The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

scientific article

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/16.18.5509
P3181OpenCitations bibliographic resource ID1426968
P932PMC publication ID1170183
P698PubMed publication ID9312010
P5875ResearchGate publication ID13910230

P50authorGünter BlobelQ60108
P2093author name stringR J Dohmen
E S Johnson
I Schwienhorst
P2860cites workAPP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor proteinQ24310276
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A multiubiquitin chain is confined to specific lysine in a targeted short-lived proteinQ29547884
Two nuclear mutations that block mitochondrial protein import in yeastQ29618080
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascadeQ29620459
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The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteinsQ34248463
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The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological functionQ36828110
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Efficient random mutagenesis method with adjustable mutation frequency by use of PCR and dITP.Q40405311
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Ubiquitin adenylate: structure and role in ubiquitin activationQ70168206
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Fusion of GAL4-VP16 to a steroid-binding domain provides a tool for gratuitous induction of galactose-responsive genes in yeastQ72921343
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectE1 ubiquitin-activating protein UBA2 YDR390CQ27547786
E1 ubiquitin-activating protein AOS1 YPR180WQ27548725
SUMO family protein SMT3 YDR510WQ27549524
P304page(s)5509-5519
P577publication date1997-09-01
P1433published inThe EMBO JournalQ1278554
P1476titleThe ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer
P478volume16

Reverse relations

cites work (P2860)
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Q27931553SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II
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Q31016120SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52.
Q38132691SUMO rules: regulatory concepts and their implication in neurologic functions.
Q33939449SUMO, ubiquitin's mysterious cousin
Q34400369SUMO--a post-translational modification with therapeutic potential?
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Q44221557SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin
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Q41981980SUMO-1 modification alters ADAR1 editing activity
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Q40868752SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
Q48596243SUMO-1 plays crucial roles for spindle organization, chromosome congression, and chromosome segregation during mouse oocyte meiotic maturation
Q35440501SUMO-mimicking peptides inhibiting protein SUMOylation
Q38583743SUMO-regulated transcription: challenging the dogma
Q33765355SUMO/sentrin: protein modifiers regulating important cellular functions
Q28243325SUMO: a history of modification
Q35362103SUMOhunt: Combining Spatial Staging between Lysine and SUMO with Random Forests to Predict SUMOylation.
Q37425378SUMOylation and deSUMOylation at a glance
Q33649471SUMOylation in Giardia lamblia: A Conserved Post-Translational Modification in One of the Earliest Divergent Eukaryotes
Q90114163SUMOylation in Human Pathogenic Fungi: Role in Physiology and Virulence
Q41809986SUMOylation in Trypanosoma brucei
Q27027291SUMOylation in control of accurate chromosome segregation during mitosis
Q35031726SUMOylation is developmentally regulated and required for cell pairing during conjugation in Tetrahymena thermophila
Q52597096SUMOylation is required for fungal development and pathogenicity in the rice blast fungus Magnaporthe oryzae.
Q56908930SUMOylation modulates transcriptional repression by TRPS1
Q37313069SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination.
Q40796318SUMOylation of Wor1 by a novel SUMO E3 ligase controls cell fate in Candida albicans
Q35610633SUMOylation pathway in Trypanosoma cruzi: functional characterization and proteomic analysis of target proteins
Q27932790SUMOylation regulates the SNF1 protein kinase
Q39412884SUMOylation regulates the intracellular fate of ZO-2.
Q26776081SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer
Q35939900Small ubiquitin-like modifier (SUMO) modification of E1 Cys domain inhibits E1 Cys domain enzymatic activity
Q40319470Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein
Q30419271Small ubiquitin-like modifier (SUMO) modification of zinc finger protein 131 potentiates its negative effect on estrogen signaling
Q37392596Small ubiquitin-like modifiers in cellular malignancy and metastasis
Q43252764Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification
Q42717633Small ubiquitin-related modifier ligase activity of Mms21 is required for maintenance of chromosome integrity during the unperturbed mitotic cell division cycle in Saccharomyces cerevisiae
Q43002306Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor
Q34551647Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins
Q24291008Stabilization and activation of p53 by the coactivator protein TAFII31
Q40666794Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway
Q36178621Stimulation of in vitro sumoylation by Slx5-Slx8: evidence for a functional interaction with the SUMO pathway
Q24338548Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1
Q39107046Sub-cellular localization specific SUMOylation in the heart
Q51137597Sumo Modification of Ion Channels
Q37413787Sumoylation and human disease pathogenesis
Q27933175Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution
Q34454789Sumoylation in Aspergillus nidulans: sumO inactivation, overexpression and live-cell imaging
Q24675969Sumoylation is involved in beta-catenin-dependent activation of Tcf-4
Q44253301Sumoylation of Pdx1 is associated with its nuclear localization and insulin gene activation
Q36466624Sumoylation of SAE2 C terminus regulates SAE nuclear localization
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Q36788236The Arabidopsis cullin AtCUL1 is modified by the ubiquitin-related protein RUB1.
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Q24296256The DNA topoisomerase I binding protein topors as a novel cellular target for SUMO-1 modification: characterization of domains necessary for subcellular localization and sumolation
Q95815063The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9
Q54582549The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.
Q91439426The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε
Q47095192The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.
Q43111197The SUMO conjugation pathway in Populus: genomic analysis, tissue-specific and inducible SUMOylation and in vitro de-SUMOylation
Q44564184The SUMO isopeptidase Ulp2 prevents accumulation of SUMO chains in yeast
Q35188352The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p
Q36281573The Ubp6 family of deubiquitinating enzymes contains a ubiquitin-like domain: SUb.
Q41670103The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).
Q34695640The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases
Q34081793The molecular determinants of NEDD8 specific recognition by human SENP8.
Q37971572The natural history of ubiquitin and ubiquitin-related domains
Q28616490The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers
Q28115324The polycomb protein Pc2 is a SUMO E3
Q40311432The promyelocytic leukemia protein stimulates SUMO conjugation in yeast.
Q24678032The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
Q36619437The role of SUMO in chromosome segregation
Q27766354The rub family of ubiquitin-like proteins. Crystal structure of Arabidopsis rub1 and expression of multiple rubs in Arabidopsis
Q36665786The small ubiquitin-like modifier (SUMO) and SUMO-conjugating system of Chlamydomonas reinhardtii
Q43203251The small ubiquitin-like modifier (SUMO) is essential in cell cycle regulation in Trypanosoma brucei.
Q44249813The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.
Q37011372The spindle positioning protein Kar9p interacts with the sumoylation machinery in Saccharomyces cerevisiae
Q27642844The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1
Q33892794The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines
Q28140478The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis
Q27934272The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme
Q29619270The ubiquitin-proteasome pathway: on protein death and cell life
Q24292709The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction
Q27936786The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein
Q28268988Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo
Q27935525Two-hybrid analysis of the Saccharomyces cerevisiae 26S proteasome
Q36724992UHRF2, a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier E3 ligase for zinc finger protein 131.
Q40174655Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation
Q41762379Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation
Q27930030Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p
Q24647626Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways
Q35691524Ubiquitin-like protein activation.
Q33901542Ubiquitin-like proteins: new wines in new bottles
Q27625224Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast
Q27930209Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins
Q37169166Unfoldase-mediated protein translocation through an α-hemolysin nanopore
Q27932517Urmylation: A Ubiquitin-like Pathway that Functions during Invasive Growth and Budding in Yeast
Q34638636Versatile protein tag, SUMO: its enzymology and biological function
Q34420675Viral interaction with the host cell sumoylation system
Q38047618WITHDRAWN: Protein sumoylation and human diseases
Q28563890Wss1 metalloprotease partners with Cdc48/Doa1 in processing genotoxic SUMO conjugates
Q60510247XSUMO-1 is required for normal mesoderm induction and axis elongation during earlyXenopus development
Q28267980Yeast PIAS-type Ull1/Siz1 is composed of SUMO ligase and regulatory domains
Q27935103Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates
Q27931053Yeast tom1 mutant exhibits pleiotropic defects in nuclear division, maintenance of nuclear structure and nucleocytoplasmic transport at high temperatures

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