Rapid targeting of nuclear proteins to the cytoplasm

scientific article published in September 1997

Rapid targeting of nuclear proteins to the cytoplasm is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0960-9822(06)00290-9
P698PubMed publication ID9285717
P5875ResearchGate publication ID13934709

P2093author name stringCrabtree GR
Beals CR
Klemm JD
P2860cites workNuclear export of NF-ATc enhanced by glycogen synthase kinase-3Q24309262
Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 RevQ24568152
Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteinsQ24602548
A molecular mechanism for the effect of lithium on developmentQ24629067
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
NF-AT components define a family of transcription factors targeted in T-cell activationQ28114991
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAsQ28131708
A mammalian protein targeted by G1-arresting rapamycin-receptor complexQ28243712
Inositol trisphosphate and calcium signallingQ28262867
Nucleocytoplasmic transportQ28275907
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexesQ28277749
HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAsQ28289718
Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residueQ28367688
HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitroQ28508478
Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interactionQ28616185
Identification of a signal for rapid export of proteins from the nucleusQ29547742
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cellsQ29618245
Differential activation of transcription factors induced by Ca2+ response amplitude and durationQ29619010
Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cellsQ33764692
A general strategy for producing conditional alleles of Src-like tyrosine kinasesQ33871195
Signal transduction in T lymphocytes using a conditional allele of SosQ33871535
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycinQ33911404
Mutational definition of the human immunodeficiency virus type 1 Rev activation domain.Q34132236
Identification of a putative regulator of early T cell activation genesQ34171263
Controlling Signal Transduction with Synthetic LigandsQ34306937
Dimeric ligands define a role for transcriptional activation domains in reinitiationQ34391943
A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1.Q36237387
Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoterQ36362429
Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/cQ36550421
Characterization of the nuclear export signal of human T-cell lymphotropic virus type 1 Rex reveals that nuclear export is mediated by position-variable hydrophobic interactionsQ36562395
Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 geneQ38295828
Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoterQ40412449
Nuclear export signals and the fast track to the cytoplasmQ40459787
Protein translocation: nuclear export--out of the darkQ41010427
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppressionQ41157105
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin AQ46979889
Nuclear export of proteins: the role of nuclear retention.Q49136533
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)638-644
P577publication date1997-09-01
P1433published inCurrent BiologyQ1144851
P1476titleRapid targeting of nuclear proteins to the cytoplasm
P478volume7

Reverse relations

cites work (P2860)
Q28216943A constitutively nuclear form of NFATx shows efficient transactivation activity and induces differentiation of CD4(+)CD8(+) T cells
Q30454343A cytosolic activity distinct from crm1 mediates nuclear export of protein kinase inhibitor in permeabilized cells.
Q40331048A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.
Q28613530A second calcineurin binding site on the NFAT regulatory domain
Q35586564Ca2+/calcineurin signalling in cells of the immune system
Q50267304Chemical genetics resulting from a passion for synthetic organic chemistry.
Q52431090Chemically induced proximity in biology and medicine.
Q28831144Conditionally controlling nuclear trafficking in yeast by chemical-induced protein dimerization
Q42741779Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas
Q34707706DNA binding sites target nuclear NFATc1 to heterochromatin regions in adult skeletal muscle fibers
Q36322886Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore
Q24339552Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis
Q35893955Evolutionary relationships among Rel domains indicate functional diversification by recombination
Q35880169Exploiting protein destruction for constructive use.
Q28139459Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT
Q31527478Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc
Q38884286Go in! Go out! Inducible control of nuclear localization
Q35823256Import and export of nuclear proteins: focus on the nucleocytoplasmic movements of two different species of mammalian estrogen receptor
Q28215961In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap
Q22003948Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm
Q24554335Integration of calcium and cyclic AMP signaling pathways by 14-3-3
Q57833199Judging a Protein by More Than Its Name: GSK-3
Q35076704Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation
Q33906170Manipulating immune responses with immunosuppressive agents that target NFAT.
Q37983428Many mechanisms, one entrance: membrane protein translocation into the nucleus
Q36995482Modeling renal progenitors - defining the niche
Q34282353Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling.
Q91971879Multispecific drugs herald a new era of biopharmaceutical innovation
Q50495025NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins.
Q28216151NFAT signaling: choreographing the social lives of cells
Q35053197Novel chemical genetic approaches to the discovery of signal transduction inhibitors
Q41961089Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro
Q38411212Nup214 is required for CRM1-dependent nuclear protein export in vivo
Q28238313Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export
Q34279371Partners in transcription: NFAT and AP-1.
Q28140841Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro
Q40701095Protein kinase A negatively modulates the nuclear accumulation of NF-ATc1 by priming for subsequent phosphorylation by glycogen synthase kinase-3.
Q38009985Protein translocation as a tool: The current rapamycin story.
Q37477637Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export
Q33937097Regulation of nuclear import and export.
Q36287472Regulation of phospholipase C-gamma2 networks in B lymphocytes
Q50703706Regulation of the nuclear export of the transcription factor NFATc1 by protein kinases after slow fibre type electrical stimulation of adult mouse skeletal muscle fibres.
Q34170925Signaling through calcium, calcineurin, and NF-AT in lymphocyte activation and development.
Q77483314Signalling into the T-cell nucleus: NFAT regulation
Q28258881Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment
Q35775678Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells.
Q77452219Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins
Q24538664The NS2 proteins of parvovirus minute virus of mice are required for efficient nuclear egress of progeny virions in mouse cells.
Q33957684The cytoskeleton in lymphocyte signaling
Q33277804The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain
Q34066446The role of NF-AT transcription factors in T cell activation and differentiation
Q34401921Transcriptional regulation of hemopoiesis
Q29615611Transport into and out of the nucleus
Q46217445Wheat cryptochromes: subcellular localization and involvement in photomorphogenesis and osmotic stress responses.

Search more.