| scholarly article | Q13442814 |
| P50 | author | Rob M F Wolthuis | Q83579358 |
| P2093 | author name string | Erik Voets | |
| P2860 | cites work | Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells | Q24295682 |
| PP2A delays APC/C-dependent degradation of separase-associated but not free securin | Q24296407 | ||
| MASTL is the human ortholog of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis | Q24298633 | ||
| Processing, localization, and requirement of human separase for normal anaphase progression | Q24299175 | ||
| Mitotic regulation of the human anaphase-promoting complex by phosphorylation | Q24301075 | ||
| Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line | Q24305823 | ||
| Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis | Q24306556 | ||
| Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery | Q24311665 | ||
| The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A | Q24317087 | ||
| Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance | Q24318937 | ||
| Mutations in Drosophila Greatwall/Scant reveal its roles in mitosis and meiosis and interdependence with Polo kinase | Q27314704 | ||
| Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest | Q27328547 | ||
| PP2A-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryos | Q27337616 | ||
| Suppression of scant identifies Endos as a substrate of greatwall kinase and a negative regulator of protein phosphatase 2A in mitosis | Q27338670 | ||
| The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis. | Q27936288 | ||
| A genome-wide screen identifies genes required for centromeric cohesion | Q27937102 | ||
| An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast | Q27938525 | ||
| Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway | Q27938753 | ||
| Budding yeast greatwall and endosulfines control activity and spatial regulation of PP2A(Cdc55) for timely mitotic progression. | Q27939884 | ||
| Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry | Q28115829 | ||
| APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box | Q28366341 | ||
| The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit | Q28749570 | ||
| Yeast endosulfines control entry into quiescence and chronological life span by inhibiting protein phosphatase 2A | Q28941167 | ||
| The APC/C inhibitor, Emi1, is essential for prevention of rereplication | Q30442630 | ||
| Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1 | Q30477585 | ||
| Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C | Q30480589 | ||
| Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring. | Q30491807 | ||
| Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited | Q30499682 | ||
| Cohesion fatigue induces chromatid separation in cells delayed at metaphase | Q30501417 | ||
| Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit | Q30502423 | ||
| Bypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans | Q30524103 | ||
| Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression | Q30541695 | ||
| Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals | Q30554446 | ||
| The spindle assembly checkpoint works like a rheostat rather than a toggle switch | Q30557537 | ||
| Separase sensor reveals dual roles for separase coordinating cohesin cleavage and cdk1 inhibition. | Q50493353 | ||
| Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction. | Q50646743 | ||
| Genome-wide survey of protein kinases required for cell cycle progression. | Q52654188 | ||
| Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin | Q57270125 | ||
| Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. | Q30596621 | ||
| Molecular architecture and mechanism of the anaphase-promoting complex | Q30653286 | ||
| Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis | Q34155315 | ||
| Securin and B-cyclin/CDK are the only essential targets of the APC. | Q34278659 | ||
| Mutual inhibition of separase and Cdk1 by two-step complex formation | Q34430229 | ||
| Cdc20: a WD40 activator for a cell cycle degradation machine | Q34646331 | ||
| Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila | Q36321813 | ||
| Mitosis: a matter of getting rid of the right protein at the right time | Q36335628 | ||
| Roles of Greatwall kinase in the regulation of cdc25 phosphatase | Q36536602 | ||
| Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation | Q37216805 | ||
| Reorganization of the nuclear envelope during open mitosis | Q37269387 | ||
| The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites | Q37420470 | ||
| Clearing the way for mitosis: is cohesin a target? | Q37506101 | ||
| Identification of substrates for cyclin dependent kinases | Q37666135 | ||
| Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase | Q37671387 | ||
| Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible | Q37671503 | ||
| The α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells | Q38735740 | ||
| Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20. | Q38910500 | ||
| Inefficient degradation of cyclin B1 re-activates the spindle checkpoint right after sister chromatid disjunction | Q38931357 | ||
| The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase. | Q39138382 | ||
| Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A. | Q39983420 | ||
| Protein phosphatase 2A and separase form a complex regulated by separase autocleavage | Q40112941 | ||
| Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosis | Q40445615 | ||
| Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. | Q40724282 | ||
| Greatwall maintains mitosis through regulation of PP2A. | Q42115002 | ||
| Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts | Q42563373 | ||
| How APC/C-Cdc20 changes its substrate specificity in mitosis | Q42699227 | ||
| Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase | Q42779085 | ||
| Slow checkpoint activation kinetics as a safety device in anaphase | Q44994898 | ||
| Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts | Q45094598 | ||
| The APC subunit Doc1 promotes recognition of the substrate destruction box. | Q45223003 | ||
| Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2. | Q47071679 | ||
| A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. | Q47071869 | ||
| Dual inhibition of sister chromatid separation at metaphase | Q48873086 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 4 | |
| P304 | page(s) | 484-495 | |
| P577 | publication date | 2015-03-06 | |
| P1433 | published in | Biology Open | Q27724268 |
| P1476 | title | MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C | |
| P478 | volume | 4 |
| Q89982718 | AKT regulates mitotic progression of mammalian cells by phosphorylating MASTL leading to PP2A inactivation |
| Q47636038 | E3 ubiquitin ligases in cancer and implications for therapies |
| Q26740196 | Insights into APC/C: from cellular function to diseases and therapeutics |
| Q59812411 | The Oncogenic Functions of MASTL Kinase |
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