Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit

scientific article

Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.25.23.10516-10527.2005
P8608Fatcat IDrelease_mnpdos6nzbbv3dasdhsp6nd4q4
P3181OpenCitations bibliographic resource ID100857
P932PMC publication ID1291225
P698PubMed publication ID16287863

P2093author name stringScott Stewart
Guowei Fang
P2860cites workGeneration of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formationQ22010265
E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)Q24296663
Structural basis of Aurora-A activation by TPX2 at the mitotic spindleQ24298490
Mitotic regulation of the human anaphase-promoting complex by phosphorylationQ24301075
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1Q24608202
Human TPX2 is required for targeting Aurora-A kinase to the spindleQ24671169
The ubiquitin systemQ27860803
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.Q27930914
Cyclin is degraded by the ubiquitin pathwayQ28131704
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complexQ28199187
Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cellsQ28208657
hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell divisionQ28217184
Cell cycle regulation by the ubiquitin pathwayQ28254425
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1Q28282074
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteinsQ28343954
The anaphase-promoting complex: proteolysis in mitosis and beyondQ28610045
Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregationQ30484703
Subunits and substrates of the anaphase-promoting complexQ33604656
Control of mitotic transitions by the anaphase-promoting complexQ33785051
The anaphase-promoting complex: it's not just for mitosis any more.Q34147374
Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20pQ34516234
Cyclin synthesis drives the early embryonic cell cycleQ34667885
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complexQ35081283
Aurora A on the mitotic spindle is activated by the way it holds its partner.Q35568835
Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exitQ35787361
Mitotic degradation of human thymidine kinase 1 is dependent on the anaphase-promoting complex/cyclosome-CDH1-mediated pathwayQ36222297
The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phaseQ41077459
Mechanisms and regulation of ubiquitin-mediated cyclin degradation.Q41154851
Roles of ubiquitin-mediated proteolysis in cell cycle controlQ41678499
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extractsQ43940269
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.Q50719496
The ran GTPase regulates mitotic spindle assembly.Q52535025
Regulation ofXenopusAurora A Activation by TPX2Q60017623
A novel mechanism for activation of the protein kinase Aurora AQ73280786
Stimulation of microtubule aster formation and spindle assembly by the small GTPase RanQ77767632
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assemblyQ78954671
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)10516-27
P577publication date2005-12-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleAnaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit
P478volume25

Reverse relations

cites work (P2860)
Q24321340A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2
Q28072560APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathway
Q37799221APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity
Q41299284An in vivo study of Cdh1/APC in breast cancer formation.
Q83099487Anaphase-promoting complex/cyclosome controls HEC1 stability
Q93382078Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
Q24318410Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
Q34610953CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit
Q30418144Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells
Q42852173Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase
Q52659538CoA synthase regulates mitotic fidelity via CBP-mediated acetylation.
Q39621507Control of Aurora-A stability through interaction with TPX2.
Q30491013Detection of Significant Pneumococcal Meningitis Biomarkers by Ego Network
Q91033236Distribution of Eg5 and TPX2 in mitosis: Insight from CRISPR tagged cells
Q30489286Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase
Q47636038E3 ubiquitin ligases in cancer and implications for therapies
Q35770195Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control.
Q89633452Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit
Q51508722Genome wide expression analysis of radiation-induced DNA damage responses in isogenic HCT116 p53+/+ and HCT116 p53-/- colorectal carcinoma cell lines.
Q33589959ISWI is a RanGTP-dependent MAP required for chromosome segregation
Q26740196Insights into APC/C: from cellular function to diseases and therapeutics
Q27438173Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes
Q30572037Microtubule-dependent regulation of mitotic protein degradation.
Q36796428Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2.
Q24648791Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
Q42912173Nonparametric Bayesian evaluation of differential protein quantification
Q35580856Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly
Q33352664Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication
Q28115063Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression
Q37863285Processive ubiquitin chain formation by the anaphase-promoting complex.
Q90136175Prognostic significance of TOP2A in non-small cell lung cancer revealed by bioinformatic analysis
Q36869895RCS1, a substrate of APC/C, controls the metaphase to anaphase transition
Q40966374Regulated degradation of spindle assembly factors by the anaphase-promoting complex.
Q36394421Regulation of APC/C-Cdh1 and its function in neuronal survival
Q36734913Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis
Q33952810Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2
Q24646873Spindle pole regulation by a discrete Eg5-interacting domain in TPX2
Q35186944Substrate degradation by the anaphase promoting complex occurs during mitotic slippage
Q36825650TPX2 in human clear cell renal carcinoma: Expression, function and prognostic significance
Q37426758TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer
Q36117589TPX2 is required for postmitotic nuclear assembly in cell-free Xenopus laevis egg extracts
Q38189984TPX2: of spindle assembly, DNA damage response, and cancer
Q37614211The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression
Q21203555The function of APC/CCdh1 in cell cycle and beyond
Q43453161The plant TPX2 protein regulates prospindle assembly before nuclear envelope breakdown
Q33337164The spindle function of CDCA4.
Q27318159Urochordate ascidians possess a single isoform of Aurora kinase that localizes to the midbody via TPX2 in eggs and cleavage stage embryos
Q36762845Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability.

Search more.