRM1 is responsible for intracellular transport mediated by the nuclear export signal | Q29547861 | ||
| Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice | Q29615438 | ||
| Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression | Q29615644 | ||
| Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers | Q29616503 | ||
| Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors | Q29616505 | ||
| Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription | Q29617066 | ||
| Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation | Q29618051 | ||
| NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development | Q29620011 | ||
| High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes | Q31783158 | ||
| Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells | Q31855259 | ||
| Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element | Q33901796 | ||
| Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups | Q34735149 | ||
| Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes | Q35708009 | ||
| Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay | Q36561338 | ||
| Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins | Q36688599 | ||
| On the mechanisms of induction of cancer-protective enzymes: a unifying proposal | Q37558012 | ||
| Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice. | Q38289583 | ||
| Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism | Q38308355 | ||
| Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. | Q38363758 | ||
| Crystals of glutamine synthetase from Escherichia coli | Q40348794 | ||
| Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome | Q40688004 | ||
| P433 | issue | 31 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 28430-28438 | |
| P577 | publication date | 2005-05-23 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif | |
| P478 | volume | 280 |
| Q37073162 | AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550 |
| Q33783238 | Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization |
| Q37241323 | Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis |
| Q28389419 | Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system |
| Q34344051 | Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics. |
| Q58790658 | Baicalin provides neuroprotection in traumatic brain injury mice model through Akt/Nrf2 pathway |
| Q28391506 | Basic principles and emerging concepts in the redox control of transcription factors |
| Q33576139 | Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response |
| Q39146703 | Characterization of pollen-expressed bZIP protein interactions and the role of ATbZIP18 in the male gametophyte. |
| Q33520215 | Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes |
| Q36846919 | Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease |
| Q28396785 | Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection |
| Q36477584 | Expression of Nrf2 in neurodegenerative diseases |
| Q28270020 | Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes |
| Q36944428 | Heterodimerization with small Maf proteins enhances nuclear retention of Nrf2 via masking the NESzip motif |
| Q27004438 | Hydrogen peroxide sensing, signaling and regulation of transcription factors |
| Q38553032 | KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity |
| Q28382872 | Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2 |
| Q28384271 | Mechanisms of Nrf2/Keap1-dependent phase II cytoprotective and detoxifying gene expression and potential cellular targets of chemopreventive isothiocyanates |
| Q37073173 | Molecular mechanisms of Nrf2-mediated antioxidant response |
| Q36512148 | Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. |
| Q35215048 | NOA1, a novel ClpXP substrate, takes an unexpected nuclear detour prior to mitochondrial import |
| Q46458284 | Nrf2 Activation as a Protective Feedback to Limit Cell Death in High Glucose-Exposed Cardiomyocytes |
| Q50726063 | Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain. |
| Q56395741 | Nuclear-resident RIG-I senses viral replication inducing antiviral immunity |
| Q64945936 | PML-Nuclear Bodies Regulate the Stability of the Fusion Protein Dendra2-Nrf2 in the Nucleus. |
| Q36610404 | Part of the series: from dietary antioxidants to regulators in cellular signaling and gene regulation. Sulforaphane and selenium, partners in adaptive response and prevention of cancer |
| Q54581515 | Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice. |
| Q28385642 | Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability |
| Q35230296 | Proteins as binding targets of isothiocyanates in cancer prevention |
| Q37756926 | Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: antioxidant coupled with antiinflammatory |
| Q27000878 | Regulation of Nrf2-Mediated Phase II Detoxification and Anti-oxidant Genes |
| Q42678633 | Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress |
| Q37023880 | Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis |
| Q37379750 | Repression of classical nuclear export by S-nitrosylation of CRM1. |
| Q28384783 | Stress-activated cap'n'collar transcription factors in aging and human disease |
| Q24298930 | Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling |
| Q37521075 | Targeting the Nrf2 pathway against cardiovascular disease |
| Q24812592 | The POU protein Oct-6 is a nucleocytoplasmic shuttling protein. |
| Q37848718 | The cytoprotective role of the Keap1-Nrf2 pathway |
| Q34682265 | The role of chalcones in suppression of NF-κB-mediated inflammation and cancer |
| Q34960760 | The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2. |
| Q35740930 | Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice |
| Q38211021 | bZIPs and WRKYs: two large transcription factor families executing two different functional strategies |
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