| scholarly article | Q13442814 |
| P50 | author | Marcos Malumbres | Q37619339 |
| Manuel Eguren | Q38640339 | ||
| Guillermo de Cárcer | Q42779115 | ||
| P2093 | author name string | Hiroyuki Yamano | |
| Marta Cañamero | |||
| Eusebio Manchado | |||
| Michelle Trickey | |||
| Sergio Moreno | |||
| María Guillamot | |||
| Irene García-Higuera | |||
| P433 | issue | 6 | |
| P304 | page(s) | 641-654 | |
| P577 | publication date | 2010-12-01 | |
| P1433 | published in | Cancer Cell | Q280018 |
| P1476 | title | Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase | |
| P478 | volume | 18 |
| Q35782988 | A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells |
| Q40973084 | A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit. |
| Q27727741 | A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct |
| Q89982718 | AKT regulates mitotic progression of mammalian cells by phosphorylating MASTL leading to PP2A inactivation |
| Q38839407 | AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest |
| Q33842900 | APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction |
| Q42322723 | APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability |
| Q44172547 | APC/C is an essential regulator of centrosome clustering |
| Q90279283 | APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis |
| Q33759013 | APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity |
| Q37122885 | Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme |
| Q30651536 | Analysis by live imaging of effects of the adenovirus E4orf4 protein on passage through mitosis of H1299 tumor cells |
| Q96122083 | Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification |
| Q36823669 | Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). |
| Q58796058 | Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1 |
| Q38845732 | Bistability of mitotic entry and exit switches during open mitosis in mammalian cells. |
| Q42831422 | BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy |
| Q64295741 | CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization |
| Q35619679 | Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription |
| Q39449351 | Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds? |
| Q41084291 | Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex |
| Q33584460 | Cdc20: a potential novel therapeutic target for cancer treatment |
| Q48522613 | Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B. |
| Q38935027 | Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic |
| Q38901065 | Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins. |
| Q88661083 | Clinically Applicable Inhibitors Impacting Genome Stability |
| Q34473920 | Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest |
| Q26777412 | Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis |
| Q48529643 | Cubism and the cell cycle: the many faces of the APC/C. |
| Q90291390 | Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis |
| Q52873703 | Cyclin-dependent kinase 1-dependent activation of APC/C ubiquitin ligase. |
| Q64106517 | Cycling for renewal: Cell cycle machinery maintains prostate cancer stem-like cells |
| Q36796457 | Deciphering the New Role of the Greatwall/PP2A Pathway in Cell Cycle Control |
| Q39027998 | Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL. |
| Q37671503 | Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible |
| Q47588118 | Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis. |
| Q99548829 | Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells |
| Q47636038 | E3 ubiquitin ligases in cancer and implications for therapies |
| Q38667730 | Express yourself: how PP2A-B55(Pab1) helps TORC1 talk to TORC2. |
| Q26998944 | Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis |
| Q27311643 | Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs |
| Q30554446 | Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals |
| Q41971182 | Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma |
| Q34365755 | Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair |
| Q26740196 | Insights into APC/C: from cellular function to diseases and therapeutics |
| Q92421651 | Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis |
| Q35754713 | Killing cells by targeting mitosis |
| Q30581433 | Kinetic framework of spindle assembly checkpoint signalling |
| Q30522305 | LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression |
| Q34009646 | Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance |
| Q58805925 | MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling |
| Q35453377 | MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C. |
| Q49284340 | Mastl overexpression is associated with epithelial to mesenchymal transition and predicts a poor clinical outcome in gastric cancer |
| Q30572037 | Microtubule-dependent regulation of mitotic protein degradation. |
| Q37845641 | Mitosis as an anti-cancer target |
| Q38053055 | Mitosis-targeted anti-cancer therapies: where they stand. |
| Q89583700 | Mitotic slippage is determined by p31comet and the weakening of the spindle-assembly checkpoint |
| Q26991427 | PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activation |
| Q36796453 | PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in Cancer |
| Q92444179 | PP2A Functions during Mitosis and Cytokinesis in Yeasts |
| Q38116193 | PP2A function toward mitotic kinases and substrates during the cell cycle |
| Q37990285 | PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates |
| Q30544640 | PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7. |
| Q57476147 | PP2A-B55 promotes nuclear envelope reformation after mitosis in |
| Q35082227 | PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit |
| Q90171686 | Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20 |
| Q34141156 | Phosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exit |
| Q37900486 | Phosphatases: providing safe passage through mitotic exit |
| Q54348226 | Preparing a cell for nuclear envelope breakdown: Spatio-temporal control of phosphorylation during mitotic entry. |
| Q51363519 | Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. |
| Q33686351 | Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression |
| Q35836388 | Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma. |
| Q24604987 | Protein kinases and phosphatases in the control of cell fate |
| Q28607574 | Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit |
| Q40485285 | Protein phosphatase 2A regulatory subunits are starting to reveal their functions in plant metabolism and development |
| Q35880406 | Protein phosphatases and their regulation in the control of mitosis |
| Q93183779 | Protein phosphatases in the regulation of mitosis |
| Q97421851 | RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit |
| Q39038812 | Regulation of Cell Division |
| Q94495298 | Requirement of PP2A-B56Par1 for the Stabilization of the CDK Inhibitor Rum1 and Activation of APC/CSte9 during Pre-Start G1 in S. pombe |
| Q41927888 | Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death. |
| Q89811259 | Squamous differentiation requires G2/mitosis slippage to avoid apoptosis |
| Q37956285 | Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis. |
| Q30596621 | Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. |
| Q46288094 | Taming the Beast: Control of APC/C(Cdc20)-Dependent Destruction. |
| Q35688708 | Targeting Cdc20 as a novel cancer therapeutic strategy |
| Q46488983 | Targeting mitotic exit for cancer treatment |
| Q38671036 | Targeting mitotic pathways for endocrine-related cancer therapeutics |
| Q26778544 | Targeting the Mitotic Catastrophe Signaling Pathway in Cancer |
| Q27306923 | The 3' untranslated region of the cyclin B mRNA is not sufficient to enhance the synthesis of cyclin B during a mitotic block in human cells |
| Q35971862 | The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis |
| Q48827871 | The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors |
| Q92651169 | The Anaphase Promoting Complex/Cyclosome (APC/C): A Versatile E3 Ubiquitin Ligase |
| Q41885460 | The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separation |
| Q28088697 | The Basic Biology of PP2A in Hematologic Cells and Malignancies |
| Q37999289 | The Greatwall kinase: a new pathway in the control of the cell cycle |
| Q35164326 | The biochemistry of mitosis |
| Q94474488 | The diverse roles of SPOP in prostate cancer and kidney cancer |
| Q41720317 | The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing |
| Q26861278 | The overlooked greatwall: a new perspective on mitotic control |
| Q34775279 | The tumor suppressor CDKN3 controls mitosis |
| Q47327040 | Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer. |
| Q91723836 | Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets |
| Q46609299 | Ubiquitin ligases in oncogenic transformation and cancer therapy |
| Q101140335 | Ubiquitin signaling in cell cycle control and tumorigenesis |
| Q38678006 | Ubiquitin, the centrosome, and chromosome segregation |
| Q90591255 | piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis |
| Q33728954 | α-endosulfine (ENSA) regulates exit from prophase I arrest in mouse oocytes |
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