scholarly article | Q13442814 |
P50 | author | Stephen P Jackson | Q37392575 |
Sophie E Polo | Q50199081 | ||
Yaron Galanty | Q57410063 | ||
P2093 | author name string | Julia Coates | |
Rimma Belotserkovskaya | |||
Kyle M Miller | |||
P2860 | cites work | MDC1 is a mediator of the mammalian DNA damage checkpoint | Q24296229 |
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 | ||
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage | Q24309181 | ||
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins | Q24309287 | ||
BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair | Q24310221 | ||
Human MMS21/NSE2 is a SUMO ligase required for DNA repair | Q24529887 | ||
Human CtIP promotes DNA end resection | Q24646062 | ||
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
SAP - a putative DNA-binding motif involved in chromosomal organization | Q28145637 | ||
SUMO: a history of modification | Q28243325 | ||
MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes | Q28274268 | ||
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals | Q28292900 | ||
Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3 | Q28509725 | ||
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells | Q28511551 | ||
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM | Q29614843 | ||
Good timing in the cell cycle for precise DNA repair by BRCA1. | Q33221793 | ||
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage | Q34179079 | ||
A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. | Q34619746 | ||
Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation | Q35880280 | ||
Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair | Q36510700 | ||
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability | Q36602569 | ||
A New Method for Introducing Double-Strand Breaks into Cellular DNA | Q36695831 | ||
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage | Q36696336 | ||
Chromatin dynamics and the preservation of genetic information | Q36854289 | ||
Principles of ubiquitin and SUMO modifications in DNA repair. | Q37424808 | ||
An additional role for SUMO in ubiquitin-mediated proteolysis | Q37498263 | ||
Cell biology: SUMO. | Q43519621 | ||
P433 | issue | 7275 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 935-9 | |
P577 | publication date | 2009-12-17 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks | |
P478 | volume | 462 |
Q24600350 | 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers |
Q37713592 | 53BP1, BRCA1, and the choice between recombination and end joining at DNA double-strand breaks |
Q35483796 | A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency |
Q34774721 | A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes |
Q39583866 | A comprehensive compilation of SUMO proteomics. |
Q33698648 | A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy |
Q36372110 | A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint |
Q47099792 | A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis. |
Q36775152 | A new MCM modification cycle regulates DNA replication initiation |
Q38256644 | A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair |
Q38084210 | A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer |
Q33840749 | A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients |
Q35742838 | A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20. |
Q28477120 | A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence |
Q47347231 | Acetylation of 53BP1 dictates the DNA double strand break repair pathway. |
Q42326367 | Adenovirus regulates sumoylation of Mre11-Rad50-Nbs1 components through a paralog-specific mechanism |
Q48411490 | An E2-guided E3 Screen Identifies the RNF17-UBE2U Pair as Regulator of the Radiosensitivity, Immunodeficiency, Dysmorphic Features, and Learning Difficulties (RIDDLE) Syndrome Protein RNF168. |
Q33947105 | An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress |
Q42221274 | Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4. |
Q34985577 | BLM SUMOylation regulates ssDNA accumulation at stalled replication forks |
Q30525067 | BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair |
Q34252163 | BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies |
Q34188958 | CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage |
Q49685857 | Caught with One's Zinc Fingers in the Genome Integrity Cookie Jar. |
Q35896405 | Cells and Stripes: A novel quantitative photo-manipulation technique |
Q35854193 | Changing the ubiquitin landscape during viral manipulation of the DNA damage response |
Q26744843 | Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture |
Q37826623 | Chromatin dynamics and the repair of DNA double strand breaks |
Q36012981 | Chromatin dynamics in DNA double-strand break repair |
Q33817223 | Comprehensive identification of SUMO2/3 targets and their dynamics during mitosis |
Q38459546 | Computational genomic analysis of PARK7 interactome reveals high BBS1 gene expression as a prognostic factor favoring survival in malignant pleural mesothelioma. |
Q35050661 | Concerted action of the ubiquitin-fusion degradation protein 1 (Ufd1) and Sumo-targeted ubiquitin ligases (STUbLs) in the DNA-damage response |
Q30597332 | Confinement and deformation of single cells and their nuclei inside size-adapted microtubes |
Q37813020 | Connecting the Dots: Interplay between Ubiquitylation and SUMOylation at DNA Double-Strand Breaks |
Q26765420 | Cooperativity of the SUMO and Ubiquitin Pathways in Genome Stability |
Q35971460 | Coordinate to guard: crosstalk of phosphorylation, sumoylation, and ubiquitylation in DNA damage response. |
Q27023465 | Crosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repair |
Q43069093 | Crystal structure and SUMO binding of Slx1-Slx4 complex |
Q38390031 | Customized chemotherapy in metastatic non-small cell lung cancer (NSCLC) |
Q35740310 | DNA break-induced sumoylation is enabled by collaboration between a SUMO ligase and the ssDNA-binding complex RPA. |
Q33844504 | DNA damage and lamins |
Q78177428 | DNA damage response and repair in perspective: Aedes aegypti, Drosophila melanogaster and Homo sapiens. |
Q38134064 | DNA damage sensing by the ATM and ATR kinases. |
Q37995692 | DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. |
Q39309267 | DNA damage-induced heterogeneous nuclear ribonucleoprotein K sumoylation regulates p53 transcriptional activation |
Q24314513 | DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger |
Q34360500 | DNA double-strand break signaling and human disorders |
Q41107828 | DNA end resection requires constitutive sumoylation of CtIP by CBX4. |
Q36956378 | DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy |
Q55052466 | DNA repair: A heavyweight joins the fray. |
Q55052925 | DNA repair: Decision at the break point. |
Q50995887 | DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair. |
Q92936521 | DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program |
Q33871913 | Damage site chromatin: open or closed? |
Q38091465 | Decoding the SUMO signal |
Q37871126 | Degradation-linked ubiquitin signal and proteasome are integral components of DNA double strand break repair: New perspectives for anti-cancer therapy. |
Q36333328 | Depletion of UBC9 Causes Nuclear Defects during the Vegetative and Sexual Life Cycles in Tetrahymena thermophila |
Q41462937 | Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface |
Q33623702 | Development and validation of a method for profiling post-translational modification activities using protein microarrays. |
Q33682993 | Differential effect of MMSET mRNA levels on survival to first-line FOLFOX and second-line docetaxel in gastric cancer |
Q36343157 | Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms |
Q35603613 | Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells |
Q26830517 | Double-strand break repair on sex chromosomes: challenges during male meiotic prophase |
Q34391068 | Double-strand break repair: 53BP1 comes into focus |
Q24608343 | Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications |
Q47136888 | Dynamics of RIF1 SUMOylation is regulated by PIAS4 in the maintenance of Genomic Stability |
Q38556007 | Emergence and evolutionary analysis of the human DDR network: implications in comparative genomics and downstream analyses |
Q24607287 | Epigenetic modifications in double-strand break DNA damage signaling and repair |
Q33826899 | Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteins |
Q55011560 | Epigenomic Modifications Mediating Antibody Maturation. |
Q35115031 | Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase |
Q39982714 | Exonuclease containment by SUMO plus ubiquitin |
Q43070544 | Expanding NFκB and SUMO ties |
Q33979535 | Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells |
Q35191041 | Expression profiling and pathway analysis of Krüppel-like factor 4 in mouse embryonic fibroblasts |
Q42142499 | Extensive DNA damage-induced sumoylation contributes to replication and repair and acts in addition to the mec1 checkpoint |
Q38871644 | Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage |
Q44951464 | Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer. |
Q36963162 | Focus on histone variant H2AX: to be or not to be. |
Q38221703 | Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress. |
Q39135992 | Functions of SUMO in the Maintenance of Genome Stability |
Q28831346 | G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status |
Q37778386 | Genomes in Conflict: Maintaining Genome Integrity During Virus Infection |
Q50287323 | HERC2 and PIAS4 are recruited to DNA DSBs |
Q28563892 | Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid |
Q37881417 | Histone tails: Directing the chromatin response to DNA damage |
Q36106937 | Homologous recombination and its regulation |
Q35227435 | Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia |
Q26752451 | How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway |
Q39662092 | Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining |
Q24312250 | Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks |
Q48126439 | Hypoxia Differentially Modulates the Genomic Stability of Clinical-Grade ADSCs and BM-MSCs in Long-Term Culture |
Q36347178 | ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanism |
Q63384140 | ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks |
Q35870845 | Identification of RNF168 as a PML nuclear body regulator |
Q44410005 | Identification of a molecular recognition feature in the E1A oncoprotein that binds the SUMO conjugase UBC9 and likely interferes with polySUMOylation. |
Q34512472 | Identification of novel interacting partners of Sirtuin6. |
Q37861028 | Inherited mutations in breast cancer genes--risk and response |
Q26752447 | Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress |
Q90424233 | Intricate SUMO-based control of the homologous recombination machinery |
Q36917433 | It takes two to tango: Ubiquitin and SUMO in the DNA damage response |
Q57283586 | Local activation of mammalian separase in interphase promotes double-strand break repair and prevents oncogenic transformation |
Q38747471 | Localisation of Nup153 and SENP1 to nuclear pore complexes is required for 53BP1-mediated DNA double-strand break repair |
Q39761629 | Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage |
Q34879712 | MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells |
Q111442218 | Mechanism and function of DNA replication‐independent DNA‐protein crosslink repair via the SUMO‐RNF4 pathway |
Q39355026 | Molecular Basis for K63-Linked Ubiquitination Processes in Double-Strand DNA Break Repair: A Focus on Kinetics and Dynamics. |
Q39676703 | Molecular Basis for Phosphorylation-dependent SUMO Recognition by the DNA Repair Protein RAP80. |
Q33840504 | Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma |
Q37734700 | More modifiers move on DNA damage |
Q37942059 | More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance |
Q33930358 | Mutations in the BRCT binding site of BRCA1 result in hyper-recombination |
Q38392308 | NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress. |
Q28080823 | NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma |
Q34195476 | NMR metabolomic profiling reveals new roles of SUMOylation in DNA damage response |
Q38042455 | New insights into pre-mRNA processing factor 19: A multi-faceted protein in humans |
Q35025388 | New tools to study DNA double-strand break repair pathway choice |
Q24296739 | Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 |
Q34898909 | Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance |
Q38789307 | Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response |
Q39717764 | Novel antibody derivatives for proteome and high-content analysis |
Q35347865 | Nuclear initiated NF-κB signaling: NEMO and ATM take center stage |
Q61816601 | On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation |
Q34043691 | On the road with WRAP53β: guardian of Cajal bodies and genome integrity |
Q89636895 | PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1 |
Q38655716 | PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining. |
Q36984471 | PIAS1 Promotes Lymphomagenesis through MYC Upregulation |
Q35068026 | PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells |
Q36896806 | PIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer. |
Q50296414 | PIAS1,4 SUMOylates BRCA1 with SUMO1 |
Q50296416 | PIAS1,4 SUMOylates BRCA1 with SUMO2,3 |
Q42493887 | PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer |
Q24609002 | PIAS3 promotes homology‑directed repair and distal non‑homologous end joining |
Q50296403 | PIAS4 SUMOylates TP53BP1 with SUMO1 |
Q39321762 | PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy. |
Q38092800 | PML Degradation: Multiple Ways to Eliminate PML. |
Q55110010 | Pathology of hereditary breast cancer. |
Q89834460 | Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids |
Q42721929 | Pias1 is essential for erythroid and vascular development in the mouse embryo. |
Q45974271 | Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice. |
Q37471156 | Polymorphism of UBC9 gene encoding the SUMO-E2-conjugating enzyme and breast cancer risk. |
Q27009492 | Predictive models for customizing chemotherapy in advanced non-small cell lung cancer (NSCLC) |
Q28590257 | Protein inhibitor of activated STAT 1 (PIAS1) is identified as the SUMO E3 ligase of CCAAT/enhancer-binding protein β (C/EBPβ) during adipogenesis |
Q47113405 | Proteome Stability as a Key Factor of Genome Integrity |
Q39201092 | Proteome-wide identification of SUMO2 modification sites |
Q34991427 | Proteomic analysis of ubiquitin-like posttranslational modifications induced by the adenovirus E4-ORF3 protein |
Q43101547 | Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites |
Q39451819 | Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924. |
Q39417081 | RAP80, ubiquitin and SUMO in the DNA damage response. |
Q50053066 | RAS GTPases are modified by SUMOylation. |
Q36677932 | RNF111-dependent neddylation activates DNA damage-induced ubiquitination |
Q37224293 | RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment |
Q24294332 | RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response |
Q36603136 | RNF4 is required for DNA double-strand break repair in vivo |
Q34290557 | RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair |
Q34040089 | RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage. |
Q35409078 | RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway |
Q24306486 | RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites |
Q37396238 | Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. |
Q36127031 | Rap80 protein recruitment to DNA double-strand breaks requires binding to both small ubiquitin-like modifier (SUMO) and ubiquitin conjugates |
Q58773614 | Rare Genetic Diseases with Defects in DNA Repair: Opportunities and Challenges in Orphan Drug Development for Targeted Cancer Therapy |
Q39814876 | Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway |
Q38095917 | Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair |
Q26752453 | Real Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand Breaks |
Q38771420 | Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress |
Q35358319 | Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair |
Q38841261 | Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers. |
Q33655773 | Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. |
Q42157334 | Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair |
Q34899616 | Regulation of REGγ cellular distribution and function by SUMO modification |
Q33966065 | Regulation of homologous recombination in eukaryotes |
Q30409858 | Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1. |
Q37137813 | Regulation of the DNA damage response on male meiotic sex chromosomes |
Q38995558 | Relocalization of DNA lesions to the nuclear pore complex |
Q46063214 | Repair Scaffolding Reaches New Heights at Blocked Replication Forks |
Q27012688 | Repair of strand breaks by homologous recombination |
Q34854577 | Replication stress induces 53BP1-containing OPT domains in G1 cells |
Q26777328 | Roles for SUMO in pre-mRNA processing |
Q42143254 | SETX sumoylation: A link between DNA damage and RNA surveillance disrupted in AOA2. |
Q39858269 | SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence |
Q39108925 | SUMO and the robustness of cancer |
Q41983297 | SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function. |
Q47388205 | SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites |
Q33967953 | SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes |
Q35245641 | SUMO proteomics to decipher the SUMO-modified proteome regulated by various diseases |
Q38132691 | SUMO rules: regulatory concepts and their implication in neurologic functions. |
Q52757703 | SUMO, a small, but powerful, regulator of double-strand break repair. |
Q41836116 | SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. |
Q58803049 | SUMO-Mediated Regulation of Nuclear Functions and Signaling Processes |
Q28086764 | SUMO-mediated regulation of DNA damage repair and responses |
Q28594151 | SUMO-specific protease 2 in Mdm2-mediated regulation of p53 |
Q28569714 | SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage |
Q39598389 | SUMO2 and SUMO3 transcription is differentially regulated by oxidative stress in an Sp1-dependent manner |
Q36906799 | SUMO2/3 modification of cyclin E contributes to the control of replication origin firing |
Q35568644 | SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites. |
Q33870712 | SUMOylation and de-SUMOylation in response to DNA damage. |
Q30583585 | SUMOylation inhibits FOXM1 activity and delays mitotic transition. |
Q35031726 | SUMOylation is developmentally regulated and required for cell pairing during conjugation in Tetrahymena thermophila |
Q38979379 | SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner. |
Q35275798 | SUMOylation occurs in acute kidney injury and plays a cytoprotective role |
Q31171264 | SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway |
Q41417327 | SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy |
Q42920096 | SUMOylation of the ING1b tumor suppressor regulates gene transcription |
Q38509671 | Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair |
Q59313925 | Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells |
Q33985238 | Small ubiquitin-like modifier (SUMO) isoforms and conjugation-independent function in DNA double-strand break repair pathways |
Q36717273 | Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival |
Q34537060 | Small ubiquitin-like modifier modification of arrestin-3 regulates receptor trafficking |
Q42604248 | Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia |
Q35803573 | Small ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma |
Q38656328 | Spatiotemporal regulation of posttranslational modifications in the DNA damage response |
Q38219978 | Sumoylation and the DNA damage response |
Q35539883 | Sumoylation influences DNA break repair partly by increasing the solubility of a conserved end resection protein. |
Q36090318 | Sumoylation of MDC1 is important for proper DNA damage response |
Q33698685 | Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association |
Q36189334 | Sumoylation regulates EXO1 stability and processing of DNA damage |
Q38901752 | System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability. |
Q28115456 | Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair |
Q38959150 | Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity |
Q39251706 | Systematic identification of functional residues in mammalian histone H2AX |
Q24295574 | TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes |
Q50926267 | Targeting histone deacetylase 4/ubiquitin-conjugating enzyme 9 impairs DNA repair for radiosensitization of hepatocellular carcinoma cells in mice. |
Q37875478 | The BRCA1 ubiquitin ligase and homologous recombination repair |
Q27861055 | The DNA Damage Response: Making It Safe to Play with Knives |
Q37977004 | The DNA damage response and cancer therapy |
Q33870522 | The DNA damage response: the omics era and its impact |
Q24302499 | The E3 ligase RNF8 regulates KU80 removal and NHEJ repair |
Q94951027 | The HSV-1 ubiquitin ligase ICP0: modifying the cellular proteome to promote infection |
Q64103296 | The Impact of the C-Terminal Region on the Interaction of Topoisomerase II Alpha with Mitotic Chromatin |
Q34127693 | The MRN complex in double-strand break repair and telomere maintenance |
Q54582549 | The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. |
Q37397475 | The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair |
Q34801900 | The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage |
Q39194387 | The Role of PIAS SUMO E3-Ligases in Cancer |
Q47095192 | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. |
Q36419253 | The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation. |
Q35225049 | The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death |
Q24307375 | The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA |
Q92570284 | The SUMO Pathway in Hematomalignancies and Their Response to Therapies |
Q36619481 | The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci |
Q27865256 | The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition |
Q38126813 | The SUMO system: a master organizer of nuclear protein assemblies. |
Q39560571 | The USP1/UAF1 complex promotes double-strand break repair through homologous recombination |
Q36178244 | The Use of Laser Microirradiation to Investigate the Roles of Cohesins in DNA Repair |
Q33804824 | The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites |
Q64077175 | The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms |
Q39160987 | The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases |
Q38056099 | The emerging role of Polycomb repressors in the response to DNA damage |
Q38056496 | The heterochromatic barrier to DNA double strand break repair: how to get the entry visa |
Q33941037 | The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. |
Q36293421 | The mechanism of Jurkat cells apoptosis induced by Aggregatibacter actinomycetemcomitans cytolethal distending toxin |
Q33995521 | The multifunctional SNM1 gene family: not just nucleases |
Q34191583 | The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair |
Q52730181 | The post-translational modification, SUMOylation, and cancer (Review). |
Q37381571 | The predictive value of 53BP1 and BRCA1 mRNA expression in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy |
Q38738534 | The proteasome enters the meiotic prophase fray |
Q37888122 | The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks |
Q37807639 | The ubiquitous role of ubiquitin in the DNA damage response |
Q37987125 | The use of fluorescence microscopy to study the association between herpesviruses and intrinsic resistance factors |
Q41861552 | Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation |
Q29871439 | Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α. |
Q33602611 | USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism |
Q89768702 | Ubiquitin and ubiquitin-like molecules in DNA double strand break repair |
Q63965414 | Ubiquitin signalling in DNA replication and repair |
Q24293610 | Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination |
Q36670706 | Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling |
Q39031491 | Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks |
Q34041994 | Uncovering global SUMOylation signaling networks in a site-specific manner |
Q64387083 | WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks |
Q26742134 | Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair |
Q92832654 | hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy |
Q28246258 | mRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer |
Search more.