scholarly article | Q13442814 |
P2093 | author name string | Min Li | |
Wenyi Wei | |||
Xiangpeng Dai | |||
Fei Wu | |||
Lixin Wan | |||
Qiang Ding | |||
Jinfang Zhang | |||
Nicholas Mitsiades | |||
Wenjian Gan | |||
P2860 | cites work | Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 | Q24303428 |
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Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. | Q42128896 | ||
Androgen receptor is the key transcriptional mediator of the tumor suppressor SPOP in prostate cancer. | Q42153553 | ||
E2F transcription factors and digestive system malignancies: how much do we know? | Q42772377 | ||
Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase | Q42779085 | ||
Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain. | Q45086646 | ||
APC/CCdh1-dependent degradation of Cdc20 requires a phosphorylation on CRY-box by Polo-like kinase-1 during somatic cell cycle | Q45383374 | ||
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. | Q47071852 | ||
Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20. | Q48863501 | ||
Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation | Q50938485 | ||
Overexpression of Cdc20 in clinically localized prostate cancer: Relation to high Gleason score and biochemical recurrence after laparoscopic radical prostatectomy. | Q52884318 | ||
BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase | Q53633362 | ||
CDC20, a potential cancer therapeutic target, is negatively regulated by p53. | Q55467766 | ||
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation | Q24314520 | ||
SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer | Q24339492 | ||
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase | Q24529056 | ||
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer | Q24616117 | ||
The genomic complexity of primary human prostate cancer | Q24617949 | ||
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer | Q24648025 | ||
Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis | Q26998944 | ||
Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases | Q27027897 | ||
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases | Q27657740 | ||
Function and regulation of cullin-RING ubiquitin ligases | Q28131707 | ||
How proteolysis drives the cell cycle | Q28297983 | ||
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer | Q29616732 | ||
Ubiquitin ligases: cell-cycle control and cancer | Q29617992 | ||
The anaphase promoting complex/cyclosome: a machine designed to destroy | Q29618398 | ||
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. | Q30596621 | ||
Cdc20: a potential novel therapeutic target for cancer treatment | Q33584460 | ||
Identification and validation of genes involved in cervical tumourigenesis | Q33825832 | ||
APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction | Q33842900 | ||
Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p | Q34516234 | ||
Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer | Q34637940 | ||
Cdc20: a WD40 activator for a cell cycle degradation machine | Q34646331 | ||
Preparing to read the ubiquitin code: a middle-out strategy for characterization of all lysine-linked diubiquitins. | Q34650330 | ||
The Molecular Taxonomy of Primary Prostate Cancer | Q34674332 | ||
Roles of F-box proteins in cancer | Q35012352 | ||
Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants | Q35181646 | ||
Targeting Cdc20 as a novel cancer therapeutic strategy | Q35688708 | ||
SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase | Q36278928 | ||
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover | Q36799180 | ||
The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications. | Q37163747 | ||
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase | Q37482039 | ||
MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy | Q38026589 | ||
Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer | Q38314637 | ||
SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. | Q38837458 | ||
Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA | Q39451627 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | protein ubiquitination | Q3547638 |
P304 | page(s) | 207-214 | |
P577 | publication date | 2016-10-22 | |
P1433 | published in | Cancer Letters | Q326372 |
P1476 | title | Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation | |
P478 | volume | 385 |
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Q47413250 | Functional analysis of Cullin 3 E3 ligases in tumorigenesis. |
Q57116830 | Functional roles of Speckle-Type Poz (SPOP) Protein in Genomic stability |
Q47098821 | Identification of SPOP related metabolic pathways in prostate cancer |
Q91713061 | SPOP and cancer: a systematic review |
Q99241388 | SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation |
Q55618243 | SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression. |
Q38834625 | SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein |
Q92487025 | SPOP regulates the DNA damage response and lung adenocarcinoma cell response to radiation |
Q91598898 | SPOP suppresses prostate cancer through regulation of CYCLIN E1 stability |
Q92651169 | The Anaphase Promoting Complex/Cyclosome (APC/C): A Versatile E3 Ubiquitin Ligase |
Q94474488 | The diverse roles of SPOP in prostate cancer and kidney cancer |
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Q53078772 | Uterine function in the mouse requires speckle-type poz protein. |
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