| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S10555-017-9703-Z |
| P698 | PubMed publication ID | 29043469 |
| P2093 | author name string | Jia Liu | |
| Bin Wang | |||
| Wenyi Wei | |||
| Dong Wang | |||
| Leina Ma | |||
| P2860 | cites work | Mdm2 induces mono-ubiquitination of FOXO4 | Q21092186 |
| Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP | Q21666110 | ||
| Identification of the receptor component of the IkappaBalpha-ubiquitin ligase | Q22008569 | ||
| NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN | Q24292919 | ||
| HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes | Q24292928 | ||
| A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer | Q24294937 | ||
| PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility | Q24296955 | ||
| PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 | Q24297155 | ||
| Alterations of anaphase-promoting complex genes in human colon cancer cells | Q24297514 | ||
| Novel RING E3 ubiquitin ligases in breast cancer | Q24300517 | ||
| UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids | Q24300880 | ||
| Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy | Q24300975 | ||
| Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage | Q24303577 | ||
| Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase | Q24304122 | ||
| Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression | Q24314416 | ||
| Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration | Q24316451 | ||
| Molecular basis of Pirh2-mediated p53 ubiquitylation | Q24319435 | ||
| Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT | Q24338165 | ||
| Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit | Q24534998 | ||
| Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells | Q24615775 | ||
| E3 ligase Nedd4 promotes axon branching by downregulating PTEN | Q24630190 | ||
| Nedd4 controls animal growth by regulating IGF-1 signaling | Q24632761 | ||
| MDM2 regulates dihydrofolate reductase activity through monoubiquitination | Q24634031 | ||
| Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways | Q24647626 | ||
| Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions | Q24651528 | ||
| Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series | Q24655287 | ||
| Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination | Q24656742 | ||
| Rabring7, a novel Rab7 target protein with a RING finger motif | Q24669620 | ||
| Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer | Q24670460 | ||
| Insights into APC/C: from cellular function to diseases and therapeutics | Q26740196 | ||
| Mitochondrial dysfunction in Parkinson's disease | Q26741872 | ||
| The role of ubiquitylation in immune defence and pathogen evasion | Q26860775 | ||
| Investigating metformin for cancer prevention and treatment: the end of the beginning | Q26863783 | ||
| Targeting the ubiquitin pathway for cancer treatment | Q26866185 | ||
| Atomic structure of the APC/C and its mechanism of protein ubiquitination | Q27316585 | ||
| In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
| An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase | Q27662837 | ||
| Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development | Q27685122 | ||
| The genomic landscapes of human breast and colorectal cancers | Q27861078 | ||
| SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box | Q27936367 | ||
| Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemness | Q28077156 | ||
| p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27 | Q28137813 | ||
| Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1 | Q28138898 | ||
| Mdm2 binds p73 alpha without targeting degradation | Q28141357 | ||
| Identification of a set of genes with developmentally down-regulated expression in the mouse brain | Q28187594 | ||
| Signal transduction by the TGF-beta superfamily | Q28201963 | ||
| Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase | Q28202311 | ||
| Themes and variations on ubiquitylation | Q28206411 | ||
| Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication | Q28209282 | ||
| Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase | Q28215069 | ||
| Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells | Q28237026 | ||
| The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling | Q28240232 | ||
| Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells | Q28249125 | ||
| Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase | Q28249846 | ||
| Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer | Q28266601 | ||
| S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth | Q28269583 | ||
| Effects of partner proteins on BCA2 RING ligase activity | Q34153494 | ||
| MDM2, MDMX and p53 in oncogenesis and cancer therapy | Q34166049 | ||
| Interaction between HERC1 and M2-type pyruvate kinase | Q34185334 | ||
| Androgens differentially regulate the expression of NEDD4L transcripts in LNCaP human prostate cancer cells | Q34276421 | ||
| Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension | Q34324276 | ||
| The central region of HDM2 provides a second binding site for p53. | Q34335012 | ||
| Mammalian HECT ubiquitin-protein ligases: biological and pathophysiological aspects | Q34336329 | ||
| Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer. | Q34368432 | ||
| Role of the BCA2 ubiquitin E3 ligase in hormone responsive breast cancer | Q34416164 | ||
| NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling | Q34420227 | ||
| The HERC proteins: functional and evolutionary insights. | Q34427955 | ||
| Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1 | Q34441649 | ||
| Molecular characterization of ring finger protein 11. | Q34445795 | ||
| The human papillomavirus E6 protein and its contribution to malignant progression | Q34468780 | ||
| Functional and pathological relevance of HERC family proteins: a decade later. | Q34510463 | ||
| Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p | Q34516234 | ||
| The logic of TGFbeta signaling. | Q34522372 | ||
| HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability | Q34579811 | ||
| Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins | Q34610662 | ||
| Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3. | Q34717463 | ||
| Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant: implications for essential hypertension | Q34749197 | ||
| NF-kappaB as a therapeutic target in cancer | Q34750172 | ||
| Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice. | Q34761024 | ||
| The ubiquitin E3 ligase ITCH enhances breast tumor progression by inhibiting the Hippo tumor suppressor pathway | Q34786592 | ||
| Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells. | Q34786933 | ||
| SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction | Q34788849 | ||
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation | Q34835596 | ||
| P53 mRNA controls p53 activity by managing Mdm2 functions | Q34927261 | ||
| Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP. | Q35011473 | ||
| Roles of F-box proteins in cancer | Q35012352 | ||
| Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling | Q35013177 | ||
| Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27 | Q35022507 | ||
| Inhibiting the p53-MDM2 interaction: an important target for cancer therapy | Q35058579 | ||
| NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling | Q35060566 | ||
| Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis | Q39677519 | ||
| Interplay between Cdh1 and JNK activity during the cell cycle | Q39687769 | ||
| Axin determines cell fate by controlling the p53 activation threshold after DNA damage | Q39803554 | ||
| Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells | Q39822190 | ||
| High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers | Q39850997 | ||
| FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression | Q39904718 | ||
| The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11. | Q39947573 | ||
| Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types | Q40050651 | ||
| p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells. | Q40067416 | ||
| Ubiquitin: Roles in protein modification and breakdown | Q40136591 | ||
| The amplified WWP1 gene is a potential molecular target in breast cancer | Q40165059 | ||
| HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism | Q40371290 | ||
| Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells | Q40410781 | ||
| Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation | Q40485180 | ||
| Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm | Q40637846 | ||
| PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy | Q40765673 | ||
| Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms | Q40773986 | ||
| Bimodal degradation of MLL by SCFSkp2 and APCCdc20 assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions | Q41436188 | ||
| Skp2 knockout reduces cell proliferation and mouse body size: and prevents cancer? | Q41579194 | ||
| MicroRNA-25 promotes gastric cancer proliferation, invasion, and migration by directly targeting F-box and WD-40 Domain Protein 7, FBXW7. | Q41759540 | ||
| The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases | Q41817040 | ||
| p53 Ubiquitination and proteasomal degradation | Q42010907 | ||
| Good COP1 or bad COP1? In vivo veritas | Q42133928 | ||
| Inactivation of the p53 pathway in retinoblastoma. | Q42152329 | ||
| Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture | Q42277730 | ||
| Regulation of Commissureless by the ubiquitin ligase DNedd4 is required for neuromuscular synaptogenesis in Drosophila melanogaster | Q42721859 | ||
| Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase | Q42779085 | ||
| Parkin as a tumor suppressor gene for hepatocellular carcinoma | Q42811415 | ||
| Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis. | Q43508536 | ||
| p53-induced RING-H2 protein, a novel marker for poor survival in hepatocellular carcinoma after hepatic resection | Q43580782 | ||
| Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas | Q43861270 | ||
| Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation | Q44605497 | ||
| Overexpression of human beta TrCP1 deleted of its F box induces tumorigenesis in transgenic mice | Q45286163 | ||
| The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance | Q45341789 | ||
| Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch | Q46802020 | ||
| Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1. | Q46953383 | ||
| HERC1 mutations in idiopathic intellectual disability | Q50345824 | ||
| Look Out Autophagy, Ubiquilin UPS Its Game. | Q50492791 | ||
| Reciprocal Regulation between 53BP1 and the Anaphase-Promoting Complex/Cyclosome Is Required for Genomic Stability during Mitotic Stress. | Q51127063 | ||
| Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer. | Q51201474 | ||
| MDM2 and MDMX in cancer and development. | Q51889545 | ||
| WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinoma. | Q53013401 | ||
| BCA2 is differentially expressed in renal oncocytoma: an analysis of 158 renal neoplasms. | Q53129198 | ||
| Overexpression of CDC20 predicts poor prognosis in primary non-small cell lung cancer patients. | Q53175100 | ||
| Reduction of transforming growth factor-beta type II receptor is caused by the enhanced ubiquitin-dependent degradation in human renal cell carcinoma. | Q53302797 | ||
| Correlation between Skp2 expression and nodal metastasis in stage I and II oral squamous cell carcinomas. | Q53310406 | ||
| HERC2 is an E3 ligase that targets BRCA1 for degradation. | Q53312505 | ||
| Dissection of the APCCdh1-Skp2 cascade in breast cancer. | Q53487699 | ||
| The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells. | Q53534176 | ||
| APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers | Q57693627 | ||
| DNA damage: ubiquitin marks the spot | Q58236930 | ||
| A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase | Q58376453 | ||
| The SCF ubiquitin ligase: insights into a molecular machine | Q28279993 | ||
| Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome | Q28283932 | ||
| Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis | Q28287406 | ||
| COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas | Q28288506 | ||
| E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the ubiquitination pathway by a novel motif, the L2G box | Q28291338 | ||
| Ube3a/E6AP is involved in a subset of MeCP2 functions | Q28293254 | ||
| Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells | Q28297767 | ||
| betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis | Q28306984 | ||
| Dual mode of degradation of Cdc25 A phosphatase | Q28386155 | ||
| NAHA, a novel hydroxamic acid-derivative, inhibits growth and angiogenesis of breast cancer in vitro and in vivo | Q28481887 | ||
| Parkin-deficient mice are not a robust model of parkinsonism | Q28504677 | ||
| Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene | Q28506095 | ||
| Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication | Q28507216 | ||
| Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis | Q28508088 | ||
| The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1 | Q28509515 | ||
| ERK and the F-box protein betaTRCP target STAT1 for degradation | Q28590914 | ||
| Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation | Q28609772 | ||
| The anaphase-promoting complex: proteolysis in mitosis and beyond | Q28610045 | ||
| The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation | Q29615268 | ||
| Ubiquitin: structures, functions, mechanisms | Q29616462 | ||
| Physiological functions of the HECT family of ubiquitin ligases | Q29617293 | ||
| Nonproteolytic functions of ubiquitin in cell signaling | Q29617294 | ||
| Recycling the Cell Cycle | Q29999767 | ||
| Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal Cancer | Q30051055 | ||
| Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. | Q30596621 | ||
| Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. | Q31041084 | ||
| Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. | Q33209208 | ||
| Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study | Q33403930 | ||
| BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction | Q33519521 | ||
| Identification and characterization of the first small molecule inhibitor of MDMX | Q33524716 | ||
| Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions | Q33632965 | ||
| Human ITCH E3 ubiquitin ligase deficiency causes syndromic multisystem autoimmune disease. | Q33708589 | ||
| Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein | Q33782514 | ||
| mdm2: a bridge over the two tumour suppressors, p53 and Rb. | Q33807825 | ||
| Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism | Q33838261 | ||
| The elusive role of the SPRY2 domain in RyR1. | Q35079050 | ||
| Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability | Q35123240 | ||
| Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect | Q35239585 | ||
| The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation | Q35371834 | ||
| MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C. | Q35453377 | ||
| Mutational spectrum of adult T-ALL | Q35550090 | ||
| The MDM2 RING domain and central acidic domain play distinct roles in MDM2 protein homodimerization and MDM2-MDMX protein heterodimerization | Q35608179 | ||
| SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection | Q35613215 | ||
| A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20. | Q35742838 | ||
| Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit | Q35787361 | ||
| Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization | Q35857019 | ||
| Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors | Q35871417 | ||
| Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation. | Q35917801 | ||
| Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer. | Q36017990 | ||
| Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. | Q36119759 | ||
| DDB2 modulates TGF-β signal transduction in human ovarian cancer cells by downregulating NEDD4L. | Q36299135 | ||
| Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins | Q36310068 | ||
| Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells | Q36322375 | ||
| Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy | Q36591350 | ||
| Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins | Q36703456 | ||
| Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis | Q36734913 | ||
| Ubiquitin proteasome system (UPS): what can chromatin do for you? | Q36741709 | ||
| Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins | Q36889339 | ||
| The genetic landscape of high-risk neuroblastoma | Q36929803 | ||
| CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer | Q36952921 | ||
| Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2. | Q36986557 | ||
| Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein | Q37073031 | ||
| Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness | Q37091520 | ||
| Targeting ubiquitination for cancer therapies. | Q37158445 | ||
| Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation | Q37162851 | ||
| The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications. | Q37163747 | ||
| The HECT family of E3 ubiquitin ligases: multiple players in cancer development | Q37206488 | ||
| Derailed endocytosis: an emerging feature of cancer | Q37307506 | ||
| Regulation of metformin response by breast cancer associated gene 2. | Q37448089 | ||
| FBXW7 mutations in melanoma and a new therapeutic paradigm | Q33845217 | ||
| Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2. | Q33888656 | ||
| FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma. | Q33889158 | ||
| Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2. | Q34003810 | ||
| Role of Pirh2 in mediating the regulation of p53 and c-Myc | Q34085616 | ||
| PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice. | Q34093865 | ||
| The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation. | Q34138871 | ||
| Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress | Q37680723 | ||
| Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets | Q37820063 | ||
| WWP1: a versatile ubiquitin E3 ligase in signaling and diseases | Q37952498 | ||
| Spotlight on the role of COP1 in tumorigenesis | Q38016673 | ||
| The ubiquitin proteasome system and efficacy of proteasome inhibitors in diseases | Q38019623 | ||
| Cullin-RING Ligases as attractive anti-cancer targets | Q38059746 | ||
| Smurf E3 ubiquitin ligases at the cross roads of oncogenesis and tumor suppression | Q38060912 | ||
| RBR E3-ligases at work | Q38182404 | ||
| WWP2: a multifunctional ubiquitin ligase gene | Q38248747 | ||
| NEDD4-2 (NEDD4L): the ubiquitin ligase for multiple membrane proteins | Q38272580 | ||
| The E3 ligase Itch in immune regulation and beyond. | Q38530613 | ||
| Involvement of F-BOX proteins in progression and development of human malignancies | Q38593624 | ||
| Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis | Q38630697 | ||
| RING-, HECT-, and RBR-type E3 Ubiquitin Ligases: Involvement in Human Cancer | Q38631141 | ||
| miR-367 promotes the proliferation and invasion of non-small cell lung cancer via targeting FBXW7. | Q38725021 | ||
| Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP. | Q38745588 | ||
| Elevated expression of WWP2 in human lung adenocarcinoma and its effect on migration and invasion | Q38755429 | ||
| miR-93 promotes TGF-β-induced epithelial-to-mesenchymal transition through downregulation of NEDD4L in lung cancer cells | Q38818616 | ||
| The role of ubiquitin-proteasome pathway in spermatogenesis | Q38819763 | ||
| Recent advances in SCF ubiquitin ligase complex: Clinical implications | Q38828721 | ||
| Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20. | Q38910500 | ||
| FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. | Q38928235 | ||
| Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies | Q39009613 | ||
| Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma | Q39031391 | ||
| MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression | Q39080347 | ||
| NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway | Q39279494 | ||
| Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. | Q39348126 | ||
| p28(GANK) prevents degradation of Oct4 and promotes expansion of tumor-initiating cells in hepatocarcinogenesis | Q39386300 | ||
| The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage | Q39408853 | ||
| Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA. | Q39451627 | ||
| Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity | Q39611297 | ||
| A Small-Molecule Inhibitor of MDMX Activates p53 and Induces Apoptosis | Q39632042 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 683-702 | |
| P577 | publication date | 2017-10-17 | |
| P1433 | published in | Cancer and Metastasis Reviews | Q2647982 |
| P1476 | title | E3 ubiquitin ligases in cancer and implications for therapies | |
| P478 | volume | 36 |
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