| scholarly article | Q13442814 |
| P50 | author | Ismail H. Ismail | Q55459223 |
| P2093 | author name string | Jean-Yves Masson | |
| Guy G Poirier | |||
| Jean-Philippe Gagné | |||
| Michael J Hendzel | |||
| Darin McDonald | |||
| Zhizhong Xu | |||
| Marie-Christine Caron | |||
| P2860 | cites work | In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2 | Q22008717 |
| Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1 | Q22009137 | ||
| Interplay between human DNA repair proteins at a unique double-strand break in vivo | Q24300377 | ||
| RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
| RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage | Q24309181 | ||
| RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins | Q24309287 | ||
| PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies | Q24599898 | ||
| Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications | Q24608343 | ||
| Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks | Q24608599 | ||
| BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair | Q24632998 | ||
| BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair | Q24634217 | ||
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
| Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27 | Q24672052 | ||
| Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains | Q27641772 | ||
| Structure determination of the small ubiquitin-related modifier SUMO-1 | Q27760157 | ||
| The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer | Q27933072 | ||
| The nucleoporin RanBP2 has SUMO1 E3 ligase activity | Q28115025 | ||
| The polycomb protein Pc2 is a SUMO E3 | Q28115324 | ||
| Role of histone H3 lysine 27 methylation in Polycomb-group silencing | Q28131795 | ||
| Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex | Q28142407 | ||
| SUMO: a history of modification | Q28243325 | ||
| Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene | Q28505536 | ||
| Protein modification by SUMO | Q29547919 | ||
| Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences | Q30484141 | ||
| A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins | Q30760383 | ||
| SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization | Q33195747 | ||
| PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites | Q33306325 | ||
| Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality | Q33580247 | ||
| A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage | Q33715275 | ||
| SUMOylation and de-SUMOylation in response to DNA damage. | Q33870712 | ||
| Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin | Q33952737 | ||
| Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein | Q33986097 | ||
| Bmi1 regulates mitochondrial function and the DNA damage response pathway | Q34017298 | ||
| Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness". | Q34166507 | ||
| Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes | Q34563280 | ||
| An anticlastogenic function for the Polycomb Group gene Bmi1. | Q34750024 | ||
| Monoubiquitination of H2AX protein regulates DNA damage response signaling | Q35150282 | ||
| PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development | Q35848522 | ||
| Signalling pathways and the regulation of SUMO modification | Q37010217 | ||
| The gamma-H2A.X: is it just a surrogate marker of double-strand breaks or much more? | Q37038673 | ||
| Regulation of DNA repair throughout the cell cycle | Q37088926 | ||
| Regulatory ubiquitylation in response to DNA double-strand breaks | Q37397281 | ||
| Principles of ubiquitin and SUMO modifications in DNA repair. | Q37424808 | ||
| Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer | Q37629613 | ||
| The ubiquitous role of ubiquitin in the DNA damage response | Q37807639 | ||
| SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression | Q37820200 | ||
| PARP-1 Regulates Chromatin Structure and Transcription through a KDM5B-Dependent Pathway | Q39657013 | ||
| BMI1 Confers Radioresistance to Normal and Cancerous Neural Stem Cells through Recruitment of the DNA Damage Response Machinery | Q39674232 | ||
| PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. | Q39695522 | ||
| The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. | Q39762239 | ||
| Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents | Q40146768 | ||
| Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. | Q40224191 | ||
| Recombinant ATM protein complements the cellular A-T phenotype | Q41099853 | ||
| Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line | Q41368190 | ||
| Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase | Q46185029 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA damage | Q5205747 |
| P304 | page(s) | 5497-5510 | |
| P577 | publication date | 2012-03-08 | |
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage | |
| P478 | volume | 40 |
| Q38161767 | A new world of Polycombs: unexpected partnerships and emerging functions |
| Q51287846 | A novel approach to the analysis of SUMOylation with the independent use of trypsin and elastase digestion followed by database searching utilising consecutive residue addition to lysine. |
| Q37168494 | A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks |
| Q57111907 | B lymphoma Moloney murine leukemia virus insertion region 1: An oncogenic mediator in prostate cancer |
| Q37686453 | BMI1, a new target of CK2α |
| Q26750676 | BMI1: A Biomarker of Hematologic Malignancies |
| Q36121000 | Bmi-1: At the crossroads of physiological and pathological biology |
| Q37517517 | CBX Chromodomain Inhibition Enhances Chemotherapy Response in Glioblastoma Multiforme. |
| Q50296471 | CBX4 SUMOylates BMI1 in PRC1 with SUMO1 |
| Q89952902 | CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma |
| Q47783371 | Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides |
| Q58744047 | Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency |
| Q38355251 | Chromobox Homolog 4 is Positively Correlated to Tumor Growth, Survival and Activation of HIF-1α Signaling in Human Osteosarcoma under Normoxic Condition |
| Q39110553 | Chromobox homolog 4 is correlated with prognosis and tumor cell growth in hepatocellular carcinoma |
| Q38867022 | Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity |
| Q37578232 | Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos |
| Q41107828 | DNA end resection requires constitutive sumoylation of CtIP by CBX4. |
| Q27865266 | Detecting endogenous SUMO targets in mammalian cells and tissues |
| Q39034062 | Developmental transcriptional regulation by SUMOylation, an evolving field |
| Q90101476 | Dynamic methylome of internal mRNA N7-methylguanosine and its regulatory role in translation |
| Q34298587 | Ehrlichia chaffeensis exploits host SUMOylation pathways to mediate effector-host interactions and promote intracellular survival |
| Q33826899 | Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteins |
| Q38970763 | Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome. |
| Q42415955 | Implication of SUMO E3 ligases in nucleotide excision repair |
| Q26752447 | Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress |
| Q37166395 | Knockdown BMI1 expression inhibits proliferation and invasion in human bladder cancer T24 cells |
| Q99632932 | Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome |
| Q47154064 | Meta-analysis of DNA double-strand break response kinetics |
| Q92068419 | MicroRNA-497-5p Induces Cell Cycle Arrest Of Cervical Cancer Cells In S Phase By Targeting CBX4 |
| Q46156138 | Mitochondrial BMI1 maintains bioenergetic homeostasis in cells |
| Q39355026 | Molecular Basis for K63-Linked Ubiquitination Processes in Double-Strand DNA Break Repair: A Focus on Kinetics and Dynamics. |
| Q38024191 | New readers and interpretations of poly(ADP-ribosyl)ation |
| Q41517212 | PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks |
| Q38655716 | PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining. |
| Q33635465 | PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways. |
| Q34786561 | Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer |
| Q26801380 | Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications |
| Q102369118 | Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes |
| Q42017606 | Polycomb repressive complex 2 contributes to DNA double-strand break repair |
| Q34157687 | Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection |
| Q46709248 | RNA sequencing supports distinct reactive oxygen species-mediated pathways of apoptosis by high and low size mass fractions of Bay leaf (Lauris nobilis) in HT-29 cells |
| Q38095917 | Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair |
| Q38841261 | Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers. |
| Q38069879 | Reprogramming cellular events by poly(ADP-ribose)-binding proteins |
| Q35212226 | Role of polycomb group proteins in the DNA damage response--a reassessment |
| Q37278125 | SENP1 Is a Crucial Regulator for Cell Senescence through DeSUMOylation of Bmi1. |
| Q52757703 | SUMO, a small, but powerful, regulator of double-strand break repair. |
| Q28086764 | SUMO-mediated regulation of DNA damage repair and responses |
| Q39106335 | SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase |
| Q38656328 | Spatiotemporal regulation of posttranslational modifications in the DNA damage response |
| Q38219978 | Sumoylation and the DNA damage response |
| Q39062063 | The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair. |
| Q52691495 | The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia. |
| Q28115442 | The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice |
| Q39768470 | The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51. |
| Q64077175 | The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms |
| Q38056099 | The emerging role of Polycomb repressors in the response to DNA damage |
| Q90109546 | Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency |
| Q89768702 | Ubiquitin and ubiquitin-like molecules in DNA double strand break repair |
| Q55457011 | Ubiquitin-specific protease 22 acts as an oncoprotein to maintain glioma malignancy through deubiquitinating B cell-specific Moloney murine leukemia virus integration site 1 for stabilization. |
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