Evidence for aldosterone-dependent growth of renal cell carcinoma

scientific article published on 7 May 2014

Evidence for aldosterone-dependent growth of renal cell carcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/IEP.12074
P932PMC publication ID4170966
P698PubMed publication ID24802662

P2093author name stringSarah Galbraith
Susan Bray
Lesley Christie
Stewart Fleming
Sharon King
P2860cites workMineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type II expression in renal cell neoplasms: a tissue microarray and quantitative RT-PCR studyQ46647721
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutationsQ48396942
Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27.Q54119033
Frequency and types of point mutation at the 12th codon of the c-Ki-ras gene found in pancreatic cancers from Japanese patients.Q55397198
Prevalence of ras gene mutations in human colorectal cancersQ59088716
High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomasQ69506614
The impact of genetics on the classification of renal carcinomaQ70567817
Spontaneous development of malignant phase hypertension in transgenic Ren-2 ratsQ72118265
K-ras 4A and 4B are co-expressed widely in human tissues, and their ratio is altered in sporadic colorectal cancerQ80136633
Renal cell carcinoma and arterial hypertensionQ83274928
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaQ24337664
Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in ratsQ28317226
Rational siRNA design for RNA interferenceQ29614450
Captopril restores transforming growth factor-beta type II receptor and sensitivity to transforming growth factor-beta in murine renal cell cancer cellsQ31931162
Is cancer related to hypertension or to its treatment?Q33697736
Renal cancer genetics: von Hippel Lindau and other syndromesQ33759957
Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.Q33843488
Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinomaQ34320299
New ideas about aldosterone signaling in epitheliaQ34552939
Contemporary epidemiology of renal cell cancerQ34598015
The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231.Q34696613
Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?Q34749837
While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.Q34989253
Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in miceQ35108463
Fumarate hydratase mutations and predisposition to cutaneous leiomyomas, uterine leiomyomas and renal cancerQ36200399
Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas.Q36643591
Human Colon Carcinoma Ki-ras2 Oncogene and Its Corresponding Proto-OncogeneQ36946669
Epidemiology of kidney cancerQ36968943
An investigation of risk factors for renal cell carcinoma by histologic subtype in two case-control studiesQ37030432
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profilingQ38304283
Aldosterone induces myofibroblast EGF secretion to regulate epithelial colonic permeabilityQ39184355
Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinomaQ40409431
Captopril inhibits tumour growth in a xenograft model of human renal cell carcinomaQ41053553
Point mutation at codon 12 of the Ki-ras gene in a primary breast carcinoma and the MDA-MB-134 human mammary carcinoma cell lineQ41733713
Infrequent ras oncogene point mutations in renal cell carcinomaQ41748786
Receptor tyrosine kinases mediate epithelial Na(+) channel inhibition by epidermal growth factorQ42468468
Mutations of the VHL tumour suppressor gene in renal carcinomaQ42806703
Renal carcinoma with giant mitochondria associated with germ-line mutation and somatic loss of the succinate dehydrogenase B geneQ43066526
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular diseaseQ43670943
Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signalingQ44185650
Regulation of Na+ transport by aldosterone: signaling convergence and cross talk between the PI3-K and MAPK1/2 cascadesQ44811028
Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signalingQ44950440
Mutations in the ras protooncogenes are rare events in renal cell cancerQ44993791
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomasQ45345804
Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channelQ46490014
P433issue4
P304page(s)244-250
P577publication date2014-05-07
P1433published inInternational Journal of Experimental PathologyQ15750807
P1476titleEvidence for aldosterone-dependent growth of renal cell carcinoma
P478volume95

Reverse relations

cites work (P2860)
Q58544609Association of Papillary Thyroid Carcinoma with Primary Aldosteronism
Q27340035GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells
Q42153567Pressuromodulation at the cell membrane as the basis for small molecule hormone and peptide regulation of cellular and nuclear function
Q90219809Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma
Q55003080Role of epigenetic factors in the selection of the alternative splicing isoforms of human KRAS in colorectal cancer cell lines.

Search more.