scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1020232019 |
P356 | DOI | 10.1038/NG0594-85 |
P698 | PubMed publication ID | 7915601 |
P5875 | ResearchGate publication ID | 31934300 |
P2093 | author name string | Li H | |
Chen F | |||
Duh FM | |||
Latif F | |||
Tory K | |||
Liu S | |||
Schmidt L | |||
Gnarra JR | |||
Weng Y | |||
Wei MH | |||
P2860 | cites work | Mutations of the RET proto-oncogene in Hirschsprung's disease | Q24324643 |
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma | Q55670928 | ||
Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC | Q57591365 | ||
Clinical and genetic studies of renal cell carcinomas in a family with a constitutional chromosome 3;8 translocation. Genetics of familial renal carcinoma | Q70520141 | ||
Loss of heterozygosity on the short arm of chromosome 3 in mesothelioma cell lines and solid tumors | Q71666500 | ||
The results of radical nephrectomy for renal cell carcinoma | Q72340879 | ||
Identification of the von Hippel-Lindau disease tumor suppressor gene | Q29618644 | ||
Von Hippel-Lindau disease: a genetic study | Q33597245 | ||
Cytogenetic and molecular genetic studies of follicular and papillary thyroid cancers | Q34209006 | ||
Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease | Q34336251 | ||
von Hippel-Lindau disease affecting 43 members of a single kindred | Q38596547 | ||
Hereditary papillary renal cell carcinoma | Q40814773 | ||
Cytogenetics of papillary renal cell tumors | Q41676155 | ||
Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation | Q41751694 | ||
Establishment and characterization of a cell line (SS78) from a human renal cell carcinoma | Q42801958 | ||
Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. | Q48114164 | ||
Human renal carcinoma: characterization of five new cell lines. | Q53437651 | ||
Tumor suppressor gene allelic loss in human renal cancers. | Q53477783 | ||
P4510 | describes a project that uses | SK-RC-62 | Q54954637 |
SK-RC-8 | Q54954641 | ||
SK-RC-9 | Q54954642 | ||
SS78 | Q54955686 | ||
UM-RC-11 | Q54990782 | ||
UM-RC-2 | Q54990783 | ||
UM-RC-3 | Q54990784 | ||
UM-RC-5 | Q54990785 | ||
UM-RC-6 | Q54990787 | ||
UM-RC-7 | Q54990788 | ||
UOK101 | Q54991268 | ||
UOK102 | Q54991269 | ||
UOK110 | Q54991282 | ||
UOK111 | Q54991285 | ||
UOK115 | Q54991318 | ||
UOK117 | Q54991322 | ||
UOK118 | Q54991328 | ||
UOK123 | Q54991342 | ||
UOK130 | Q54991357 | ||
UOK135 | Q54991365 | ||
UOK139 | Q54991370 | ||
UOK140 | Q54991371 | ||
UOK141 | Q54991373 | ||
UOK142 | Q54991375 | ||
UOK150 | Q54991380 | ||
UOK151 | Q54991381 | ||
UOK154 | Q54991384 | ||
UOK161 | Q54991407 | ||
UOK162 | Q54991408 | ||
UOK163 | Q54991409 | ||
UOK164 | Q54991410 | ||
786-O | Q54604950 | ||
A-498 | Q54606041 | ||
KTCTL-13 | Q54900630 | ||
KTCTL-140 | Q54900633 | ||
KTCTL-2 | Q54900639 | ||
KTCTL-26A | Q54900643 | ||
KTCTL-53 | Q54900650 | ||
SK-RC-28 | Q54954564 | ||
SK-RC-48 | Q54954595 | ||
SK-RC-61 | Q54954614 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell line | Q21014462 |
P304 | page(s) | 85-90 | |
P577 | publication date | 1994-05-01 | |
P1433 | published in | Nature Genetics | Q976454 |
P1476 | title | Mutations of the VHL tumour suppressor gene in renal carcinoma | |
P478 | volume | 7 |
Q54604950 | 786-O |
Q54606041 | A-498 |
Q54900630 | KTCTL-13 |
Q54900633 | KTCTL-140 |
Q54900639 | KTCTL-2 |
Q54900643 | KTCTL-26A |
Q54900650 | KTCTL-53 |
Q54954564 | SK-RC-28 |
Q54954595 | SK-RC-48 |
Q54954614 | SK-RC-61 |
Q54954637 | SK-RC-62 |
Q54954641 | SK-RC-8 |
Q54954642 | SK-RC-9 |
Q54955686 | SS78 |
Q54990782 | UM-RC-11 |
Q54990783 | UM-RC-2 |
Q54990784 | UM-RC-3 |
Q54990785 | UM-RC-5 |
Q54990787 | UM-RC-6 |
Q54990788 | UM-RC-7 |
Q54991268 | UOK101 |
Q54991269 | UOK102 |
Q54991282 | UOK110 |
Q54991285 | UOK111 |
Q54991318 | UOK115 |
Q54991322 | UOK117 |
Q54991328 | UOK118 |
Q54991342 | UOK123 |
Q54991357 | UOK130 |
Q54991365 | UOK135 |
Q54991370 | UOK139 |
Q54991371 | UOK140 |
Q54991373 | UOK141 |
Q54991375 | UOK142 |
Q54991380 | UOK150 |
Q54991381 | UOK151 |
Q54991384 | UOK154 |
Q54991407 | UOK161 |
Q54991408 | UOK162 |
Q54991409 | UOK163 |
Q54991410 | UOK164 |
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Q80324391 | Cytogenetic alterations in renal tumors: a study of 38 Southeast Asian patients |
Q55670950 | Cytogenetic and molecular analysis of early stage renal cell carcinomas in a family with a translocation (2;3)(q35;q21) |
Q70822994 | Cytogenetic characterization of a familial papillary renal cell carcinoma |
Q77508304 | Cytologic analysis of papillary renal cell carcinoma |
Q44192570 | DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras. |
Q74449047 | Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma |
Q91341105 | Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers |
Q39178416 | Degrons in cancer |
Q89719539 | Deletion of Von Hippel-Lindau Interferes with Hyper Osmolality Induced Gene Expression and Induces an Unfavorable Gene Expression Pattern |
Q38022052 | Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity |
Q39019458 | Deregulated expression of VHL mRNA variants in papillary thyroid cancer. |
Q84210212 | Description of 2 angiogenic phenotypes in clear cell renal cell carcinoma |
Q27333673 | Design and analysis of a Petri net model of the Von Hippel-Lindau (VHL) tumor suppressor interaction network |
Q73799794 | Detailed microsatellite analysis of chromosome 3p region in non-papillary renal cell carcinomas |
Q38715906 | Detecting circulating tumor DNA in renal cancer: An open challenge. |
Q57631389 | Detection of a germline mutation and somatic homozygous loss of the von Hippel-Lindau tumor-suppressor gene in a family with a de novo mutation |
Q73187074 | Detection of a novel germline mutation in the von Hippel-Lindau tumour-suppressor gene by fluorescence-labelled base excision sequence scanning (F-BESS) |
Q73555871 | Detection of gene deletion in single metastatic tumour cells in lymphnode tissue by fluorescent in-situ hybridisation |
Q38461457 | Detection of loss of heterozygosity at chromosome 3p25-26 in primary and metastatic ovarian clear-cell carcinoma: utilization of microdissection and polymerase chain reaction in archival tissues |
Q33573577 | Determination of angptl4 mRNA as a diagnostic marker of primary and metastatic clear cell renal-cell carcinoma |
Q36643235 | Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma |
Q82142251 | Determination of vhl gene mutations in sporadic renal cell carcinoma |
Q53430411 | Development of high-grade renal cell carcinomas in rats independently of somatic mutations in the Tsc2 and VHL tumor suppressor genes. |
Q40407399 | Diagnosis and prognosis of renal-cell tumors: a molecular approach |
Q40535795 | Diagnosis and the new genetics |
Q73223860 | Diagnosis of renal cancer by molecular urinalysis |
Q33481999 | Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes |
Q40535916 | Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney |
Q52880866 | Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C-MYC axis under hypoxia. |
Q58323654 | Direct Interaction of the β-Domain of VHL Tumor Suppressor Protein with the Regulatory Domain of Atypical PKC Isotypes |
Q52061865 | Distance-based reconstruction of tree models for oncogenesis. |
Q34323668 | Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity |
Q34132481 | Dna adducts, mutations, and cancer 2000. |
Q37799821 | Does axitinib (AG-01376) have a future role in metastatic renal cell carcinoma and other malignancies? |
Q36916355 | Down-regulation of C12orf59 is associated with a poor prognosis and VHL mutations in renal cell carcinoma |
Q24644903 | Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes |
Q40645070 | Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells |
Q35899912 | Downregulation of dystroglycan glycosyltransferases LARGE2 and ISPD associate with increased mortality in clear cell renal cell carcinoma. |
Q39490219 | Downregulation of fumarate hydratase is related to tumorigenesis in sporadic renal cell cancer. |
Q38737865 | Drug Development Against Metastatic Cancers |
Q28086796 | Dysregulation of ubiquitin ligases in cancer |
Q34707583 | Early identification of patients with von Hippel-Lindau disease at risk for pheochromocytoma |
Q59571893 | Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma |
Q52618590 | Effects of point mutations in pVHL on the binding of HIF-1α. |
Q43276017 | Efficacy and safety of sorafenib in patients with advanced renal cell carcinoma with and without prior cytokine therapy, a subanalysis of TARGET. |
Q35022463 | Elevated estrogen receptor-α in VHL-deficient condition induces microtubule organizing center amplification via disruption of BRCA1/Rad51 interaction |
Q47855049 | Elevated serum levels of cardiovascular biomarkers are associated with progression of renal cancer |
Q24336681 | Elongin (SIII): A Multisubunit Regulator of Elongation by RNA Polymerase II |
Q36421535 | Elucidation of the molecular signatures of renal cell carcinoma by gene expression profiling |
Q36302842 | Emerging drugs for renal cell carcinoma |
Q84159104 | Emerging drugs for renal cell carcinoma |
Q38815893 | Emerging growth factor receptor antagonists for the treatment of renal cell carcinoma |
Q26862957 | Emerging role for novel immunotherapy agents in metastatic renal cell carcinoma: from bench to bedside |
Q38176255 | Emerging roles of miR-210 and other non-coding RNAs in the hypoxic response |
Q81117362 | Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): report of two cases with analysis of the VHL gene |
Q50435582 | Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): sine qua non radiology-pathology and the University of Texas MD Anderson Cancer Center experience |
Q47911795 | Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression |
Q73623166 | Endoplasmic reticulum/cytosolic localization of von Hippel-Lindau gene products is mediated by a 64-amino acid region |
Q57608167 | Epididymal cystadenomas and epithelial tumourlets: effects of VHL deficiency on the human epididymis |
Q36518228 | Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. |
Q34182910 | Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers. |
Q40352903 | Epigenetic inactivation of the candidate tumor suppressor gene HOXB13 in human renal cell carcinoma |
Q88985337 | Epigenetics in renal cell cancer: mechanisms and clinical applications |
Q41574276 | Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma |
Q40908590 | Establishment and characterization of seven human renal cell carcinoma cell lines |
Q78139556 | Establishment of experimental conditions for the rapid detection of mutations in the von Hippel-Lindau gene by parallel temperature gradient gel electrophoresis |
Q97428885 | Etiologic heterogeneity of clear-cell and papillary renal cell carcinoma in the Netherlands Cohort Study |
Q92382571 | Evaluation of immunotherapy and targeted therapy treatment on renal cell carcinoma: A Bayesian network analysis |
Q53583449 | Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110. |
Q35787295 | Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization |
Q41108912 | Evaluation of tyrosine kinase receptors in brain metastases of clear cell renal cell carcinoma reveals cMet as a negative prognostic factor |
Q34417931 | Everolimus - a new approach in the treatment of renal cell carcinoma |
Q38997782 | Evidence for aldosterone-dependent growth of renal cell carcinoma |
Q80552108 | Evidence of graft-versus-tumour effect following allogeneic haematopoietic stem cell transplantation in renal cancer other than clear cell type |
Q57608170 | Evolution of VHL tumourigenesis in nerve root tissue |
Q38676794 | Evolving Treatment Paradigm in Metastatic Renal Cell Carcinoma |
Q35674241 | Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma. |
Q60445178 | Expression of CXCR3 on Mononuclear Cells and CXCR3 Ligands in Patients With Metastatic Renal Cell Carcinoma in Response to Systemic IL-2 Therapy |
Q53668779 | Expression of HGF/SF and Met protein is associated with genetic alterations of VHL gene in primary renal cell carcinomas. |
Q73467027 | Expression of HIF-1 and ubiquitin in conventional renal cell carcinoma: relationship to mutations of the von Hippel-Lindau tumor suppressor gene |
Q50178478 | Expression of VHL and HIF-1α and Their Clinicopathologic Significance in Benign and Malignant Lesions of the Gallbladder |
Q80357056 | Expression of fibronectin and HIF-1alpha in renal cell carcinomas: relationship to von Hippel-Lindau gene inactivation |
Q38491062 | Expression of hypoxia inducible factor-1α and 2α in conventional renal cell carcinoma with or without sarcomatoid differentiation |
Q45134199 | Expression of insulin-like growth factor I receptor and survival in patients with clear cell renal cell carcinoma |
Q41328849 | Expression of nm23 in cell lines derived from patients with metastatic renal cell carcinoma |
Q36437594 | Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis |
Q24300575 | Expression of the ammonia transporter, rh C glycoprotein, in normal and neoplastic human kidney |
Q43110710 | Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer. |
Q35842166 | Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers |
Q57660049 | Extraneural Hemangioblastoma |
Q26800869 | Extraneural hemangioblastoma of the kidney: the challenge for clinicopathological diagnosis |
Q49496028 | Extraneuraxial Hemangioblastoma: Clinicopathologic Features and Review of the Literature |
Q45980708 | FOXO1 and TCF7L2 genes involved in metastasis and poor prognosis in clear cell renal cell carcinoma. |
Q34515955 | Familial adult renal neoplasia |
Q35434654 | Familial clear cell renal cell carcinoma (FCRC): clinical features and mutation analysis of the VHL, MET, and CUL2 candidate genes |
Q35687676 | Familial renal cancer: molecular genetics and surgical management |
Q40410169 | Familial renal cell carcinoma: review of recent molecular genetics |
Q78582609 | Familial risk of cancer by site and histopathology |
Q39798868 | Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma. |
Q38175454 | Fibroblast growth factor receptors as therapeutic targets in clear-cell renal cell carcinoma. |
Q73467010 | Five new cases of juvenile renal cell carcinoma with translocations involving Xp11.2: a cytogenetic and morphologic study |
Q38414604 | Fluorescent In-situ Hybridization Study of Non-papillary Oncocytic/Eosinophilic Renal Cell Carcinoma |
Q35893624 | Focus on kidney cancer |
Q33886538 | Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC. |
Q46006357 | Fragile histidine triad (FHIT) gene and its association with p53 protein expression in the progression of gall bladder cancer. |
Q58006216 | Frequency of Von Hippel-Lindau germline mutations in classic and non-classic Von Hippel-Lindau disease identified by DNA sequencing, Southern blot analysis and multiplex ligation-dependent probe amplification |
Q37275151 | Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species. |
Q35706831 | Functional Subunits of Eukaryotic Chaperonin CCT/TRiC in Protein Folding |
Q36648074 | Functional evaluation of the apoptosome in renal cell carcinoma |
Q73784996 | Functioning thoracic paraganglioma: association with Von Hippel-Lindau syndrome |
Q81342868 | Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma |
Q53847052 | Gene expression of GLUT isoforms and VHL in oral squamous cell carcinoma. |
Q53612481 | Gene expression profiling of renal cell carcinoma: a DNA macroarray analysis. |
Q24814730 | Gene expression profiling predicts survival in conventional renal cell carcinoma |
Q35920812 | Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells |
Q52590924 | Generation of autochthonous mouse models of clear cell renal cell carcinoma: mouse models of renal cell carcinoma. |
Q36028393 | Generation of loss of heterozygosity and its dependency on p53 status in human lymphoblastoid cells |
Q98200998 | Genetic Alterations in Renal Cancers: Identification of The Mechanisms Underlying Cancer Initiation and Progression and of Therapeutic Targets |
Q40972502 | Genetic alterations in breast cancer. |
Q74812391 | Genetic analysis of 2 cases of clear cell renal cancer in 2 sisters |
Q71048260 | Genetic analysis of synchronous mucinous tumors of the ovary and appendix |
Q51965383 | Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis. |
Q52856655 | Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer. |
Q40718800 | Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter |
Q81267790 | Genetic basis for kidney cancer: opportunity for disease-specific approaches to therapy |
Q36794767 | Genetic basis of kidney cancer: a model for developing molecular-targeted therapies |
Q36354841 | Genetic basis of kidney cancer: role of genomics for the development of disease-based therapeutics |
Q71343783 | Genetic changes in the origin and development of renal cell carcinoma (RCC) |
Q35064232 | Genetic disorders and renal cell carcinoma. |
Q80183290 | Genetic evaluation of von Hippel-Lindau disease for early diagnosis and improved prognosis |
Q74128948 | Genetic identification of bilateral primary or metastatic nonpapillary renal cell carcinoma |
Q57608157 | Genetic insights into the hypoxia-inducible factor (HIF) pathway |
Q39023793 | Genetic predisposition to kidney cancer |
Q34291328 | Genetic testing by cancer site: urinary tract |
Q37054515 | Genetics and epigenetics of renal cell cancer |
Q35838967 | Genome-wide mapping of Hif-1α binding sites in zebrafish |
Q37401031 | Genome-wide profiling of chromosomal alterations in renal cell carcinoma using high-density single nucleotide polymorphism arrays |
Q33947929 | Genomic Analysis as the First Step toward Personalized Treatment in Renal Cell Carcinoma |
Q35646364 | Genomic alterations in renal tumours: what have we learned in the era of comparative genomic hybridisation? |
Q36646352 | Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma |
Q96610153 | Genomic profiling in renal cell carcinoma |
Q46635938 | Genomic profiling of the genes on chromosome 3p in sporadic clear cell renal cell carcinoma |
Q90899773 | Genomics and clinical correlates of renal cell carcinoma |
Q38023071 | Genomics and epigenomics of renal cell carcinoma. |
Q33677726 | Genotype-phenotype correlation in von Hippel-Lindau disease: identification of a mutation associated with VHL type 2A |
Q44230145 | Genotype-phenotype correlation in von Hippel-Lindau families with renal lesions. |
Q74817219 | Genotype-phenotype correlations in von Hippel-Lindau disease |
Q55312690 | Germ-line mutation analysis in patients with von Hippel-Lindau disease in Japan: an extended study of 77 families. |
Q35889809 | Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma. |
Q45345804 | Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas |
Q79354832 | Germline mutation of von Hippel-Lindau (VHL) gene 695 G>A (R161Q) in a patient with a peculiar phenotype with type 2C VHL syndrome |
Q58862079 | Germline mutations detected in the von Hippel-Lindau disease tumor suppressor gene by Southern blot and direct genomic DNA sequencing |
Q44847029 | Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype |
Q44847047 | Germline mutations in the von Hippel-Lindau gene in Italian patients. |
Q92564013 | Germline polymorphisms in the Von Hippel-Lindau and Hypoxia-inducible factor 1-alpha genes, gene-environment and gene-gene interactions and renal cell cancer |
Q55172634 | Global isoform-specific transcript alterations and deregulated networks in clear cell renal cell carcinoma. |
Q46961036 | Glucose transporter-1 expression in renal cell carcinoma and its correlation with hypoxia inducible factor-1 alpha |
Q51158842 | Gramicidin A: A New Mission for an Old Antibiotic. |
Q89830041 | Growth Rates of Genetically Defined Renal Tumors: Implications for Active Surveillance and Intervention |
Q44068443 | HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron |
Q36609852 | HIF and fumarate hydratase in renal cancer |
Q35086143 | HIF hydroxylation and the mammalian oxygen-sensing pathway |
Q29615945 | HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability |
Q38666170 | HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond |
Q35564188 | HIF-1: an oxygen response system with special relevance to the kidney |
Q35891283 | HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation |
Q38274783 | HIF1α expression under normoxia in prostate cancer--which pathways to target? |
Q92159808 | HOTAIRM1 lncRNA is downregulated in clear cell renal cell carcinoma and inhibits the hypoxia pathway |
Q36839571 | Harnessing synthetic lethal interactions in anticancer drug discovery |
Q35099516 | Heat shock protein 90 as a molecular target for cancer therapeutics |
Q36187025 | Heat-shock protein 90 inhibitors in antineoplastic therapy: is it all wrapped up? |
Q86443035 | Hemangioblastoma of the gastrointestinal tract: a first case |
Q42858934 | Hepatocyte growth factor-stimulated renal tubular mitogenesis: effects on expression of c-myc, c-fos, c-met, VEGF and the VHL tumour-suppressor and related genes |
Q35609575 | Hereditary kidney cancer |
Q37287088 | Hereditary kidney cancer: unique opportunity for disease-based therapy. |
Q34318458 | Hereditary papillary renal cell carcinoma: clinical studies in 10 families |
Q41046229 | High cell density induces vascular endothelial growth factor expression via protein tyrosine phosphorylation. |
Q74688598 | High expression levels of insulin-like growth factor-I receptor predict poor survival among women with clear-cell renal cell carcinomas |
Q59526211 | High incidence of renal tumours in vitamins A and E synthesis workers: A new cause of occupational cancer? |
Q30827424 | High telomerase activity correlates with the stabilities of genome and DNA ploidy in renal cell carcinoma |
Q81409194 | High-resolution analysis of DNA copy number alterations and gene expression in renal clear cell carcinoma |
Q35786795 | High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma |
Q35868041 | Highly penetrant hereditary cancer syndromes. |
Q38473548 | Histological subtyping and nuclear grading of renal cell carcinoma and their implications for survival: a retrospective nation-wide study of 629 patients |
Q39700386 | Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma. |
Q33735233 | Histopathology and molecular genetics of renal tumors toward unification of a classification system |
Q57209343 | Host immune response in renal cell cancer: Interleukin-4 (IL-4) and IL-10 mRNA are frequently detected in freshly collected tumor-infiltrating lymphocytes |
Q33765677 | Hypermethylation of tumor suppressor genes in cancer |
Q51962814 | Hypertension, antihypertensives and mutations in the Von Hippel-Lindau gene in renal cell carcinoma: results from the Netherlands Cohort Study. |
Q26863298 | HypoxamiRs and cancer: from biology to targeted therapy |
Q92918176 | Hypoxia and aging |
Q40213183 | Hypoxia and renal cell carcinoma: The influence of HIF1A+1772C/T functional genetic polymorphism on prognosis |
Q91129506 | Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI |
Q33543092 | Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification |
Q47887318 | Hypoxia inducible factor (HIF): its central role in renal cell cancer targeted therapy |
Q40356897 | Hypoxia requires notch signaling to maintain the undifferentiated cell state |
Q37234734 | Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer |
Q38938089 | Hypoxia-induced SUMOylation of E3 ligase HAF determines specific activation of HIF2 in clear-cell renal cell carcinoma. |
Q90837994 | Hypoxia-inducible factor 2α: a novel target in gliomas |
Q36857564 | Hypoxia-inducible factor-2alpha regulates the expression of TRAIL receptor DR5 in renal cancer cells |
Q26749159 | Hypoxic control of metastasis |
Q52645855 | Hypoxic marker CA IX and adhesion mediator β-catenin are downregulated by lymphocytic choriomeningitis virus persistent infection. |
Q42070258 | Hypoxic regulation of the noncoding genome and NEAT1. |
Q40232799 | IGF-I and IGFBP-3 augment transforming growth factor-beta actions in human renal carcinoma cells |
Q55043368 | Identification and characterization of Birt-Hogg-Dubé associated renal carcinoma. |
Q40415541 | Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31,500-element cDNA array |
Q92068655 | Identification of Four Pathological Stage-Relevant Genes in Association with Progression and Prognosis in Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis |
Q24634004 | Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma |
Q28203647 | Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor |
Q57384547 | Identification of a newVHLexon and complex splicing alterations in familial erythrocytosis or von Hippel-Lindau disease |
Q98623305 | Identification of anti-tumoral feedback loop between VHLα and hnRNPA2B1 in renal cancer |
Q38848220 | Identification of genes associated with renal cell carcinoma using gene expression profiling analysis |
Q24299968 | Identification of novel VHL target genes and relationship to hypoxic response pathways |
Q38304283 | Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling |
Q36718988 | Identification of somatic chromosomal abnormalities in hypothalamic hamartoma tissue at the GLI3 locus. |
Q39832009 | Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel-Lindau protein |
Q36718934 | Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics |
Q24654714 | Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex |
Q57695829 | Identifizierung VHL-assoziierter Veränderungen im klarzelligen Nierenzellkarzinom |
Q40286789 | Immune and genetic therapies for advanced renal cell carcinoma. |
Q34612711 | Immunoaffinity Enrichment and Liquid Chromatography-Selected Reaction Monitoring Mass Spectrometry for Quantitation of Carbonic Anhydrase 12 in Cultured Renal Carcinoma Cells |
Q73227598 | Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues |
Q35189579 | Impact of genetics on the diagnosis and treatment of renal cancer |
Q37780020 | Impact of the incorporation of tyrosine kinase inhibitor agents on the treatment of patients with a diagnosis of advanced renal cell carcinoma: study based on experience at the Hospital Universitario Central de Asturias. |
Q43282347 | Impairment of plasmacytoid dendritic cells for IFN production by the ligand for immunoglobulin-like transcript 7 expressed on human cancer cells |
Q51331802 | Implication of VHL, ERK5, and HIF-1alpha in clear cell renal cell carcinoma: Molecular basis. |
Q37069569 | Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors |
Q47934677 | In silico investigation of PHD-3 specific HIF1-α proline 567 hydroxylation: a new player in the VHL/HIF-1α interaction pathway? |
Q89752121 | Inactivation of BRM/SMARCA2 sensitizes clear cell renal cell carcinoma to histone deacetylase complex inhibitors |
Q28590550 | Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice |
Q47981361 | Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis |
Q40296387 | Inactivation of von Hippel-Lindau gene induces constitutive phosphorylation of MET protein in clear cell renal carcinoma. |
Q28272109 | Induction of human endometrial cancer cell senescence through modulation of HIF-1alpha activity by EGLN1 |
Q30573857 | Inferring tree models for oncogenesis from comparative genome hybridization data |
Q36549605 | Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells |
Q38342047 | Infrequent alteration of the DPC4 tumor suppressor gene in renal cell carcinoma. |
Q77113259 | Inherited carcinomas of the kidney |
Q34019599 | Inherited epithelial tumors of the kidney: old and new diseases |
Q44043145 | Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein |
Q24800550 | Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth |
Q34549454 | Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain |
Q24336629 | Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein |
Q54283940 | Inhibition of mTORC2 but not mTORC1 up-regulates E-cadherin expression and inhibits cell motility by blocking HIF-2α expression in human renal cell carcinoma. |
Q36074111 | Insulin-like growth factor-1 signaling in renal cell carcinoma |
Q27852382 | Integrated molecular analysis of clear-cell renal cell carcinoma |
Q33799049 | Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma |
Q37696197 | Integrative analysis of protein-coding and non-coding RNAs identifies clinically relevant subtypes of clear cell renal cell carcinoma |
Q53627986 | Integrative tumor board: metastatic renal cell carcinoma: naturopathic medicine. |
Q41242833 | Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression. |
Q37149909 | Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications |
Q40946483 | Intrinsic drug resistance in primary and metastatic renal cell carcinoma |
Q35067209 | Inverse association between programmed death ligand 1 and genes in the VEGF pathway in primary clear cell renal cell carcinoma |
Q36696226 | Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma. |
Q44089850 | Investigation of tumor suppressor genes apart from VHL on 3p by deletion mapping in sporadic clear cell renal cell carcinoma (cRCC). |
Q57272195 | Involvement of multiple loci on chromosome 3 in renal cell cancer development |
Q35891379 | Isoform-specific interactions of the von Hippel-Lindau tumor suppressor protein |
Q34478868 | KLF4, p21 and context-dependent opposing forces in cancer |
Q40002571 | Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression |
Q36675387 | Kidney cancer therapy: new perspectives and avenues |
Q40831882 | Kidney cancer. |
Q36366495 | Kidney cancer: identification of novel targets for therapy |
Q37728343 | Kinase targets in renal-cell carcinomas: reassessing the old and discovering the new. |
Q34589207 | Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN). |
Q92087490 | LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion |
Q37165231 | LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer |
Q92123922 | LRRC19-A Bridge between Selenium Adjuvant Therapy and Renal Clear Cell Carcinoma: A Study Based on Datamining |
Q44763099 | Lack of mutation of the folliculin gene in sporadic chromophobe renal cell carcinoma and renal oncocytoma |
Q38238966 | Landmarks in the diagnosis and treatment of renal cell carcinoma |
Q84696228 | Linking toxicity to the target |
Q33821055 | Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma |
Q57914544 | Loss of HNF1? function in human renal cell carcinoma: Frequent mutations in theVHL gene but not theHNF1? gene |
Q47117026 | Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis |
Q24299088 | Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours |
Q37126195 | Loss of VHL promotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity. |
Q44605433 | Loss of expression of von Hippel-Lindau tumor suppressor protein associated with improved survival in patients with early-stage clear cell renal cell carcinoma |
Q36730935 | Loss of heterozygosity and copy number abnormality in clear cell renal cell carcinoma discovered by high-density affymetrix 10K single nucleotide polymorphism mapping array |
Q73923938 | Loss of heterozygosity at chromosomes 8p, 9p, and 14q is associated with stage and grade of non-papillary renal cell carcinomas |
Q71769244 | Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinoma |
Q72046516 | Loss of heterozygosity on the short arm of chromosome 3 in sporadic, von hippel‐lindau disease‐associated, and familial pheochromocytoma |
Q73227572 | Loss of heterozygosity on the short arm of chromosomes 1 and 3 in sporadic pheochromocytoma and extra-adrenal paraganglioma |
Q74141948 | Loss of imprinting of igf2 in renal-cell carcinomas |
Q33998089 | Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth |
Q44159799 | Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner |
Q61946742 | Losses at 3p common deletion sites in subtypes of kidney tumours: histopathological correlations |
Q27851432 | Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma |
Q53459268 | Low incidence of point mutations in H-, K- and N-ras oncogenes and p53 tumor suppressor gene in renal cell carcinoma and peritoneal mesothelioma of Wistar rats induced by ferric nitrilotriacetate. |
Q44456560 | MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma |
Q91754912 | MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma |
Q28578563 | MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression |
Q37718458 | MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway. |
Q35669189 | MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism |
Q96684667 | Macrophage HIF-1α is an independent prognostic indicator in kidney cancer |
Q71574846 | Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis |
Q38180744 | Management of metastatic kidney cancer in the era of personalized medicine |
Q74639003 | Management of renal cell carcinoma in von Hippel-Lindau disease |
Q36395197 | Management of von Hippel-Lindau-associated kidney cancer |
Q37503817 | Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions |
Q101124442 | Mass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism |
Q36731136 | Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer |
Q28272747 | Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancy |
Q49832801 | Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2α Inhibitor PT2385 In Vivo and In Vitro |
Q38546245 | Metabolic alterations in renal cell carcinoma |
Q24600512 | Metabolism of kidney cancer: from the lab to clinical practice |
Q37453142 | Metachronous bilateral renal cell carcinoma with an interval of more than 10 years |
Q84983264 | Metachronous clear cell carcinoma of the tongue and kidney: a diagnostically challenging coincidence |
Q34417804 | Metastatic clear cell carcinoma of the kidney: therapeutic role of bevacizumab |
Q73048375 | Metastatic renal cell carcinoma in a child: 11-year disease-free survival following surgery |
Q64240759 | Metastatic renal cell carcinoma regains sensitivity to tyrosine kinase inhibitor after nivolumab treatment: A case report |
Q43583310 | Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. |
Q53351901 | Methylation level of the RASSF1A promoter is an independent prognostic factor for clear-cell renal cell carcinoma. |
Q24631957 | Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands |
Q26852641 | MicroRNAs in the pathogenesis of cystic kidney disease |
Q77959493 | Microsatellite analysis reveals deletion of a large region at chromosome 8p in conventional renal cell carcinoma |
Q30786619 | Mining genome sequencing data to identify the genomic features linked to breast cancer histopathology |
Q36484119 | Mitochondrial disorders in renal tumors. |
Q47793757 | Mitotic spindle misorientation in cancer--out of alignment and into the fire |
Q46856592 | Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade |
Q101407217 | Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade |
Q34987420 | Molecular alterations in sporadic breast cancer |
Q73704814 | Molecular analysis of a familial case of renal cell cancer and a t(3;6)(q12;q15) |
Q84571507 | Molecular analysis of germline t(3;6) and t(3;12) associated with conventional renal cell carcinomas indicates their rate-limiting role and supports the three-hit model of carcinogenesis |
Q37332599 | Molecular and cytogenetic insights into the pathogenesis, classification, differential diagnosis, and prognosis of renal epithelial neoplasms |
Q46408470 | Molecular basis of targeted therapy in metastatic renal cancer |
Q28220414 | Molecular basis of the VHL hereditary cancer syndrome |
Q77752042 | Molecular biology of lung cancer |
Q36678672 | Molecular biology of renal cell cancer and the identification of therapeutic targets |
Q35789932 | Molecular classification of renal tumors by gene expression profiling |
Q40971282 | Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma |
Q52828398 | Molecular cytogenetic analysis of 17 renal cancer cell lines: increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas. |
Q47880488 | Molecular detection of von Hippel-Lindau gene mutations in urine and lymph node samples in patients with renal cell carcinoma: potential biomarkers for early diagnosis and postoperative metastatic status |
Q34065685 | Molecular diagnosis and therapy of kidney cancer |
Q35782667 | Molecular differential diagnosis of renal carcinoma: from microscopes to microsatellites |
Q42803057 | Molecular differential diagnosis of renal cell carcinomas by microsatellite analysis |
Q40429882 | Molecular foundations of cancer: New targets for intervention |
Q35636300 | Molecular genetic alterations in adrenal and extra-adrenal pheochromocytomas and paragangliomas |
Q43010632 | Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma |
Q77357835 | Molecular genetic analysis of the von Hippel-Lindau and human peroxisome proliferator-activated receptor gamma tumor-suppressor genes in adenocarcinomas of the gastroesophageal junction |
Q71127418 | Molecular genetic analysis of the von Hippel-Lindau disease (VHL) tumour suppressor gene in gonadal tumours |
Q50092603 | Molecular genetic diagnosis of von Hippel-Lindau disease: analysis of five Japanese families |
Q35022055 | Molecular genetics and histopathologic features of adult distal nephron tumors |
Q33729097 | Molecular genetics of clear-cell renal cell carcinoma |
Q36105155 | Molecular genetics of familial renal cell carcinoma syndromes |
Q35598229 | Molecular genetics of kidney cancer |
Q41720979 | Molecular genetics of renal carcinogenesis |
Q74736163 | Molecular genetics of renal cell carcinoma |
Q26825512 | Molecular marker for predicting treatment response in advanced renal cell carcinoma: does the promise fulfill clinical need? |
Q37099355 | Molecular markers for predicting prognosis of renal cell carcinoma |
Q38131134 | Molecular markers to predict response to therapy |
Q35089301 | Molecular mechanisms of renal development |
Q37000269 | Molecular mechanisms underlying the MiT translocation subgroup of renal cell carcinomas |
Q36492055 | Molecular pathogenetics of renal cancer |
Q33982903 | Molecular sub-classification of renal epithelial tumors using meta-analysis of gene expression microarrays. |
Q73645664 | Molecular targeting of VHL gene pathway in clear cell kidney cancer |
Q34707607 | Molecular-based therapies for renal cell carcinoma |
Q36334896 | Molecularly targeted therapy in renal cell carcinoma |
Q91810878 | Monocarboxylate transporter 1 and monocarboxylate transporter 4 in cancer-endothelial co-culturing microenvironments promote proliferation, migration, and invasion of renal cancer cells |
Q42186975 | Monoclonal antibody G250 targeting CA Ⅸ: Binding specificity, internalization and therapeutic effects in a non-renal cancer model |
Q80464963 | Morphologic and molecular characterization of renal cell carcinoma in children and young adults |
Q38967799 | Morphologic, Molecular, and Taxonomic Evolution of Renal Cell Carcinoma: A Conceptual Perspective With Emphasis on Updates to the 2016 World Health Organization Classification |
Q35753186 | Multiple neuroendocrine tumors of the pancreas in von Hippel-Lindau disease patients: histopathological and molecular genetic analysis |
Q41439628 | Mutagenic and epigenetic effects of DNA methylation |
Q34144574 | Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility |
Q71398601 | Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas |
Q71398598 | Mutation of the Von Hippel-Lindau tumour suppressor gene in capillary haemangioblastomas of the central nervous system |
Q73272320 | Mutation of the p53 tumour suppressor gene occurs preferentially in the chromophobe type of renal cell tumour |
Q51035684 | Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha. |
Q77303558 | Mutation of von Hippel-Lindau tumor suppressor gene in a sporadic endolymphatic sac tumor |
Q50310038 | Mutational analysis of the von hippel lindau gene in clear cell renal carcinomas from tuberous sclerosis complex patients |
Q33682913 | Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas |
Q77985962 | Mutations in the von Hippel-Lindau (VHL) gene refine differential diagnostic criteria in renal cell carcinoma |
Q29937783 | Mutations of the VHL gene in sporadic renal cell carcinoma: definition of a risk factor for VHL patients to develop an RCC |
Q39604051 | Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma |
Q64249111 | N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis |
Q41967990 | NK cells sense tumors, course of disease and treatments: Consequences for NK-based therapies |
Q41605739 | Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2. |
Q34104223 | Needle core biopsies provide ample material for genomic and proteomic studies of kidney cancer: observations on DNA, RNA, protein extractions and VHL mutation detection |
Q37286026 | Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein |
Q35310741 | Nephrotoxicity of recent anti-cancer agents |
Q48196926 | Nestin expression on tumour vessels and tumour-infiltrating macrophages define a poor prognosis subgroup of pt1 clear cell renal cell carcinoma |
Q40961524 | Neurofibromatosis type 2 and von Hippel-Lindau disease: from gene cloning to function |
Q34538603 | Neurological Management of Von Hippel-Lindau Disease |
Q38664266 | New HIF2α inhibitors: potential implications as therapeutics for advanced pheochromocytomas and paragangliomas |
Q44747905 | New antiangiogenic agents for renal cell carcinoma: interferon alfa and thalidomide |
Q36691810 | New drug therapies for advanced renal cell carcinoma |
Q42631757 | New insights into von Hippel-Lindau function highlighted by investigation of the trichloroethylene-induced p.P81S hotspot mutation |
Q37596915 | New treatment approaches in renal cell carcinoma |
Q90609011 | Next Generation Sequencing in Renal Cell Carcinoma: Towards Precision Medicine |
Q34206517 | Next-generation sequencing of translocation renal cell carcinoma reveals novel RNA splicing partners and frequent mutations of chromatin-remodeling genes |
Q36913101 | Nitric oxide and hypoxia |
Q74137968 | No evidence exists for methylation inactivation of the p16 tumor suppressor gene in ovarian carcinogenesis |
Q37822638 | Non-clear cell advanced kidney cancer: is there a gold standard? |
Q35692212 | Non-diethylstilbestrol exposed vaginal clear cell adenocarcinoma has a common molecular profile with ovarian clear cell adenocarcinoma: A case report |
Q57212292 | Non-myeloablative allogeneic stem cell transplantation for metastatic renal cell carcinoma |
Q34409187 | Novel approaches in the therapy of metastatic renal cell carcinoma. |
Q37685596 | Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer. |
Q36045973 | Novel kinase inhibitors in renal cell carcinoma: progressive development of static agents |
Q82562299 | Novel kinase inhibitors in renal cell carcinoma: progressive development of static agents |
Q38467569 | Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinomas |
Q53330035 | Novel somatic mutations of the VHL gene in an erythropoietin-producing renal carcinoma associated with secondary polycythemia and elevated circulating endothelial progenitor cells. |
Q34392028 | Novel three missense mutations observed in Von Hippel-Lindau gene in a patient reported with renal cell carcinoma |
Q34603364 | Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma |
Q37701211 | Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density |
Q24651568 | Nucleostemin mRNA is expressed in both normal and malignant renal tissues |
Q33636256 | Obesity is associated with a higher risk of clear-cell renal cell carcinoma than with other histologies |
Q84582207 | Oligoarray comparative genomic hybridization of renal cell tumors that developed in patients with acquired cystic renal disease |
Q91531330 | On the Shoulders of Giants: The Evolution of Renal Cell Carcinoma Treatment-Cytokines, Targeted Therapy, and Immunotherapy |
Q55618938 | Oncogenic miR-425-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma. |
Q38008023 | Oncolytic virotherapy for renal cell carcinoma: a novel treatment paradigm? |
Q53320370 | Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure. |
Q36016797 | Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma |
Q43980382 | Overall survival in patients with metastatic renal cell carcinoma initially treated with bevacizumab plus interferon‐α2a and subsequent therapy with tyrosine kinase inhibitors: a retrospective analysis of the phase III AVOREN trial |
Q38822454 | Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer. |
Q38357715 | Overexpression of KIT in chromophobe renal cell carcinoma |
Q42549996 | Overexpression of integrin-associated protein (CD47) in rat kidney treated with a renal carcinogen, ferric nitrilotriacetate |
Q51582002 | Overexpression of miR-210, a downstream target of HIF1α, causes centrosome amplification in renal carcinoma cells. |
Q54765102 | Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas. |
Q35565483 | Oxygen sensing in cancer |
Q34611016 | Oxygen sensors and angiogenesis |
Q28647626 | Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein |
Q38122565 | PBRM1 and BAP1 as novel targets for renal cell carcinoma |
Q37596748 | PD-L1 Expression in Clear Cell Renal Cell Carcinoma: An Analysis of Nephrectomy and Sites of Metastases |
Q92943300 | PGC1α suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expression |
Q37749481 | PHD2 in tumour angiogenesis |
Q38889724 | PI3Kβ inhibitor TGX221 selectively inhibits renal cell carcinoma cells with both VHL and SETD2 mutations and links multiple pathways |
Q50784588 | PRCC-TFE3 renal cell carcinoma in a boy with a history of contralateral mesoblastic nephroma. |
Q91596984 | PRDM16 suppresses HIF-targeted gene expression in kidney cancer |
Q91560799 | Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis |
Q61226159 | Pan-cancer genomic amplifications underlie a Wnt hyperactivation phenotype associated with stem cell-like features leading to poor prognosis |
Q34364668 | Papillary renal cell carcinoma: analysis of germline mutations in the MET proto-oncogene in a clinic-based population |
Q38478525 | Papillary renal cell carcinoma: quantitation of chromosomes 7 and 17 by FISH, analysis of chromosome 3p for LOH, and DNA ploidy |
Q85072259 | Paraffin-embedded tissue is less accurate than frozen section analysis for determining VHL mutational status in sporadic renal cell carcinoma |
Q36285539 | Parathyroid hormone-related protein in human renal cell carcinoma |
Q38447341 | Pathologic T1 clear cell renal cell carcinoma: insulin-like growth factor-I receptor expression and disease-specific survival. |
Q54135611 | Pathological and Clinical Features and Management of Central Nervous System Hemangioblastomas in von Hippel-Lindau Disease. |
Q38030685 | Pathology of genitourinary malignancies: implications for clinical management |
Q36713480 | Pathways of dysregulation in renal cell carcinoma: rational approaches to development of novel treatment. |
Q38483900 | Patterns of aneuploidy in stage IV clear cell renal cell carcinoma revealed by comparative genomic hybridization and spectral karyotyping |
Q41127733 | Pax-2, kidney development, and oncogenesis |
Q34207205 | Pazopanib for the treatment of patients with advanced renal cell carcinoma |
Q37862259 | Pazopanib for the treatment of renal cancer |
Q37748042 | Pazopanib: Clinical development of a potent anti-angiogenic drug |
Q58104072 | Perioperative Therapy in Renal Cell Carcinoma: What Do We Know, What Have We Learned, What's Next? |
Q92272936 | Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma |
Q37457275 | Perspective: Beyond the genome |
Q39095194 | Pharmacotherapy for treating metastatic clear cell renal cell carcinoma |
Q79318186 | Phase II study of lenalidomide in patients with metastatic renal cell carcinoma |
Q33813718 | Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206 |
Q36047391 | Pheochromocytoma and functional paraganglioma syndrome: no longer the 10% tumor |
Q34497997 | Pleiotropic stromal effects of vascular endothelial growth factor receptor 2 antibody therapy in renal cell carcinoma models |
Q35592187 | Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma |
Q45101302 | Polymorphism in protein tyrosine phosphatase receptor delta is associated with the risk of clear cell renal cell carcinoma. |
Q77308149 | Polyploidization and losses of chromosomes 1, 2, 6, 10, 13, and 17 in three cases of chromophobe renal cell carcinomas |
Q54710672 | Positive correlation between allelic loss at chromosome 14q24-31 and poor prognosis of patients with renal cell carcinoma. |
Q78052855 | Positive expression of HIF-2alpha/EPAS1 in invasive bladder cancer |
Q37285776 | Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene |
Q38970282 | Precision medicine from the renal cancer genome |
Q90737500 | Preclinical rationale and clinical efficacy of antiangiogenic therapy and immune checkpoint blockade combination therapy in urogenital tumors |
Q83462674 | Preimplantation genetic diagnosis using fluorescent in situ hybridization for cancer predisposition syndromes caused by microdeletions |
Q89793198 | Prevalence and clinical significance of VHL mutations and 3p25 deletions in renal tumor subtypes |
Q41659630 | Prevalence of microscopic lesions in grossly normal renal parenchyma from patients with von Hippel-Lindau disease, sporadic renal cell carcinoma and no renal disease: clinical implications |
Q24813050 | Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study |
Q40841893 | Prevalence, morphology and biology of renal cell carcinoma in von Hippel-Lindau disease compared to sporadic renal cell carcinoma |
Q47272377 | Primary capillary hemangioblastoma of peripheral soft tissues |
Q78213661 | Processed pseudogene from the von Hippel-Lindau disease gene is located on human chromosome 1 |
Q26827319 | Profile of tivozanib and its potential for the treatment of advanced renal cell carcinoma |
Q26749393 | Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis |
Q92154621 | Prognostic and Predictive Value of PBRM1 in Clear Cell Renal Cell Carcinoma |
Q36816038 | Prognostic biomarkers in renal cell carcinoma |
Q44272543 | Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials |
Q50688764 | Prognostic significance of erythropoietin expression in human renal cell carcinoma. |
Q40419210 | Prognostic value of vascular endothelial growth factor (VEGF), VEGF receptor 2, platelet-derived growth factor-β (PDGF-β), and PDGF-β receptor expression in papillary renal cell carcinoma |
Q90368775 | Prolyl-hydroxylase inhibitors for the treatment of anemia in chronic kidney disease |
Q54583873 | Promoter hypermethylation profile of kidney cancer with new proapoptotic p53 target genes and clinical implications. |
Q39718603 | Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. |
Q36585720 | Proteostasis modulators prolong missense VHL protein activity and halt tumor progression |
Q36910720 | Pseudohypoxic pathways in renal cell carcinoma |
Q42662359 | Quantifying cancer progression with conjunctive Bayesian networks |
Q54707675 | Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. |
Q48123819 | RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition. |
Q35924637 | RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis |
Q26853207 | RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis |
Q73561184 | Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2 |
Q34779834 | Rapid mutation scanning of genes associated with familial cancer syndromes using denaturing high-performance liquid chromatography |
Q38071583 | Rational therapy for renal cell carcinoma based on its genetic targets |
Q46591527 | Re: efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma |
Q89839542 | Recent advances in the biology of tumour hypoxia with relevance to diagnostic practice and tissue-based research |
Q38108392 | Recent advances in the treatment of metastatic renal cell carcinoma |
Q47899328 | Recent developments in small molecule therapies for renal cell carcinoma |
Q34138129 | Recessive oncogenes: current status |
Q102321421 | Recommendations by the Asian Pacific Society of Nephrology (APSN) on the appropriate use of HIF-PH inhibitors |
Q38171376 | Recommendations for the clinical and radiological evaluation of response to treatment in metastatic renal cell cancer. |
Q35462032 | Reconsideration of biallelic inactivation of the VHL tumour suppressor gene in hemangioblastomas of the central nervous system |
Q36741647 | Recurrence of renal cell carcinoma diagnosed using contralateral adrenal biopsy with endoscopic ultrasound-guided fine-needle aspiration. |
Q39052352 | Reduced expression of Slit2 in renal cell carcinoma |
Q28478577 | Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion |
Q71937674 | Refining a proximal breakpoint cluster at chromosome 3p11.2 in non-papillary renal cell carcinomas |
Q92390135 | Regulation of Stem Cells by Cullin-RING Ligase |
Q38881445 | Regulation of cancer stem cells by RING finger ubiquitin ligases |
Q24523680 | Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2 |
Q34530199 | Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. |
Q24301119 | Regulation of receptor for activated C kinase 1 protein by the von Hippel–Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasiveness |
Q42288643 | Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma |
Q40812865 | Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPAS1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma |
Q35792041 | Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression. |
Q57049453 | Reliable gene mutation prediction in clear cell renal cell carcinoma through multi-classifier multi-objective radiogenomics model |
Q38854862 | Renal Carcinogenesis, Tumor Heterogeneity, and Reactive Oxygen Species: Tactics Evolved |
Q74453899 | Renal Cell Carcinoma Metastatic to the Thyroid Gland: A Comparative Molecular Study Between the Primary and the Metastatic Tumor |
Q41018679 | Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status |
Q58104118 | Renal Cell Carcinoma in the Era of Precision Medicine: From Molecular Pathology to Tissue-Based Biomarkers |
Q58376206 | Renal Tumors in the Birt-Hogg-Dubé Syndrome |
Q47266916 | Renal cancer in families with hereditary renal cancer: prospective analysis of a tumor size threshold for renal parenchymal sparing surgery |
Q38125117 | Renal cancer in von Hippel-Lindau disease and related syndromes |
Q35660579 | Renal cancer treatment: a review of the literature. |
Q37153397 | Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy |
Q34468262 | Renal cancer: molecular mechanisms and newer therapeutic options |
Q38185177 | Renal carcinoma pharmacogenomics and predictors of response: Steps toward treatment individualization. |
Q30235364 | Renal cell carcinoma |
Q73669457 | Renal cell carcinoma |
Q56019530 | Renal cell carcinoma |
Q81628401 | Renal cell carcinoma |
Q82656838 | Renal cell carcinoma |
Q41235086 | Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus |
Q52584899 | Renal cell carcinoma for the nephrologist. |
Q42700879 | Renal cell carcinoma histological subtype distribution differs by age, gender, and tumor size in coastal Chinese patients |
Q77223839 | Renal cell carcinoma in children with diffuse cystic hyperplasia of the kidneys |
Q53352910 | Renal cell carcinoma risk in type 2 von Hippel-Lindau disease correlates with defects in pVHL stability and HIF-1alpha interactions. |
Q37998166 | Renal cell carcinoma with clear cell and papillary features |
Q82333868 | Renal cell carcinoma with mixed features of papillary and clear cell cytomorphology: a fluorescent in situ hybridization study |
Q72033651 | Renal cell carcinoma. Cytogenetic analysis of tumors and cell lines |
Q52724797 | Renal cell carcinoma: a review of biology and pathophysiology. |
Q42526854 | Renal cell carcinoma: allelic loss at chromosome 9 using the fluorescent multiplex-polymerase chain reaction technique |
Q34003335 | Renal cell carcinoma: where will the state-of-the-art lead us? |
Q36446896 | Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor |
Q71974434 | Renal cysts, renal cancer and von Hippel-Lindau disease |
Q33942236 | Renal toxicity and carcinogenicity of trichloroethylene: key results, mechanisms, and controversies |
Q34394356 | Renal-cell carcinoma |
Q35214956 | Repeat partial nephrectomy: surgical, functional and oncological outcomes |
Q36898383 | Report on the ISBTC mini-symposium on biologic effects of targeted therapeutics. |
Q38274934 | Resistance to sunitinib in renal cell carcinoma: From molecular mechanisms to predictive markers and future perspectives |
Q53211749 | Response rates and adverse effects of continuous once-daily sunitinib in patients with advanced renal cell carcinoma: a single-center study in Turkey. |
Q34387488 | Review: cellular substrates of the eukaryotic chaperonin TRiC/CCT. |
Q35990141 | Role of VHL gene mutation in human cancer |
Q33918504 | Role of chromosome 3p12-p21 tumour suppressor genes in clear cell renal cell carcinoma: analysis of VHL dependent and VHL independent pathways of tumorigenesis |
Q45230739 | Role of exon 2-encoded beta -domain of the von Hippel-Lindau tumor suppressor protein |
Q37164607 | Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor |
Q33307879 | Role of the ubiquitin proteasome system in renal cell carcinoma |
Q28348758 | Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis |
Q28208943 | Roles of SCF and VHL ubiquitin ligases in regulation of cell growth |
Q39544675 | SAR studies of 4-pyridyl heterocyclic anilines that selectively induce autophagic cell death in von Hippel-Lindau-deficient renal cell carcinoma cells |
Q92977938 | SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12 |
Q36694377 | SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma |
Q31030157 | SU11248 and AG013736: current data and future trials in renal cell carcinoma |
Q28272429 | Safety and tolerability of pazopanib in the treatment of renal cell carcinoma |
Q35705266 | Sarcomatoid renal cell carcinoma: a comprehensive review of the biology and current treatment strategies |
Q73130567 | Screening for renal carcinoma associated mutations in the von Hippel-Lindau tumor suppressor gene by temperature gradient gel electrophoresis |
Q34318015 | Searching for the hereditary causes of renal-cell carcinoma |
Q40019147 | Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions |
Q74509439 | Selection of mutant CHO cells with constitutive activation of the HIF system and inactivation of the von Hippel-Lindau tumor suppressor |
Q39697199 | Selective inhibition of carbonic anhydrase IX decreases cell proliferation and induces ceramide-mediated apoptosis in human cancer cells. |
Q38971171 | Senescence induction in renal carcinoma cells by Nutlin-3: a potential therapeutic strategy based on MDM2 antagonism |
Q47862165 | Sequencing of the von Hippel-Lindau gene in canine renal carcinoma |
Q46008845 | Sequential sorafenib and sunitinib for renal cell carcinoma. |
Q40038925 | Signaling inhibitors in metastatic renal cell carcinoma |
Q95935869 | Significance of PI3K signalling pathway in clear cell renal cell carcinoma in relation to VHL and HIF status |
Q95807715 | Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer |
Q47101376 | Single nucleotide polymorphisms as prognostic and predictive biomarkers in renal cell carcinoma. |
Q34618828 | Single nucleotide polymorphisms in the Wilms' tumour gene 1 in clear cell renal cell carcinoma |
Q36895413 | Small molecule signal transduction inhibitors for the treatment of solid tumors |
Q39722266 | Software and database for the analysis of mutations in the VHL gene |
Q34286240 | Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location. |
Q27634727 | Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide |
Q35238725 | Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors. |
Q73422570 | Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell |
Q71820124 | Somatic mutations of von Hippel‐Lindau (VHL) tumor‐suppressor gene in european kidney cancers |
Q77649713 | Somatic point mutation of the wild-type allele detected in tumors of patients with VHL germline deletion |
Q44178387 | Somatic von Hippel-Lindau disease gene mutation in clear-cell renal carcinomas associated with end-stage renal disease/acquired cystic disease of the kidney |
Q34731411 | Somatic von Hippel-Lindau mutation in clear cell papillary cystadenoma of the epididymis |
Q36407379 | Sorafenib |
Q39431060 | Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy |
Q39637482 | Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling. |
Q38431094 | Sorafenib with interferon alfa-2b as first-line treatment of advanced renal carcinoma: a phase II study of the Southwest Oncology Group |
Q36817095 | Sorafenib: delivering a targeted drug to the right targets |
Q53607782 | Spoke-wheel-like enhancement as an important imaging finding of chromophobe cell renal carcinoma: a retrospective analysis on computed tomography and magnetic resonance imaging studies. |
Q71545608 | Spontaneous renal tubular carcinoma in Fischer-344 rat littermates |
Q33940347 | Sporadic endocrine tumours and their relationship to the hereditary endocrine neoplasia syndromes |
Q79387201 | Sporadic human renal tumors display frequent allelic imbalances and novel mutations of the HRPT2 gene |
Q24630685 | State of the science: an update on renal cell carcinoma |
Q39975802 | State-of-the-art treatment of metastatic renal cell carcinoma. |
Q38760019 | Stem cells, biomarkers and genetic profiling: approaching future challenges in Urology |
Q36367103 | Stratification of clear cell renal cell carcinoma (ccRCC) genomes by gene-directed copy number alteration (CNA) analysis |
Q36945200 | Structural insights into the folding defects of oncogenic pVHL lead to correction of its function in vitro |
Q31085777 | Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines |
Q22009393 | Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function |
Q41194143 | Studies of oncogene activation and tumor suppressor gene inactivation in normal and neoplastic rodent tissue |
Q35044182 | Studying cancer families to identify kidney cancer genes |
Q37401350 | Subcellular dynamics of the VHL tumor suppressor: on the move for HIF degradation |
Q41011329 | Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent |
Q34969974 | Subclassification of renal cell neoplasms: an update for the practising pathologist |
Q46516706 | Successful implementation of the randomized discontinuation trial design: an application to the study of the putative antiangiogenic agent carboxyaminoimidazole in renal cell carcinoma--CALGB 69901. |
Q43194981 | Sunitinib |
Q37797460 | Sunitinib for Metastatic Renal Cell Carcinoma |
Q38206453 | Sunitinib in the treatment of advanced solid tumors |
Q28282757 | Sunitinib versus interferon alfa in metastatic renal-cell carcinoma |
Q35899174 | Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma |
Q37829355 | Suppression of T-cell responses by tumor metabolites |
Q54605056 | Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element. |
Q90558473 | Suppressive effects of iron chelation in clear cell renal cell carcinoma and their dependency on VHL inactivation |
Q57545397 | Surgical and Medical Options in the Management of Renal Cell Carcinoma |
Q46358494 | Surgical decision-making affected by clinical and genetic screening of a novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors |
Q36395004 | Surgical intervention in patients with metastatic renal cancer: current status of metastasectomy and cytoreductive nephrectomy |
Q37341139 | Surgical management of von Hippel-Lindau disease: urologic considerations |
Q33848569 | Surgical pathology of renal epithelial neoplasms: recent advances and current status |
Q90092590 | Surgical treatment for Xp11.2 translocation renal cell carcinoma with venous thrombus: A STROBE-compliant study |
Q51625377 | Synchronous Metastatic Clear-Cell Renal Cell Carcinoma: A Distinct Morphologic, Immunohistochemical, and Molecular Phenotype. |
Q38709495 | Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs |
Q24563543 | Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein |
Q38216599 | Systemic therapy for non-clear cell renal cell carcinomas: a systematic review and meta-analysis |
Q37575635 | Systemic therapy of kidney cancer: tyrosine kinase inhibitors, antiangiogenesis or IL-2? |
Q47591804 | TCF21 hypermethylation regulates renal tumor cell clonogenic proliferation and migration |
Q35293660 | TFE3 Translocation-Associated Renal Cell Carcinoma Presenting as Avascular Necrosis of the Femur in a 19-Year-Old Patient: Case Report and Review of the Literature |
Q47904057 | THSD7A expression in human cancer |
Q57291492 | TP53, EGFR, and KRAS mutations in relation to VHL inactivation and lifestyle risk factors in renal-cell carcinoma from central and eastern Europe |
Q26995391 | Targeted therapies and the treatment of non-clear cell renal cell carcinoma |
Q39425380 | Targeted therapies for renal cell carcinoma |
Q37796392 | Targeted therapies of cancer: Angiogenesis inhibition seems not enough |
Q39914671 | Targeted therapy for metastatic renal cell carcinoma: current treatment and future directions |
Q36597063 | Targeted therapy for renal cell carcinoma: a new therapeutic paradigm |
Q39943677 | Targeted therapy for the loss of von Hippel-Lindau in renal cell carcinoma: a novel molecule that induces autophagic cell death |
Q38750776 | Targeting HIF-2 α in clear cell renal cell carcinoma: A promising therapeutic strategy |
Q64253749 | Targeting Tyrosine kinases in Renal Cell Carcinoma: "New Bullets against Old Guys" |
Q36380193 | Targeting VEGF in cancer therapy |
Q41930187 | Targeting ion transport in cancer |
Q33607412 | Targeting of tumor growth and angiogenesis underlies the enhanced antitumor activity of lenvatinib in combination with everolimus |
Q37684974 | Targeting renal cell carcinoma with a HIF-2 antagonist. |
Q37575541 | Targeting the IGF1 axis in cancer proliferation |
Q38668940 | Targeting the RhoGTPase/ROCK pathway for the treatment of VHL/HIF pathway-driven cancers. |
Q90003131 | Targeting the TR4 nuclear receptor-mediated lncTASR/AXL signaling with tretinoin increases the sunitinib sensitivity to better suppress the RCC progression |
Q38122564 | Targeting the hepatocyte growth factor/c-Met signaling pathway in renal cell carcinoma |
Q40118469 | Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells. |
Q28209316 | Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein |
Q51794179 | Ternary complex formation of pVHL, elongin B and elongin C visualized in living cells by a fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy technique. |
Q91666595 | The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications |
Q62606055 | The Chromatin Remodeling Gene ARID1A Is a New Prognostic Marker in Clear Cell Renal Cell Carcinoma |
Q88633619 | The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma |
Q51229854 | The DART Study: Results from the Dose-Escalation and Expansion Cohorts Evaluating the Combination of Dalantercept plus Axitinib in Advanced Renal Cell Carcinoma. |
Q48027284 | The Elongin BC complex and the von Hippel-Lindau tumor suppressor protein |
Q41509834 | The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B. |
Q24321912 | The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers |
Q40318935 | The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinoma |
Q37762200 | The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization |
Q55067278 | The Heidelberg classification of renal cell tumours. |
Q92020314 | The Metabolic Basis of Kidney Cancer |
Q30277177 | The Nephrologist's Tumor: Basic Biology and Management of Renal Cell Carcinoma |
Q54299389 | The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer. |
Q88733594 | The Role of DNA Methylation in Renal Cell Carcinoma |
Q35971082 | The Role of Elongin BC-Containing Ubiquitin Ligases |
Q58199668 | The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma |
Q58199693 | The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma |
Q33683959 | The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma |
Q24676311 | The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity |
Q53088574 | The VHL short variant involves in protein quality control. |
Q37064867 | The VHL tumor suppressor and HIF: insights from genetic studies in mice |
Q36134573 | The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting. |
Q80282025 | The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma |
Q24634592 | The VHL tumor suppressor: master regulator of HIF |
Q77572384 | The VHL tumour-suppressor gene paradigm |
Q92637492 | The adjuvant treatment of kidney cancer: a multidisciplinary outlook |
Q51002180 | The allele frequency of two single nucleotide polymorphisms in the von Hippel-Lindau (VHL) tumor suppressor gene in the Taiwanese population. |
Q73267658 | The allelic loss of chromosome 3p25 with c‐myc gain is related to the development of clear‐cell renal cell carcinoma |
Q43026364 | The application of cytogenetics and fluorescence in situ hybridization to fine-needle aspiration in the diagnosis and subclassification of renal neoplasms |
Q41899102 | The bevacizumab experience in advanced renal cell carcinoma |
Q36313089 | The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis |
Q37201797 | The clinical implications of the genetics of renal cell carcinoma |
Q55067670 | The concise handbook of family cancer syndromes. Mayo Familial Cancer Program. |
Q44043146 | The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma |
Q79240962 | The correlation between the tumor necrosis and renal artery changes in renal cell carcinoma |
Q39257795 | The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney. |
Q39021700 | The epigenetic landscape of renal cancer |
Q37770362 | The evolving field of tyrosine kinase inhibitors in the treatment of endocrine tumors. |
Q36825195 | The evolving role of surgery for advanced renal cell carcinoma in the era of molecular targeted therapy |
Q39257401 | The experimental renal cell carcinoma model in the chick embryo |
Q33536033 | The genetic basis of breast cancer and its clinical implications |
Q36048466 | The genetic basis of cancer of kidney cancer: implications for gene-specific clinical management |
Q35591611 | The genetic basis of cancer of the kidney |
Q34087148 | The genetic basis of kidney cancer: a metabolic disease |
Q36067684 | The genetic basis of pheochromocytoma and paraganglioma: implications for management |
Q35210970 | The genetic basis of renal cell carcinoma |
Q34330265 | The genetic basis of renal epithelial tumors: advances in research and its impact on prognosis and therapy |
Q80890715 | The genetic make-up of renal cell tumors |
Q35928846 | The growing family of hereditary renal cell carcinoma |
Q35454776 | The impact of molecular genetic analysis of the VHL gene in patients with haemangioblastomas of the central nervous system |
Q28582367 | The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex |
Q39404028 | The interactome of CCT complex - A computational analysis |
Q88937572 | The loss of BAP1 protein expression predicts poor prognosis in patients with nonmetastatic clear cell renal cell carcinoma with inferior vena cava tumor thrombosis |
Q52094824 | The management of familial breast cancer. |
Q36437759 | The molecular basis of von Hippel-Lindau disease |
Q38131130 | The molecular biology of renal cell carcinoma |
Q96767193 | The oncogenic role of MUC12 in RCC progression depends on c-Jun/TGF-β signalling |
Q96828838 | The pVHL neglected functions, a tale of hypoxia-dependent and -independent regulations in cancer |
Q48345594 | The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma |
Q43244499 | The pVHL172 isoform is not a tumor suppressor and up-regulates a subset of pro-tumorigenic genes including TGFB1 and MMP13. |
Q40278749 | The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy |
Q36409967 | The place of VEGF inhibition in the current management of renal cell carcinoma. |
Q101154906 | The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation |
Q28296790 | The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha |
Q35808120 | The relationship between renal tumor size and metastases in patients with von Hippel-Lindau disease |
Q34235680 | The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy |
Q33955367 | The role of angiogenesis in prostate and other urologic cancers: a review |
Q36121341 | The role of components of the chromatin modification machinery in carcinogenesis of clear cell carcinoma of the ovary (Review) |
Q93191323 | The role of endothelial colony forming cells in kidney cancer's pathogenesis, and in resistance to anti-VEGFR agents and mTOR inhibitors: A speculative review |
Q48378117 | The role of surgery in clinical management of patients with metastatic papillary renal cell carcinoma |
Q77936208 | The role of the FHIT/FRA3B locus in cancer |
Q35794374 | The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma |
Q38001221 | The surgical approach to multifocal renal cancers: hereditary syndromes, ipsilateral multifocality, and bilateral tumors |
Q73863787 | The tcf17 gene at chromosome 5q is not involved in the development of conventional renal cell carcinoma |
Q39165782 | The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma |
Q22009936 | The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis |
Q90573376 | The von Hippel Lindau tumour suppressor gene is a novel target of E2F4-mediated transcriptional repression in preeclampsia |
Q43838634 | The von Hippel-Lindau (VHL) disease tumor-suppressor gene is not mutated in nasopharyngeal carcinomas |
Q35564185 | The von Hippel-Lindau Gene, Kidney Cancer, and Oxygen Sensing |
Q99569784 | The von Hippel-Lindau Tumor Suppressor Gene: Implications and Therapeutic Opportunities |
Q37272653 | The von Hippel-Lindau gene: turning discovery into therapy |
Q34087732 | The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression |
Q37240022 | The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL). |
Q28206541 | The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription |
Q28203455 | The von Hippel-Lindau tumor suppressor gene |
Q33959078 | The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells |
Q34744818 | The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal |
Q40023447 | The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity |
Q40914048 | The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2. |
Q35080738 | The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells |
Q41376765 | The von Hippel-Lindau tumor suppressor gene. A rare and intriguing disease opening new insight into basic mechanisms of carcinogenesis |
Q30480543 | The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth |
Q28292043 | The von Hippel-Lindau tumor suppressor protein influences microtubule dynamics at the cell periphery |
Q35201819 | The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity |
Q34748818 | The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix |
Q24304165 | The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1 |
Q35863138 | The von Hippel-Lindau tumour suppressor gene: uncovering the expression of the pVHL172 isoform |
Q33656394 | The von Hippel-Lindau tumour suppressor protein: new perspectives |
Q58068759 | TheVon Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas |
Q26747806 | Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer |
Q46863834 | Therapy strategies for advanced renal cell carcinoma |
Q96582600 | Third-line sunitinib treatment in a VHL-mutated metastatic intrahepatic cholangiocarcinoma: a case report and literature review |
Q78014839 | This month in investigative urology. Kidney cancer: novel model for cancer genetics and therapy |
Q44955205 | Time to disease progression to evaluate a novel protein kinase C inhibitor, UCN-01, in renal cell carcinoma |
Q53313789 | Timeline: Chemotherapy and the war on cancer. |
Q38114944 | Tivozanib for the treatment of metastatic renal cancer |
Q22254253 | Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila |
Q37353465 | Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease |
Q24530637 | Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein |
Q47109274 | Transferrin receptor 1 upregulation in primary tumor and downregulation in benign kidney is associated with progression and mortality in renal cell carcinoma patients |
Q46735182 | Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib |
Q64981713 | Treatment of renal-cell cancer by transplantation of allogeneic stem cells. |
Q33385981 | Treatment outcomes of sunitinib treatment in advanced renal cell carcinoma patients: a single cancer center experience in Korea |
Q36398114 | Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma |
Q85849574 | Tubulocystic renal cell carcinoma: is there a rational reason for targeted therapy using angiogenic inhibition? Analysis of seven cases |
Q43739592 | Tumor VEGF expression correlates with tumor stage and identifies prognostically different groups in patients with clear cell renal cell carcinoma |
Q37846387 | Tumor biology and prognostic factors in renal cell carcinoma |
Q35574224 | Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase |
Q91967463 | Tumor sequencing is useful to refine the analysis of germline variants in unexplained high-risk breast cancer families |
Q28254125 | Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma |
Q33788736 | Tumor suppressor genes in ophthalmology |
Q58323648 | Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth |
Q34299645 | Tumor suppressor von Hippel-Lindau (VHL) stabilization of Jade-1 protein occurs through plant homeodomains and is VHL mutation dependent. |
Q28206723 | Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers |
Q41320477 | Tumour suppression by the human von Hippel-Lindau gene product |
Q37610081 | Two cases of recurrent ovarian clear cell carcinoma treated with sorafenib |
Q73111250 | Two distinct phenotypes caused by two different missense mutations in the same codon of the VHL gene |
Q71747291 | Two regions of homozygosity on chromosome 3p in squamous cell carcinoma of the head and neck: comparison with cytogenetic analysis |
Q34208511 | Two single nucleotide polymorphisms in the von Hippel-Lindau tumor suppressor gene in Taiwanese with renal cell carcinoma |
Q24321830 | UBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor gene |
Q35082720 | Ubiquitin pathway in VHL cancer syndrome |
Q34152646 | Ubiquitin-dependent proteolysis: its role in human diseases and the design of therapeutic strategies |
Q34115236 | Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization |
Q38265657 | Ubiquitination in disease pathogenesis and treatment |
Q64060129 | Ubiquitination of MAP1LC3B by pVHL is associated with autophagy and cell death in renal cell carcinoma |
Q24291981 | Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein |
Q88976865 | Ubiquitination: Friend and foe in cancer |
Q41765603 | Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death. |
Q38214357 | Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity |
Q26852398 | Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment |
Q36397654 | Understanding the importance of smart drugs in renal cell carcinoma |
Q37765586 | Understanding the molecular genetics of renal cell neoplasia: implications for diagnosis, prognosis and therapy |
Q35789042 | Unique patterns of allelic imbalance distinguish type 1 from type 2 sporadic papillary renal cell carcinoma |
Q34456711 | Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function |
Q28140184 | Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function |
Q37642798 | Update on novel agents in renal cell carcinoma |
Q37165968 | Update on the medical treatment of metastatic renal cell carcinoma |
Q73461795 | Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms |
Q35038994 | Use of the spontaneous Tsc2 knockout (Eker) rat model of hereditary renal cell carcinoma for the study of renal carcinogens |
Q37774569 | Using Molecular Biology to Develop Drugs for Renal Cell Carcinoma |
Q44011303 | VEGF pathway-targeted therapy for advanced renal cell carcinoma: a meta-analysis of randomized controlled trials |
Q34406737 | VEGF-targeted therapy in metastatic renal cell carcinoma |
Q36409204 | VEGF-targeted therapy in renal cell carcinoma: active drugs and active choices |
Q35332976 | VEGFR-1 Expression Relates to Fuhrman Nuclear Grade of Clear Cell Renal Cell Carcinoma |
Q45770745 | VHL and HIF-1α: gene variations and prognosis in early-stage clear cell renal cell carcinoma |
Q33862155 | VHL and PTEN loss coordinate to promote mouse liver vascular lesions |
Q33816341 | VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis |
Q53375202 | VHL down-regulation and differential localization as mechanisms in tumorigenesis. |
Q46268484 | VHL gene alterations in Italian patients with isolated renal cell carcinomas |
Q43728214 | VHL gene alterations in renal cell carcinoma patients: novel hotspot or founder mutations and linkage disequilibrium |
Q37393004 | VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy |
Q54627123 | VHL mutations and dysregulation of pVHL- and PTEN-controlled pathways in multilocular cystic renal cell carcinoma. |
Q27824781 | VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma |
Q44921292 | VHL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference? |
Q81404373 | VHL protein alterations in sporadic renal cell carcinoma |
Q73707868 | VHL tumor suppressor regulates Cl-/HCO3- exchange and Na+/H+ exchange activities in renal carcinoma cells |
Q34455226 | VHL, the story of a tumour suppressor gene |
Q58584059 | VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function |
Q33568494 | VHL-gene deletion in single renal tubular epithelial cells and renal tubular cysts: further evidence for a cyst-dependent progression pathway of clear cell renal carcinoma in von Hippel-Lindau disease |
Q37166626 | VHLdb: A database of von Hippel-Lindau protein interactors and mutations |
Q92070638 | VON HIPPEL-LINDAU DISEASE: Update on Pathogenesis and Systemic Aspects |
Q37327806 | Validation of DAB2IP methylation and its relative significance in predicting outcome in renal cell carcinoma |
Q33712289 | Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: critical reassessment of YBX3/ZONAB/CSDA expression |
Q39840596 | Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer |
Q55071101 | Variants in angiogenesis-related genes and the risk of clear cell renal cell carcinoma. |
Q74455542 | Vascular endothelial growth factor overexpression is correlated with von Hippel-Lindau tumor suppressor gene inactivation in patients with sporadic renal cell carcinoma |
Q40106684 | Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model |
Q37463922 | Vascular endothelial growth factor-targeted therapy in metastatic renal cell carcinoma |
Q34091273 | Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. |
Q35584310 | Visceral fat area as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with antiangiogenic agents |
Q56068021 | Von Hippel Lindau Syndrome |
Q90184377 | Von Hippel-Lindau "Black Forest" mutation inherited in a large Chinese family |
Q55110633 | Von Hippel-Lindau Disease. |
Q56874444 | Von Hippel-Lindau Syndrome |
Q72201412 | Von Hippel-Lindau disease |
Q83009175 | Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma |
Q51971299 | Von Hippel-Lindau disease. |
Q52372308 | Von Hippel-Lindau disease. |
Q54863226 | Von Hippel-Lindau disease. |
Q34305239 | Von Hippel-Lindau disease: clinical and molecular perspectives |
Q34448830 | Von Hippel-Lindau disease: gene to bedside |
Q35041278 | Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function |
Q41547229 | Von Hippel-Lindau syndrome: hereditary cancer arising from inherited mutations of the VHL tumor suppressor gene |
Q34278652 | Von Hippel-Lindau: how a rare disease illuminates cancer biology |
Q44320068 | Warburg phenotype in renal cell carcinoma: high expression of glucose-transporter 1 (GLUT-1) correlates with low CD8(+) T-cell infiltration in the tumor |
Q36842042 | What is standard initial systemic therapy in metastatic renal cell carcinoma? |
Q26827754 | When ubiquitin meets NF-κB: a trove for anti-cancer drug development |
Q88555345 | Wild-type VHL Clear Cell Renal Cell Carcinomas Are a Distinct Clinical and Histologic Entity: A 10-Year Follow-up |
Q21245761 | Wnt signaling pathways in urological cancers: past decades and still growing |
Q35740118 | ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer |
Q82908362 | [Angiogenesis: the renal cancer model] |
Q54496744 | [Genetics of paragangliomas and pheochromocytomas]. |
Q80687806 | [Molecular biology of the clear cell renal cell carcinoma: principles for a selective treatment] |
Q81886345 | [Von-Hippel-Lindau (VHL) protein function by initiation and progression of renal cancer] |
Q38328912 | aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia |
Q26775483 | c-Met as a Target for Personalized Therapy |
Q35161430 | cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma |
Q61813696 | loss sensitizes cells to PI3Kβ and AKT inhibition |
Q52922662 | mRNA expression profiles of methylated APAF-1 and DAPK-1 tumor suppressor genes uncover clear cell renal cell carcinomas with aggressive phenotype. |
Q35551941 | miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma |
Q35891149 | miR-210: fine-tuning the hypoxic response |
Q41353753 | p53 status in spontaneous and dimethylnitrosamine-induced renal cell tumors from rats |
Q54551413 | pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma. |
Q50913975 | pVHL suppresses Akt/β-catenin-mediated cell proliferation by inhibiting 14-3-3ζ expression. |
Q44480238 | pVHL-independent ubiquitination of HIF1alpha and its stabilization by cobalt ion. |
Q34753344 | pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation |
Q28180159 | von Hippel-Lindau disease |
Q73567751 | von Hippel-Lindau disease |
Q73979850 | von Hippel-Lindau disease |
Q73492405 | von Hippel-Lindau disease gene alterations associated with endolymphatic sac tumor |
Q53456957 | von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens. |
Q24622030 | von Hippel-Lindau disease: a clinical and scientific review |
Q35117749 | von Hippel-Lindau disease: recent advances and therapeutic perspectives. |
Q35139869 | von Hippel-Lindau exonic methylation analysis using MALDI-TOF mass spectrometry. |
Q53428747 | von Hippel-Lindau gene mutations in N-nitrosodimethylamine-induced rat renal epithelial tumors. |
Q46478024 | von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma |
Q44548991 | von Hippel-Lindau protein complex is regulated by cell density |
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