scholarly article | Q13442814 |
P50 | author | Krishnaraj Rajalingam | Q87655285 |
Lisa J Crawford | Q96303458 | ||
Roisin M McAvera | Q96303460 | ||
P2093 | author name string | Dharminder Chauhan | |
Andrew D Chantry | |||
Alexandra E Irvine | |||
David C Campbell | |||
Michelle A Lawson | |||
Aswini Krishnan | |||
Claudia Hamilton | |||
Jennifer M Down | |||
Jonathan J Morgan | |||
Treen C Morris | |||
P2860 | cites work | The Influence of Metabolism on Drug Response in Cancer | Q59136910 |
Carfilzomib for relapsed and refractory multiple myeloma | Q64083853 | ||
CD38 in Adenosinergic Pathways and Metabolic Re-programming in Human Multiple Myeloma Cells: In-tandem Insights From Basic Science to Therapy | Q64093247 | ||
Targeting MYC in multiple myeloma | Q87842402 | ||
Ubiquitination: Friend and foe in cancer | Q88976865 | ||
HUWE1 controls the development of non-small cell lung cancer through down-regulation of p53 | Q90352927 | ||
Bortezomib and other proteosome inhibitors-induced peripheral neurotoxicity: From pathogenesis to treatment | Q90919275 | ||
Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells | Q92128904 | ||
Multiple myeloma: Every year a new standard? | Q92675436 | ||
Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion | Q92761067 | ||
Ixazomib for the treatment of multiple myeloma | Q93028409 | ||
The power of proteasome inhibition in multiple myeloma | Q93067519 | ||
Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas | Q94452068 | ||
A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities | Q27658641 | ||
The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation | Q28280330 | ||
Homeostatic defects in B cells deficient in the E3 ubiquitin ligase ARF-BP1 are restored by enhanced expression of MYC | Q33828914 | ||
HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold | Q34298040 | ||
HUWE1 and TRIP12 collaborate in degradation of ubiquitin-fusion proteins and misframed ubiquitin | Q34500475 | ||
NOD/SCID-GAMMA mice are an ideal strain to assess the efficacy of therapeutic agents used in the treatment of myeloma bone disease | Q35175289 | ||
Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase | Q35275756 | ||
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. | Q35679564 | ||
Characterization of ARF-BP1/HUWE1 interactions with CTCF, MYC, ARF and p53 in MYC-driven B cell neoplasms | Q36057221 | ||
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance | Q36338365 | ||
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 | Q36902911 | ||
HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation | Q37618001 | ||
Blockade of deubiquitylating enzyme Rpn11 triggers apoptosis in multiple myeloma cells and overcomes bortezomib resistance | Q38743857 | ||
HUWE1 interacts with PCNA to alleviate replication stress | Q38773179 | ||
The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice. | Q38798189 | ||
The Role of c-MYC in B-Cell Lymphomas: Diagnostic and Molecular Aspects | Q39221506 | ||
Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma | Q41971182 | ||
HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion | Q42101475 | ||
Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis | Q42261427 | ||
A conformational switch regulates the ubiquitin ligase HUWE1. | Q42321543 | ||
Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling | Q42377050 | ||
Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation. | Q45925019 | ||
Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability | Q47093588 | ||
QuPath: Open source software for digital pathology image analysis | Q47108040 | ||
E3 ubiquitin ligases in cancer and implications for therapies | Q47636038 | ||
HUWE1 variants cause dominant X-linked intellectual disability: a clinical study of 21 patients. | Q48227714 | ||
The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling | Q48964297 | ||
Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-H19 Cascade. | Q50902450 | ||
Resistance to proteasome inhibitors and other targeted therapies in myeloma. | Q53693372 | ||
Metabolic Features of Multiple Myeloma. | Q53694850 | ||
Role of Proteasome Inhibitors in Relapsed and/or Refractory Multiple Myeloma | Q57117709 | ||
Ubiquitination by HUWE1 in tumorigenesis and beyond | Q57161316 | ||
Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor | Q57964092 | ||
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma | Q58792995 | ||
P577 | publication date | 2020-06-10 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma |
Q98195879 | Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia | cites work | P2860 |