scholarly article | Q13442814 |
P50 | author | Min Wu | Q61190852 |
Y Xiao | Q87824523 | ||
Xinghuan Wang | Q89295104 | ||
Lei Yin | Q42762957 | ||
P2093 | author name string | Lei Zhang | |
Yuan Zhu | |||
Xue-Jing Li | |||
Xiang Lin | |||
Qiao-Yun Long | |||
Shan-Bo Tang | |||
Lin-Gao Ju | |||
Lianyun Li | |||
P2860 | cites work | Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 | Q24303428 |
SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer | Q24339492 | ||
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase | Q24529056 | ||
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer | Q24616117 | ||
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases | Q27657740 | ||
Identification of a novel nuclear speckle-type protein, SPOP | Q28118699 | ||
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line | Q28188152 | ||
Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation | Q28208407 | ||
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase | Q28215069 | ||
Discovery and saturation analysis of cancer genes across 21 tumour types | Q28305204 | ||
Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. | Q51363519 | ||
Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer. | Q51513706 | ||
BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. | Q53633362 | ||
Kinase-independent function of cyclin E | Q79544656 | ||
Kidney cancer: On target - inhibiting SPOP in ccRCC | Q88474604 | ||
The emerging role of speckle-type POZ protein (SPOP) in cancer development | Q34430637 | ||
Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice | Q34537913 | ||
Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer | Q34637940 | ||
Cyclin E deregulation promotes loss of specific genomic regions | Q35630051 | ||
Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation | Q36506569 | ||
Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model | Q36749346 | ||
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover | Q36799180 | ||
A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation | Q36848850 | ||
Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles | Q37011857 | ||
Golgi-associated RhoBTB3 targets cyclin E for ubiquitylation and promotes cell cycle progression | Q37267971 | ||
Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. | Q37373844 | ||
SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing. | Q37577424 | ||
An integrated view of cyclin E function and regulation | Q37970290 | ||
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. | Q38626078 | ||
Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer | Q38705858 | ||
SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. | Q38837458 | ||
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. | Q38838244 | ||
Similar, not the same: diverse roles and regulation of cyclin Es. | Q39388396 | ||
Androgen receptor is the key transcriptional mediator of the tumor suppressor SPOP in prostate cancer. | Q42153553 | ||
Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation | Q42809976 | ||
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. | Q47071852 | ||
Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance | Q47379536 | ||
SPOP-mediated degradation of BRD4 dictates cellular sensitivity to BET inhibitors | Q47435129 | ||
Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. | Q47956425 | ||
Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. | Q47956436 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 6 | |
P921 | main subject | prostate cancer | Q181257 |
P304 | page(s) | 1156-1168 | |
P577 | publication date | 2018-09-20 | |
P1433 | published in | Cell Death & Differentiation | Q2943974 |
P1476 | title | SPOP suppresses prostate cancer through regulation of CYCLIN E1 stability | |
P478 | volume | 26 |