scholarly article | Q13442814 |
P2093 | author name string | A. Ougolkov | |
B. Zhang | |||
K. Yamashita | |||
M. Mai | |||
S. Y. Fuchs | |||
T. Minamoto | |||
V. Bilim | |||
P2860 | cites work | Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 |
ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase | Q24290903 | ||
Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U | Q24672630 | ||
The ubiquitin system | Q27860803 | ||
betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932. | Q28118570 | ||
p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27 | Q28137813 | ||
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 | Q28137860 | ||
The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis | Q28138414 | ||
beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation | Q28144504 | ||
Five human genes encoding F-box proteins: chromosome mapping and analysis in human tumors | Q28145273 | ||
The Hedgehog and Wnt signalling pathways in cancer | Q28189485 | ||
Beta-catenin--a linchpin in colorectal carcinogenesis? | Q28198211 | ||
Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100 | Q28216699 | ||
Apoptosis in the pathogenesis and treatment of disease | Q28235731 | ||
Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene | Q28506095 | ||
beta-catenin is a target for the ubiquitin-proteasome pathway | Q29547589 | ||
Activators and target genes of Rel/NF-kappaB transcription factors | Q29547882 | ||
NF-kappaB in cancer: from innocent bystander to major culprit | Q29614603 | ||
NF-kappaB at the crossroads of life and death | Q29619302 | ||
The oncogenic activation of beta-catenin | Q33540073 | ||
Ubiquitin-mediated proteolysis: biological regulation via destruction | Q33910576 | ||
NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases | Q33930920 | ||
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment | Q33943198 | ||
Detection of oncogenes in the diagnosis of cancers with active oncogenic signaling | Q34162584 | ||
Blocking oncogenic Ras signaling for cancer therapy | Q34311585 | ||
MDM2: life without p53. | Q34326204 | ||
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer | Q34415244 | ||
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. | Q34415250 | ||
Ubiquitin-mediated degradation of cellular proteins in health and disease | Q34490180 | ||
p53-Mdm2--the affair that never ends | Q34605732 | ||
Emerging concepts in colorectal neoplasia | Q34800070 | ||
Tumor formation by genetic mutations in the components of the Wnt signaling pathway | Q35161748 | ||
The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer | Q35691542 | ||
IkappaB kinase: beginning, not the end | Q36039922 | ||
Inhibition of HOS expression and activities by Wnt pathway | Q40750211 | ||
Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB. | Q40803270 | ||
p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells | Q40918524 | ||
The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. | Q40967633 | ||
Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase | Q42631679 | ||
Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. | Q48354837 | ||
Basic Medical Research Award. The ubiquitin system | Q48372080 | ||
Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP. | Q50335887 | ||
Emi1 proteolysis: how SCF(beta-Trcp1) helps to activate the anaphase-promoting complex. | Q52103792 | ||
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. | Q52826936 | ||
Strongly reduced expression of the cell cycle inhibitor p27 in endometrial neoplasia. | Q53421954 | ||
Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC. | Q54541774 | ||
APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers | Q57693627 | ||
P433 | issue | 15 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | colorectal cancer | Q188874 |
colorectal carcinoma | Q25493920 | ||
P304 | page(s) | 1161-1170 | |
P577 | publication date | 2004-08-03 | |
P1433 | published in | Journal of the National Cancer Institute | Q400279 |
P1476 | title | Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal Cancer | |
P478 | volume | 96 |
Q41712580 | A new layer of degradation mechanism for PR-Set7/Set8 during cell cycle |
Q38084210 | A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer |
Q58164878 | A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth |
Q37217655 | Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiation |
Q40266758 | CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling |
Q48216286 | Centromere protein W interacts with beta-transducin repeat-containing protein 1 and modulates its subcellular localization. |
Q34127839 | Circadian gene variants in cancer. |
Q24294824 | Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cells |
Q37096504 | Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer |
Q37891671 | Cross-Regulation Between Wnt and NF-κB Signaling Pathways |
Q52715797 | Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis. |
Q28074708 | Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation |
Q53690290 | DNA Damage Inducible Transcript 4 Gene: The Switch of the Metabolism as Potential Target in Cancer. |
Q24648025 | Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer |
Q30278581 | Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis |
Q89791100 | Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins |
Q40017813 | Differential effect of NF-kappaB activity on beta-catenin/Tcf pathway in various cancer cells |
Q28086796 | Dysregulation of ubiquitin ligases in cancer |
Q35082710 | E3 ubiquitin ligases as cancer targets and biomarkers |
Q47636038 | E3 ubiquitin ligases in cancer and implications for therapies |
Q34441649 | Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1 |
Q38785208 | Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. |
Q53060819 | Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells. |
Q35758175 | Expression of β-transducin repeat-containing E3 ubiquitin protein ligase in human glioma and its correlation with prognosis |
Q61810405 | FBXO22 Suppresses Metastasis in Human Renal Cell Carcinoma via Inhibiting MMP-9-Mediated Migration and Invasion and VEGF-Mediated Angiogenesis |
Q51533176 | FBXO25 promotes cell proliferation, invasion, and migration of NSCLC. |
Q92856149 | FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway |
Q33689786 | Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine |
Q52349771 | Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways. |
Q50026061 | Functional significance and therapeutic implication of ring-type E3 ligases in colorectal cancer |
Q37330990 | Garcinol regulates EMT and Wnt signaling pathways in vitro and in vivo, leading to anticancer activity against breast cancer cells |
Q39450022 | Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine |
Q38823288 | Hint1 Up-Regulates IκBα by Targeting the β-TrCP Subunit of SCF E3 Ligase in Human Hepatocellular Carcinoma Cells. |
Q34635123 | Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming |
Q50974518 | Mathematical modelling suggests a differential impact of β-transducin repeat-containing protein paralogues on Wnt/β-catenin signalling dynamics. |
Q37320122 | MicroRNA binding site polymorphisms as biomarkers of cancer risk |
Q38577492 | MicroRNA regulation of F-box proteins and its role in cancer. |
Q35011051 | Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt. |
Q28512155 | Myeloid leukemia factor 1 associates with a novel heterogeneous nuclear ribonucleoprotein U-like molecule |
Q37995696 | NF-κB and the link between inflammation and cancer |
Q39766076 | Nuclear factor-kappa B inhibition reduces markedly cell proliferation in Epstein-Barr virus-infected stomach cancer, but affects variably in Epstein-Barr virus-negative stomach cancer |
Q35757254 | Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. |
Q28209990 | Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2 |
Q39235953 | Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett's epithelium |
Q28390295 | REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase |
Q38828721 | Recent advances in SCF ubiquitin ligase complex: Clinical implications |
Q48375223 | Reciprocal regulation between βTrCP and Smurf1 suppresses proliferative capacity of liver cancer cells. |
Q39921991 | Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2. |
Q33988164 | Retracted: Silymarin Targets β-Catenin Signaling in Blocking Migration/Invasion of Human Melanoma Cells |
Q35012352 | Roles of F-box proteins in cancer |
Q21090517 | Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism |
Q54982486 | S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer. |
Q35613215 | SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection |
Q36119281 | SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. |
Q53118754 | SGT1 regulates Akt signaling by promoting beta-TrCP-dependent PHLPP1 degradation in gastric cancer cells. |
Q38435553 | Seten: a tool for systematic identification and comparison of processes, phenotypes, and diseases associated with RNA-binding proteins from condition-specific CLIP-seq profiles. |
Q47128996 | Significance of the E3 ubiquitin protein UBR5 as an oncogene and a prognostic biomarker in colorectal cancer. |
Q64259739 | Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location |
Q91928988 | Targeting the Canonical WNT/β-Catenin Pathway in Cancer Treatment Using Non-Steroidal Anti-Inflammatory Drugs |
Q26866185 | Targeting the ubiquitin pathway for cancer treatment |
Q33419571 | The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity |
Q36029051 | The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis |
Q92446155 | The Role of Ubiquitination in Regulating Embryonic Stem Cell Maintenance and Cancer Development |
Q24324551 | The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation |
Q38087182 | The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer |
Q37591349 | The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor |
Q36420150 | Therapeutic intervention of proanthocyanidins on the migration capacity of melanoma cells is mediated through PGE2 receptors and β-catenin signaling molecules |
Q29617992 | Ubiquitin ligases: cell-cycle control and cancer |
Q33233938 | Ubiquitous mitochondrial creatine kinase downregulated in oral squamous cell carcinoma |
Q33839776 | Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin |
Q39779371 | Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA. |
Q33530099 | beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor |
Q89611790 | lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer |
Q98384399 | β-TrCP suppresses the migration and invasion of trophoblast cells in preeclampsia by down-regulating Snail |
Q49357675 | β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer |
Search more.