| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/IJC.28129 |
| P953 | full work available online at | https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fijc.28129 |
| https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.28129 | ||
| P698 | PubMed publication ID | 23436247 |
| P2093 | author name string | Sanjeev Das | |
| Abhishek Bhardwaj | |||
| Yatendra Kumar Satija | |||
| P2860 | cites work | Ex vivo expansion, adipogenesis and neurogenesis of cryopreserved human bone marrow mesenchymal stem cells | Q53574563 |
| Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins | Q80262122 | ||
| USP10: friend and foe | Q82845098 | ||
| Nuclear expression of S-phase kinase-associated protein 2 predicts poor prognosis of hepatocellular carcinoma | Q83929381 | ||
| Identification of a family of human F-box proteins | Q22010703 | ||
| Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53 | Q22253350 | ||
| Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase | Q24292829 | ||
| Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization | Q24292930 | ||
| Regulation of cell cycle progression and gene expression by H2A deubiquitination | Q24296401 | ||
| The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 | Q24296502 | ||
| USP10 regulates p53 localization and stability by deubiquitinating p53 | Q24296967 | ||
| The expression patterns of deubiquitinating enzymes, USP22 and Usp22 | Q24299924 | ||
| Role of histone H2A ubiquitination in Polycomb silencing | Q24305090 | ||
| ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor | Q24306428 | ||
| DNA-damage response control of E2F7 and E2F8 | Q24306816 | ||
| The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression | Q24307439 | ||
| USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A | Q24311562 | ||
| Defining the human deubiquitinating enzyme interaction landscape | Q24315885 | ||
| USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1 | Q24316142 | ||
| Suppression of cancer cell growth by promoting cyclin D1 degradation | Q24317660 | ||
| Molecular basis of Pirh2-mediated p53 ubiquitylation | Q24319435 | ||
| VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases | Q24322407 | ||
| Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 | Q24328775 | ||
| Pirh2 E3 Ubiquitin Ligase Monoubiquitinates DNA Polymerase Eta To Suppress Translesion DNA Synthesis | Q38630697 | ||
| PGC-1α, a Key Modulator of p53, Promotes Cell Survival upon Metabolic Stress | Q39440511 | ||
| USP22 Acts as an Oncogene by the Activation of BMI-1-Mediated INK4a/ARF Pathway and Akt Pathway | Q39472076 | ||
| Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6 | Q39576878 | ||
| SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis | Q39811582 | ||
| High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers | Q39850997 | ||
| The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network | Q39948774 | ||
| Skp2 suppresses p53-dependent apoptosis by inhibiting p300. | Q40017621 | ||
| Ubiquitin: Roles in protein modification and breakdown | Q40136591 | ||
| Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist | Q40202330 | ||
| The isopeptidase USP2a protects human prostate cancer from apoptosis | Q40236434 | ||
| Degradation of Tob1 mediated by SCFSkp2-dependent ubiquitination | Q40236469 | ||
| The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation | Q40418287 | ||
| The Roles of VHL-Dependent Ubiquitination in Signaling and Cancer | Q41911531 | ||
| Good COP1 or bad COP1? In vivo veritas | Q42133928 | ||
| CHIP-dependent p53 regulation occurs specifically during cellular senescence | Q42478861 | ||
| An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. | Q42797525 | ||
| Mutations of the VHL tumour suppressor gene in renal carcinoma | Q42806703 | ||
| Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition | Q42819481 | ||
| p53-induced RING-H2 protein, a novel marker for poor survival in hepatocellular carcinoma after hepatic resection | Q43580782 | ||
| The MDM2 RING-finger domain is required to promote p53 nuclear export | Q45301160 | ||
| The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase | Q46603785 | ||
| USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development | Q53171868 | ||
| M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP | Q24329203 | ||
| Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C | Q24336712 | ||
| MdmX is a substrate for the deubiquitinating enzyme USP2a | Q24336863 | ||
| Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin' | Q24336917 | ||
| Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis | Q24338676 | ||
| Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer | Q24528253 | ||
| Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer | Q24553135 | ||
| The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins | Q24564802 | ||
| Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks | Q24608599 | ||
| Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands | Q24631957 | ||
| Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer | Q24670460 | ||
| RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis | Q26853207 | ||
| Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade | Q27620360 | ||
| Structure of a BRCA1-BARD1 heterodimeric RING-RING complex | Q27635007 | ||
| Mechanisms underlying ubiquitination | Q27860656 | ||
| p53, the cellular gatekeeper for growth and division | Q27860990 | ||
| The genomic landscapes of human breast and colorectal cancers | Q27861078 | ||
| SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box | Q27936367 | ||
| A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p | Q27939049 | ||
| Surfing the p53 network | Q28032484 | ||
| Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
| SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 | Q28137860 | ||
| Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha | Q28143121 | ||
| beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation | Q28144504 | ||
| Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage | Q28182301 | ||
| Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase | Q28202311 | ||
| Role of direct interaction in BRCA1 inhibition of estrogen receptor activity | Q28204456 | ||
| Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase | Q28215069 | ||
| Induction of homologue of Slimb ubiquitin ligase receptor by mitogen signaling | Q28216569 | ||
| Cancer susceptibility and the functions of BRCA1 and BRCA2 | Q28217784 | ||
| Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells | Q28237026 | ||
| MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy | Q36047902 | ||
| SCF-mediated protein degradation and cell cycle control | Q36101758 | ||
| Genomic models of metastatic cancer: functional analysis of death-from-cancer signature genes reveals aneuploid, anoikis-resistant, metastasis-enabling phenotype with altered cell cycle control and activated Polycomb Group (PcG) protein chromatin si | Q36499888 | ||
| Drug discovery in the ubiquitin-proteasome system. | Q36525810 | ||
| The roles of synoviolin in crosstalk between endoplasmic reticulum stress-induced apoptosis and p53 pathway | Q36854547 | ||
| Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations | Q37011738 | ||
| JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation | Q37238734 | ||
| Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers | Q37272977 | ||
| Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activity | Q37283603 | ||
| BRCA1 and its toolbox for the maintenance of genome integrity | Q37507563 | ||
| Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8 | Q37827465 | ||
| A novel oncoprotein Pirh2: rising from the shadow of MDM2 | Q37834073 | ||
| The cullin protein family | Q37873586 | ||
| The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer | Q28253300 | ||
| A dynamic role of HAUSP in the p53-Mdm2 pathway | Q28253645 | ||
| DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 | Q28254119 | ||
| Elevated expression of Wnt antagonists is a common event in hepatoblastomas | Q28256831 | ||
| The ubiquitin ligase COP1 is a critical negative regulator of p53 | Q28258057 | ||
| ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage | Q28260019 | ||
| Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity | Q28270986 | ||
| The SCF ubiquitin ligase: insights into a molecular machine | Q28279993 | ||
| Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing | Q28287373 | ||
| COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas | Q28288506 | ||
| Over-expression of human UREB1 in colorectal cancer: HECT domain of human UREB1 inhibits the activity of tumor suppressor p53 protein | Q28295385 | ||
| Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase | Q28506124 | ||
| Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation | Q28609772 | ||
| Live or let die: the cell's response to p53 | Q29547663 | ||
| Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein | Q29615928 | ||
| Ubiquitin ligases: cell-cycle control and cancer | Q29617992 | ||
| Identification of the von Hippel-Lindau disease tumor suppressor gene | Q29618644 | ||
| Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal Cancer | Q30051055 | ||
| BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha | Q33576505 | ||
| Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation | Q33755125 | ||
| HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase | Q34139276 | ||
| Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. | Q34283106 | ||
| A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1). | Q34321355 | ||
| Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer. | Q34368432 | ||
| Substrate Phosphorylation and Feedback Regulation in JFK-promoted p53 Destabilization | Q34575899 | ||
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation | Q34835596 | ||
| BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP | Q34863348 | ||
| RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer | Q35036565 | ||
| Decision making by p53: life, death and cancer | Q35116663 | ||
| BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. | Q35618582 | ||
| Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase | Q35749504 | ||
| The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2). | Q35805056 | ||
| Skp2 is oncogenic and overexpressed in human cancers | Q35862209 | ||
| The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer | Q35911159 | ||
| Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation. | Q35917801 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2759-2768 | |
| P577 | publication date | 2013-03-25 | |
| P1433 | published in | International Journal of Cancer | Q332492 |
| P1476 | title | A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer | |
| P478 | volume | 133 |
| Q54974008 | A novel reporter for real-time, quantitative imaging of AKT-directed K63-poly-ubiquitination in living cells. |
| Q37727613 | Discovery of PI-1840, a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity |
| Q27930260 | Dynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity. |
| Q92127608 | Functional Toll-Like Receptors (TLRs) Are Expressed by a Majority of Primary Human Acute Myeloid Leukemia Cells and Inducibility of the TLR Signaling Pathway Is Associated with a More Favorable Phenotype |
| Q34448273 | Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system |
| Q33627342 | Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation. |
| Q35273519 | SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice |
| Q47128996 | Significance of the E3 ubiquitin protein UBR5 as an oncogene and a prognostic biomarker in colorectal cancer. |
| Q34877823 | Silencing SlELP2L, a tomato Elongator complex protein 2-like gene, inhibits leaf growth, accelerates leaf, sepal senescence, and produces dark-green fruit |
| Q47564348 | Support vector machine classifier for prediction of the metastasis of colorectal cancer |
| Q92619188 | The functional role of RNF113A in cervical carcinogenesis |
| Q26782159 | The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma |
| Q38846078 | UBE2S is associated with malignant characteristics of breast cancer cells |
| Q33779187 | UBE2T knockdown inhibits gastric cancer progression |
| Q33648632 | USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt. |
| Q35003999 | WWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in mice |
| Q36997572 | p53 regulation upon genotoxic stress: intricacies and complexities |
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