scholarly article | Q13442814 |
P819 | ADS bibcode | 2019NatCo..10.3162W |
P356 | DOI | 10.1038/S41467-019-11224-7 |
P932 | PMC publication ID | 6639328 |
P698 | PubMed publication ID | 31320636 |
P50 | author | Wenyu Wen | Q50233840 |
Qun-Ying Lei | Q54956200 | ||
P2093 | author name string | Zhen Wang | |
Ying Mao | |||
Xing Chen | |||
Jingyu Li | |||
Ziheng Liu | |||
Aihong Gu | |||
Weiyi Yao | |||
Shijing Huang | |||
P2860 | cites work | Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase | Q24292829 |
Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain | Q24338345 | ||
PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
Structural basis of the activation and degradation mechanisms of the E3 ubiquitin ligase Nedd4L | Q27695694 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System | Q28078288 | ||
PhosphoSitePlus, 2014: mutations, PTMs and recalibrations | Q28254001 | ||
The ubiquitin code | Q28265104 | ||
Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer | Q28266601 | ||
Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation | Q28510102 | ||
Physiological functions of the HECT family of ubiquitin ligases | Q29617293 | ||
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer | Q30525287 | ||
ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis | Q33719411 | ||
Peptide and small molecule inhibitors of HECT-type ubiquitin ligases | Q34601308 | ||
Macromolecular juggling by ubiquitylation enzymes | Q34782977 | ||
Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. | Q35619339 | ||
System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes | Q35947378 | ||
Protein tyrosine kinase-substrate interactions | Q36644933 | ||
The HECT family of E3 ubiquitin ligases: multiple players in cancer development | Q37206488 | ||
COSMIC: somatic cancer genetics at high-resolution | Q37556877 | ||
The role of ubiquitylation in nerve cell development | Q37866988 | ||
WWP1: a versatile ubiquitin E3 ligase in signaling and diseases | Q37952498 | ||
New insights into ubiquitin E3 ligase mechanism | Q38201970 | ||
Structural insights into the catalysis and regulation of E3 ubiquitin ligases | Q38916854 | ||
Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer | Q39006737 | ||
Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases. | Q39030641 | ||
Ubiquitin Ligases: Structure, Function, and Regulation. | Q39219103 | ||
WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis | Q39937434 | ||
The amplified WWP1 gene is a potential molecular target in breast cancer | Q40165059 | ||
p63 regulates an adhesion programme and cell survival in epithelial cells | Q40277208 | ||
A conformational switch regulates the ubiquitin ligase HUWE1. | Q42321543 | ||
The -4 phenylalanine is required for substrate ubiquitination catalyzed by HECT ubiquitin ligases | Q44765720 | ||
Ubiquitin ligases in oncogenic transformation and cancer therapy | Q46609299 | ||
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia | Q47326031 | ||
E3 ubiquitin ligases in cancer and implications for therapies | Q47636038 | ||
Targeting HECT-type E3 ligases - insights from catalysis, regulation and inhibitors. | Q47995331 | ||
Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch. | Q48178072 | ||
Structural and functional framework for the autoinhibition of Nedd4-family ubiquitin ligases. | Q50620786 | ||
A Tunable Brake for HECT Ubiquitin Ligases. | Q51018317 | ||
Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity. | Q55070815 | ||
Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140 | Q58594221 | ||
Developing Small-Molecule Inhibitors of HECT-Type Ubiquitin Ligases for Therapeutic Applications: Challenges and Opportunities | Q58837454 | ||
The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR. | Q64954353 | ||
Regulating the human HECT E3 ligases. | Q64992613 | ||
Physiological Functions of Nedd4-2: Lessons from Knockout Mouse Models | Q90595305 | ||
WW domain-mediated regulation and activation of E3 ubiquitin ligase Suppressor of Deltex | Q91435604 | ||
GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers | Q104439794 | ||
P433 | issue | 1 | |
P304 | page(s) | 3162 | |
P577 | publication date | 2019-07-18 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases | |
P478 | volume | 10 |
Search more.