| review article | Q7318358 |
| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2002Sci...296.1646A |
| P356 | DOI | 10.1126/SCIENCE.1071809 |
| P3181 | OpenCitations bibliographic resource ID | 1091617 |
| P698 | PubMed publication ID | 12040180 |
| P50 | author | Jeffrey L. Wrana | Q92537055 |
| P2093 | author name string | Liliana Attisano | |
| P433 | issue | 5573 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1646-7 | |
| P577 | publication date | 2002-05-31 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Signal transduction by the TGF-beta superfamily | |
| P478 | volume | 296 |
| Q64287660 | A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice |
| Q35095530 | A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells |
| Q35001957 | A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling |
| Q51863324 | A detailed analysis of 3D subcellular signal localization. |
| Q47431967 | A novel 62-bp indel mutation in the promoter region of transforming growth factor-beta 2 (TGFB2) gene is associated with body weight in chickens |
| Q42412062 | A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor |
| Q34761291 | A role of TGFß1 dependent 14-3-3σ phosphorylation at Ser69 and Ser74 in the regulation of gene transcription, stemness and radioresistance |
| Q33509682 | A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog |
| Q44828936 | ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm induction in Xenopus |
| Q34592831 | ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells. |
| Q36471312 | Accessory cell populations in the cornea |
| Q40676346 | Activated beta-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2 mediated signal transduction |
| Q37700520 | Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis |
| Q34621755 | Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling. |
| Q35961430 | Activation of the BMP-BMPR pathway conferred resistance to EGFR-TKIs in lung squamous cell carcinoma patients with EGFR mutations |
| Q39664271 | Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells |
| Q33458604 | Activin A is essential for neurogenesis following neurodegeneration |
| Q34099993 | Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements. |
| Q28589210 | Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1 |
| Q36186814 | Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery |
| Q34463886 | Adenovirus-mediated gene transfer of mutated IkappaB kinase and IkappaBalpha reveal NF-kappaB-dependent as well as NF-kappaB-independent pathways of HAS1 activation |
| Q46292174 | Adsorption of enamel matrix proteins to a bovine-derived bone grafting material and its regulation of cell adhesion, proliferation, and differentiation |
| Q34734393 | Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. |
| Q28571613 | Albumin endocytosis in endothelial cells induces TGF-beta receptor II signaling |
| Q83320051 | Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma |
| Q57259102 | Alterations of blood IL-8, TGF-β1 and nitric oxide levels in relation to blood cells in patients with acute brain injury |
| Q40597763 | Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. |
| Q30475524 | Amygdalocortical circuitry in schizophrenia: from circuits to molecules |
| Q92535998 | Angiogenic Transformation in Human Brain Micro Endothelial Cells: Whole Genome DNA Methylation and Transcriptomic Analysis |
| Q48503079 | Anthocyanidins inhibit epithelial-mesenchymal transition through a TGFβ/Smad2 signaling pathway in glioblastoma cells |
| Q39372162 | Anti-TGF-β1 Antibody Therapy in Patients with Diabetic Nephropathy. |
| Q40565674 | Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP. |
| Q54357735 | Association of polymorphisms in transforming growth factor-β receptors with susceptibility to gastric cardia adenocarcinoma. |
| Q37112637 | Association of v-ErbA with Smad4 disrupts TGF-beta signaling. |
| Q37969565 | Atrial remodeling in atrial fibrillation and some related microRNAs |
| Q42664400 | Autoimmune pancreatitis results from loss of TGFbeta signalling in S100A4-positive dendritic cells |
| Q37110142 | Axin1 and Axin2 are regulated by TGF- and mediate cross-talk between TGF- and Wnt signaling pathways. |
| Q29614624 | BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3 |
| Q36498604 | BMP signaling in mesenchymal stem cell differentiation and bone formation |
| Q47866973 | BMP-2 regulates cardiomyocyte contractility in a phosphatidylinositol 3 kinase-dependent manner |
| Q44479221 | BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury |
| Q37084834 | BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling |
| Q39786691 | BMP2 accelerates the motility and invasiveness of gastric cancer cells via activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway |
| Q36796379 | BMP9 signaling in stem cell differentiation and osteogenesis |
| Q33849207 | Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies |
| Q26746964 | Bone Morphogenetic Protein 4 Signalling in Neural Stem and Progenitor Cells during Development and after Injury |
| Q64265402 | Bone Morphogenetic Protein-6 Attenuates Type 1 Diabetes Mellitus-Associated Bone Loss |
| Q41257795 | Bone Morphogenetic Protein-7 Antagonizes Myocardial Fibrosis Induced by Atrial Fibrillation by Restraining Transforming Growth Factor-β (TGF-β)/Smads Signaling. |
| Q37524243 | Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling |
| Q30485381 | Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. |
| Q35111137 | Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation |
| Q42025588 | Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes |
| Q39164711 | Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines |
| Q46024971 | Bone morphogenetic protein-7 signals opposing transforming growth factor beta in mesangial cells. |
| Q38066205 | Bone morphogenetic proteins in craniofacial surgery: current techniques, clinical experiences, and the future of personalized stem cell therapy |
| Q42491392 | Bone morphogenetic proteins regulate neural tube closure by interacting with the apicobasal polarity pathway |
| Q35217926 | Brassinosteroids signal through two receptor-like kinases |
| Q35084316 | Breast cancer as a model of realistic challenges in pharmacogenomics |
| Q89553060 | C20orf27 Promotes Cell Growth and Proliferation of Colorectal Cancer via the TGFβR-TAK1-NFĸB Pathway |
| Q37649103 | CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice |
| Q39205717 | Ca2+/S100 proteins act as upstream regulators of the chaperone-associated ubiquitin ligase CHIP (C terminus of Hsc70-interacting protein) |
| Q36112384 | Caenorhabditis elegans opens up new insights into circadian clock mechanisms |
| Q38931945 | Cardiac Embryology and Molecular Mechanisms of Congenital Heart Disease: A Primer for Anesthesiologists |
| Q34684837 | Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy |
| Q26739070 | Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers |
| Q89819997 | Caveolin-1 Impacts on TGF-β Regulation of Metabolic Gene Signatures in Hepatocytes |
| Q47829407 | Cdc42-interacting protein 4 silencing relieves pulmonary fibrosis in STZ-induced diabetic mice via the Wnt/GSK-3β/β-catenin pathway. |
| Q80543404 | Cell biology: an unexpected social servant |
| Q37749618 | Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions. |
| Q37848468 | Cellular/extracellular matrix cross-talk in scar evolution and control. |
| Q48236427 | Cerebellar deficits and hyperactivity in mice lacking Smad4. |
| Q38680851 | Chi-miR-4110 promotes granulosa cell apoptosis by targeting Sma- and Mad-related protein 2 (Smad2) in the caprine ovary. |
| Q37618856 | Chinese herbal medicine on dyslipidemia: progress and perspective |
| Q46867288 | Chymase induces profibrotic response via transforming growth factor-beta 1/Smad activation in rat cardiac fibroblasts |
| Q35108385 | Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia |
| Q36861023 | Clinical, agricultural, and evolutionary biology of myostatin: a comparative review |
| Q35973726 | Clinicopathological significance of BMP7 expression in esophageal squamous cell carcinoma |
| Q37012626 | Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis |
| Q47369000 | Comparative proteomic analysis of amnion membrane transplantation and cross-linking treatments in an experimental alkali injury model. |
| Q35148901 | Comparison of efficacy of the disease-specific LOX1- and constitutive cytomegalovirus-promoters in expressing interleukin 10 through adeno-associated virus 2/8 delivery in atherosclerotic mice |
| Q28566104 | Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays |
| Q51635782 | Computational analysis on conformational dynamics of bone morphogenetic protein-2 (BMP-2). |
| Q45074221 | Concordant repression and aberrant methylation of transforming growth factor-beta signaling pathway genes occurs early in gastric cardia adenocarcinoma |
| Q38724559 | Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling |
| Q34453805 | Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function |
| Q34572125 | Constitutively active FOXO1 diminishes activin induction of Fshb transcription in immortalized gonadotropes |
| Q36119870 | Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors |
| Q64068044 | Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation |
| Q52106477 | Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. |
| Q24319810 | Cooperation between TGF-beta and Wnt pathways during chondrocyte and adipocyte differentiation of human marrow stromal cells |
| Q57281644 | Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk |
| Q64227138 | Correlations between the polymorphism of +869T/C in TGF-β1 and rheumatoid arthritis |
| Q27664978 | Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity |
| Q33985637 | Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells |
| Q28580123 | Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells |
| Q24672178 | Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3 |
| Q27656258 | Crystal structure of the MH2 domain of Drosophila Mad |
| Q42803740 | CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression |
| Q38935426 | Curcumin induces differential expression of cytoprotective enzymes but similar apoptotic responses in fibroblasts and myofibroblasts |
| Q49957735 | Current and emerging therapies for PNETs in patients with or without MEN1. |
| Q37817045 | Current concepts in scar evolution and control |
| Q30479504 | Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubules |
| Q28569402 | Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokines |
| Q37688671 | Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF-β signaling pathway |
| Q28281152 | Cytoplasmic PML function in TGF-beta signalling |
| Q62391089 | Cytotoxicological pathways induced after nanoparticle exposure: studies of oxidative stress at the 'nano-bio' interface |
| Q24296908 | DACH1 inhibits transforming growth factor-beta signaling through binding Smad4 |
| Q36104501 | DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. |
| Q28511586 | DMH1, a small molecule inhibitor of BMP type i receptors, suppresses growth and invasion of lung cancer |
| Q24292739 | DRAGON, a bone morphogenetic protein co-receptor |
| Q64989029 | Deciphering the SUMO code in the kidney. |
| Q36020284 | Decreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice. |
| Q34700590 | Defective osteogenic differentiation in the development of osteosarcoma |
| Q37706364 | Deregulation of bone forming cells in bone diseases and anabolic effects of strontium-containing agents and biomaterials |
| Q36672276 | Development and differentiation of neural rosettes derived from human embryonic stem cells |
| Q37349206 | Diabetes and Kidney Disease: Role of Oxidative Stress |
| Q30436708 | Different domains regulate homomeric and heteromeric complex formation among type I and type II transforming growth factor-beta receptors |
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| Q40633830 | Differential activation of the luteinizing hormone beta-subunit promoter by activin and gonadotropin-releasing hormone: a role for the mitogen-activated protein kinase signaling pathway in LbetaT2 gonadotrophs. |
| Q44693918 | Differential effect of transforming growth factor beta (TGF-beta) on the genes encoding hyaluronan synthases and utilization of the p38 MAPK pathway in TGF-beta-induced hyaluronan synthase 1 activation |
| Q38709655 | Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling |
| Q24297637 | Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4 |
| Q40537092 | Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis |
| Q48229042 | Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cells. |
| Q21284174 | Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1 |
| Q40124427 | Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation |
| Q36959467 | Dissecting the role of transforming growth factor-β1 in topmouth culter immunobiological activity: a fundamental functional analysis |
| Q42474780 | Distribution of mRNAs encoding transforming growth factors-beta1, -2, and -3 in the intact rat brain and after experimentally induced focal ischemia |
| Q33505662 | Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors |
| Q53376881 | Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. |
| Q38685123 | Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly. |
| Q35663498 | Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways |
| Q33830232 | Downregulation of TGF-beta receptor types II and III in oral squamous cell carcinoma and oral carcinoma-associated fibroblasts |
| Q35641680 | Dual role of SnoN in mammalian tumorigenesis |
| Q33286384 | Duplexed, bead-based competitive assay for inhibitors of protein kinases |
| Q42408221 | Dynamic decapentaplegic signaling regulates patterning and adhesion in the Drosophila pupal retina |
| Q38038526 | Dynamic regulation of cancer stem cells and clinical challenges |
| Q47636038 | E3 ubiquitin ligases in cancer and implications for therapies |
| Q35715849 | EGFR signaling promotes TGFβ-dependent renal fibrosis |
| Q91933381 | ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendons |
| Q39724790 | Early oral ovalbumin exposure during maternal milk feeding prevents spontaneous allergic sensitization in allergy-prone rat pups |
| Q44360253 | Editorial commentary: SMAD expression in the testis predicts age- and cell-specific responses to activin and TGFbeta |
| Q36583492 | Effect of TGF-β1 on the Migration and Recruitment of Mesenchymal Stem Cells after Vascular Balloon Injury: Involvement of Matrix Metalloproteinase-14. |
| Q41204602 | Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbfα-1 pathway |
| Q40650780 | Effect of transforming growth factor-beta on calcium homeostasis in prostate carcinoma cells. |
| Q31158693 | Effects of Chinese traditional compound, JinSanE, on expression of TGF-beta1 and TGF-beta1 type II receptor mRNA, Smad3 and Smad7 on experimental hepatic fibrosis in vivo |
| Q48599185 | Effects of Smad3 on the proliferation and steroidogenesis in human ovarian luteinized granulosa cells |
| Q44576958 | Effects of kinase inhibitors on TGF-beta induced upregulation of Kv1.3 K+ channels in brain macrophages |
| Q54426098 | Effects of low-intensity pulsed ultrasound, dexamethasone/TGF-beta1 and/or BMP-2 on the transcriptional expression of genes in human mesenchymal stem cells: chondrogenic vs. osteogenic differentiation. |
| Q37295226 | Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis |
| Q41460250 | Embryonic liver fordin is involved in glucose glycolysis of hepatic stellate cell by regulating PI3K/Akt signaling |
| Q38928611 | Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition |
| Q40902696 | Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. |
| Q33802356 | Epigenetic Targeting of Transforming Growth Factor β Receptor II and Implications for Cancer Therapy |
| Q50449883 | Epithelial, mesenchymal and hybrid epithelial/mesenchymal phenotypes and their clinical relevance in cancer metastasis. |
| Q37621666 | Epithelial-mesenchymal Transition---A Hallmark of Breast Cancer Metastasis |
| Q42928789 | Epithelial-mesenchymal transition - activating transcription factors - multifunctional regulators in cancer |
| Q24302042 | Epithelial-mesenchymal transition and its implications for fibrosis |
| Q36986452 | Epithelial-mesenchymal transition in breast cancer progression and metastasis |
| Q36574632 | Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a |
| Q38271582 | Evolutionary roots of arginase expression and regulation |
| Q39387507 | Expression and purification of recombinant protein related to DAN and cerberus (PRDC). |
| Q42607432 | Expression of Smad ubiquitin regulatory factor 2 (Smurf2) in rhesus monkey endometrium and placenta during early pregnancy |
| Q80094000 | Expression of angiotensin II receptor type 1 is reduced in advanced rat liver fibrosis |
| Q50662648 | Expression of latent transforming growth factor beta binding proteins in the rat brain. |
| Q37189687 | Extracellular matrix-induced gene expression in human breast cancer cells |
| Q39748004 | Extracellular matrix-induced transforming growth factor-beta receptor signaling dynamics |
| Q35872743 | FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone β-subunit promoter |
| Q51759559 | Fenofibrate attenuates diabetic nephropathy in experimental diabetic rat's model via suppression of augmented TGF-β1/Smad3 signaling pathway. |
| Q37847632 | Fibroblasts and myofibroblasts in renal fibrosis |
| Q53656434 | Fibroblasts from chronic wounds show altered TGF‐β‐signaling and decreased TGF‐β Type II Receptor expression |
| Q35908533 | FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc |
| Q33853091 | FoxL2 Is required for activin induction of the mouse and human follicle-stimulating hormone beta-subunit genes. |
| Q24655444 | FoxL2 and Smad3 coordinately regulate follistatin gene transcription |
| Q28594922 | Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development |
| Q33843619 | Foxp3 positive regulatory T cells: a functional regulation by the E3 ubiquitin ligase Itch |
| Q30479523 | Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity |
| Q24298398 | Functional proteomics mapping of a human signaling pathway |
| Q47223756 | Functional role of AKT signaling in bovine early embryonic development: potential link to embryotrophic actions of follistatin |
| Q24676599 | GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor |
| Q91011710 | Gadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis |
| Q92593543 | Galanthamine improves myocardial ischemia-reperfusion-induced cardiac dysfunction, endoplasmic reticulum stress-related apoptosis, and myocardial fibrosis by suppressing AMPK/Nrf2 pathway in rats |
| Q39176003 | Gdf6 induces commitment of pluripotent mesenchymal C3H10T1/2 cells to the adipocyte lineage |
| Q34548935 | Gene expression profiling reveals Cyp26b1 to be an activin regulated gene involved in ovarian granulosa cell proliferation |
| Q33992203 | Genetic evidence that SMAD2 is not required for gonadal tumor development in inhibin-deficient mice |
| Q43192139 | Getting Old through the Blood: Circulating Molecules in Aging and Senescence of Cardiovascular Regenerative Cells |
| Q44512671 | Glucose-dependent insulinotropic peptide stimulates proliferation and TGF-beta release from MG-63 cells. |
| Q37388116 | Grape seed extract attenuates arsenic-induced nephrotoxicity in rats |
| Q91634645 | Growth differentiation factor 11 inhibits adipogenic differentiation by activating TGF-beta/Smad signalling pathway |
| Q51797614 | Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. |
| Q61895074 | Génétique et HTAP : de la physiopathologie à la clinique |
| Q49724466 | HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer |
| Q39315260 | Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells. |
| Q34140466 | Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway |
| Q30838496 | Hereditary haemorrhagic telangiectasia treated by pulsed neodymium:yttrium-aluminium-garnet (Nd:YAG) laser (1,064 nm). |
| Q39798550 | Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells |
| Q24655929 | Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells |
| Q42024077 | High concentrations of mast cell chymase facilitate the transduction of the transforming growth factor-β1/Smads signaling pathway in skin fibroblasts |
| Q35878285 | High-Efficiency Induction of Neural Conversion in Human ESCs and Human Induced Pluripotent Stem Cells with a Single Chemical Inhibitor of Transforming Growth Factor Beta Superfamily Receptors |
| Q90672666 | Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism |
| Q33237082 | Highly sensitive and specific bioassay for measuring bioactive TGF-beta |
| Q44504015 | Highwire regulates presynaptic BMP signaling essential for synaptic growth. |
| Q36084443 | Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs |
| Q33625226 | Hormones in synergy: regulation of the pituitary gonadotropin genes. |
| Q39353206 | Houttuynia cordata inhibits lipopolysaccharide-induced rapid pulmonary fibrosis by up-regulating IFN-γ and inhibiting the TGF-β1/Smad pathway |
| Q54569461 | Human eosinophils have an intact Smad signaling pathway leading to a major transforming growth factor-beta target gene expression. |
| Q35232951 | Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channels |
| Q46824105 | Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation |
| Q42733192 | Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction |
| Q47794569 | Hydrogen peroxide-induced cellular apoptosis is mediated by TGF-beta2 signaling pathway in cultured human lens epithelial cells |
| Q37142258 | Hypermethylation of TGF-β1 gene promoter in gastric cancer |
| Q36842393 | IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis. |
| Q40649535 | IL-18 and IL-12 Signal Through the NF-κB Pathway to Induce NK-1R Expression on T Cells |
| Q33720280 | IRE1a constitutes a negative feedback loop with BMP2 and acts as a novel mediator in modulating osteogenic differentiation |
| Q36767882 | Identification and association of TGFβ-1 expression in patients with asthma in a Polish population - Lodz metropolitan area study |
| Q34121834 | Identification and association of the single nucleotide polymorphisms, C-509T, C+466T and T+869C, of the TGF-β1 gene in patients with asthma and their influence on the mRNA expression level of TGF-β1 |
| Q34898379 | Identification and functional characterization of NODAL rare variants in heterotaxy and isolated cardiovascular malformations |
| Q23910071 | Identification of TGF-beta receptor-1 as a key regulator of carbon nanotube-induced fibrogenesis |
| Q39279137 | Identification of a novel bone morphogenetic protein (BMP)-inducible transcript, BMP-inducible transcript-1, by utilizing the conserved BMP-responsive elements in the Id genes |
| Q24540250 | Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1. |
| Q34477628 | Identification of phosphatases for Smad in the BMP/DPP pathway |
| Q38351396 | Identification of target genes of the p16INK4A-pRB-E2F pathway. |
| Q35125625 | In or out? The dynamics of Smad nucleocytoplasmic shuttling |
| Q42832730 | Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions. |
| Q40586304 | Indian hedgehog gene is a target of the bone morphogenetic protein signaling pathway |
| Q38107885 | Induced pluripotency and direct reprogramming: a new window for treatment of neurodegenerative diseases |
| Q35068973 | Induction and patterning of neuronal development, and its connection to cell cycle control |
| Q35128563 | Induction of TGF-beta1 in the trabecular meshwork under cyclic mechanical stress |
| Q34204531 | Inhibin at 90: from discovery to clinical application, a historical review |
| Q35064307 | Inhibins and activins: clinical advances in reproductive medicine |
| Q35980393 | Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death |
| Q38829813 | Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression |
| Q40456120 | Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis. |
| Q36927604 | Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis. |
| Q37037947 | Inhibition of transforming growth factor-beta/Smad signaling by phosphatidylinositol 3-kinase pathway |
| Q57066646 | Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension |
| Q54400972 | Inhibitory effect of ethyl acetate extract of Aristolochia yunnanensis on cardiac fibrosis through extracellular signal-regulated kinases 1/2 and transforming growth factor β/small mother against decapentaplegic signaling pathways. |
| Q35229856 | Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation |
| Q41104764 | Int7G24A polymorphism (rs334354) and cancer risk |
| Q35103548 | Interferon-gamma protects against chronic viral myocarditis by reducing mast cell degranulation, fibrosis, and the profibrotic cytokines transforming growth factor-beta 1, interleukin-1 beta, and interleukin-4 in the heart |
| Q28584224 | Involvement of Protein Kinase C-Dependent Mitogen-Activated Protein Kinase p44/42 Signaling Pathway for Cross-Talk between Estradiol and Transforming Growth Factor-β3 in Increasing Basic Fibroblast Growth Factor in Folliculostellate Cells |
| Q40398134 | Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation |
| Q54567736 | JinSanE decoction, a chinese herbal medicine, inhibits expression of TGF-beta1/Smads in experimental hepatic fibrosis in rats. |
| Q51780933 | Juvenile polyps have gastric differentiation with MUC5AC expression and downregulation of CDX2 and SMAD4. |
| Q92308392 | Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway |
| Q34130322 | Keratocan expression of murine keratocytes is maintained on amniotic membrane by down-regulating transforming growth factor-beta signaling. |
| Q36853486 | Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation |
| Q35098314 | Kinetics of gene expression in murine cutaneous graft-versus-host disease |
| Q36978251 | LOXL4 is induced by transforming growth factor β1 through Smad and JunB/Fra2 and contributes to vascular matrix remodeling. |
| Q39241021 | Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis |
| Q39932939 | Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling. |
| Q39628060 | Latent TGF-β binding proteins (LTBPs) 1 and 3 differentially regulate transforming growth factor-β activity in malignant mesothelioma |
| Q33609106 | Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3 |
| Q63322965 | Liver regeneration |
| Q50053071 | LncRNA MALAT1 regulates smooth muscle cell phenotype switch via activation of autophagy |
| Q52000197 | Localization of TGF-beta signaling intermediates Smad2, 3, 4, and 7 in developing and mature human and mouse kidney. |
| Q54762579 | Loss of expression, and mutations of Smad 2 and Smad 4 in human cervical cancer. |
| Q34012419 | Low gene expression of bone morphogenetic protein 7 in brainstem astrocytes in major depression |
| Q43171141 | Low-Intensity Ultrasound (LIUS) as an Innovative Tool for Chondrogenesis of Mesenchymal Stem Cells (MSCs). |
| Q51140686 | Low-intensity ultrasound stimulation enhances chondrogenic differentiation in alginate culture of mesenchymal stem cells. |
| Q40330923 | MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer |
| Q64115759 | MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression |
| Q35756439 | Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles. |
| Q34028883 | Mast cell chymase in keloid induces profibrotic response via transforming growth factor-β1/Smad activation in keloid fibroblasts |
| Q36346393 | Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching. |
| Q50746835 | Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence. |
| Q92366574 | Mechanism of epithelial‑mesenchymal transition inhibited by miR‑203 in non‑small cell lung cancer |
| Q53357289 | Mechanism of protective effect of phyllanthin against carbon tetrachloride-induced hepatotoxicity and experimental liver fibrosis in mice. |
| Q35185712 | Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling. |
| Q26750626 | Meeting the meat: delineating the molecular machinery of muscle development |
| Q50075575 | Melatonin promotes self-renewal of nestin-positive pancreatic stem cells through activation of the MT2/ERK/SMAD/nestin axis |
| Q37395883 | Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer |
| Q84098237 | Metastatic function of BMP-2 in gastric cancer cells: the role of PI3K/AKT, MAPK, the NF-κB pathway, and MMP-9 expression |
| Q36248454 | Methylation and Expression of Retinoblastoma and Transforming Growth Factor-β1 Genes in Epstein-Barr Virus-Associated and -Negative Gastric Carcinomas |
| Q39932854 | MiR-125b Regulates Primordial Follicle Assembly by Targeting Activin Receptor Type 2a in Neonatal Mouse Ovary |
| Q33990587 | MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis |
| Q36772647 | Microfluidic artificial "vessels" for dynamic mechanical stimulation of mesenchymal stem cells |
| Q55364205 | Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment. |
| Q39736479 | Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation |
| Q26765017 | Modeling congenital disease and inborn errors of development in Drosophila melanogaster |
| Q28083441 | Modifier genes and their effect on Duchenne muscular dystrophy |
| Q27667356 | Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP) |
| Q50043553 | Molecular Regulation of Follicle-Stimulating Hormone Synthesis, Secretion and Action |
| Q38117036 | Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: potential benefits for wound healing |
| Q38588243 | Molecular basis of differentiation therapy for soft tissue sarcomas |
| Q52588859 | Molecular changes during TGFβ-mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance. |
| Q37847515 | Molecular cross-regulation between PPAR-γ and other signaling pathways: implications for lung cancer therapy. |
| Q34161204 | Morphogen gradients, positional information, and Xenopus: interplay of theory and experiment. |
| Q39284951 | Multi-Harmony: detecting functional specificity from sequence alignment. |
| Q24296798 | Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2 |
| Q24296422 | Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis |
| Q37594117 | Myostatin stimulates, not inihibits, C2C12 myoblast proliferation. |
| Q36508803 | Myotubularin-related protein 4 (MTMR4) attenuates BMP/Dpp signaling by dephosphorylation of Smad proteins |
| Q33562191 | NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts |
| Q40607119 | Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling. |
| Q41669132 | Neurovascular patterning cues and implications for central and peripheral neurological disease |
| Q57059663 | New player in endosomal trafficking: Differential roles of Smad Anchor for Receptor Activation (SARA) protein |
| Q36924251 | Nimodipine rescues N-methyl-N-nitrosourea-induced retinal degeneration in rats |
| Q35750204 | Nitric oxide and other novel therapies for pulmonary hypertension |
| Q84292681 | Nitric oxide and pulmonary hypertension |
| Q34271462 | Nodal Signaling in Vertebrate Development |
| Q42143642 | Nodal and activin receptor-like kinase 7 induce apoptosis in human breast cancer cell lines: Role of caspase 3. |
| Q36114856 | Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells |
| Q38304615 | Nodal signaling activates differentiation genes during zebrafish gastrulation |
| Q46126542 | Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells |
| Q38519494 | Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-beta activity through the inhibition of Smad signaling pathway. |
| Q28183042 | Normal reproductive function in InhBP/p120-deficient mice |
| Q36609701 | Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells |
| Q52603777 | Novel bone morphogenetic protein receptor inhibitor JL5 suppresses tumor cell survival signaling and induces regression of human lung cancer. |
| Q88615700 | Nuclear Transport and Accumulation of Smad Proteins Studied by Single-Molecule Microscopy |
| Q35831988 | Nuclear lamins: key regulators of nuclear structure and activities |
| Q24299213 | Nuclear targeting of transforming growth factor-beta-activated Smad complexes |
| Q28288378 | OAZ regulates bone morphogenetic protein signaling through Smad6 activation |
| Q28067777 | Ockham's razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer |
| Q36939314 | Olfactory epithelium progenitors: insights from transgenic mice and in vitro biology |
| Q37743980 | Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression |
| Q51071341 | Optimization of culture conditions for stem cells derived from human anterior cruciate ligament and bone marrow. |
| Q39342955 | Overexpression of Smad ubiquitin regulatory factor 2 suppresses transforming growth factor-β mediated liver fibrosis |
| Q53247182 | PAR2-SMAD3 in microvascular endothelial cells is indispensable for vascular stability via tissue factor signaling. |
| Q40572600 | PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3. |
| Q38189168 | PML tumour suppression and beyond: therapeutic implications |
| Q44074349 | PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster |
| Q36177028 | Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling |
| Q28209990 | Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2 |
| Q42196968 | Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling |
| Q40390538 | Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin |
| Q38846454 | Periostin as a multifunctional modulator of the wound healing response |
| Q41144730 | Peroxisome proliferator activated receptor-γ and the ubiquitin-proteasome system in colorectal cancer |
| Q35998820 | PfSMAD4 plays a role in biomineralization and can transduce bone morphogenetic protein-2 signals in the pearl oyster Pinctada fucata |
| Q39594881 | Phospho-Smad1 modulation by nedd4 E3 ligase in BMP/TGF-β signaling |
| Q54110501 | Physical interaction of STAT1 isoforms with TGF-β receptors leads to functional crosstalk between two signaling pathways in epithelial ovarian cancer. |
| Q33581891 | Pin1 promotes transforming growth factor-beta-induced migration and invasion |
| Q58087062 | Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation |
| Q39343299 | Possible novel roles of poly(rC)-binding protein 1 in SH-SY5Y neurocytes: an analysis using a dynamic Bayesian network |
| Q36168476 | Potential of proteomics towards the investigation of the IGF-independent actions of IGFBP-3. |
| Q49716199 | Preliminary Study of the Role F-Box Protein 32 (FBXO32) in Colorectal Neoplasms Through the Transforming Growth Factor beta (TGF-β)/Smad4 Signalling Pathway. |
| Q34560071 | Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology |
| Q51535376 | Prognostic significance of BMP7 as an oncogene in hepatocellular carcinoma. |
| Q42545218 | Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation |
| Q35801340 | Protective Effect of Triptolide against Glomerular Mesangial Cell Proliferation and Glomerular Fibrosis in Rats Involves the TGF- β 1/Smad Signaling Pathway |
| Q38010662 | Protein interaction networks in medicine and disease |
| Q47099863 | Proteotoxic Stress Desensitizes TGF-beta Signaling Through Receptor Downregulation in Retinal Pigment Epithelial Cells |
| Q35732584 | Pulmonary arterial hypertension: advances in pathophysiology and management |
| Q39700863 | Quantifying the Relative Importance of Phylogeny and Environmental Preferences As Drivers of Gene Content in Prokaryotic Microorganisms. |
| Q39507533 | Quantitative phosphoproteomics of transforming growth factor-β signaling in colon cancer cells. |
| Q39887458 | RETRACTED: Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3. |
| Q35585587 | RNA sequencing identifies upregulated kyphoscoliosis peptidase and phosphatidic acid signaling pathways in muscle hypertrophy generated by transgenic expression of myostatin propeptide |
| Q30275433 | Reactive Oxygen Species/Nitric Oxide Mediated Inter-Organ Communication in Skeletal Muscle Wasting Diseases |
| Q46191291 | Rebamipide inhibits gastric cancer cell growth |
| Q58725014 | Recent Topics in Fibrodysplasia Ossificans Progressiva |
| Q40003255 | Recombinant N-Terminal Slit2 Inhibits TGF-β-Induced Fibroblast Activation and Renal Fibrosis |
| Q40680736 | Reconstitution of Smad3 restores TGF-beta response of tissue inhibitor of metalloprotease-1 upregulation in human choriocarcinoma cells |
| Q34599321 | Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints |
| Q35652597 | Regulation of Smad activities |
| Q24675955 | Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars |
| Q35691559 | Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation |
| Q38948512 | Regulatory T Cells and Cancer: A Two-Sided Story |
| Q39872463 | Regulatory expression of genes related to metastasis by TGF-beta and activin A in B16 murine melanoma cells. |
| Q35562396 | Relative expression of genes encoding SMAD signal transduction factors in human granulosa cells is correlated with oocyte quality |
| Q48601400 | Relative mRNA expression and immunolocalization for transforming growth factor-beta (TGF-β) and their effect on in vitro development of caprine preantral follicles. |
| Q28246633 | Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1 |
| Q24534996 | Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells |
| Q80125616 | Requirement for the dynein light chain km23-1 in a Smad2-dependent transforming growth factor-beta signaling pathway |
| Q35735095 | Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functions. |
| Q52552384 | Restoration of an impaired TGF-beta1 autocrine growth-inhibitory circuit results in growth inhibition of ovarian epithelial cancer cells and complete inhibition of their tumorigenicity. |
| Q44645815 | Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner. |
| Q33651188 | Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells |
| Q33913063 | RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species |
| Q58803267 | Role of Cytokine Combinations on CD4+ T Cell Differentiation, Partial Polarization, and Plasticity: Continuous Network Modeling Approach |
| Q44755593 | Role of IL-15 in the modulation of TGF-β1-mediated inflammation in asthma |
| Q42801627 | Role of IL-17 and TGF-β in peritoneal adhesion formation after surgical trauma |
| Q40110631 | Role of RGM coreceptors in bone morphogenetic protein signaling |
| Q89805308 | Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases |
| Q47096314 | Role of Transforming Growth Factor β in Uterine Fibroid Biology |
| Q34623130 | Role of transforming growth factor Beta in corneal function, biology and pathology |
| Q36399296 | Role of transforming growth factor-beta in hematologic malignancies |
| Q58556295 | Roles of Smads Family and Alternative Splicing Variants of Smad4 in Different Cancers |
| Q35703376 | Roles of cell-extrinsic growth factors in vertebrate eye pattern formation and retinogenesis |
| Q38969658 | SHON, a novel secreted protein, regulates epithelial-mesenchymal transition through transforming growth factor-β signaling in human breast cancer cells |
| Q55261894 | SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma. |
| Q28572073 | SMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cells |
| Q35199407 | SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise |
| Q58802831 | STAT3 in Skeletal Muscle Function and Disorders |
| Q28594857 | Sertad1 encodes a novel transcriptional co-activator of SMAD1 in mouse embryonic hearts |
| Q34439502 | Serum starvation regulates E-cadherin upregulation via activation of c-Src in non-small-cell lung cancer A549 cells |
| Q35191429 | Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway |
| Q41544383 | Signal integration in TGF-β, WNT, and Hippo pathways |
| Q38148526 | Signaling by the TGFβ superfamily |
| Q50788157 | Simulated microgravity promoted differentiation of bipotential murine oval liver stem cells by modulating BMP4/Notch1 signaling. |
| Q33312416 | Sizn1 is a novel protein that functions as a transcriptional coactivator of bone morphogenic protein signaling |
| Q99565624 | Sja-miR-71a in Schistosome egg-derived extracellular vesicles suppresses liver fibrosis caused by schistosomiasis via targeting semaphorin 4D |
| Q35118772 | Sliding doors: clathrin-coated pits or caveolae? |
| Q28585087 | Smad expression during kidney development |
| Q24307319 | Smad inhibition by the Ste20 kinase Misshapen |
| Q34599300 | Smad signalling in the ovary |
| Q28506361 | Smad1 and Smad8 function similarly in mammalian central nervous system development. |
| Q28589411 | Smad2 and Smad3 coordinately regulate craniofacial and endodermal development |
| Q36610935 | Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification |
| Q40729185 | Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma |
| Q35672543 | Smad3-dependent signaling underlies the TGF-β1-mediated enhancement in astrocytic iNOS expression |
| Q39261745 | Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells |
| Q41624899 | Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis |
| Q44507331 | Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats |
| Q36982849 | Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2. |
| Q35591035 | Smurf1 facilitates myogenic differentiation and antagonizes the bone morphogenetic protein-2-induced osteoblast conversion by targeting Smad5 for degradation |
| Q37180614 | SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis |
| Q37498907 | SnoN in regulation of embryonic development and tissue morphogenesis |
| Q27642513 | Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly of the Large Latent Complex that Sequesters Latent TGF-β |
| Q33581581 | Specific microRNA-mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein-Related Peptidase 6. |
| Q60919827 | Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells |
| Q38456489 | Strategies for improving the physiological relevance of human engineered tissues. |
| Q27674793 | Structural basis for specificity of TGFβ family receptor small molecule inhibitors |
| Q34196017 | Sumoylation of Smad4, the Common Smad Mediator of Transforming Growth Factor-β Family Signaling |
| Q91410022 | Suppression of miR-143-3p contributes to the anti-fibrosis effect of atorvastatin on myocardial tissues via the modulation of Smad2 activity |
| Q28118751 | Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization |
| Q39418554 | Synthesis of embryonic tendon-like tissue by human marrow stromal/mesenchymal stem cells requires a three-dimensional environment and transforming growth factor β3. |
| Q37094346 | Systemic administration of follistatin288 increases muscle mass and reduces fat accumulation in mice |
| Q24812641 | Systems biology approaches in cell signaling research |
| Q24323998 | TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal |
| Q33809976 | TGF- β: an important mediator of allergic disease and a molecule with dual activity in cancer development |
| Q45916809 | TGF-beta 1/Smads signaling stimulates renal interstitial fibrosis in experimental AAN. |
| Q28508328 | TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA |
| Q39967368 | TGF-beta coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival. |
| Q37583926 | TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence |
| Q43062779 | TGF-beta receptors, in a Smad-independent manner, are required for terminal skeletal muscle differentiation |
| Q40666886 | TGF-beta/Smad signaling inhibits IFN-gamma and TNF-alpha-induced TARC (CCL17) production in HaCaT cells |
| Q40599887 | TGF-beta1 (transforming growth factor-beta1)-mediated adhesion of gastric carcinoma cells involves a decrease in Ras/ERKs (extracellular-signal-regulated kinases) cascade activity dependent on c-Src activity |
| Q37307155 | TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation |
| Q40607992 | TGF-beta1-promoted epithelial-to-mesenchymal transformation and cell adhesion contribute to TGF-beta1-enhanced cell migration in SMMC-7721 cells |
| Q36868060 | TGF-β Signaling Regulates Pancreatic β-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression |
| Q36019721 | TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis |
| Q36458347 | TGF-β in tolerance, development and regulation of immunity |
| Q29036999 | TGF-β signaling in T cells: roles in lymphoid and epithelial neoplasia |
| Q26851198 | TGF-β/Smad signaling in renal fibrosis |
| Q37678740 | TGF-β1 induces EMT reprogramming of porcine bladder urothelial cells into collagen producing fibroblasts-like cells in a Smad2/Smad3-dependent manner |
| Q45825684 | TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice |
| Q41280741 | TGFbeta-induced RhoA activation and fibronectin production in mesangial cells require caveolae |
| Q45095156 | TGFbeta-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation |
| Q34545421 | TGFbeta/BMP inhibits the bone marrow transformation capability of Hoxa9 by repressing its DNA-binding ability |
| Q34121672 | TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells |
| Q39653885 | TGFβ and EGF synergistically induce a more invasive phenotype of epithelial ovarian cancer cells |
| Q36720507 | TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation |
| Q35057074 | TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment |
| Q28975741 | TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion |
| Q38976764 | TNF-α enhances the effect of TGF-β on Gli2 expression in the KG-1 leukemic cell line |
| Q41496876 | TSP-1 in lung fibrosis |
| Q37769804 | Targeting inflammatory pathways for tumor radiosensitization. |
| Q90242473 | Targeting metabolic dysregulation for fibrosis therapy |
| Q64062269 | The Activin Receptor, Activin-Like Kinase 4, Mediates Activation of Hypoxia Inducible Factor-1 |
| Q95822037 | The Alterations of IL-1Beta, IL-6, and TGF-Beta Levels in Hippocampal CA3 Region of Chronic Restraint Stress Rats after Electroacupuncture (EA) Pretreatment |
| Q35163113 | The BglF sensor recruits the BglG transcription regulator to the membrane and releases it on stimulation |
| Q46648766 | The Drosophila type II receptor, Wishful thinking, binds BMP and myoglianin to activate multiple TGFbeta family signaling pathways |
| Q38009603 | The Mix family of homeobox genes--key regulators of mesendoderm formation during vertebrate development. |
| Q36473791 | The Prodomain-Containing BMP9 Produced from a Stable Line Effectively Regulates the Differentiation of Mesenchymal Stem Cells |
| Q24651192 | The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase |
| Q35553694 | The TGF-β Superfamily and Its Roles in the Human Ovary and Placenta |
| Q40996773 | The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells |
| Q33474830 | The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation |
| Q57071538 | The activation of microRNA-520h-associated TGF-β1/c-Myb/Smad7 axis promotes epithelial ovarian cancer progression |
| Q48016320 | The acute respiratory distress syndrome: a role for transforming growth factor-beta 1. |
| Q26786137 | The balance of powers: Redox regulation of fibrogenic pathways in kidney injury |
| Q35088148 | The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology |
| Q36241235 | The disparate role of BMP in stem cell biology |
| Q38917538 | The effects of WW2/WW3 domains of Smurf2 molecule on TGF-β signaling and arginase I gene expression. |
| Q53950325 | The effects of functional polymorphisms in the TGFβ1 gene on nasopharyngeal carcinoma susceptibility. |
| Q36698998 | The effects of ingested mammalian blood factors on vector arthropod immunity and physiology |
| Q33898256 | The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |
| Q34049736 | The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3. |
| Q39862772 | The extracellular domain of the TGFbeta type II receptor regulates membrane raft partitioning. |
| Q37403100 | The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization |
| Q43136778 | The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone |
| Q24337892 | The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines |
| Q28506894 | The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation |
| Q62583448 | The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes |
| Q26772167 | The pituitary TGFβ1 system as a novel target for the treatment of resistant prolactinomas |
| Q43219957 | The predictive value of genes of the TGF-beta1 pathway in multimodally treated squamous cell carcinoma of the esophagus. |
| Q44984281 | The prognostic value of Smad4 mRNA in patients with prostate cancer |
| Q34012685 | The pursuit of ES cell lines of domesticated ungulates |
| Q38302662 | The retinoblastoma protein is an essential mediator of osteogenesis that links the p204 protein to the Cbfa1 transcription factor thereby increasing its activity. |
| Q35782195 | The role of Fas ligand and transforming growth factor beta in tumor progression: molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy |
| Q37958629 | The role of TGF-β in the pathogenesis of primary open-angle glaucoma. |
| Q52688883 | The role of TGF-β/SMAD4 signaling in cancer. |
| Q29040166 | The role of angiogenic factors in fibroid pathogenesis: potential implications for future therapy |
| Q57180571 | The role of cellular contact and TGF-beta signaling in the activation of the epithelial mesenchymal transition (EMT) |
| Q35643525 | The role of epithelial-to-mesenchymal transition in renal fibrosis |
| Q39277178 | The roles of transforming growth factor-β1 and vascular endothelial growth factor in the tracheal granulation formation |
| Q33929804 | The self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation |
| Q40462575 | The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP. |
| Q39262611 | The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid-imidazolide alters transforming growth factor beta-dependent signaling and cell migration by affecting the cytoskeleton and the polarity complex |
| Q51568474 | The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways. |
| Q96301555 | Therapeutic Effects of Focused Ultrasound on Expression of Notch1, C-Fos and Transforming Growth Factor-β3 in Vulvar Skin of SD Rats with Vulvar Lichen Simplex Chronicus |
| Q33674615 | Therapeutic Implications of PPARgamma in Human Osteosarcoma |
| Q39171149 | Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma |
| Q34441994 | Time course, distribution and cell types of induction of transforming growth factor betas following middle cerebral artery occlusion in the rat brain |
| Q34661707 | Tissue repair: The hidden drama |
| Q57092293 | Tissue, cell and stage specificity of (epi)mutations in cancers |
| Q64249105 | Trabecular meshwork cells are a valuable resource for cellular therapy of glaucoma |
| Q39745931 | Transcription factor IIB (TFIIB)-related protein (pBrp), a plant-specific member of the TFIIB-related protein family. |
| Q89640757 | Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins (BMPs) in lineage commitment and differentiation of mesenchymal stem cells (MSCs) |
| Q58773672 | Transforming Growth Factor Beta Signaling in Dendritic Cells Is Required for Immunotolerance to Sperm in the Epididymis |
| Q28083526 | Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression |
| Q38794443 | Transforming growth factor (TGF) β1 acted through miR-130b to increase integrin α5 to promote migration of colorectal cancer cells |
| Q39185363 | Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD- and p38 MAPK-dependent mechanism in skeletal muscle. |
| Q36685205 | Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy |
| Q30430202 | Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function |
| Q26824939 | Transforming growth factor β signaling in uterine development and function |
| Q33779562 | Transforming growth factor β1 promotes invasion of human JEG-3 trophoblast cells via TGF-β/Smad3 signaling pathway |
| Q35172753 | Transforming growth factor-beta and its role in asthma |
| Q26996742 | Transforming growth factor-beta and matrix metalloproteinases: functional interactions in tumor stroma-infiltrating myeloid cells |
| Q42772810 | Transforming growth factor-beta gene expression studies in nasal mucosal biopsies in naturally occurring allergic rhinitis |
| Q42948406 | Transforming growth factor-beta inhibits aromatase gene transcription in human trophoblast cells via the Smad2 signaling pathway |
| Q34992779 | Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesis |
| Q35217394 | Transforming growth factor-beta signaling in normal and malignant hematopoiesis |
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