SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex

scientific article

SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.140.3.499
P3181OpenCitations bibliographic resource ID1426973
P932PMC publication ID2140169
P698PubMed publication ID9456312

P50authorGünter BlobelQ60108
P2093author name stringJ Wu
M J Matunis
P2860cites workA nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathwayQ24309825
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complexQ24310068
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complexQ24316128
Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transportQ24316235
Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1Q24316332
A giant nucleopore protein that binds Ran/TC4Q24317506
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2Q24317523
Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24Q24561817
Identification of different roles for RanGDP and RanGTP in nuclear protein importQ24561933
Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporinsQ24563707
RanGAP1 induces GTPase activity of nuclear Ras-related RanQ24564044
The Ran/TC4 GTPase-binding domain: identification by expression cloning and characterization of a conserved sequence motifQ24564692
Conjugates of ubiquitin cross-reactive protein distribute in a cytoskeletal patternQ24607385
Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processingQ24652656
A nuclear localization domain in the hnRNP A1 proteinQ24672627
CRM1 is an export receptor for leucine-rich nuclear export signalsQ27860453
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene productQ27860841
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3pQ27930030
Ubiquitin-dependent protein degradationQ27931143
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimerQ27933072
Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating proteinQ27933997
Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclinsQ27937265
Exportin 1 (Crm1p) is an essential nuclear export factorQ27939696
UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteinsQ28115876
PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemiaQ28115998
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAsQ28131708
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporinsQ28131733
Preferential modification of nuclear proteins by a novel ubiquitin-like moleculeQ28238897
Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4Q28257159
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activityQ28276063
HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAsQ28289718
Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrinQ28295931
Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid systemQ28296868
Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich regionQ28566768
Identification of a signal for rapid export of proteins from the nucleusQ29547742
A short amino acid sequence able to specify nuclear locationQ29547781
Nucleocytoplasmic transport: signals, mechanisms and regulationQ29547904
A 26 S protease subunit that binds ubiquitin conjugatesQ29614362
Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-CQ29616337
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosisQ29617390
The GTP-binding protein Ran/TC4 is required for protein import into the nucleusQ29620192
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factorQ29620193
Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelopeQ29622845
Conjugation of the 15-kDa interferon-induced ubiquitin homolog is distinct from that of ubiquitinQ34370290
Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein geneQ34379548
Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitinQ34396930
RanBP2 associates with Ubc9p and a modified form of RanGAP1Q36105014
Nucleocytoplasmic transport of macromoleculesQ36574246
Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genesQ36769701
Identification of the human c-myc protein nuclear translocation signalQ36846194
Physical change in cytoplasmic messenger ribonucleoproteins in cells treated with inhibitors of mRNA transcriptionQ36941894
NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complexQ40365381
Roles of ubiquitinylation in proteolysis and cellular regulationQ40926065
The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.Q41076100
Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificitiesQ41079130
The small nuclear GTPase Ran: how much does it run?Q41147096
Role of the nuclear transport factor p10 in nuclear importQ48064951
Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein importQ49486091
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectnuclear pore cytoplasmic filamentsQ21112340
P304page(s)499-509
P577publication date1998-02-09
P1433published inJournal of Cell BiologyQ1524550
P1476titleSUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex
P478volume140

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Q28140711Yeast two-hybrid system identifies the ubiquitin-conjugating enzyme mUbc9 as a potential partner of mouse Dac
Q36403109Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation
Q24306219ZNF198, a zinc finger protein rearranged in myeloproliferative disease, localizes to the PML nuclear bodies and interacts with SUMO-1 and PML
Q37131508p53 SUMOylation promotes its nuclear export by facilitating its release from the nuclear export receptor CRM1

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